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Implantable Antennas for Biomedical
Applications
Dr. Ashok Kumar Srinivasan
1
1/19/2024
1/19/2024 2
Constantine A. Balanis
Dr. T. Shanmuganantham, Pondicherry University
1/19/2024 3
1/19/2024 4
Chicken 65
Chicken Leg piece
Dielectric Constant
Concept
Fish Curry
Contents
1. Biomedical Applications
2. Implantable Antenna
3. Frequency Bands
4. Motivation
5. Methodology
6. Results and Discussion
7. Wearable Antenna
8. Cell Phone Radiation
5
1/19/2024
1. Biomedical applications
▪ Glucose monitor
▪ Retinal prosthesis
▪ Cardio paces
▪ Blood pressure monitor
6
1/19/2024
Biotelemetry System
Measurements
Temperature
ECG - Heart Rate
EMG - Muscle Rate
EOG - Retinal
EEG - Brain wave
7
1/19/2024
▪ Use in biomedical therapy and monitor various
physiological parameters.
▪ Build wireless communication links between
implantable devices and exterior instruments.
▪ Communication links between medical sensors and
exterior instruments for short range biotelemetry
applications.
▪ Needs low complexity, small size and low power
consumption.
2. Implantable Antenna
8
1/19/2024
▪ MICS band frequency of 402-405MHz.
▪ ISM Band frequency of 433 MHz,
915 MHz,
2.45 GHz and
5.8 GHz
9
1/19/2024
Name Band [MHz] Max. Tx Power [dBm EIRP] Comments
MICS 402.0 – 405.0 -16 Worldwide
ISM 433.1 – 434.8 +7.85 Europe
ISM 868.0 – 868.6 +11.85 Europe
ISM 902.8 – 928.0 +36 w/spreading Not in Europe
ISM 2400.0 – 2483.5 +36 w/spreading Worldwide
ISM 5725.0 – 5875.0 +36 w/spreading Worldwide
WMTS 608.0 – 614.0 +10.8 US only
WMTS 1395.0 – 1400.0 +22.2 US only
WMTS 1427.0 – 1432.0 +22.2 US only
UWB 100.0 – 960.0 US only
UWB 3100.0 – 10600.0 US, UK and Singapore
3. Frequency Bands
Table 1 Unlicensed frequencies available for in body communication
10
1/19/2024
Challenges
▪ Biocompatibility
▪ Miniaturization
▪ Restricted power incident
▪ Low Power Consumption
▪ Communication link characteristics
11
1/19/2024
Fig.4.1 Hospital Environments
12
1/19/2024
4. MOTIVATION
Fig.4.2 Signal transferring to responsible person
13
1/19/2024
Fig.4.3 Implantable antenna for heart rate measurements
14
1/19/2024
5. METHODOLOGY
5.1 Body Simulating Fluid
5.2 Pork Tissue
5.3 Human Body Phantom Liquid
5.4 Antenna Design
15
1/19/2024
Order Reagent
BSF
1000 mL 2000 mL
0 Ultra-pure water 750 mL 1500 mL
1 NaCl 7.996 g 15.92 g
2 NaHCO3 0.350 g 0.700 g
3 KCl 0.224 g 0.448 g
4 K2HPO4・3H2O 0.228 g 0.456 g
5 MgCl2・6H2O 0.305 g 0.610 g
6 1 kmol/m3 HCl 40 cm3 80 cm3
7 CaCl2 0.278 g 0.556 g
8 Na2SO4 0.071 g 0.142 g
9 (CH2OH)3CNH2 6.057 g 12.14 g
10 1 kmol/m3 HCl Appropriate amount for adjusting pH
5.1 BODY SIMULATING FLUID
Table 5.1.1 Preparation of BSF
16
1/19/2024
Fig.5.1.1 Body Simulation Fluid
(a) without mixing HCL (b) with HCL
17
1/19/2024
Fig.5.2.1 Collection of live pork tissue
5.2 Pork Tissue
18
1/19/2024
Fig.5.2.3 Electrical Properties of pork tissue at 2.45GHz (a) permittivity (b) conductivity.
Fig.5.2.2 Dielectric measurement (Pork tissue)
(a) (b)
19
1/19/2024
Tissue Shape State Ingredients
Permittivity &
Conductivity
Ref
Skin Rectangular Gel
Deionized water,
Sugar, agarose
εr = 38, [7]
Scalp Rectangular Gel
Water, salt,
acrylamide, TMEDA,
ammonium per
sulphate.
εr = 28 [9]
Rat Tissue Rectangular Gel
Deionized water,
DGBE, Triton X-100
εr = 45.2 [14]
Skin
Muscle
Fat
Rectangular Gel
Deionized water,
sugar deionized
water, salt, vegetable
oil, flour deionized
water, sugar, salt
εr = 38
εr = 52.7
εr = 5.28
[15]
Table 5.3.1 Phantoms used for testing of implantable antennas
5.3 Human Body Phantom Liquid
20
1/19/2024
Ingredients Skin Fat Muscle
Deionized Water 50% 2.9% 59.5%
NaCl - 0.1% 0.5%
Sugar 50% - 40%
Vegetable oil - 30% -
Flour - 67% -
Table 5.3.2 Preparation of human body phantoms
21
1/19/2024
Fig.5.3.1 Muscle, Skin and Fat Phantom Liquid Fig.5.3.2 Skin tissue phantom liquid
22
1/19/2024
Need for CPW
– Most popular in air environments.
– Few implanted antennas are designed.
– Less dispersion
– Low conductor loss
– Low radiation loss
5.4 Antenna Design Methodology
23
1/19/2024
Features
– Wide bandwidth
– Better impedance matching
– Easy integration with passive & active devices with
monolithic microwave integrated circuits.
24
1/19/2024
• Microstrip Antenna
• PIFA Antenna
6. EM Simulator
1/19/2024 25
1/19/2024 26
Simulation model setup
7. Results and Discussion
27
1/19/2024
7.1 CPW fed crossed bowtie antenna
Fig.7.1.1 Antenna Structure (Dimensions are in mm)
International Journal of Electronics and Communication, Elsevier Publications, Vol.68, 2/2014, pp.158-165
28
1/19/2024
Fig.7.1.3 Simplified equivalent circuit of Fig.7.1.2
Fig.7.1.2 Equivalent Circuit of proposed antenna
International Journal of Electronics and Communication, Elsevier Publications, Vol.68, 2/2014, pp.158-165
29
1/19/2024
International Journal of Electronics and Communication, Elsevier Publications, Vol.68, 2/2014, pp.158-165
30
1/19/2024
Fig.7.1.4 Return Loss Characteristics
International Journal of Electronics and Communication, Elsevier Publications, Vol.68, 2/2014, pp.158-165
31
1/19/2024
Analytical Model Flowchart
Fig.7.1.5 Flow chart
International Journal of Electronics and Communication, Elsevier Publications, Vol.68, 2/2014, pp.158-165
START
Select Dielectric Material
tan and Thickness
Develop a network model of
proposed antenna
Perform input impedance
Extract S-Parameter Vs
Frequency
If
The Frequency Response
acceptable
STOP
YES
NO
32
1/19/2024
Fig. 7.1.6 Analysis Results
International Journal of Electronics and Communication, Elsevier Publications, Vol.68, 2/2014, pp.158-165
(b) Contour region
(a) Boundary model
(c) antenna radiation (d) Radiation View
33
1/19/2024
Fig.7.1.8 Measurement setup
International Journal of Electronics and Communication, Elsevier Publications, Vol.68, 2/2014, pp.158-165
34
1/19/2024
Fig.7.1.9 Measurement setup
International Journal of Electronics and Communication, Elsevier Publications, Vol.68, 2/2014, pp.158-165
35
1/19/2024
Fig.7.1.10 Return Loss Characteristics
International Journal of Electronics and Communication, Elsevier Publications, Vol.68, 2/2014, pp.158-165
36
1/19/2024
Fig.7.1.11 VSWR characteristics
Fig.7.1.12 Radiation Pattern
International Journal of Electronics and Communication, Elsevier Publications, Vol.68, 2/2014, pp.158-165
(a) H-Plane Co Polarization (b) H-Plane Cross Polarization
(c) E-Plane Co Polarization
(d) H-Plane Cross Polarization
37
1/19/2024
1/19/2024 38
Fig.7.1.13 Antenna Gain
-5dBi
3dBi
Fig.7.2.1 Proposed Antenna Structure Dimensions are in mm
Telemedicine and e- Health, Mary Ann Liebert, Inc. Vol.20 No.3, March 2014 .
7.2 CPW fed X Shaped Monopole Antenna
39
1/19/2024
Fig.7.2.2 Equivalent circuit of proposed antenna
Telemedicine and e- Health, Mary Ann Liebert, Inc. Vol.20 No.3, March 2014 .
40
1/19/2024
 
)
//(
)
//
//
(
// 7
6
5
4
3
2
1 Z
Z
Z
Z
Z
Z
Z
Zin +
+
=
Reflection coefficient,
0
0
z
z
z
z
k
in
in
+
−
=
VSWR =
k
k
−
+
1
1
2
1
log
10
k
)
log(
20 k
−
Return loss =
Numerical Calculations
Telemedicine and e- Health, Mary Ann Liebert, Inc. Vol.20 No.3, March 2014 .
41
1/19/2024
Fig.7.2.3 Return Loss Characteristics
Telemedicine and e- Health, Mary Ann Liebert, Inc. Vol.20 No.3, March 2014 .
42
1/19/2024
Fig.7.2.6 Prototype X Shaped Monopole Antenna
Telemedicine and e- Health, Mary Ann Liebert, Inc. Vol.20 No.3, March 2014 .
43
1/19/2024
44
1/19/2024
Some more Examples
45
1/19/2024
Fig. Measurement Setup
1/19/2024 46
Fig. Measurement Setup
Proposed Antenna
Name
Volume
(mm3)
Substrate Frequency
Return
Loss (dB)
Gain
(dBi)
CPW fed Dual V
Shaped 600.6 FR4
915 MHz
2.45 GHz
-13.5
-24
-23
-16
CPW fed Crossed
Bowtie 371.8
Alumina
Ceramic
2.45 GHz -21 -6.5
CPW fed
Rectangular Shaped 238.8 FR4 2.45 GHz -27 -7
CPW fed Crossed
Type Triangular Slot
78
Alumina
Ceramic
2.45 GHz -19 -6
CPW fed H-Slot
Monopole
71.5
Alumina
Ceramic
2.45 GHz -14 -12
CPW fed
X- Monopole
67.6
Alumina
Ceramic
2.45 GHz -20 -17
CPW fed Z-
Monopole
38.675
Alumina
Ceramic
2.45 GHz -30 -14
Table 7.1 Overall Comparison of Proposed Antenna Results
47
1/19/2024
8. Wearable, Textile and Flexible Antennas
Printing and Embroidering
Conductive Plastics & Metallic Yarns
Why Body-Centric Wireless Comms?
• Wearable computers
used in various
applications such as:
– Military
– Healthcare
– Sport
– Education
– Industrial control
– Research
– Fashion
Wearable computers courtesy of Xybernaut, Germany
Motivation
Medical (Elderly Home, ICU, ...) Personal Communication
(Smart Phones, GPS, ...)
Tharaka Dissanayake, et. al.
Integrate antennas and RF devices into clothes or human body
Lanlin Zhang, et. al.
Embroidering onto Fabric
Lanlin Zhang, et. al.
Transmission Line
Lanlin Zhang, et. al.
WiFi System RFID Antenna
Karoliina Koski, et. al.
Characterise, design and test new antennas and RF devices, and
influence from/to human body
Electric field strength with/without shielding.
Radiation pattern
of antenna
placed on chest
Radiation from a stomach implanted
device
• Using different digital
phantom to highlight
subject-specific
propagation characteristics
188
cm
173
cm 161
cm
Hugo American
model
Japanese male
model
Japanese female
model
188
cm
173
cm 161
cm
Hugo American
model
Japanese male
model
Japanese female
model
◆ Radiation performance is
different due to varying
distribution oh lossy
human tissues
Experimental Investigations
54
1/19/2024

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Implantable Antennas for Biomedical Applications

  • 1. Implantable Antennas for Biomedical Applications Dr. Ashok Kumar Srinivasan 1 1/19/2024
  • 2. 1/19/2024 2 Constantine A. Balanis Dr. T. Shanmuganantham, Pondicherry University
  • 4. 1/19/2024 4 Chicken 65 Chicken Leg piece Dielectric Constant Concept Fish Curry
  • 5. Contents 1. Biomedical Applications 2. Implantable Antenna 3. Frequency Bands 4. Motivation 5. Methodology 6. Results and Discussion 7. Wearable Antenna 8. Cell Phone Radiation 5 1/19/2024
  • 6. 1. Biomedical applications ▪ Glucose monitor ▪ Retinal prosthesis ▪ Cardio paces ▪ Blood pressure monitor 6 1/19/2024
  • 7. Biotelemetry System Measurements Temperature ECG - Heart Rate EMG - Muscle Rate EOG - Retinal EEG - Brain wave 7 1/19/2024
  • 8. ▪ Use in biomedical therapy and monitor various physiological parameters. ▪ Build wireless communication links between implantable devices and exterior instruments. ▪ Communication links between medical sensors and exterior instruments for short range biotelemetry applications. ▪ Needs low complexity, small size and low power consumption. 2. Implantable Antenna 8 1/19/2024
  • 9. ▪ MICS band frequency of 402-405MHz. ▪ ISM Band frequency of 433 MHz, 915 MHz, 2.45 GHz and 5.8 GHz 9 1/19/2024
  • 10. Name Band [MHz] Max. Tx Power [dBm EIRP] Comments MICS 402.0 – 405.0 -16 Worldwide ISM 433.1 – 434.8 +7.85 Europe ISM 868.0 – 868.6 +11.85 Europe ISM 902.8 – 928.0 +36 w/spreading Not in Europe ISM 2400.0 – 2483.5 +36 w/spreading Worldwide ISM 5725.0 – 5875.0 +36 w/spreading Worldwide WMTS 608.0 – 614.0 +10.8 US only WMTS 1395.0 – 1400.0 +22.2 US only WMTS 1427.0 – 1432.0 +22.2 US only UWB 100.0 – 960.0 US only UWB 3100.0 – 10600.0 US, UK and Singapore 3. Frequency Bands Table 1 Unlicensed frequencies available for in body communication 10 1/19/2024
  • 11. Challenges ▪ Biocompatibility ▪ Miniaturization ▪ Restricted power incident ▪ Low Power Consumption ▪ Communication link characteristics 11 1/19/2024
  • 13. Fig.4.2 Signal transferring to responsible person 13 1/19/2024
  • 14. Fig.4.3 Implantable antenna for heart rate measurements 14 1/19/2024
  • 15. 5. METHODOLOGY 5.1 Body Simulating Fluid 5.2 Pork Tissue 5.3 Human Body Phantom Liquid 5.4 Antenna Design 15 1/19/2024
  • 16. Order Reagent BSF 1000 mL 2000 mL 0 Ultra-pure water 750 mL 1500 mL 1 NaCl 7.996 g 15.92 g 2 NaHCO3 0.350 g 0.700 g 3 KCl 0.224 g 0.448 g 4 K2HPO4・3H2O 0.228 g 0.456 g 5 MgCl2・6H2O 0.305 g 0.610 g 6 1 kmol/m3 HCl 40 cm3 80 cm3 7 CaCl2 0.278 g 0.556 g 8 Na2SO4 0.071 g 0.142 g 9 (CH2OH)3CNH2 6.057 g 12.14 g 10 1 kmol/m3 HCl Appropriate amount for adjusting pH 5.1 BODY SIMULATING FLUID Table 5.1.1 Preparation of BSF 16 1/19/2024
  • 17. Fig.5.1.1 Body Simulation Fluid (a) without mixing HCL (b) with HCL 17 1/19/2024
  • 18. Fig.5.2.1 Collection of live pork tissue 5.2 Pork Tissue 18 1/19/2024
  • 19. Fig.5.2.3 Electrical Properties of pork tissue at 2.45GHz (a) permittivity (b) conductivity. Fig.5.2.2 Dielectric measurement (Pork tissue) (a) (b) 19 1/19/2024
  • 20. Tissue Shape State Ingredients Permittivity & Conductivity Ref Skin Rectangular Gel Deionized water, Sugar, agarose εr = 38, [7] Scalp Rectangular Gel Water, salt, acrylamide, TMEDA, ammonium per sulphate. εr = 28 [9] Rat Tissue Rectangular Gel Deionized water, DGBE, Triton X-100 εr = 45.2 [14] Skin Muscle Fat Rectangular Gel Deionized water, sugar deionized water, salt, vegetable oil, flour deionized water, sugar, salt εr = 38 εr = 52.7 εr = 5.28 [15] Table 5.3.1 Phantoms used for testing of implantable antennas 5.3 Human Body Phantom Liquid 20 1/19/2024
  • 21. Ingredients Skin Fat Muscle Deionized Water 50% 2.9% 59.5% NaCl - 0.1% 0.5% Sugar 50% - 40% Vegetable oil - 30% - Flour - 67% - Table 5.3.2 Preparation of human body phantoms 21 1/19/2024
  • 22. Fig.5.3.1 Muscle, Skin and Fat Phantom Liquid Fig.5.3.2 Skin tissue phantom liquid 22 1/19/2024
  • 23. Need for CPW – Most popular in air environments. – Few implanted antennas are designed. – Less dispersion – Low conductor loss – Low radiation loss 5.4 Antenna Design Methodology 23 1/19/2024
  • 24. Features – Wide bandwidth – Better impedance matching – Easy integration with passive & active devices with monolithic microwave integrated circuits. 24 1/19/2024 • Microstrip Antenna • PIFA Antenna
  • 27. 7. Results and Discussion 27 1/19/2024
  • 28. 7.1 CPW fed crossed bowtie antenna Fig.7.1.1 Antenna Structure (Dimensions are in mm) International Journal of Electronics and Communication, Elsevier Publications, Vol.68, 2/2014, pp.158-165 28 1/19/2024
  • 29. Fig.7.1.3 Simplified equivalent circuit of Fig.7.1.2 Fig.7.1.2 Equivalent Circuit of proposed antenna International Journal of Electronics and Communication, Elsevier Publications, Vol.68, 2/2014, pp.158-165 29 1/19/2024
  • 30. International Journal of Electronics and Communication, Elsevier Publications, Vol.68, 2/2014, pp.158-165 30 1/19/2024
  • 31. Fig.7.1.4 Return Loss Characteristics International Journal of Electronics and Communication, Elsevier Publications, Vol.68, 2/2014, pp.158-165 31 1/19/2024
  • 32. Analytical Model Flowchart Fig.7.1.5 Flow chart International Journal of Electronics and Communication, Elsevier Publications, Vol.68, 2/2014, pp.158-165 START Select Dielectric Material tan and Thickness Develop a network model of proposed antenna Perform input impedance Extract S-Parameter Vs Frequency If The Frequency Response acceptable STOP YES NO 32 1/19/2024
  • 33. Fig. 7.1.6 Analysis Results International Journal of Electronics and Communication, Elsevier Publications, Vol.68, 2/2014, pp.158-165 (b) Contour region (a) Boundary model (c) antenna radiation (d) Radiation View 33 1/19/2024
  • 34. Fig.7.1.8 Measurement setup International Journal of Electronics and Communication, Elsevier Publications, Vol.68, 2/2014, pp.158-165 34 1/19/2024
  • 35. Fig.7.1.9 Measurement setup International Journal of Electronics and Communication, Elsevier Publications, Vol.68, 2/2014, pp.158-165 35 1/19/2024
  • 36. Fig.7.1.10 Return Loss Characteristics International Journal of Electronics and Communication, Elsevier Publications, Vol.68, 2/2014, pp.158-165 36 1/19/2024 Fig.7.1.11 VSWR characteristics
  • 37. Fig.7.1.12 Radiation Pattern International Journal of Electronics and Communication, Elsevier Publications, Vol.68, 2/2014, pp.158-165 (a) H-Plane Co Polarization (b) H-Plane Cross Polarization (c) E-Plane Co Polarization (d) H-Plane Cross Polarization 37 1/19/2024
  • 39. Fig.7.2.1 Proposed Antenna Structure Dimensions are in mm Telemedicine and e- Health, Mary Ann Liebert, Inc. Vol.20 No.3, March 2014 . 7.2 CPW fed X Shaped Monopole Antenna 39 1/19/2024
  • 40. Fig.7.2.2 Equivalent circuit of proposed antenna Telemedicine and e- Health, Mary Ann Liebert, Inc. Vol.20 No.3, March 2014 . 40 1/19/2024
  • 41.   ) //( ) // // ( // 7 6 5 4 3 2 1 Z Z Z Z Z Z Z Zin + + = Reflection coefficient, 0 0 z z z z k in in + − = VSWR = k k − + 1 1 2 1 log 10 k ) log( 20 k − Return loss = Numerical Calculations Telemedicine and e- Health, Mary Ann Liebert, Inc. Vol.20 No.3, March 2014 . 41 1/19/2024
  • 42. Fig.7.2.3 Return Loss Characteristics Telemedicine and e- Health, Mary Ann Liebert, Inc. Vol.20 No.3, March 2014 . 42 1/19/2024
  • 43. Fig.7.2.6 Prototype X Shaped Monopole Antenna Telemedicine and e- Health, Mary Ann Liebert, Inc. Vol.20 No.3, March 2014 . 43 1/19/2024
  • 47. Proposed Antenna Name Volume (mm3) Substrate Frequency Return Loss (dB) Gain (dBi) CPW fed Dual V Shaped 600.6 FR4 915 MHz 2.45 GHz -13.5 -24 -23 -16 CPW fed Crossed Bowtie 371.8 Alumina Ceramic 2.45 GHz -21 -6.5 CPW fed Rectangular Shaped 238.8 FR4 2.45 GHz -27 -7 CPW fed Crossed Type Triangular Slot 78 Alumina Ceramic 2.45 GHz -19 -6 CPW fed H-Slot Monopole 71.5 Alumina Ceramic 2.45 GHz -14 -12 CPW fed X- Monopole 67.6 Alumina Ceramic 2.45 GHz -20 -17 CPW fed Z- Monopole 38.675 Alumina Ceramic 2.45 GHz -30 -14 Table 7.1 Overall Comparison of Proposed Antenna Results 47 1/19/2024
  • 48. 8. Wearable, Textile and Flexible Antennas Printing and Embroidering Conductive Plastics & Metallic Yarns
  • 49. Why Body-Centric Wireless Comms? • Wearable computers used in various applications such as: – Military – Healthcare – Sport – Education – Industrial control – Research – Fashion Wearable computers courtesy of Xybernaut, Germany
  • 50. Motivation Medical (Elderly Home, ICU, ...) Personal Communication (Smart Phones, GPS, ...) Tharaka Dissanayake, et. al. Integrate antennas and RF devices into clothes or human body Lanlin Zhang, et. al.
  • 51. Embroidering onto Fabric Lanlin Zhang, et. al. Transmission Line Lanlin Zhang, et. al. WiFi System RFID Antenna Karoliina Koski, et. al. Characterise, design and test new antennas and RF devices, and influence from/to human body Electric field strength with/without shielding. Radiation pattern of antenna placed on chest
  • 52. Radiation from a stomach implanted device • Using different digital phantom to highlight subject-specific propagation characteristics 188 cm 173 cm 161 cm Hugo American model Japanese male model Japanese female model 188 cm 173 cm 161 cm Hugo American model Japanese male model Japanese female model ◆ Radiation performance is different due to varying distribution oh lossy human tissues