Innate immune svstem 1. Explain and describe the various lines of defense against pathogens. 2.
Outline the major components of the innate immune system including what initiates and the
benefits of each defense . 3. Outline the sequence of events that occurs in phagocytosis. 4.
Describe the general complement reactions and list their 5 benefits. 5. List the origins and
actions of several cytokines including interleukins, histamines, leukotrienes, prostaglandins,
tumor necrosis factor and colony stimulating factor. 6. Outline and describe the events occurring
in the inflammation response to an invading bacterium. 7. Differentiate between the populations
of WBCs (granulocytes and agranulocytes) in terms of morphology and physiological effect. 8.
Describe the anatomy and physiology of the primaryand secondary lymphatic organs including:
bone marrow, thymus, lymph nodes, spleen, peyers patch and tonsils 9. Explain the relationship
between hapten and antigen 10. Identify key properties of innate immunity and be able to
distinguish them from adaptive immunity. Adaptive Immune Response 1. Distinguish between
the 2 divisions of the adaptive response: humoral \& cell mediated 2. Identify the function of the
key cells and receptors associated with adaptive immunity. 3. Identify the characteristics and
chemical composition of antigens 4. Differentiate between endogenous and exogenous
infections. 5. Explain the clonal selection theory of antibody specificity and diversity. 6.
Diagram the origin and development of B and T.lymphocytes. 7. Diagram the 5 steps of the
adaptive immune response leading from an undifferentiated T cell to a sensitized cytotoxic T cell
and an undifferentiated B cell to an antibody producing plasma cell. 8. Compare and contrast the
primary and secondary response to antigens Problems of the lmmune.System 1. Compare atopic
allergy to anaphylaxis. 2. Outline the major characteristics of the 4 types of hypersensitivites and
provide examples of each. 3. 1. ist 3 different types of primary immunodeficiency indicating how
humoral and cell-mediated immunity is affected in each case and how each may be treated. 4.
State what is meant by secondary immunodeficiency and list 4 possible contributing factors..
Innate immune svstem 1- Explain and describe the various lines of defe.pdf
1. Innate immune svstem 1. Explain and describe the various lines of defense against pathogens. 2.
Outline the major components of the innate immune system including what initiates and the
benefits of each defense . 3. Outline the sequence of events that occurs in phagocytosis. 4.
Describe the general complement reactions and list their 5 benefits. 5. List the origins and
actions of several cytokines including interleukins, histamines, leukotrienes, prostaglandins,
tumor necrosis factor and colony stimulating factor. 6. Outline and describe the events occurring
in the inflammation response to an invading bacterium. 7. Differentiate between the populations
of WBCs (granulocytes and agranulocytes) in terms of morphology and physiological effect. 8.
Describe the anatomy and physiology of the primaryand secondary lymphatic organs including:
bone marrow, thymus, lymph nodes, spleen, peyers patch and tonsils 9. Explain the relationship
between hapten and antigen 10. Identify key properties of innate immunity and be able to
distinguish them from adaptive immunity. Adaptive Immune Response 1. Distinguish between
the 2 divisions of the adaptive response: humoral & cell mediated 2. Identify the function of the
key cells and receptors associated with adaptive immunity. 3. Identify the characteristics and
chemical composition of antigens 4. Differentiate between endogenous and exogenous
infections. 5. Explain the clonal selection theory of antibody specificity and diversity. 6.
Diagram the origin and development of B and T.lymphocytes. 7. Diagram the 5 steps of the
adaptive immune response leading from an undifferentiated T cell to a sensitized cytotoxic T cell
and an undifferentiated B cell to an antibody producing plasma cell. 8. Compare and contrast the
primary and secondary response to antigens Problems of the lmmune.System 1. Compare atopic
allergy to anaphylaxis. 2. Outline the major characteristics of the 4 types of hypersensitivites and
provide examples of each. 3. 1. ist 3 different types of primary immunodeficiency indicating how
humoral and cell-mediated immunity is affected in each case and how each may be treated. 4.
State what is meant by secondary immunodeficiency and list 4 possible contributing factors.
