Malignmesotelioma can be causedbyserozalleaves of pleura, pericard, peritoneum, tunicavaginalisor testis. Inthe United States, about 2500 newcases of mesothelioma are reported each year.
Abdominal Splenosiscausing Hydronephrosis- A Case Reportsemualkaira
Splenosis is anuncommenprocess ofintra abdominal or extra abdominal splenic tissue seeding, mostly post traumatic.The issueof splenosismostly comesupinpatientspresentingwith suspicious nodules inthe abdominal or chest cavity. It is exactly these patients with a history of blunt abdominal trauma who should be considered as candidates for having splenosis and should be screened with a proper medical history and with the use of novel non invasive imaging modalities thus sparing the patients unnecessary and potentially dangerous procedures.
Abdominal Splenosiscausing Hydronephrosis- A Case Reportsuppubs1pubs1
Splenosis is anuncommenprocess ofintra abdominal or extra abdominal splenic tissue seeding, mostly post traumatic.The issueof splenosismostly comesupinpatientspresentingwith suspicious nodules inthe abdominal or chest cavity. It is exactly these patients with a history of blunt abdominal trauma who should be considered as candidates for having splenosis and should be screened with a proper medical history and with the use of novel non invasive imaging modalities thus sparing the patients unnecessary and potentially dangerous procedures.
This document discusses the role of surgery in cancer management. It covers how surgery is used for prevention, diagnosis, staging, treatment and palliation of cancer. Surgery has evolved from being the only treatment to one component of a multidisciplinary approach. It addresses the historical development of surgical oncology and examples of current and potential future surgical techniques for cancer.
Breast Desmoid Tumor with Spectacular Evolution : A Case Report and Review of...semualkaira
Desmoid tumors or aggressive fibromatosis of the breast, are a rare entity, representing less than
0.2% of all primary breast tumors. The clinical presentation and evolution can mimic a malignant
carcinoma, with the notable difference that a desmoid tumor cannot generate distant metastases. The
aim of the treatment is to achieve local control of this tumor, which can be highly aggressive by
deeply infiltrating surrounding structures, and frequently reoccurs after resection. Both the tumor and
its treatment may cause significant morbidity, causing a real therapeutic challenge.
Breast Desmoid Tumor with Spectacular Evolution : A Case Report and Review of...semualkaira
Desmoid tumors or aggressive fibromatosis of the breast, are a rare entity, representing less than 0.2% of all primary breast tumors. The clinical presentation and evolution can mimic a malignant carcinoma, with the notable difference that a desmoid tumor cannot generate distant metastases.
Breast Desmoid Tumor with Spectacular Evolution : A Case Report and Review of...semualkaira
Desmoid tumors or aggressive fibromatosis of the breast, are a rare entity, representing less than 0.2% of all primary breast tumors. The clinical presentation and evolution can mimic a malignant carcinoma, with the notable difference that a desmoid tumor cannot generate distant metastases
This document describes a case study of a 49-year-old woman who presented with right chest pain and repeated hypoglycemic attacks. Imaging revealed a 10cm solitary fibrous tumor (SFT) of the right pleura. The patient underwent thoracotomy and complete resection of the encapsulated tumor. Histological and immunohistochemical examination confirmed the diagnosis of benign pleural SFT. The patient's hypoglycemic episodes were attributed to Doege-Potter syndrome, a rare paraneoplastic syndrome caused by inappropriate IGF-II secretion from large SFTs. Complete surgical resection is the treatment of choice for SFT and resulted in resolution of the patient's symptoms.
Primary mediastinal liposarcoma of the superior, middle, and anterior mediast...Mary Ondinee Manalo Igot
Primary mediastinal liposarcoma of the superior, middle, and anterior mediastinum
https://www.actamedicaphilippina.org/issue/1102
Abdominal Splenosiscausing Hydronephrosis- A Case Reportsemualkaira
Splenosis is anuncommenprocess ofintra abdominal or extra abdominal splenic tissue seeding, mostly post traumatic.The issueof splenosismostly comesupinpatientspresentingwith suspicious nodules inthe abdominal or chest cavity. It is exactly these patients with a history of blunt abdominal trauma who should be considered as candidates for having splenosis and should be screened with a proper medical history and with the use of novel non invasive imaging modalities thus sparing the patients unnecessary and potentially dangerous procedures.
Abdominal Splenosiscausing Hydronephrosis- A Case Reportsuppubs1pubs1
Splenosis is anuncommenprocess ofintra abdominal or extra abdominal splenic tissue seeding, mostly post traumatic.The issueof splenosismostly comesupinpatientspresentingwith suspicious nodules inthe abdominal or chest cavity. It is exactly these patients with a history of blunt abdominal trauma who should be considered as candidates for having splenosis and should be screened with a proper medical history and with the use of novel non invasive imaging modalities thus sparing the patients unnecessary and potentially dangerous procedures.
This document discusses the role of surgery in cancer management. It covers how surgery is used for prevention, diagnosis, staging, treatment and palliation of cancer. Surgery has evolved from being the only treatment to one component of a multidisciplinary approach. It addresses the historical development of surgical oncology and examples of current and potential future surgical techniques for cancer.
Breast Desmoid Tumor with Spectacular Evolution : A Case Report and Review of...semualkaira
Desmoid tumors or aggressive fibromatosis of the breast, are a rare entity, representing less than
0.2% of all primary breast tumors. The clinical presentation and evolution can mimic a malignant
carcinoma, with the notable difference that a desmoid tumor cannot generate distant metastases. The
aim of the treatment is to achieve local control of this tumor, which can be highly aggressive by
deeply infiltrating surrounding structures, and frequently reoccurs after resection. Both the tumor and
its treatment may cause significant morbidity, causing a real therapeutic challenge.
Breast Desmoid Tumor with Spectacular Evolution : A Case Report and Review of...semualkaira
Desmoid tumors or aggressive fibromatosis of the breast, are a rare entity, representing less than 0.2% of all primary breast tumors. The clinical presentation and evolution can mimic a malignant carcinoma, with the notable difference that a desmoid tumor cannot generate distant metastases.
Breast Desmoid Tumor with Spectacular Evolution : A Case Report and Review of...semualkaira
Desmoid tumors or aggressive fibromatosis of the breast, are a rare entity, representing less than 0.2% of all primary breast tumors. The clinical presentation and evolution can mimic a malignant carcinoma, with the notable difference that a desmoid tumor cannot generate distant metastases
This document describes a case study of a 49-year-old woman who presented with right chest pain and repeated hypoglycemic attacks. Imaging revealed a 10cm solitary fibrous tumor (SFT) of the right pleura. The patient underwent thoracotomy and complete resection of the encapsulated tumor. Histological and immunohistochemical examination confirmed the diagnosis of benign pleural SFT. The patient's hypoglycemic episodes were attributed to Doege-Potter syndrome, a rare paraneoplastic syndrome caused by inappropriate IGF-II secretion from large SFTs. Complete surgical resection is the treatment of choice for SFT and resulted in resolution of the patient's symptoms.
Primary mediastinal liposarcoma of the superior, middle, and anterior mediast...Mary Ondinee Manalo Igot
Primary mediastinal liposarcoma of the superior, middle, and anterior mediastinum
https://www.actamedicaphilippina.org/issue/1102
IRF5 Promotes the Progression of Hepatocellular Carcinoma and is Regulated by...NainaAnon
1. The study found that IRF5 was upregulated in hepatocellular carcinoma (HCC) tissues compared to normal tissues based on mRNA and protein levels.
2. Overexpression of IRF5 promoted the growth and colony formation of HCC cells in vitro, while silencing IRF5 inhibited HCC cell growth and proliferation.
3. TRIM35 was found to interact with and promote the degradation of IRF5. TRIM35 expression was negatively correlated with IRF5 levels in HCC clinical samples.
Trimodal Management of Locally Invasive Urinary Bladder CancerNainaAnon
To evaluate the response of the modern bladder-preservation treatment modality; Trimodal Therapy (TMT) in Muscle-Invasive Bladder Cancer (MIBC). Aiming at bladder preservation in MIBC, TMT was to offer a quality- of-life advantage and avoid potential morbidity and mortality of Radical Cystectomy (RC) without compromising oncologic outcomes.
Alterations of Gut Microbiota From Colorectal Adenoma to CarcinomaNainaAnon
The document analyzes differences in gut microbiota between healthy individuals, those with colorectal adenomas (CRA), and those with colorectal cancer (CRC). 16S rRNA sequencing was performed on tissue samples from 11 individuals in each group. Microbial diversity was lower in CRA patients and higher in CRC patients compared to healthy individuals. The relative abundance of Fusobacteria was lower in CRA and higher in CRC. This suggests alterations in gut microbiota occur from adenoma to carcinoma, with Fusobacteria potentially playing a role in colorectal cancer development.
Prognosis of Invasive Micropapillary Carcinoma of the Breast Analyzed by Usin...NainaAnon
Invasive micropapillary carcinoma (IMPC) is a rare type of breast cancer with high frequency of regional lymph node metastasis. However, the prognosis of IMPC has remained controversial for decades. We aimed to compare the differences of prognosis between IMPC and Invasive ductal carcinoma(IDC) of the breast by utilizing Surveillance, Epidemiology, and End Results (SEER) database.
Uretero-Enteric Anastomosis Stricture after Urinary Diversion; Detailed Analy...NainaAnon
To report the lessons we have learned in the management of uretero-enteric anastomosis stricture (UEAS) in a tertiary urology center over a decade of experience.
Clinic Correlation and Prognostic Value of P4HB and GRP78 Expression in Gastr...NainaAnon
Prolyl 4-hydroxylase, beta polypeptide (P4HB) and Glucose‑regulated protein 78 (GRP78) represent for poor prognosis of various cancers, while rare research investigate correlation of them. This study aimed to explore correlation and prognostic value of them in gastric cancer (GC).
Combined Analysis of Micro RNA and Proteomic Profiles and Interactions in Pat...NainaAnon
The Liquid Mass System(LMS) includes an Easy nLC1000 (Thermo Fisher) coupled ultra-high resolution mass spectrometer Orbitrap Fusion Lumos (Thermo Fisher) with a Thermo Fisher electrospray source. Each injection is sent to a preset column (Acclaim PepMap C18, 100 μm x 2 cm, Thermo Scientific) for adsorption at a flow rate of 3 L/min. The sample is then sent to the analyzer column (Acclaim PepMap C18, 75 μm x 15 cm, Thermo Scientific) for separation
Skeletal muscle channelopathy are rare heterogeneous episodic disorders with marked genotypic and phenotypic variability resulting in periodic paralysis, and falls in young people which often misdiagnosed or undiagnosed due to its rarity, often the symptoms are miscommunicated to the treating phycision due to its episodic nature and not uncommonly physical examination by the time patient attend the clinic or hospital will be unremarkable apart from periodic muscle paralysis where patient will presented to ED with flaccid weakness,
The Use of the Infrared Laser Therapy of 890-910 NM for the Treatment Breast ...NainaAnon
The document summarizes experimental and clinical research on using infrared laser therapy between 890-910 nm to treat breast cancer. Experimental studies showed laser therapy inhibited tumor growth in mice and rats, with the most effective dose being 0.46 J/cm2. Clinical studies involved 136 patients with breast cancer divided into 3 groups: those receiving laser therapy before surgery, after surgery, or as the sole treatment. Laser therapy reduced postoperative complications, improved immune function and quality of life, and increased survival time. Histological analysis found over 50% of tumor tissue disappeared due to necrosis and fibrosis with effective laser treatment regimens.
The Use of the Infrared Laser Therapy of 890-910 NM for the Treatment Breast ...NainaAnon
The experimental studies were conducted with Walker's carcinosarcoma n256 (from the U.S.A. bank), cancer of the mammary gland (RMK-1). Spontaneous –mice with mammary glands cancer (type B). The tasks were as follows: to study the effect of different doses LLLT on the growth of experimental tumors. Evaluation of the effectiveness by applying LLLT in combination with various chemotherapeutic agents (vincristin, 5-Fu, ciclophosphan). Research of LLLR effect on different types of tumors show that this treatment can be used for tumors-statistic effect and for increasing life-span in animals. Applying LLLR in combination with chemotherapeutic agents causes tumors-static action. The most effective combination was LLLT + vincristin which caused the inhibition of tumor growth in Walker's carcinosarcoma-by 92,87%, in RMK-1 - by 90,29% in comparing to controls. The combination of LLLT with HpD showed - the effect of laser therapy takes place in 30 min before the irradiation and is accompanied by a sharp reduction of the preparation's accumulation in the tumor cells.
Prevalence of Hpv Infection in the Lekoumou and Niari Departments (Congo Braz...NainaAnon
This study aimed to determine the prevalence of HPV infection in women in the Lekoumou and Niari departments of Congo Brazzaville. The researchers collected samples from 100 women aged 16-73 and tested them for HPV. They found an overall HPV prevalence of 29%, with the highest rates (58.3%) in women over 50. No significant associations were found between HPV infection and factors like education level, age of first intercourse, number of sexual partners, or number of pregnancies. The study provides baseline data on HPV prevalence in these regions of Congo to help guide cervical cancer prevention efforts.
Upper Rectal Cancer: Benefit After Preoperative Chemoradiation Versus Upfront...NainaAnon
Upper rectal cancer management is controversial. The present series reports the outcomes of treatment comparing neoadjuvant chemoradiation (NCRT) versus upfront surgery.
Follow-Up Strategies in Focal Liver Lesions And Treatment MethodsNainaAnon
Today, advances in cross-sectional imaging have led to the detection and early recognition of incidental/focal liver lesions (FCL). In approximately 17,000 cases of chest CT, incidental liver lesions were found in 6% [1]. In general, FCL consists of hepatocytes, biliary epithelium, mesenchymal tissue, connective tissue, or metastasized cells from distant sites. Most incidental lesions are benign, some may require careful management and treatment.
Pancreatic Adenocarcinoma with Isolated Venous Involvement: Is Neoadjuvant Tr...NainaAnon
Neoadjuvant Treatment (NAT) is indicated in locally advanced tumors and improves the results of subsequent surgery. In borderline tumors, the place of this preoperative treatment is more controversial, probably because borderline tumors are a heterogeneous group. We focused on the tumors with venous involvement without any arterial involvement and studied the results of neoadjuvant treatment in this particular group.
Predictive Value of Biomarkers Fibrinogen Like Protein-2 and A-Fetoprotein fo...NainaAnon
Data concerning the utility of biomarkers for accurate early HCC detection in cirrhotic patients are lacking. 1.2. Methods: We evaluated 112 consecutive Caucasian cirrhotic patients with (n=28) or without (n=84) concomitant HCC at baseline for serum AFP and plasma fibrinogen like protein-2 (FGL-2) levels. Patients without confirmed HCC at baseline were further followed up every six months with ultrasound and serum AFP levels, according to HCC surveillance program. Imaging as well as histological confirmation of HCC was established in patients with new lesions. Du
The Black Fungus is One of the Bad Consequences of COVID 19NainaAnon
Recently, since the emergence of the Covid 19 pandemic, the whole world has been waiting for what comes after Corona and when that pandemic will disappear and how to get rid of it. Therefore, all countries, whether Arab or foreign, sought to empty scientific research to produce a vaccine to treat this pandemic. These circumstances have inflicted material and human losses for all countries. In an attempt to combat Covid 19 after the vaccine was manufactured, however, the winds are coming in what ships do not desire, so there is a new outbreak, namely the black fungus.
Circulating Tumor Cells and Cell-Free Nucleic Acids as Predictor Factors for ...NainaAnon
Pancreatic cancer remains as one of the most aggressive and deadliest of cancers largely due to formidable challenges in diagnosis and therapy. Consensus standard treatment for patients with nonmetastatic Pancreatic Cancer (PC) incorporates possible neoadjuvant chemotherapy with timely surgical resection and adjuvant chemotherapy. However, despite all the sophistication of modern radiological and endoscopic techniques, the decision regarding operability is often only made intra-operatively, therefore subjecting a patient to unnecessary surgical intervention, and postponing the possibility of starting early chemotherapy.
Research Progress in Chronic Lymphocytic LeukemiaNainaAnon
Cancer is an uncontrolled division of cell occurs due to genetic alterations and mutation. Chronic lymphocytic leukemia is the heterogeneous lymphocytic malignancy worldwide that leads to death. The advancement of genetic analysis techniques and the identification of suitable biomarkers show significant differences in the treatment period. In this paper will discuss the microRNA that is small Non-coding RNAs and is involved in CLL beginning, development, and resistance to therapy and also will explain the stages of CLL.
Genetics of Breast and Ovary Cancers Associated with Hereditary Cancers and t...NainaAnon
Carriers of the BRCA-1/2 mutation have increased and variable risks of Breast Cancer (BC) and ovarian cancer and vary or are modified by common genetic variants and their incidence genetic testing and risk-reducing surgery has increased, they should receive advice and evaluation by the physician with experience in genetics.
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
IRF5 Promotes the Progression of Hepatocellular Carcinoma and is Regulated by...NainaAnon
1. The study found that IRF5 was upregulated in hepatocellular carcinoma (HCC) tissues compared to normal tissues based on mRNA and protein levels.
2. Overexpression of IRF5 promoted the growth and colony formation of HCC cells in vitro, while silencing IRF5 inhibited HCC cell growth and proliferation.
3. TRIM35 was found to interact with and promote the degradation of IRF5. TRIM35 expression was negatively correlated with IRF5 levels in HCC clinical samples.
Trimodal Management of Locally Invasive Urinary Bladder CancerNainaAnon
To evaluate the response of the modern bladder-preservation treatment modality; Trimodal Therapy (TMT) in Muscle-Invasive Bladder Cancer (MIBC). Aiming at bladder preservation in MIBC, TMT was to offer a quality- of-life advantage and avoid potential morbidity and mortality of Radical Cystectomy (RC) without compromising oncologic outcomes.
Alterations of Gut Microbiota From Colorectal Adenoma to CarcinomaNainaAnon
The document analyzes differences in gut microbiota between healthy individuals, those with colorectal adenomas (CRA), and those with colorectal cancer (CRC). 16S rRNA sequencing was performed on tissue samples from 11 individuals in each group. Microbial diversity was lower in CRA patients and higher in CRC patients compared to healthy individuals. The relative abundance of Fusobacteria was lower in CRA and higher in CRC. This suggests alterations in gut microbiota occur from adenoma to carcinoma, with Fusobacteria potentially playing a role in colorectal cancer development.
Prognosis of Invasive Micropapillary Carcinoma of the Breast Analyzed by Usin...NainaAnon
Invasive micropapillary carcinoma (IMPC) is a rare type of breast cancer with high frequency of regional lymph node metastasis. However, the prognosis of IMPC has remained controversial for decades. We aimed to compare the differences of prognosis between IMPC and Invasive ductal carcinoma(IDC) of the breast by utilizing Surveillance, Epidemiology, and End Results (SEER) database.
Uretero-Enteric Anastomosis Stricture after Urinary Diversion; Detailed Analy...NainaAnon
To report the lessons we have learned in the management of uretero-enteric anastomosis stricture (UEAS) in a tertiary urology center over a decade of experience.
Clinic Correlation and Prognostic Value of P4HB and GRP78 Expression in Gastr...NainaAnon
Prolyl 4-hydroxylase, beta polypeptide (P4HB) and Glucose‑regulated protein 78 (GRP78) represent for poor prognosis of various cancers, while rare research investigate correlation of them. This study aimed to explore correlation and prognostic value of them in gastric cancer (GC).
Combined Analysis of Micro RNA and Proteomic Profiles and Interactions in Pat...NainaAnon
The Liquid Mass System(LMS) includes an Easy nLC1000 (Thermo Fisher) coupled ultra-high resolution mass spectrometer Orbitrap Fusion Lumos (Thermo Fisher) with a Thermo Fisher electrospray source. Each injection is sent to a preset column (Acclaim PepMap C18, 100 μm x 2 cm, Thermo Scientific) for adsorption at a flow rate of 3 L/min. The sample is then sent to the analyzer column (Acclaim PepMap C18, 75 μm x 15 cm, Thermo Scientific) for separation
Skeletal muscle channelopathy are rare heterogeneous episodic disorders with marked genotypic and phenotypic variability resulting in periodic paralysis, and falls in young people which often misdiagnosed or undiagnosed due to its rarity, often the symptoms are miscommunicated to the treating phycision due to its episodic nature and not uncommonly physical examination by the time patient attend the clinic or hospital will be unremarkable apart from periodic muscle paralysis where patient will presented to ED with flaccid weakness,
The Use of the Infrared Laser Therapy of 890-910 NM for the Treatment Breast ...NainaAnon
The document summarizes experimental and clinical research on using infrared laser therapy between 890-910 nm to treat breast cancer. Experimental studies showed laser therapy inhibited tumor growth in mice and rats, with the most effective dose being 0.46 J/cm2. Clinical studies involved 136 patients with breast cancer divided into 3 groups: those receiving laser therapy before surgery, after surgery, or as the sole treatment. Laser therapy reduced postoperative complications, improved immune function and quality of life, and increased survival time. Histological analysis found over 50% of tumor tissue disappeared due to necrosis and fibrosis with effective laser treatment regimens.
The Use of the Infrared Laser Therapy of 890-910 NM for the Treatment Breast ...NainaAnon
The experimental studies were conducted with Walker's carcinosarcoma n256 (from the U.S.A. bank), cancer of the mammary gland (RMK-1). Spontaneous –mice with mammary glands cancer (type B). The tasks were as follows: to study the effect of different doses LLLT on the growth of experimental tumors. Evaluation of the effectiveness by applying LLLT in combination with various chemotherapeutic agents (vincristin, 5-Fu, ciclophosphan). Research of LLLR effect on different types of tumors show that this treatment can be used for tumors-statistic effect and for increasing life-span in animals. Applying LLLR in combination with chemotherapeutic agents causes tumors-static action. The most effective combination was LLLT + vincristin which caused the inhibition of tumor growth in Walker's carcinosarcoma-by 92,87%, in RMK-1 - by 90,29% in comparing to controls. The combination of LLLT with HpD showed - the effect of laser therapy takes place in 30 min before the irradiation and is accompanied by a sharp reduction of the preparation's accumulation in the tumor cells.
Prevalence of Hpv Infection in the Lekoumou and Niari Departments (Congo Braz...NainaAnon
This study aimed to determine the prevalence of HPV infection in women in the Lekoumou and Niari departments of Congo Brazzaville. The researchers collected samples from 100 women aged 16-73 and tested them for HPV. They found an overall HPV prevalence of 29%, with the highest rates (58.3%) in women over 50. No significant associations were found between HPV infection and factors like education level, age of first intercourse, number of sexual partners, or number of pregnancies. The study provides baseline data on HPV prevalence in these regions of Congo to help guide cervical cancer prevention efforts.
Upper Rectal Cancer: Benefit After Preoperative Chemoradiation Versus Upfront...NainaAnon
Upper rectal cancer management is controversial. The present series reports the outcomes of treatment comparing neoadjuvant chemoradiation (NCRT) versus upfront surgery.
Follow-Up Strategies in Focal Liver Lesions And Treatment MethodsNainaAnon
Today, advances in cross-sectional imaging have led to the detection and early recognition of incidental/focal liver lesions (FCL). In approximately 17,000 cases of chest CT, incidental liver lesions were found in 6% [1]. In general, FCL consists of hepatocytes, biliary epithelium, mesenchymal tissue, connective tissue, or metastasized cells from distant sites. Most incidental lesions are benign, some may require careful management and treatment.
Pancreatic Adenocarcinoma with Isolated Venous Involvement: Is Neoadjuvant Tr...NainaAnon
Neoadjuvant Treatment (NAT) is indicated in locally advanced tumors and improves the results of subsequent surgery. In borderline tumors, the place of this preoperative treatment is more controversial, probably because borderline tumors are a heterogeneous group. We focused on the tumors with venous involvement without any arterial involvement and studied the results of neoadjuvant treatment in this particular group.
Predictive Value of Biomarkers Fibrinogen Like Protein-2 and A-Fetoprotein fo...NainaAnon
Data concerning the utility of biomarkers for accurate early HCC detection in cirrhotic patients are lacking. 1.2. Methods: We evaluated 112 consecutive Caucasian cirrhotic patients with (n=28) or without (n=84) concomitant HCC at baseline for serum AFP and plasma fibrinogen like protein-2 (FGL-2) levels. Patients without confirmed HCC at baseline were further followed up every six months with ultrasound and serum AFP levels, according to HCC surveillance program. Imaging as well as histological confirmation of HCC was established in patients with new lesions. Du
The Black Fungus is One of the Bad Consequences of COVID 19NainaAnon
Recently, since the emergence of the Covid 19 pandemic, the whole world has been waiting for what comes after Corona and when that pandemic will disappear and how to get rid of it. Therefore, all countries, whether Arab or foreign, sought to empty scientific research to produce a vaccine to treat this pandemic. These circumstances have inflicted material and human losses for all countries. In an attempt to combat Covid 19 after the vaccine was manufactured, however, the winds are coming in what ships do not desire, so there is a new outbreak, namely the black fungus.
Circulating Tumor Cells and Cell-Free Nucleic Acids as Predictor Factors for ...NainaAnon
Pancreatic cancer remains as one of the most aggressive and deadliest of cancers largely due to formidable challenges in diagnosis and therapy. Consensus standard treatment for patients with nonmetastatic Pancreatic Cancer (PC) incorporates possible neoadjuvant chemotherapy with timely surgical resection and adjuvant chemotherapy. However, despite all the sophistication of modern radiological and endoscopic techniques, the decision regarding operability is often only made intra-operatively, therefore subjecting a patient to unnecessary surgical intervention, and postponing the possibility of starting early chemotherapy.
Research Progress in Chronic Lymphocytic LeukemiaNainaAnon
Cancer is an uncontrolled division of cell occurs due to genetic alterations and mutation. Chronic lymphocytic leukemia is the heterogeneous lymphocytic malignancy worldwide that leads to death. The advancement of genetic analysis techniques and the identification of suitable biomarkers show significant differences in the treatment period. In this paper will discuss the microRNA that is small Non-coding RNAs and is involved in CLL beginning, development, and resistance to therapy and also will explain the stages of CLL.
Genetics of Breast and Ovary Cancers Associated with Hereditary Cancers and t...NainaAnon
Carriers of the BRCA-1/2 mutation have increased and variable risks of Breast Cancer (BC) and ovarian cancer and vary or are modified by common genetic variants and their incidence genetic testing and risk-reducing surgery has increased, they should receive advice and evaluation by the physician with experience in genetics.
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Promoting Wellbeing - Applied Social Psychology - Psychology SuperNotesPsychoTech Services
A proprietary approach developed by bringing together the best of learning theories from Psychology, design principles from the world of visualization, and pedagogical methods from over a decade of training experience, that enables you to: Learn better, faster!
Cell Therapy Expansion and Challenges in Autoimmune DiseaseHealth Advances
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
Osteoporosis - Definition , Evaluation and Management .pdfJim Jacob Roy
Osteoporosis is an increasing cause of morbidity among the elderly.
In this document , a brief outline of osteoporosis is given , including the risk factors of osteoporosis fractures , the indications for testing bone mineral density and the management of osteoporosis
Histololgy of Female Reproductive System.pptxAyeshaZaid1
Dive into an in-depth exploration of the histological structure of female reproductive system with this comprehensive lecture. Presented by Dr. Ayesha Irfan, Assistant Professor of Anatomy, this presentation covers the Gross anatomy and functional histology of the female reproductive organs. Ideal for students, educators, and anyone interested in medical science, this lecture provides clear explanations, detailed diagrams, and valuable insights into female reproductive system. Enhance your knowledge and understanding of this essential aspect of human biology.
TEST BANK For Community Health Nursing A Canadian Perspective, 5th Edition by...Donc Test
TEST BANK For Community Health Nursing A Canadian Perspective, 5th Edition by Stamler, Verified Chapters 1 - 33, Complete Newest Version Community Health Nursing A Canadian Perspective, 5th Edition by Stamler, Verified Chapters 1 - 33, Complete Newest Version Community Health Nursing A Canadian Perspective, 5th Edition by Stamler Community Health Nursing A Canadian Perspective, 5th Edition TEST BANK by Stamler Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Pdf Chapters Download Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Pdf Download Stuvia Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Study Guide Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Ebook Download Stuvia Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Questions and Answers Quizlet Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Studocu Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Quizlet Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Stuvia Community Health Nursing A Canadian Perspective, 5th Edition Pdf Chapters Download Community Health Nursing A Canadian Perspective, 5th Edition Pdf Download Course Hero Community Health Nursing A Canadian Perspective, 5th Edition Answers Quizlet Community Health Nursing A Canadian Perspective, 5th Edition Ebook Download Course hero Community Health Nursing A Canadian Perspective, 5th Edition Questions and Answers Community Health Nursing A Canadian Perspective, 5th Edition Studocu Community Health Nursing A Canadian Perspective, 5th Edition Quizlet Community Health Nursing A Canadian Perspective, 5th Edition Stuvia Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Pdf Chapters Download Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Pdf Download Stuvia Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Study Guide Questions and Answers Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Ebook Download Stuvia Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Questions Quizlet Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Studocu Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Quizlet Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Stuvia
These lecture slides, by Dr Sidra Arshad, offer a simplified look into the mechanisms involved in the regulation of respiration:
Learning objectives:
1. Describe the organisation of respiratory center
2. Describe the nervous control of inspiration and respiratory rhythm
3. Describe the functions of the dorsal and respiratory groups of neurons
4. Describe the influences of the Pneumotaxic and Apneustic centers
5. Explain the role of Hering-Breur inflation reflex in regulation of inspiration
6. Explain the role of central chemoreceptors in regulation of respiration
7. Explain the role of peripheral chemoreceptors in regulation of respiration
8. Explain the regulation of respiration during exercise
9. Integrate the respiratory regulatory mechanisms
10. Describe the Cheyne-Stokes breathing
Study Resources:
1. Chapter 42, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 36, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 13, Human Physiology by Lauralee Sherwood, 9th edition
The Nervous and Chemical Regulation of Respiration
Incidentally detected peritoneal Mesothelioma in an Inguinalhernia Sacafter an Urgentoperation: Report of a Case
1. Incidentally detected peritoneal Mesothelioma in An
İnguinalhernia Sacafter An Urgentoperation: Report of A Case
Ilhan B*
Department of General Surgery, Istanbul Faculty of Medicine, Istanbul University, Millet Caddesi, 34093 Fatih, Istanbul, Turkey
Volume 1 Issue 5- 2018
Received Date: 15 Sep 2018
Accepted Date: 18 Oct 2018
Published Date: 24 Oct 2018
1. Abstract
Purpose
Malignmesotelioma can be causedbyserozalleaves of pleura, pericard, peritoneum, tunicavagi-
nalisor testis. Inthe United States, about 2500 newcases of mesothelioma are reported each year.
Most frequent type is pleural mesotelioma, second frequent type is peritoneal mesotelioma. The
annual incidence of malignant peritoneal mesothelioma is one in about 1,000,000 people.
Intheetiology of malignant mesothelioma, prevalence of as best osex posure, as well as othere
nviro nmental agents, radiation, chronic pleural and peritoneal inflammation and irritation,
viralagents can be thecause. Malignmeso the liomadetection in theinguinalhernia sac islimit-
edonly in casereports in theliterature. Theaim of thisstudy is topresent a patient, whoneededur-
gentoperationbecause of an etrangulatedinguinalherniaanda casewithmalignmesotelioma in
hernia sac.
Clinics of Oncology
Citation:Ilhan B, Incidentally detected peritoneal Mesothelioma in An İnguinalhernia Sacafter An Urgent-
operation: Report of A Case. Clinics of Oncology. 2018; 1(5): 1-3.
United Prime Publications: http://unitedprimepub.com
*Corresponding Author (s): Burak Ilhan, Department of General Surgery, Istanbul Fac-
ulty of Medicine, Istanbul University, Millet Caddesi, 34093 Fatih, Istanbul, Turkey,
E-mail: burakmd@yahoo.com
Case Presentation
2. Case Presentation
A55 yeras old patient with no know ncommon disease and no
family history admitted to emergency clinic with complaints of
painful swelling in ther ightinguinal region. There was a work-
ing history in the dyefactory. When the etrangule right ingui-
nal hernia findings were detected on the physicalexamination of
the right inguinal region an emergency operation decision was
made for the patient [1-4]. During surgery, massive degenera-
tive elastic mass lesions were detected in the right inguinal her-
nia sac and in dimensions of approximately 3x2 cm (Figure 1).
Mass excision was performed and the inguinal hernia was re-
paired with prolen graft.The pathologic ezamination result was
epitheloid type malignant mesothelioma (Figure 2). The patient
was consulted to medical oncolopgy section and pemetrexed
and cisplatin treatment started to the patient. At the 6th month
computed tomography (CT) revealed a few hypodense nodular
lesions in the liver, splenic flexure, mild wall thickening in the
transverse colon, and free fluid between the intestins. No further
pathology was detected except Positron eemission tomography /
CT except mild hypermetabolic nodular lesions in thelung (nod-
uleswithSUDmax: 3.70, 12 mm in size). The patient was diverted
to medical oncology for further continued therapy of palliative
chemotherapy.
3. Discussion
Most mesothelioma soccur in the pleural or peritoneal space.
Mesotheliomas, which are arising from cell slining hernia su-
tures are very rare [5]. It has been reported that only%7 of all
peritoneal mesothe liomasaccompany inguinal and umbilical
hernia [6]. The absence of specific findings makes it difficult toi-
dentify in a pre-operative process. Most of these tumors are de-
tecting during surgery [7].
Figure 1: Multicyticlesion in hernia sac.
Figure 2: Peritonealmesothelioma (HEX20).