Invitation dr. langlais
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Robert Langlais, a Professor Emeritus and Board Certified Oral and Maxillofacial Radiologist, will give a presentation on March 5th from 6-9pm at the Patterson Branch located in Richmond, BC. The presentation will discuss the utility and superiority of panoramic bitewings and periapicals made with specific panoramic machines, and how some of these panoramics can later be converted to CBCT/3D. Dr. Langlais will also review several CBCT cases to illustrate CBCT's unique utility in various common clinical situations. Light refreshments will be provided.
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Your smile is beautiful.
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Test bank for karp s cell and molecular biology 9th edition by gerald karp.pdf
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Breast cancer in postmenopausal women with hormone receptor-positive (HR+) status is a common and complex condition that necessitates a multifaceted approach to management. HR+ breast cancer means that the cancer cells grow in response to hormones such as estrogen and progesterone. This subtype is prevalent among postmenopausal women and typically exhibits a more indolent course compared to other forms of breast cancer, which allows for a variety of treatment options.
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Treatment Options
Endocrine Therapy
Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include:
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
Chemotherapy
Chemotherapy is generally reserved for patients with high-risk features, such as large tumor size, high-grade histology, or extensive lymph node involvement. Regimens often include anthracyclines and taxanes.
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Invitation dr. langlais
- 1. Date March 5, 2012 Time 6:00- 9:00pm Location Patterson Branch #110 - 6651 Fraserwood Place, Richmond, BC.V6W 1J3 Light refreshments & appetizers Robert Langlais DDS, MS, FRCD(C) Board Certified Oral & Maxillofacial Radiologist __________________ Dr Langlais is a Professor Emeritus at the University Of Texas Health Science Center Dental School and is currently completing his research in Radiological Sciences for a PhD degree at the University of the Western Cape in Capetown South Africa. He has made more than 550 presentations on all continents of the world, published 120 scientific papers and 11 first edition textbooks on the subjects of Oral Medicine and Dental Radiology. Dr. Langlais will share his thoughts and research on the utility, convenience and superiority of panoramic bitewings and periapicals which are made possible using Specific Panoramic machines. Some of these panoramics can be later converted to CBCT/3D. He will finish up with several CBCT cases to illustrate CBCT’s unique utility in various common but perplexing clinical situations. EXPAND YOUR DIAGNOSTIC IMAGING CAPABILITIES YOU’VE GOT QUESTIONS, WE’VE GOT ANSWERS! ASK A RADIOLOGIST ABOUT: • Panoramic Imaging • Cephs • Bitewings • Tomography • ConeBeam RSVP Call Kathy Hogarth at 604-247-1991 or 800-663-1922 FEE $30.00 per person, N/C for Patterson Plus Customers CE Credit available Event for Dentists/Specialists