This study investigates the impact of cross aisles on travel times in rectangular warehouse layouts, particularly focusing on the design of equally and unequally spaced cross aisles. Findings indicate that establishing equally spaced cross aisles can significantly reduce order picking travel times, while the benefits of unequally spaced cross aisles are minimal. A look-up table is provided to determine the optimal number of equally spaced cross aisles based on warehouse length and requirements.