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![Asian Journal of Obstetrics Gynecology
From the desk oF group editor-in-chieF
Asian Journal of Obs Gynae Practice was
Paracetamol for Fever in Pregnancy launched in December 1996 as the first
of the series of specialized journals under
the ‘Asian Series’. The journal covers a
Dr KK Aggarwal
Padma Shri and Dr BC Roy National Awardee
Sr Physician and Cardiologist, Moolchand Medcity
whole range of topics in the specialty,
President, Heart Care Foundation of India
Group Editor-in-Chief, IJCP Group
Editor-in-Chief, eMedinewS
from antenatal care to general gynecology
to operative obstetrics including its
Chairman Ethical Committee, Delhi Medical Council
Director, IMA AKN Sinha Institute (08-09)
Hony. Finance Secretary, IMA (07-08)
Chairman, IMA AMS (06-07)
President, Delhi Medical Association (05-06)
emedinews@gmail.com subspecialities of Urogynecology, Oncology
http//twitter.com/DrKKAggarwal
Krishan Kumar Aggarwal (Facebook)
and Reproductive Endocrinology.
E
levation of maternal core temperature from a febrile illness or other source (e.g. hot tub) in the first
trimester of pregnancy may be associated with an increased risk for neural tube defects or miscarriage.
The National Birth Defects Prevention Study, however observed that among women with infection-related
fever, use of paracetamol was associated with a statistically significant reduction in neural tube defects, as well as
Dr Alka Kriplani, Professor, Dept. of
cleft lip/palate and gastroschisis. The data support the safety of paracetamol for relief of fever and pain; however,
the reduction in birth defects should be confirmed in other studies before the drug can be recommended to febrile Obstetrics and Gynecology, AIIMS, is the
women for this purpose.
Evidence Editor of the journal.
To investigate whether exposure during the first trimester of pregnancy to single-ingredient acetaminophen
increases the risk of major birth defects. Data from the National Birth Defects Prevention Study, a population-
based, case-control study, were used. Women who delivered between January 1, 1997, and December 31, 2004
Specifications
and participated in the telephone interview were included. Type and timing of acetaminophen use were assigned
based on maternal report. Women reporting first-trimester acetaminophen use in a combination product were
excluded, resulting in a total of 11,610 children in the case group and 4,500 children in the control group
for analysis. The prevalence of first-trimester single-ingredient-acetaminophen use was common: 46.9%
(n = 5,440) among women in the case group and 45.8% (n = 2,059) among women in the control group
Readership: 25,000
(p = 0.21). Overall, acetaminophen was not associated with an increased risk of any birth defect. Among women
reporting a first-trimester infection and fever, use of acetaminophen was associated with a statistically significantly
decreased odds ratio (OR) for an encephaly or craniorachischisis (adjusted OR 0.35, 95% confidence interval
[CI] 0.08-0.80), encephalocele (adjusted OR 0.17, 95% CI 0.03-0.87), anotia or microtia (adjusted OR 0.25,
95% CI 0.07-0.86), cleft lip with or without cleft palate (adjusted OR 0.44, 95% CI 0.26-0.75) and gastroschisis
(adjusted OR 0.41, 95% CI 0.18-0.94).
Size: A4
Single-ingredient-acetaminophen use during the first trimester does not appear to increase the risk of major
birth defects. It may decrease the risk of selected malformations when used for a febrile illness. Pages: 48+4
Source: Feldkamp ML, Meyer RE, Krikov S, Botto LD. Obstet Gynecol 2010;115(1):109-15.
Printing: 4+2 color
n n n
Asian Journal of Obs and Gynae Practice, Vol. 1, January-March 2011
Paper: 170/90 GSM Indian Art Paper
Frequency: Quarterly
Cover Price: ` 300/-
Annual subscription ` 1200/-](https://image.slidesharecdn.com/catalougeforprint-13133540950269-phpapp01-110814153637-phpapp01/85/IJCP-Brochure-11-320.jpg)
![Organ Failure Score
Organ system Criteria for failure
Liver Clinically acute liver failure
Hematological WBC count ≤1,000 per µl
Platelet count ≤20,000 per µl
Hematocrit ≤20% and not chronic renal failure
Neurological Glasgow coma score ≤6, in absence of sedation, at any one point in day
Respiratory Respiratory rate ≤ per minute, or ≥49 per minute
PaCO2 0 mmHg
Dependent on ventilator on 4th day of organ system failure (do not apply for first 72 hours of organ system failure)
Cardiovascular Heart rate ≤4 bpm
Mean arterial blood pressure ≤49 mmHg
Occurrence of ventricular tachycardia and/or ventricular fibrillation
Serum pH ≤7.24 with PaCO2 ≤49 mmHg
Renal Urine output ≤479 ml/day, or ≤19 ml during an 8-hour period and serum urea ≥214 mg/dl
Urine output ≤479 ml/day, or ≤19 ml during an 8-hour period and serum creatinine ≥3. mg/dl
Mean arterial blood pressure = [(systolic BP) + (2 × (diastolic BP)]/3
Suggested Readings
1. Chang RW, Jacobs S, Lee B. Predicting outcome among intensive care unit patients using computerised trend analysis of daily Apache II scores corrected for organ
system failure. Intensive Care Med 1988;14:8-66.
2. Garden OJ, Motyl H, Gilmour WH, et al. Prediction of outcome following acute variceal hemorrhage. Br J Surg 198;72:91-.
3. Thomson JN. Laboratory control of anticoagulant therapy. In: Blood Coagulation and Haemostasis, 2nd edition, Thomson JN, (Ed.). Chapter 9. Churchill-Livingstone
1980:279-329.
doctor.
bound
a daily basis.
Specifications
Laminated Cover
Printing - 4+2 Color
Pages - 12-16 + 4 pages
Size - A 4 (8 X 11 inches)
Paper - 210/110 GSM Indian Art Paper
‘Algorithms’ are a much in demand
Algorithms come most handy when a
decision trees and furnish step-by-step
academic gifts for doctors, which contain
clinician confronts a clinical situation on
disease management guidelines to a
Algorithms
Binding - Center Stitch/perfect binding/Hard](https://image.slidesharecdn.com/catalougeforprint-13133540950269-phpapp01-110814153637-phpapp01/85/IJCP-Brochure-31-320.jpg)
![Newsletters
2 Newsletters are a publications of regularly
Herbs frequency. They provide Clinical Updates,
Tinospora cordifolia References
News and Views from across the globe.
efficacy of T cordifolia extract was
evaluated in patients with allergic
1. Badar VA, et al. J Ethnopharmacol. 2005;
English name: Tinospora gulancha/ rhinitis. Results of the study showed 96(3):445-449.
Indian tinospora that T cordifolia treatment brought 2. Rege NN, et al. Phytother Res. 1999;13(4):
Sanskrit name: Guduchi about significant reduction in the 275-291.
symptoms (such as sneezing and nasal 3. Leyon PV, Kuttan G. J Ethnopharmacol.
Habit and Habitat discharge, obstruction, and pruritus) of
allergic rhinitis.1
2004;90(2-3):233-237.
4. Singh N, et al. Immunopharmacol
Tinospora cordifolia, an extensively Immunotoxicol. 2004;26(1):145-162.
T cordifolia is known to possess
spreading glabrous, perennial deciduous 5. Stanely P, et al. J Ethnopharmacol. 2000;
adaptogenic,2 antineoplastic,3
twiner with succulent stems, is 70(1):9-15.
immunomodulatory,4 antidiabetic,5 6. Mathew S, Kuttan G. J Exp Clin Cancer
mainly found in the tropical regions
antioxidant,6 hypolipidemic,7 anti- Res. 1997;16(4):407-411.
of Indian subcontinent and China.
inflammatory, analgesic, diuretic, 7. Stanely Mainzen Prince P, et al.
T cordifolia often grows to a great height gastrointestinal protective,8 antimalarial,9 J Ethnopharmacol. 1999;64(1):53-57.
and climbs up the trunks of large neem and hepatoprotective10 properties. 8. Panchabhai TS, et al. Phytother Res.
trees. Its branches bear long thread- Medicinal Use Many studies have attributed these 2008;22(4):425-441.
like aerial roots, smooth heart-shaped properties of T cordifolia to the 9. Singh RK. J Vector Borne Dis. 2005;42(1):
In Ayurveda, T cordifolia, a potent
leaves, unisexual greenish flowers presence of berberine or the bitter 36-38.
rasayana and rejuvenating agent,
(summer), and red berries (winter). substances. 10. Tasaduq SA, et al. Hum Exp Toxicol.
is used for the treatment of several 2003; 22(12):639-645.
ailments such as general weakness,
Principal Constituents fever, dyspepsia, dysentery, gonorrhea, Product Range
The principal components of T cordifolia secondary syphilis, urinary diseases, Abana, Bonnisan, Diabecon, Diakof,
include tinosporin, tinosporide, cordifol, impotency, gout, viral hepatitis, skin Diarex, Evecare, Geriforte, Koflet,
heptacosanol, clerodane furano diterpene, diseases, and anemia. Mentat, Mentat syrup, Purim, Rumalaya,
diterpenoid furanolactone tinosporidine, In a randomized, double-blind, Rumalaya forte, Septilin, Septilin
columbin, and b-sitosterol. placebo-controlled study, the syrup, Guduchi, and Chyavanaprasha.
Boerhaavia diffusa observed that the antiproliferative
and antiestrogenic properties of
antihepatotoxic, antiasthmatic,
antiurethritis activities.1
and
English name: Spreading hogweed/ B diffusa are effective in the treatment
Boerhavia of estrogen-dependent breast cancers.3 Product Range
Sanskrit name: Punarnava Abana, Bonnisan, Diabecon, Evecare,
A study conducted in Balb/c mice
showed that punarnavine, the active Geriforte, V-Gel, Lukol, Punarnava,
Habit and Habitat alkaloid present in B diffusa, has and Chyavanprasha.
The genus Boerhaavia is found in the immunomodulatory activities that
tropical, subtropical, and temperate increase the total white blood cell References
regions of Australia, China, Egypt, count, bone marrow cellularity, 1. Awasthi LP, Verma HN. Available at: http://
www.agri-history.org/pdf/Boerhaavia.pdf
India, Middle East countries, Pakistan, number of α-esterase positive cells, and
2. Kaur M, Goel RK. Evid Based Complement
Sudan, Sri Lanka, South Africa, and circulating antibody titer and number Alternat Med. 2009.
the United States. Boerhaavia diffusa, a of plaque-forming cells (PFC) in the 3. Sreeja S, Sreeja S. J Ethnopharmacol.
perennial creeping weed native to India, spleen. The study also showed that 2009;126(2):221-225.
is mainly found in the warm regions Medicinal Use punarnavine increased the proliferation 4. Manu KA, Kuttan G. Immunopharmacol
Immunotoxicol. 2009;31(3):377-387.
up to an altitude of 2000 meters in the of splenocytes, thymocytes, and
In Ayurveda, B diffusa has been used 5. Manu KA, Kuttan G. J Exp Ther Oncol.
Himalayan range. It can grow 1 meter bone marrow cells and reduced the
as a diuretic, diaphoretic, laxative, 2008;7(1):17-29.
or more in length. Its roots are stout and expectorant, and a potent antidote lipopolysaccharide-induced elevated 6. Manu KA, et al. Integr Cancer Ther.
fusiform with a woody root stock.1 levels of proinflammatory cytokines
Specifications
to snake and rat bites. It is also used 2007;6(4):381-388.
for the treatment of hepatitis, jaundice, such as TNF-α, IL-1b, and IL-6.4 7. Borrelli F, et al. Planta Med.
Principal Constituents nephrotic syndrome, urinary disorders, B diffusa stimulates the cell-
2005;71(10):928-932.
and stomach ache.1 mediated immune response5 and
The major chemical compounds
isolated from B diffusa include alkaloids In a study, the methanolic extract of has radioprotective effect against
(punarnavine), amino acids, flavonoids, B diffusa roots has been found to possess γ-radiation-induced damage.6 The
glycoproteins, lignans (liriodendron), anticonvulsant activity, probably due active compounds of B diffusa
rotenoids (boeravinones A-F), to its calcium channel antagonistic exhibit spasmolytic,7 anti-inflammatory,
punarnavoside, and ursolic acid.1 action.2 In another study, it is antifibrinolytic, antibacterial, antistress,
Size: A 3 (8 x 11 inches)
Immunosuppressive Properties of Flavonoids Isolated from Boerhaavia diffusa Linn
S Pages: 8
everal plant extracts have been proliferation; mixed lymphocyte culture; of PBMCs, two-way mixed lymphocyte and mRNA transcript levels and
evaluated for their immunomodu- lipopolysaccharide (LPS)-stimulated reactions (MLRs), NK cell cytotoxicity, LPS-stimulated TNF-α production
latory properties. The ethanolic extract nitric oxide production by RAW 264.7; and LPS-induced NO production by in human PBMCs. It also blocked
of Boerhaavia diffusa root has significant and PHA- and LPS-induced interleukin RAW 264.7; however, the hexane the DNA-binding activation of
immunomodulatory effects. Hexane, (IL)-2 and tumor necrosis factor-alpha extract showed no activity. Purified nuclear factor-κB and AP-1, two
Paper: 130 GSM Indian Art Paper
chloroform, and ethanol extracts of (TNF-α) production. Their effects were Bd-I from the ethanolic extract inhibited major transcription factors centrally
B diffusa, and two pure compounds also evaluated in neutrophil superoxide PHA-stimulated proliferation of PBMCs, involved in the expression of IL-2
(eupalitin-3-O-b-D-galactopyranoside production, natural killer (NK) cell two-way MLR, NK cell cytotoxicity, and and IL-2R gene, which are necessary
[Bd-I] and eupalitin [Bd-II]), were cytotoxicity, and nuclear translocation LPS-induced NO production by RAW for T cell activation and proliferation.
evaluated in vitro for their effect on of nuclear factor-kB and AP-1 in 264.7 equally or more effectively than Results of the study showed the selective
Printing: 4 Color
T cell mitogen (phytohemagglutinin; PHA-stimulated human PBMCs. the parent ethanolic extract at equivalent immunosuppressive activity of B diffusa
PHA)-stimulated human peripheral
blood mononuclear cell (PBMC)
Chloroform and ethanol extracts
inhibited PHA-stimulated proliferation
dosage. Bd-I inhibited the production of
PHA-stimulated IL-2 at the protein
leaf extracts present in Bd-I, isolated
and purified from the ethanolic extract.
Source: Pandey R, et al. Int Immunopharmacol. 2005;5(3):541-553.
Binding: Centre Stitch](https://image.slidesharecdn.com/catalougeforprint-13133540950269-phpapp01-110814153637-phpapp01/85/IJCP-Brochure-55-320.jpg)
IJCP Brochure
- 2. IJCP Group startedits journey in June 1990 with its flagship medical journal, the Indian Journal of Clinical Practice, with a brilliant editorial team comprising of doctors and research analysts. Very soon, IJCP grew from this one journal to a Group of Publications. Today, IJCP’s network has traversed borders to win appreciation by the doctors from the different parts of the world. With a wide range of publications, Events & PR, audio & visual, and host of other information packed products, IJCP Group is the preferred partner of not only the Medical fraternity but also the Pharmaceutical companies. But the journey of IJCP does not end here…. We believe this is the beginning of our journey….. Contact us Head Office Dr Veena Aggarwal Mr Nilesh Aggarwal IJCP Publications Pvt. Ltd. Group Executive Editor & Director E-219, Greater Kailash Part - I Joint Managing Director 09818421222 New Delhi - 110048 09811036687
- 3. Our Management Dr KK Aggarwal Padma Shri & Dr B C Roy Awardee CMD, Publisher and Group Editor-in-Chief President, Heart Care Foundation of India emedinews@gmail.com Dr KK Aggarwal is a Senior Consultant Physician and Cardiologist and Dean of the Board of Medical Education Moolchand Medcity, New Delhi. He is the Founder, Trustee and President of Heart Care Foundation of India. Dr. KK Aggarwal has received many prestigious awards, including the Padma Shri and Dr. B C Roy National Award from the 12th President of India, Smt. Pratibha Devisingh Patil, for his unique contributions in the health sector. He is also known as a writer, columnist and expert for newspapers and TV shows. Dr. Mrs. Veena Aggarwal Group Executive Editor & Joint Managing Director Director, Heart Care foundation of India drveenaijcp@gmail.com Dr Veena Aggarwal, besides being a Consultant in Holistic and Antenatal Care, is a Clinical Obstetrician and Gynecologist by profession. Under her dynamic leadership, foresight and quest for perfection, the IJCP Group has crossed many a milestone and is today a leading healthcare communications group.
- 4. Journal Indexed with IndMED www.ijcpgroup.com ISSN 0971-0876 Single Copy Rs. 250/- Indian Journal of CLINICAL IJCP PRACTICE Volume 21, Number 7 R ev w Jo ie u al rn 361-420 Pages December 2010 er Pe Esophageal Ulceration Following Typhoid Fever Dr KK Aggarwal Group Editor-in-Chief
- 5. Indian Journal ofClinical Practice The flagship journal of IJCP Group of From the Desk oF Group eDitor-in-ChieF From the Desk oF Group eDitor-in-ChieF Publications was launched in June 1990 ACS Updates Prostate Cancer Screening Guideline as a monthly medical journal to provide an insight into the proper diagnosis and treatment of diseases and conditions commonly encountered by an Indian physician. IJCP is unquestionably India’s Dr KK Aggarwal Padma Shri and Dr BC Roy National Awardee leading medical journal. Sr Physician and Cardiologist, Moolchand Medcity President, Heart Care Foundation of India Group Editor-in-Chief, IJCP Group Editor-in-chief, eMedinewS Chairman Ethical Committee, Delhi Medical Council Director, IMA AKN Sinha Institute (08-09) Hony. Finance Secretary, IMA (07-08) Chairman, IMA AMS (06-07) President, Delhi Medical Association (05-06) emedinews@gmail.com Specifications http://twitter.com/DrKKAggarwal Krishan Kumar Aggarwal (Facebook) T he American Cancer Society (ACS) has updated its prostate cancer screening guideline. Men should only be screened after they receive information about the uncertainties, risks, and potential benefits associated with prostate cancer screening. Size: A4 Prostate-specific antigen (PSA) testing is now recommended with or without the digital rectal exam (DRE). There is little evidence that the DRE adds significant benefit to the PSA test, except, perhaps, when the PSA is in the borderline range. Pages: 56+4 PSA value of 4.0 ng/ml be used as a reasonable threshold to trigger further evaluation. There is a new recommendation for men with PSA values between 2.5 and 4.0 ng/ml. Twenty-five percent of men with PSA levels between 2.5 and 4.0 ng/ml harbor prostate cancer and physicians should consider an Printing: 4+1 Color individualized risk assessment for these men. Paper: 210/90 GSM Indian Art Paper An individual assessment should take into account non-PSA risk factors, such as race, family history, results of previous biopsies and DRE results. ACS also now recommends that the PSA testing interval be reduced to every other year for men whose PSA level is under 2.5 ng/ml. Such a reduction in testing frequency will lead to significantly reduced false positives, unnecessary biopsies and overdiagnosis, with only a negligible increase in missed cancers. Source: CA Cancer J Clin Published online March 3, 2010. Frequency: Quarterly n n n Readership: 50,000 Cover Price: ` 300/- Indian Journal of Clinical Practice, Vol. 21, No. 9, February 2011 485 Annual Subscription: ` 3500/-
- 6.
- 7. IJCP’s Medinews Launched in June 1992, Medinews is Controlled-Release Tramadol in Chronic Pain India’s first and most comprehensive C hronic pain is different from acute pain. It can be multifactorial; often it may not be possible to find out if Advantages of CR Tramadol medical newspaper. it is nociceptive, neuropathic, idiopathic or all of the above, • Extended duration of action for reduced dosing Medinews features healthcare news as which in turn affects the duration and treatment.1 More frequency than 40-50% of patients in routine practice settings fail to • More constant plasma concentrations for improved achieve adequate relief making chronic pain a particular efficacy and tolerability challenging problem to treat. Besides its impact on quality- of-life (QOL), chronic pain incurs great healthcare costs.2 Available analgesics include nonopioids such as • Improved compliance and therapeutic outcomes The bioavailability of the CR tramadol formulation is an unbiased and well reasoned analysis and covers medical events, nationally acetaminophen, nonsteroidal anti inflammatory drugs (NSAIDs), cyclo oxygenase-2 (COX-2) inhibitors, weak comparable with IR (immediate release) formulations, opioids such as codeine and tramadol and conventional with a half-life 3-4 times longer (16 hours vs 4-6 hours) opioids such as oxycodone and morphine.3 NSAIDs and and an extent of absorption similar to IR tramadol given and internationally in a well-illustrated acetaminophen are the cornerstone of treating most pain thrice-daily.11 conditions. But, their analgesic efficacy varies widely among Tramadol has been widely studied in the treatment of chronic individual patients. Gastrointestinal toxicity is present in pain, such as osteoarthritis, low back pain, cancer pain and 50% of NSAIDs users and 5.4% develop a more serious event requiring hospitalization due to their frequent use.4 NSAIDs may have a possible deleterious effect on articular neuropathic pain.6 CR tramadol is shown to be more effective in terms of analgesia compared to standard formulation of tramadol both six and 12 hours after administration. It also format. Medinews has enjoyed the OFFICIAL PRESS status at premium cartilage metabolism.5 They may affect fluid and electrolyte has fewer adverse effects than the standard formulation.12 balance, causing fluid retention, edema and hypertension.6 A double-blind crossover comparative study has reported Most patients above 65 years have multiple co-morbid disease significant improvement in pain intensity with CR tramadol conditions such as heart disease, diabetes, hypertension, as compared with IR tramadol and higher patient-rated Alzheimer’s and renal disease that significantly complicate treatment of pain.3 treatment effectiveness.13 CR tramadol therefore provides the advantage of around-the-clock analgesic control with reduced dosing frequency which is essential to obtain patient National conferences like APICON, CSI, Tramadol, an Atypical Opioid Analgesic Tramadol is a synthetic, centrally acting analgesic that has compliance in conditions of chronic pain. CR Tramadol in Osteoarthritis AICOG, PEDICON, IMA-CON, IADVL and been used to treat pain effectively in a variety of indications.7 It belongs to the second step of the WHO analgesic ladder. Tramadol has an atypical pharmacological profile with both opioid and monoaminergic mechanisms. It exerts its A chronic degenerative disorder of multifactorial etiology, osteoarthritis (OA) is the second most common rheumatological problem and is the most frequent joint NAPCON for the last 5 years. analgesic effects by complementary mechanisms of action: disease with prevalence of 22-39% in India. Pain along with It binds weakly to µ-receptors and inhibits ascendent pain functional limitation and stiffness are the major symptoms transmission pathways in the spinal cord. At the same time, making OA the most common cause of locomotor disability it stimulates descendent inhibitory pathways by increasing in the elderly.4 Effective pain control is one of the goals release and decreasing re-uptake of noradrenaline and Specifications of treatment,5 which depends on the analgesic efficacy of serotonin.8 The (+) enantiomer is more potent than the treatment and compliance with the dosing regimen.7 the (–) enantiomer in inhibiting serotonin reuptake. On the other hand, the (–) enantiomer is more potent in inhibiting CR tramadol is an efficacious and well-tolerated medication norepinephrine reuptake and increasing presynaptic release. for the treatment of OA pain.11 The American Pain Society This differential interaction between the two enantiomers is recommends tramadol for the management of OA pain synergistic.6 The dual mechanism of action gives tramadol when NSAIDs alone produce inadequate pain relief.11 The Size: A4 Size recommendations of the American Heart Association include an efficacy that is equivalent to codeine, despite a 10-fold lower affinity to µ-receptors.8 Tramadol does not have tramadol, not NSAIDs or COX-2-specific inhibitors, as the typical opioid adverse effects at the respiratory and first-line therapy for musculoskeletal symptoms in patients cardiovascular level and on intestinal motility at therapeutic with cardiovascular disease or risk factors.6 Pages: 12+4/20+4 doses.9 In addition, it avoids the ulcerogenic, renal/cardiac/ hepatic adverse effects of NSAIDs and COX-2 inhibitors. This feature combined with the lower potential for abuse In a 12-week clinical trial of OA of the knee, CR formulation of tramadol provided patients with increased control over the management of their pain, fewer interruptions in sleep or dependence, gives tramadol a significant advantage over and improved compliance.14 Clinical data on tramadol and Paper: 70/130 GSM Indian Art Paper nonopioids and also over conventional opioids, particularly paracetamol indicate that both the parent drug (tramadol) in the elderly.3 and its active metabolite achieved adequate concentrations in Tramadol has a half-life of about 5.5 hours and the usual oral synovial fluid in comparison to paracetamol.15 The results of dosage regimen is 50-100 mg every 4-6 hours (maximum a long-term open label study demonstrated that CR tramadol Printing: 4 Color dose: 400 mg/day). To reduce the frequency of administration is effective for the long-term management of OA pain. and to improve patient compliance, a controlled-release Reductions in pain intensity, improvements in sleep (CR) formulation of tramadol has been developed.10 and functionality and most QOL measures reported in Readership: 1,00,000 Frequency: Monthly Cover Price ` 100/- Advertisement Tariff Annual subscription ` 1200/- Position Dimension (H X W/Cm.) Amount (`/Advt.) Front Solus 15 x 10 ` 40,000 Back Solus 22 x 34 ` 35000 Full Page ` 40,000/- RHS Pages Economy 15 x 10 ` 30,000/- LHS Pages Economy 15 x 10 ` 25,000/-
- 8. Journal Peer Review Journal ISSN 0972-70035 Single Copy Rs. 250/- www.ijcpgroup.com Volume 13, Number 8, December 2010, Pages 197-236 Dr KK Aggarwal Dr Praveen Chandra Group Editor-in-Chief Guest Editor
- 9. Asian Journal ofClinical Cardiology Asian Journal of Clinical Cardiology (AJCC) From the Desk oF Group eDitor-in-ChieF xxxxxxxxxxx is an ambitious attempt by IJCP Group New Test to Predict Cardiac Risk in Healthy Patients to publish a journal of international standards. Highly sensitive assay for cardiac troponin T (cTnT) can predict cardiovascular events in apparently healthy populations. As part of the Dallas Heart Study, cTnT levels were measured using both standard and highly sensitive assays in more than 3,500 patients ages 30 to 65. The results were published in the Dec. 8 Journal of Dr. Praveen Chandra, Interventional Cardiologist, Medanta Medcity is the Editor the American Medical Association 2010. The standard assay found detectable cTnT in only 0.7% of the study participants, while the highly sensitive test found it in 25%. Only 7.5% of people in the lowest cTnT group had left ventricular hypertrophy compared to 48.1% in the highest cTnT group. Mortality also increased from 1.9% in the lowest group to 28.4% in the highest. cTnT was independently associated with all–cause mortality (adjusted hazard ratio, 2.8 in the highest cTnT group). of the journal. Dr Chandra and a network of eminent Indian and international Another study in the same issue tested the highly sensitive cTnT assay’s ability to predict heart failure in more than 4,000 community–dwelling elderly patients. The biomarker was detectable in the majority of patients (66.2%) and associated with an increased risk of heart failure and cardiovascular death at higher concentrations (4.8 deaths per 100 in highest group compared to 1.1 in patients with undetectable levels). This study continued cTnT measurements over time and found that increases of more than 50% were also associated with cardiovascular cardiologists are toiling tirelessly to make events. In both studies, there was significant overlap between cTnT and N–terminal pro–brain–type natriuretic peptide, suggesting that more accurate predictions may be achieved by use of both tests together. AJCC a world class cardiology journal. Specifications Size: A4 Pages: 36+4 Dr KK Aggarwal Padma Shri and Dr BC Roy National Awardee Sr Physician and Cardiologist, Moolchand Medcity President, Heart Care Foundation of India Printing: 4+1 color Group Editor-in-Chief, IJCP Group Editor-in-Chief, eMedinewS Chairman Ethical Committee, Delhi Medical Council Director, IMA AKN Sinha Institute (08-09) Paper: 210/90 GSM Indian Art Paper Hony. Finance Secretary, IMA (07-08) Chairman, IMA AMS (06-07) President, Delhi Medical Association (05-06) emedinews@gmail.com Frequency: Monthly http://twitter.com/DrKKAggarwal Krishan Kumar Aggarwal (Facebook) Readership: 10,000 Asian Journal of Clinical Cardiology, Vol. 13, No. 9, January 2011 237 Cover Price ` 300/- Annual Subscription ` 3500/-
- 10. Journal Editorial Volume : 1 January-March 2011 Indian Journal of Clinical Practice, Vol. 20, No. 6, November 2009
- 11. Asian Journal ofObstetrics Gynecology From the desk oF group editor-in-chieF Asian Journal of Obs Gynae Practice was Paracetamol for Fever in Pregnancy launched in December 1996 as the first of the series of specialized journals under the ‘Asian Series’. The journal covers a Dr KK Aggarwal Padma Shri and Dr BC Roy National Awardee Sr Physician and Cardiologist, Moolchand Medcity whole range of topics in the specialty, President, Heart Care Foundation of India Group Editor-in-Chief, IJCP Group Editor-in-Chief, eMedinewS from antenatal care to general gynecology to operative obstetrics including its Chairman Ethical Committee, Delhi Medical Council Director, IMA AKN Sinha Institute (08-09) Hony. Finance Secretary, IMA (07-08) Chairman, IMA AMS (06-07) President, Delhi Medical Association (05-06) emedinews@gmail.com subspecialities of Urogynecology, Oncology http//twitter.com/DrKKAggarwal Krishan Kumar Aggarwal (Facebook) and Reproductive Endocrinology. E levation of maternal core temperature from a febrile illness or other source (e.g. hot tub) in the first trimester of pregnancy may be associated with an increased risk for neural tube defects or miscarriage. The National Birth Defects Prevention Study, however observed that among women with infection-related fever, use of paracetamol was associated with a statistically significant reduction in neural tube defects, as well as Dr Alka Kriplani, Professor, Dept. of cleft lip/palate and gastroschisis. The data support the safety of paracetamol for relief of fever and pain; however, the reduction in birth defects should be confirmed in other studies before the drug can be recommended to febrile Obstetrics and Gynecology, AIIMS, is the women for this purpose. Evidence Editor of the journal. To investigate whether exposure during the first trimester of pregnancy to single-ingredient acetaminophen increases the risk of major birth defects. Data from the National Birth Defects Prevention Study, a population- based, case-control study, were used. Women who delivered between January 1, 1997, and December 31, 2004 Specifications and participated in the telephone interview were included. Type and timing of acetaminophen use were assigned based on maternal report. Women reporting first-trimester acetaminophen use in a combination product were excluded, resulting in a total of 11,610 children in the case group and 4,500 children in the control group for analysis. The prevalence of first-trimester single-ingredient-acetaminophen use was common: 46.9% (n = 5,440) among women in the case group and 45.8% (n = 2,059) among women in the control group Readership: 25,000 (p = 0.21). Overall, acetaminophen was not associated with an increased risk of any birth defect. Among women reporting a first-trimester infection and fever, use of acetaminophen was associated with a statistically significantly decreased odds ratio (OR) for an encephaly or craniorachischisis (adjusted OR 0.35, 95% confidence interval [CI] 0.08-0.80), encephalocele (adjusted OR 0.17, 95% CI 0.03-0.87), anotia or microtia (adjusted OR 0.25, 95% CI 0.07-0.86), cleft lip with or without cleft palate (adjusted OR 0.44, 95% CI 0.26-0.75) and gastroschisis (adjusted OR 0.41, 95% CI 0.18-0.94). Size: A4 Single-ingredient-acetaminophen use during the first trimester does not appear to increase the risk of major birth defects. It may decrease the risk of selected malformations when used for a febrile illness. Pages: 48+4 Source: Feldkamp ML, Meyer RE, Krikov S, Botto LD. Obstet Gynecol 2010;115(1):109-15. Printing: 4+2 color n n n Asian Journal of Obs and Gynae Practice, Vol. 1, January-March 2011 Paper: 170/90 GSM Indian Art Paper Frequency: Quarterly Cover Price: ` 300/- Annual subscription ` 1200/-
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- 13. Asian Journal ofDiabetology From the Desk oF Group eDitor-in-chieF The Asian Journal of Diabetology is a Changing Practice Guidelines: A1C prestigious quarterly journal. Dr Vijay Vishwanathan, an eminent Diabetologist, Managing Director, MV Hospital for Diabetes and Diabetes Research Center, Chennai is the Editor of the journal. Dr KK Aggarwal Padma Shri and Dr BC Roy Awardee Sr Physician and Cardiologist, Moolchand Medcity The journal focuses on informing Physicians and Diabetologists about President, Heart Care Foundation of India Group Editor-in-Chief, IJCP Group Editor-in-Chief, eMedinewS Member, Delhi Medical Council Director, IMA AKN Sinha Institute (08-09) Hony. Finance Secretary, IMA (07-08) managing various aspects of diabetes Chairman, IMA AMS (06-07) President, Delhi Medical Association (05-06) drkk@ijcp.com to provide better patient care to India’s continually rising population of T diabetics. he American Diabetes Association (ADA), the International Diabetes Federation (IDF) and the European Association for the Study of Diabetes (EASD) have joined forces to recommend the use of the hemoglobin A1C assay for the diagnosis of diabetes. A1C values vary less than FPG (fasting plasma glucose) values and the assay for A1C has technical advantages compared with the glucose assay. A1C gives a picture of the average blood glucose level over the preceding Specifications 2-3 months. A1C has numerous advantages over plasma glucose measurement: It is a more stable chemical moiety. The patient does not need to fast. Readership: 5,000 Measuring A1C is more convenient and easier for patients who will no longer be required to undergo a fasting or oral glucose tolerance test (OGTT). It correlated tightly with the risk of developing retinopathy. Size: A4 The committee has determined that an A1C value of 6.5% or greater should be used for the diagnosis of diabetes. This cut-point, is where risk of retinopathy really starts to go up. Avoid using estimated average glucose, or EAG, as this is just a way to convert the A1C into glucose levels. Source: American Diabetes Association (ADA) 69th Scientific Sessions. Presented June 5, 2009. Diabetes Care Published online June 5, 2009. Pages: 36+4 Printing: 4+2 color Paper: 170/90 GSM Indian Art Paper Asian Journal of Diabetology, Vol. 12, No. 1, January-March 2010 Frequency: Quarterly Cover Price: ` 300/- Annual Subscription ` 1200/-
- 14. Journal Volume 6, Number 3 July-September 2010 Sedation Practices for the Patient in the ICU Should C-reactive Protein Concentration at ICU Discharge be Used as a Prognostic Marker? Clostridium Difficile: Moving Beyond Antimicrobial Therapy ICU Intubation Success Hampered by Non-ideal Conditions: Based on Small Cohort Study... Pain Not Minimized after Minimally Invasive Cardiac Surgery Still Asleep at the (Ventilator) Switch? Timing of Tracheotomy Linked to Length of Stay: Study Finds to Effect on Mortality from Early Procedure more...
- 15. Asian Journal ofCritical Care From the desk oF Group editor-in-chieF Today, the demands on the intensivists Nonresolving Pneumonia are tremendous, making it necessary for them to be updated with the latest in the field. In view of this, IJCP has another specialty journal, Asian Journal of Critical Care. It discusses original research, review articles, Dr. KK Aggarwal Dr BC Roy Awardee technology in medicine for physicians Sr Physician and Cardiologist Moolchand Medcity President, Heart Care Foundation of India Group Editor-in-Chief, IJCP Group and allied health professionals involved Member, Delhi Medical Council Director, IMA AKN Sinha Institute (08-09) Hony. Finance Secretary, IMA (0�-08) Chairman, IMA AMS (06-0�) in treating the critically ill with the aim President, Delhi Medical Association (05-06) drkk@ijcp.com to improve patient care. S low or incomplete resolution of pneumonia despite treatment is a common clinical problem, estimated to be responsible for approximately 15% of inpatient pulmonary consultations and 8% of bronchoscopies.1 Normal resolution of pneumonia is not easily defined. Patients typically note subjective improvement within Specifications 3-5 days of treatment; more specific clinical criteria for resolution include improvement in fever, cough, crackles, leukocytosis, arterial oxygenation (PaO2) and level of C-reactive protein.2 Most studies on the natural history of pneumonia have focused upon the resolution of chest radiographic Size: A4 abnormalities, with ‘slow resolution’ often being defined as the persistence of radiographic abnormalities for greater than one month in a clinically improved host. The diagnostic evaluation of treatment failure in pneumonia should begin with a careful history, physical Pages: 36+4 examination, and review of the clinical picture. One should first consider whether or not the rate of resolution is within the range of expected norms depending on the patient’s underlying host factors, comorbidities, severity of illness and suspected pathogens. In stable or Printing: 4+2 color slowly improving pneumonia, especially in the presence of comorbidities or host factors which are known to delay Paper: 170/90 GSM Indian Art Paper the resolution of pneumonia, careful observation with or without therapy is warranted for 4-8 weeks.3 When needed, further evaluation should include chest CT to look for sequestered areas of infection or for findings that suggest an alternative diagnosis. When pneumonia fails to resolve or when there is clinical progression, Frequency: Quarterly fiberoptic bronchoscopy should be considered. Readership: 20,000 Asian Journal of Critical Care Vol. 5, No. 4, October-December 2009 Price: ` 300/- Annual Subscription ` 1200/-
- 16. Journal July-September 2010
- 17. Asian Journal ofPaediatric Practice From the desk oF group editor-in-chieF From preventive health care to treatment Smokers in the House, a Risk Factor for of childhood diseases to emergency care Hospitalization of Children with Flu and adolescence – all these subjects and Dr KK Aggarwal many more are covered in the much appreciated and read Asian Journal of Padma Shri and Dr BC Roy National Awardee Sr Physician and Cardiologist, Moolchand Medcity President, Heart Care Foundation of India Group Editor-in-Chief, IJCP Group Paediatric Practice. Editor-in-Chief, eMedinewS Chairman Ethical Committee, Delhi Medical Council Director, IMA AKN Sinha Institute (08-09) Hony. Finance Secretary, IMA (07-08) Chairman, IMA AMS (06-07) President, Delhi Medical Association (05-06) Under the able guidance of Dr Swati emedinews@gmail.com A Bhave, Executive Editor, Association of large retrospective case-control study reported at the annual meeting of the Infectious Diseases Society of America (IDSA) says that having smokers in the house increases the possibility of a young child with flu needing inpatient care. Data from more than 1,300 laboratory-confirmed cases of children with influenza, collected by 10 sites in the CDC’s Emerging Infections Program in 2005-2008 were analyzed to identify risk factors for hospitalization Adolescent Child Care in India (AACCI), associated with laboratory-confirmed influenza. Analysis showed that if more than half of household members were smokers it doubled the chances a child would the journal serves as a practical guide for have a serious case of flu. According to Nila Dharan, MD, of the division of infectious diseases at the NYU School of Medicine in New York City, a family member who had been vaccinated against flu was protective, even if the the continuing education of Pediatricians child was not fully protected by immunizations. The study included 290 children ages six to 59 months (median age 20 months) with serious cases of flu; 1,089 age- and zip code-matched children with the flu who did not need inpatient care during the three influenza seasons acted as controls. The salient observations were as below. and Neonatologists. Age of the mother: if ≤26 years, the odds were doubled. The odds ratio (OR) was 2.1, with a 95% confidence interval (CI) from 1.3 to 3.4. The risk was increased if the child’s vaccinations were not up-to-date. The OR was 1.7, with a 95% CI from 1.1 to 2.7. If more than half of household members smoked, the child’s risk of needing inpatient care was doubled. The OR Specifications was 2.3, with a 95% CI from 1.0 to 5.3. The risk was similar to having any pulmonary condition, including asthma. If the child was not fully vaccinated for the flu, having any household member immunized was protective. The OR was 0.5, with a 95% CI from 0.3 to 0.8. Readership: 20,000 Underlying medical conditions also had an important role; presence of a hematologic or oncologic condition increased the risk by a factor of 12. According to Dr Dharan, other researchers have examined a possible association between exposure to smoking and Size: A4 a child’s risk of needing inpatient care for flu, but this is the largest study to date. n n n Pages: 36+4 Printing: 4+2 color Asian Journal of Paediatric Practice, Vol. 14, No. 1 Paper: 170/90 GSM Indian Art Paper Frequency: Quarterly Price: ` 300/- Annual Subscription ` 1200/-
- 18. Journal October-December 2010
- 19. Asian Journal ofEar, Nose Throat The management of diseases and the from the Desk of group eDitor-in-chief New Daily Persistent Headache latest techniques in the subspecialties of Otology, Rhinology and Laryngology need to be discussed and informed at length under a common platform efficiently provided by the Asian Journal of Ear, Dr KK Aggarwal Nose Throat. Padma Shri and Dr BC Roy Awardee It provides worldclass information to Sr Physician and Cardiologist Moolchand Medcity President, Heart Care Foundation of India Group Editor-in-Chief, IJCP Group Chief Editor, eMedinewS Member, Delhi Medical Council Director, IMA AKN Sinha Institute (08-09) Hony. Finance Secretary, IMA (07-08) Indian ENT practitioners under the guidance of its founder Editor, Dr VP Sood, Chairman, IMA AMS (06-07) President, Delhi Medical Association (05-06) drkk@ijcp.com Secretary-cum-Managing Trustee, Dr Sood N Nasal Research Foundation, Past President ew daily persistent headache (NDPH) is a primary headache disorder in which headache begins one day and does not remit, in an individual without a headache history. The pathophysiology is poorly understood. Onset of NDPH can be triggered by certain events, such as infection. The incidence and prevalence of NDPH are unknown, but is rare. It is more frequent in children than in adults, and affects women more often than men. A characteristic feature is that the headache starts abruptly and is Association of Otorhinolaryngologists. daily and unremitting from, or almost from, the moment of onset, typically in individuals without a prior headache history. Specifications The diagnosis is clinical and requires ruling out secondary causes. Current diagnostic criteria exclude patients with predominant migrainous features, many headache experts contend that the diagnosis of NDPH can be made regardless of the presence of migrainous features. For patients with recent onset of suspected NDPH, one should do neuroimaging upon presentation. A lumbar puncture is indicated if clinical features suggest a possible central nervous system infection or idiopathic intracranial hypertension. Readership: 20,000 The differential diagnosis includes a number of secondary and primary causes of headache. It is particularly important to consider cerebral venous sinus thrombosis, headache secondary to spontaneous cerebrospinal fluid leaks, idiopathic intracranial hypertension (pseudotumor cerebri), and giant cell arteritis. NDPH may take either of two subtypes: a self-limited one, or a persistent form which can last years or decades and is challenging to treat. Size: A4 For patients with primary NDPH, first classify the phenotype of NDPH as most similar to either migraine or tension-type headache, and then treating with appropriate preventive headache therapy accordingly. n n n Pages: 36+4 Asian Journal of Ear, Nose Throat, April-June 2010 Printing: 4+2 color Paper: 170/90 GSM Indian Art Paper Frequency: Quarterly Price: ` 300/- Annual Subscription ` 1200/-
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- 21. Indian Journal ofMedilaw From thE dEsk oF group Editor-in-ChiEF There has been a considerable increase Editorial Driving Restrictions for Patients with Seizures in medicolegal cases in India in the KK Aggarwal past few years. This rise in medical law litigations is due to Consumer Protection Act (CPA) and awareness about protection of patients’ rights and consistent public Dr KK Aggarwal Padma Shri and Dr BC Roy National Awardee Sr Physician and Cardiologist, Moolchand Medcity demands for professional accountability. It is also a fact that, there are no apparent President, Heart Care Foundation of India Group Editor-in-Chief, IJCP Group Editor-in-Chief, eMedinewS Chairman Ethical Committee, Delhi Medical Council Director, IMA AKN Sinha Institute (08-09) Hony. Finance Secretary, IMA (07-08) and explicit guidelines in this regard. Chairman, IMA AMS (06-07) President, Delhi Medical Association (05-06) emedinews@gmail.com http://twitter.com/DrKKAggarwal Krishan Kumar Aggarwal (Facebook) The Indian Journal of Medilaw was launched with the objective to keep the Indian Doctors updated about the current The seizure-free interval is the most practical and widely used measure of a patient’s driving risk. laws and implications on their practice. Longer seizure-free intervals (6-12 months) are associated with reduced risk of seizure-related motor vehicle accidents (MVA). Shortening seizure-free intervals to three months by some states has not been associated with increased MVAs. High seizure frequency, medical noncompliance, a history of MVAs and other factors increase the risk of seizure-related MVA. These should be considered to extend the seizure-free interval requirement for driving Specifications recommendations. An established pattern of purely nocturnal seizures, consistent and reliable seizure auras, clear provocation, Size: A4 or acute symptomatic seizures in a condition that is not associated with epilepsy or is unlikely to recur may reduce the seizure-free interval requirement. Pages: 36+4 Doctors should also consider other neurologic contraindications for driving in their patients with epilepsy, including impaired cognition and visual field defects. The Epilepsy Foundation is a good resource for the current state specific rules on driving and epilepsy. (www.epilepsyfoundation.org/living/wellness/transportation/driverlicensing.cfm) Doctors should discuss driving with patients and record this discussion in the medical record. This discussion Printing: 4+2 color should include the risk of driving. Indian Journal of Medilaw, September-November 2010 Paper: 170/90 GSM Indian Art Paper Quantity: 2-10,000. Frequency: Quarterly Price: ` 300/- Annual Subscription ` 1200/-
- 22. IJCP International Journals American Family Physician Indian Edition A peer-reviewed journal of the American Academy of Family Physicians November-December, 2006 Diagnosis and Diagnosing Rhinitis: Allergic vs. Nonallergic Treatment of Community- Assessment of Microscopic Hematuria in Acquired Tuberculosis Adults Diagnosis and Treatment of Chlamydia trachomatis Infection Diagnosis and Treatment of Neisseria gonorrhoeae Infections Diagnostic Approach to Pleural Effusion in Adults Hepatitis A Management of Hip Fracture: With Best Compliments from The Family Physician’s Role A Division of Pharmaceuticals Ltd.
- 23. IJCP American FamilyPhysician American Family Physician is the journal Diagnosing Rhinitis:Allergic vs. Nonallergic of the American Academy of Family DAVID M. QUILLEN, M.D., and DAVID B. FELLER, M.D. University of Florida Family Medicine Residency Program, Gainesville, Florida Physicians (AAFP). Allergic rhinitis, the most common type of rhinitis, generally can be differentiated from the numerous types of nonallergic rhinitis through a thorough history and physical examination. Allergic rhinitis may be The American Academy of Family seasonal, perennial, or occupational. The most common cause of nonallergic rhinitis is acute viral infection. Other types of nonallergic rhinitis include vasomotor, hormonal, drug-induced, structural, and occupational (irritant) Physicians is one of the largest national medical organizations, representing more rhinitis, as well as rhinitis medicamentosa and nonallergic rhinitis with eosinophilia syndrome. Since 1998, three large expert panels have made recommendations for the diagnosis of allergic and nonallergic rhinitis. than 94,000 family physicians, family Allergy testing (e.g., percutaneous skin testing, radioallergosorbent testing) is not necessary in all patients but may be useful in ambiguous or complicated cases. (Am Fam Physician 2006;73:1583-90. Copyright medicine residents, and medical students © 2006 American Academy of Family Physicians.) R hinitis is an inflammation of the diagnosis of rhinitis. This report is intended nationwide. Founded in 1947, its mission nasal mucosa. Associated clinical to be a complete evidence-based guideline symptoms include excessive mucus production, congestion, on the diagnosis and management of allergic rhinitis and asthma. The authors proposed has been to preserve and promote the science and art of family medicine and to sneezing paroxysm, watery eyes, and nasal a new classification for allergic rhinitis, and ocular pruritus. The differential arguing that the current subdivisions (i.e., diagnosis of rhinitis is extensive (Table 11). seasonal and perennial) were not Allergic rhinitis is considered a systemic illness and may be associated with satisfactory. Traditionally, pollens and molds were considered possible causes of ensure high-quality, cost-effective health constitutional symptoms such as fatigue, seasonal allergic rhinitis. However, in some malaise, and headache. It also may be a comorbidity in patients with asthma, places, such as California and Florida, these allergens are present year-round. The WHO care for patients of all ages. eczema, or chronic sinusitis. Differentiating authors suggested a classification system allergic rhinitis from other causes of rhinitis based on the symptoms of intermittent, can be difficult because the diagnostic criteria for various forms of rhinitis are not persistent, mild, and moderate-severe rhinitis. IJCP holds the sole printing rights for always clear-cut. Accurate diagnosis is important because therapies that are effective for allergic rhinitis (i.e., The third report2 was coordinated by the Agency for Healthcare Research and Quality (AHRQ) in collaboration with the American Family Physician in India. antihistamines and nasal corticosteroids) American Academy of Family Physicians may be less effective for other types of and the AAAAI. Unlike the first two reports, Specifications rhinitis.2 the AHRQ report is not a clinical guideline Since 1998, three expert panels1-3 have but an evaluation of the evidence on rhinitis. published reviews of rhinitis. The first report1 The report did not identify any studies was created by the American Academy of differentiating allergic rhinitis and Allergy, Asthma, and Immunology (AAAAI) nonallergic rhinitis based on clinical as a complete guideline for the diagnosis and symptoms, physical examination findings, management of rhinitis. The second report,3 coordinated by the or associated comorbidities. The AHRQ report noted that the treatment conclusions Size - A4 World Health Organization (WHO), focuses may have been biased because Pages - 36+4 on allergic rhinitis and asthma but includes pharmaceutical companies supported many an extensive section on the differential of the trials.2 Printing - 4+2 printing 8 American Family Physician (Indian Edition) Volume 1, Number 4 October-December, 2006 Paper- 170/90 GSM Indian Art Paper Frequency: Quarterly Binding: Center Stitch
- 24. Publishing Article ina Journal Publishing Articles in a Journal A scientific article, 4-6 pages long, can be published in any of our journals @ Rs 200,000/- per article inclusive of compilation, editing, layouting and Special Reprint 2009 printing subject to peer review/approval Methylcobalamin, Pyridoxine and Nicotinamide in by the Editorial Board. Diabetic Neuropathy: A Review S Jayaram*, Akash Khobragade**, Deepak Langade† ABstRAct Diabetes is the most common etiological factor for peripheral neuropathy (PN). While conventional theory says that prolonged hyperglycemia results in the complications associated with diabetes, including neuropathy, a recent study found that PN can manifest even in individuals with abnormal Journal Article Reprints glucose tolerance, a prediabetic condition. A combination of methylcobalamin, pyridoxine and nicotinamide thus has additive and synergistic effects on the damaged nerve in diabetic neuropathy which protect the nerve from further damage, restore its structural and functional integrity and cause a recovery of function. Key words: Hyperglycemia, prediabetic, polyneuropathy, adenosylcobalamin, vitamin B6, nicotinic acid, Specifications myelin sheath, axon Background incidence approaches 50% for patients with diabetes Peripheral neuropathy (PN) is characterized by pain, for more than 25 years.1 A study conducted in South numbness and tingling in the extremities and slow India to find the prevalence and risk factors, found nerve conduction. It affects a significant percentage a PN prevalence of 19.1% among type 2 diabetics of the Indian population and can be extremely debilitating. Around 7% of patients usually have attending the diabetic clinic. Neuropathy was diagnosed if the vibratory threshold of the great toe exceeded 25. The incidence of PN increases with Size: A4 neuropathy upon diagnosis of diabetes, and the increase in age and duration of diabetes.2 Based on a *Hon. Professor of Medicine compilation of studies from different parts of the world, the World Health Organization (WHO) has projected Paper: 110 GSM Indian Art Paper Bombay Hospital, Mumbai that the maximum increase in diabetes would occur in **Resident India.3 Considering the large population and the high † Clinical Pharmacology, Ex-lecturer Dept. of Pharmacology Grant Medical College and Sir JJ Group of Hospitals prevalence of diabetes, the burden of diabetes and it’s complications in India would become enormous. Printing: 4 + 2 color offset printing Mumbai Pathophysiology of diabetic neuropathy Pages: 4/6/8 pages Address for correspondence Dr Deepak Langade Diabetes is the most common etiological factor for PN 503/E-7, Runwal Estate, Opp. Lawkim and it is also the most studied in terms of pathogenesis. Ghodbunder Road, Thane (W), Mumbai - 400 607 While conventional theory says that prolonged E-mail: drdgl@hotmail.com hyperglycemia results in the complications associated June 2009 INDIAN JOURNAL OF CLINICAL PRACTICE l VOL. 20, NO. 1 One full page Advertisement
- 25. Advertisement Tariff (CodeA 20) Position Dimension Amount Cover Double Spread 24.5 × 39.5 ` 200,000 Gate Fold False Cover 24.5 X 17.5 ` 150,000 Front page strip 19.5 X 5.0 ` 150,000 Inside Front Cover 24.5 X 17.5 ` 100,000 Front Solus Quarter 14.5 X 11.0 ` 100,000 Back Cover 24.5 X 17.5 ` 1, 50,000 Inside Back Cover 24.5 X 17.5 ` 100,000 Full Page 4 Color 24.5 X 17.5 ` 40,000 Half page 4 Color 12.25 X 17.5 ` 25,000 Full Page 2 Color 24.5 X 17.5 ` 30,000 Half Page 2 Color 12.5 X 17.5 ` 20,000 B/W Full Page 24.5 X 17.5 ` 15,000 B/W Half Page 12.25 X 17.5 ` 12,000 Utility Corner 4 Color Quarter 7.0 X 5.0 ` 50,000
- 26. IJCP Health InformationProducts
- 27. Dr. Good Dr.Bad Dr Good Dr Bad is a copyrighted cartoon based product of IJCP, which depicts a clinical situation that a doctor might Situation : A 30-year-old female with a diabetic mother came for come across and the correct way to deal a check-up. with it, in the form of caricatures. The clinical lesson is supported by a scientific reference. You cannot You are also at risk of heart disease be at risk A Ready Reckoner, which a doctor may refer to, when he encounters a clinical situation that may be difficult to handle. Specifications © IJCP GROUP LeSSon : As per results of the Fremantle Diabetes Study, a maternal family history of diabetes confers relative protection against Size: 4.0 x 5.5 inches or 8”x5.5” inches cardiovascular disease in female patients but not in male patients with type 2 diabetes. Paternal family history is associated with risks equivalent to those without a family Pages: 20 + 4/ 52+4 history of diabetes. Diabetes Care 2010;33(7):1477-83. Paper: Inside - 90 GSM Maplitho Cover - 250 GSM Art Card/Hardbound Dr. KK Aggarwal Printing: 4+2 Color Binding: Centre stitch/Hardbound/Perfect binding
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- 29. Handbooks ECG F ormulaE IJCP’s Handbooks are a highly coveted academic gifts for doctors. Covering Indications of ECG The main indications are for the evaluation of various topics of relevance to clinicians, 1. The electric axis of the heart these Handbooks give a complete insight 2. Heart rate monitoring 3. Arrhythmias on the subject discussed therein. a. Supra ventricular arrhythmias b. Ventricular arrhythmias An ideal companion to doctors, Handbooks c. Disorders in the activation sequence- AV conduction defects have a long shelf life. d. Bundle-branch block e. Wolff-Parkinson-White syndrome 4. Increase in wall thickness or size of the atria and ventricles a) Atrial enlargement (hypertrophy) b) Ventricular enlargement (hypertrophy) 5. Myocardial ischemia and infarction a. Ischemia b . Infarction 6. Drug effect a Digitalis b. Quinidine Specifications 7. Electrolyte imbalance a. Potassium b. Calcium Size: 7 x 4.5 inches 8. Carditis a. Pericarditis Pages: 32-56 +4 pages b. Myocarditis 9. Pacemaker monitoring Paper: 210/90 GSM Indian Art Paper Printing: 4+2 color offset printing Binding: Centre stitch/ perfect binding
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- 31. Organ Failure Score Organ system Criteria for failure Liver Clinically acute liver failure Hematological WBC count ≤1,000 per µl Platelet count ≤20,000 per µl Hematocrit ≤20% and not chronic renal failure Neurological Glasgow coma score ≤6, in absence of sedation, at any one point in day Respiratory Respiratory rate ≤ per minute, or ≥49 per minute PaCO2 0 mmHg Dependent on ventilator on 4th day of organ system failure (do not apply for first 72 hours of organ system failure) Cardiovascular Heart rate ≤4 bpm Mean arterial blood pressure ≤49 mmHg Occurrence of ventricular tachycardia and/or ventricular fibrillation Serum pH ≤7.24 with PaCO2 ≤49 mmHg Renal Urine output ≤479 ml/day, or ≤19 ml during an 8-hour period and serum urea ≥214 mg/dl Urine output ≤479 ml/day, or ≤19 ml during an 8-hour period and serum creatinine ≥3. mg/dl Mean arterial blood pressure = [(systolic BP) + (2 × (diastolic BP)]/3 Suggested Readings 1. Chang RW, Jacobs S, Lee B. Predicting outcome among intensive care unit patients using computerised trend analysis of daily Apache II scores corrected for organ system failure. Intensive Care Med 1988;14:8-66. 2. Garden OJ, Motyl H, Gilmour WH, et al. Prediction of outcome following acute variceal hemorrhage. Br J Surg 198;72:91-. 3. Thomson JN. Laboratory control of anticoagulant therapy. In: Blood Coagulation and Haemostasis, 2nd edition, Thomson JN, (Ed.). Chapter 9. Churchill-Livingstone 1980:279-329. doctor. bound a daily basis. Specifications Laminated Cover Printing - 4+2 Color Pages - 12-16 + 4 pages Size - A 4 (8 X 11 inches) Paper - 210/110 GSM Indian Art Paper ‘Algorithms’ are a much in demand Algorithms come most handy when a decision trees and furnish step-by-step academic gifts for doctors, which contain clinician confronts a clinical situation on disease management guidelines to a Algorithms Binding - Center Stitch/perfect binding/Hard
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- 33. 100 Cases Series 100Interesting Cases in Dentistry Volume 2 100 Case Series is a highly prized academic Case 8 gift for doctors and is of great clinical Keep it Simple Sir importance. The series contains unusual Subhashini S, US Krishna Nayak Mangalore and interesting cases reported by eminent clinicians they have come across in their W hatever we do in our day-to-day life should be simple and sweet including Treatment Plan our treatment mechanics. What is more important for a successful treatment result is • • PEA Mechanotherapy MBT prescription Alignment of arches practice. an accurate diagnosis and prompt treatment • Expansion of upper arch plan. We, herein, describe a case of class III malocclusion. Among malocclusions, Class III is one of the most difficult anomalies • Proximal slenderization and retraction of lower anteriors These Case Series have become to understand and correct as it has strong hereditary components. Functional influences play secondary or adaptive roles. Accurate Cephalometric values SNA Pre treatment 78º synonymous with IJCP due to the large diagnosis and treatment plan has resulted in number of topics published. SNB 81º a pleasing profile in the following case. ANB 3º A 20-year-old woman presented with chief Angle of convexity –7º complaint of irregularly placed front teeth. FMA (Tweed’s) 24º Clinical Examination SN-GoGn Nasolabial angle 30º 98º These Case Series are published as a set • Mesocephalic, mesoprosopic • • Concave facial profile Competent lips of 4 Volumes of 25 cases each. • Anterior crossbite • lingually placed canine 33 • Class I molar relationship Diagnosis Specifications • Class III skeletal base with horizontal growth pattern Pretreatment. • • Angle’s Class I molar Class III canine and incisor relationship Size: 9 x 7 inches • Concave facial profile Treatment Pages: 72 + 4 Objectives • Alignment of upper and lower arch • Correction of overjet and overbite Paper: 80 GSM Indian Art Paper / Cover • Correction of canine and incisor relationship • Achieve optimal facial esthetics Mid-treatment. 310 GSM Art Card/ Hardbound 34 Printing: 4 + 1 or 4 + 2 or 4 color Binding: Paper back/ hardbound format.
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- 35. 100 Question Series The 100 Question Series is a guide to Eo C d int toern t’ s D e s k s the management of common clinical From the Desk of Group Editor-in-Chief situations in a Question and Answer format. All the answers to common but Dr KK Aggarwal Dr BC Roy Awardee Sr Physician and Cardiologist, Moolchand Medcity relevant questions are answered by top President, Heart Care Foundation of India Group Editor-in-Chief, IJCP Group drkk@ijcp.com medical experts. The book is edited by a Diabetes mellitus: the Indian scenario renowned expert in that field. Diabetes mellitus is a major health problem that causes significant mortality and morbidity. It has emerged as a major threat to human health in the 21st century. But predictions for future increases in prevalence, especially in developing countries, foretell a major healthcare crisis for the The Question Series are published as a set future.1 India, in particular, is in the grip of a diabetic epidemic with the highest number of diabetics in the world. According to WHO, 32 million people had diabetes in the year 2000, a number that of 4 volumes of 25 questions each. is projected to increase to 300 million by the year 2025, giving India the dubious distinction of becoming the ‘Diabetes Capital’ of the world.2,3 The International Diabetes Federation (IDF) has projected the number of diabetics in India to increase from 40.9 million to 69.9 million by 2025.4 Also, there is an equally large population with impaired glucose tolerance (IGT), which is a forerunner of diabetes, especially among the young.5 With the Indian diabetic population predicted to rise to 80.9 million by 2030, the long-term economic implications are worrying for the nation.1 Diabetes is no longer a disease of the affluent. Environmental factors related to urbanization have played a significant role in the escalating prevalence of diabetes.5 Changes in dietary pattern coupled with decreased physical activity are the major factors implicated.4 Although there is an increase in prevalence of type 1 diabetes also, it is type 2 diabetes that accounts for 90% of all cases.4 The ‘Asian Indian Phenotype’ refers to some unique clinical and biochemical abnormalities in Indians viz. increased insulin resistance, greater abdominal adiposity i.e. higher waist circumference despite lower BMI, lower adiponectin and higher hs-CRP levels, which makes Asian Indians more prone to develop diabetes and cardiovascular disease.4 In a rather disturbing development, the Specifications CURES6 reported a temporal shift in the age at diagnosis to a younger group compared to the NUDS study.7 Diabetes can be prevented or delayed through lifestyle interventions.8 Hence, there is an urgent need to identify high-risk individuals and implement preventive measures to prevent, or at least Size: 7 x 9.5 inches or 8.5 x 6.25 inches delay the onset of diabetes and thus reduce the disease burden and its sequelae. References 1. Bjork S, et al. Health Policy 2003;66(1):61-72. Pages: 72 + 8 (jacket optional) 2. Wild S, et al. Diabetes Care 2004;27:1047-53. 3. 4. 5. Pradeepa R, et al. Indian J Med Res 2002;116:121-32. Mohan V, et al. Indian J Med Res 2007;125:217-30. Ramachandran A, et al. Curr Sci 2002;83(12):1471-6. Paper: 300/ 80 GSM Indian Art Paper 6. Mohan V, et al. Diabetologia 2006;49:1175-8. Binding: hardbound or perfect binding 7. Ramachandran A, et al. Diabetologia 2001;44:1094-101. 8. Rao SS, et al. Am Fam Physician 2004;69:1961-8,1971-2. (v) Printing: 4 + 1 or 2 or 4 color
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- 37. Make sure Make Sure is a popular cartoon-based copyrighted product from IJCP which highlights certain key points which a Make Sure... doctor must adhere to and follow. Clinical situations and lessons are illustrated with caricatures for easy recollection. A patient of TB taking ATT complains of numbness in fingers and toes. This booklet is a highly prized academic gift for doctors. A ready reckoner for Make Sure... Oh My God! ! Forget To Prescribe clinicians. Vitamin B Complex Specifications Make sure That in patients taking ATT (including INH) B-complex vita- mins (especially) vitamin B6) are Size: 4.5 x 5.5 inches prescribed to prevent neuro- pathy. Addition of antioxi-dants and multivitamins also boosts Pages: 20 + 4 the immune system. Dr. KK Aggarwal Paper: 170/ 90 GSM Maplitho paper 24 Printing: 4 + 2 color Binding: Center Stitch / Perfect Binding.
- 38. Text Books includingYear Books Supported by IJCP Thromboembolic Disorders
- 39. Text Books includingYear Books Textbooks from IJCP Group are an exceedingly valuable academic gifts for doctors. The Editors and Contributors of Goals of Section 1 the textbook are very scrupulously chosen Communication in Healthcare to uphold the quality that we maintain in all our inputs. Introduction These Textbooks serve as a ready reckoner and are a value-addition to the doctor’s It was a case of retinitis pigmentosa. Dr V knew that his 25-year- old patient, a young woman, was going to lose her eyesight in the shelf. left eye, permanently. But the young age of the patient, the fact that the disease had progressed pretty far by now, had him in a bind. Her lower middle class family depended on her livelihood completely and he didn’t want to upset them further. He did not explain the disease, either to the patient or the family. The operation did not help. This added to his discomfort and he found himself unable to be supportive to the family. The family read this as guilt on his part and pressed charges of medical negligence. T he reasons for augmenting communication skills for a medical practitioner cannot be further underlined. As people walk into a medical clinic with their symptoms, some overt, some hidden, unknown even to themselves, communicating rightly is a challenge to every doctor’s practice. It is essential for Specifications dispensing high quality medicine, improving patient satisfaction, helping in recall and outcomes of healthcare. In today’s competitive environment, satisfied patients alone can determine if you gain success as a private practitioner. The Iris Pupil Sclera Size: 7.2 x 9.8 inches or 8.5 x 6.25 inches fact that patients don’t complain doesn’t necessarily mean they Vitreous Pages: 180 + 8 are satisfied with the care they’re receiving, the staff members with whom they interact and the office in general. Research shows that only 4% of the dissatisfied patients even Lens Printing: 4+1/2 Color bother to complain, atleast to the person who either caused or could Retina Skill EnhancEmEnt for mEdical StudEntS: communication for SuccESS 13 Binding: Hard Bound / Perfect Binding Paper: 310/80 GSM Indian Art Paper
- 40. s Me Lord Me lord Answering Medicolegal Questions
- 41. Me Lord Recent years have seen a spurt in the Me lord: Answering Medicolegal Questions medicolegal cases in India in the past few Q: Is the enquiry being done by the full court or a quasi judicial body? years. Most doctors remain unaware of Quasi judicial body is an individual body or organization which has powers resembling those of courts of law or judge and is able their legal positions and their rights. to remedy a situation or impose legal penalties on a person or organization. ME LORD is the latest book from IJCP State Medical Councils and Medical Council of India are examples. In one of the judgments Delhi Medical Council observed “the council took note of those irregularities in respect of police report that answers several common medicolegal and observed that this misrepresentation of facts were not only unprofessional but a vain attempt to mislead a quasi judicial queries authority. These observations regarding misconduct of police need DMC/F.14/DC/ to be brought to the notice of the higher authorities in the police Comp/2007/dated department so that corrective measures are initiated.” 1.11.2007) DMC Act Section 21 (5) clarifies further: “In holding an inquiry under this section, the council and the executive committee, as the case may be, shall have the similar powers as are vested in civil courts under the Code of Civil Procedure 1908 when trying a suits in respect of following matters, namely: (a) Enforcing the attendance of a person and examination (b) Compelling the production of documents (c) Issuing of memos for the examination of witnesses” Specifications Section 21 (6) DMC at further elaborates “All the enquires under this section shall be deemed to be judicial proceedings within the DMC Act 21(5,6) meaning of section 193, 219, 228 of the IPC (45/1860)”. Size: 8.5 x 5.5 inches Pages: 178 + 4 Printing: 4+2 color Paper: 170/80 GSM Indian Art Paper Binding: Perfect Binding.
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- 43. IJCP Drug Books Drug Books spotlight the various drug Cefixime classes used in day-to-day practice and Cefixime contain information about various aspects Adverse Reactions of drugs viz. Drug-drug interactions, 1. Gastrointestinal: • Diarrhea Adverse effects etc. • Abdominal pain • Nausea These Drug Books can be developed based • Dyspepsia on drugs used in different specialties. • Flatulence • Loose stools 2. Renal Tocxity: Acute renal failure 3. CNS: • Sezial • Headache 4. Cardiovascular: • ECG change PT intervalprologed 5. Systemic effect: • Estrogensan syndrome • Toxic epromonolacratite • Seram sickness Contraindications: • Hypersensitivity to cefixime (Cefalogroup) • Lactation Specifications CefAdRoxil Adverse Reactions 1. Gastrointestinal: Size: 8 x 5.5 inches • Diarrhea • Abdominal pain Pages: 132 + 4 • Angioedema • Cholestasis Printing: 4+1 or 4+2 color • dyspepsia • nausea Paper: 210/80 GSM Indian Art Paper Binding: Perfect Binding
- 44. Prescription (or Tearoff) Pads Know About PCOS What is PCOS? Polycystic ovarian syndrome (PCOS) is a fairly common condition which affects 5-10 percent of women in childbearing age. What are the symptoms of PCOS? The symptoms of PCOS include irregular menstrual periods, excess facial hair growth, acne and obesity. What is the reason for infrequent or absent menstrual periods in PCOS patients? Infrequent or no production of progesterone causes infrequent or absent menstrual periods in PCOS patients. What are the chances of a PCOS women being infertile? PCOS is a common cause of female infertility because of chronic anovulation/menstrual irregularity. What are the tests needed for diagnosis of PCOS? In addition to proper family/menstrual history, ultra- sonography helps in diagnosing PCOS. Most PCOS women have slightly enlarged ovaries surrounded by a number of small cysts that can be seen in an ultra- sound examination. From the Makers of
- 45. Prescription (or Tearoff) Pads Prescription (or Tear off) Pads are a value added uniquely presented academic gift “Once a certain rapport is established with the patient, the doctor could be less formal with with illustrations of information required him and work towards being viewed as a friend and by a doctor in his clinic to pass on to his confidante” patients. These specially designed prescription pads create a very high impact and also serve to educate patients. Specifications Size: 7 x 9 or 4.5 x 9 inches Printing: 4+1 color Pages: 52 + 4 Paper: 80 GSM Indian Art Paper Binding: Perforated and Tear off Facility
- 46. Annual Diary withScientific Inputs 20 08
- 47. Annual Diary withScientific Inputs Annual Diaries contain about 40 1 Su Mo Tu We Th Fr Sa January 2006 1 8 15 2 9 16 3 10 17 4 11 18 5 12 19 6 13 20 7 j 14 21 a pages of scientific inputs that include 28 n decision trees and clinical tips 22 23 24 25 26 27 29 30 31 sunday among other relevant information. One Clinical Tip (Supported with reference)/Quote is incorporated on bottom of every page apart from the 40- page clinical material at the beginning of the Diary. January 2006 Monday 2 Specifications Size: A4 Pages: 240 Printing: 4 + 2 or 4 + 1 color Xylometazoline hydrochloride is an imidazoline derivative commonly used in topical application to relieve nasal congestion associated with acute or chronic rhinitis, Paper: 90 GSM Hard Bound Super common cold, sinusitis and hay fever or other allergies. Drugs Exp. Clin. Res. 2005;28(1):27-35. Indian Art Paper and Includes 6 Pages Advertisement
- 48. IJCP Posters Posters make an ideal companion to the doctor at his clinic. Designed in a patient-friendly format and supported by suitable and attractive illustrations, these Posters serve as educative tools for the patient. Specifications Size: 16 x 22 inches Page: Single Page Printing: 4 Color Lamination with Two Sided Back Gumming Paper: 210 GSM Indian Art Paper.
- 49. Patient Educational Leaflets GUM(Periodontal Disease) Signs and symptoms of periodontal (or gum) disease? Stages of PerioDontal (or gum) disease Gingivitis 1 Patient Education Leaflets are an Healt hy Gum educational tool for the patient. They Bleeding Periodontal When infection Redness in gum Gum Supporting tisue disease or involves only the Swollen gum Red, swollen and painful No bone loss gum disease is gums (gingivae), it is Teeth gums inform the patient about a disease infection of the called gingivitis. gums and the Unhe althy Gum tissues supporting 2 Periodontitis condition/procedure and thus help the teeth. Bleeding while brushing or Infection spreading to bone and tisues Gum infection Gum Infection Gum flossing Gums receding from spreads to bone and the teeth Teeth Deeply infected bones tissues that support the teeth. Causes of Periodental Disease (or Gum) Teeth that are sensitive to heat and/or cold Advanced periodontitis Pockets become deep 3 to secure informed consent, patient and may fill with pus. cooperation, and a high level of patient As more gum tissue The pockets Norm al Tooth become deep Normal Tooth and bone are destroyed, Pus formation No visible teeth become loose and Bones and Tisues more compliance. These Leaflets may translated deposits Gums pulling away from may fall out or may have destroyed the teeth making teeth to be removed. Plaqu e appear longer treatment Plaque is the film of bacteria that is formed on the teeth and gums and difficult to see. Cleaning of deposits in the gum line Smoothen rough surfaces on tooth into regional Indian languages. Plaque Pus between Loose Space Tarta r teeth and teeth between teeth If the Plaque is not gums removed it will harden into Gargle or Rinse 3-4 times a day a thick yellow or brown Consult a PerioDontiSt with the antiseptic mouthwash Tartar like Betadine Gargle * if you notice any of In more severe gum disease, you may be prescribed medications these symptoms. like antibiotics to control germs that cause infection OR surgery may be required. Tips to prevent periodontal (or gum) disease Brush your teeth twice a day Specifications Visit your dentist regularly, at least twice a year Eat a balanced diet containing plenty of fresh fruits and Size: A4 vegetables Clean between your teeth every day with flass Page; Single Control your blood sugar Limit intake of sodas, coffee and alcohol Paper: 80 GSM Indian Art Paper Stop smoking Advt. Printing: 4 Color Offset Printing Reduce both the quantity and frequency of sugar intake Back to Back Printing Use a mouthwash like Betadine Binding: 2 Folds Published, Printed and Edited by Dr KK Aggarwal, on behalf of IJCP Academy of Gargle and toothpast as CME as part of their social commitment towards upgrading the knowledge of Indian Also Available with Dockets recommended by your dentist doctors. Published at: Daryacha, 39 Hauz Khas Village, New Delhi - 110 016. Telefax: 26965874/75; E-mail: editorial@ijcp.com, drkk@ijcp.com Website: www.ijcpgroup.com, HIP/IN/----
- 50. IJCP Playing Cards Playing Cards are an unique gift from IJCP. Each card, in the 52 pack, contains a illustrated one-liner health/ scientific message. Specifications Size: 3.5 x 2.25 inches Paper: 250 GSM Indian Art Paper Printing: 4 Color Offset Printing and A Cover Pack
- 51. Interactive Games Snakes andLadder, Worms and Ladder, Ludo, Chess, Dart etc are unique educational tools. These contain Health Messages/ Do’s and Dont’s and Educational Tips. Specifications Size - 11 x 16 inches (16 x 16 inches Double Fold for Ludo) Pages - single page Paper - 210 GSM Indian Art Paper Printing - 4 Color Offset Printing with Lamination
- 52. T Table Tops S M T W T F S S M T W T F S January January 1 2 JAN 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 2005 2005 SATURDAY SUNDAY Things to do today
- 53. May S M T W T F S S M TWT F S M 1 2 3 4 5 6 7 8 9 10 11 12 13 14 May A 15 16 17 18 19 20 21 22 23 24 25 26 27 28 7 Y 29 30 31 8 2005 2005 SATURDAY Things to do today SUNDAY Aluminium and magnesium hydroxide have a remarkable tolerability and clinical efficacy profile for relieving acidity. Cleve. Clin. J. Med. 2003 Nov.;70(Suppl. 5):S51-S70. Specifications Size: A 5 or A4 Binding: Spiral Binding Stand: 28 Ounce Mill Board Paper: 110 GSM Indian Art Paper Product with Intermediate Shelf Value clinical and educational information. contain a Calendar/Planner and useful Table Tops are academic gifts, which Table Tops
- 54. Newsletters AN IJCP PUBLICATION GROUP www.ijcpgroup.com October-December 2010 Pages 8 Volume 3, Number 4 SEXUAL HEALTH From the Desk of Group Editor-in-Chief ...... In This Issue Dr KK Aggarwal multiple sclerosis, and atherosclerosis); smoking; Padma Shri Dr BC Roy National Awardee being overweight; and certain medications. About Pages Sr Physician and Cardiologist, Moolchand Medcity President, Heart Care Foundation of India 8 of the 12 most commonly prescribed medications issue Group Editor-in-Chief, IJCP Group Herbs .................2 Editor-in-Chief, eMedinewS list impotence as a side effect and about 25% of Chairman Ethical Committee, Delhi Medical Council the ED cases are due to medications. Examples Director, IMA AKN Sinha Institute (08-09) Hony. Finance Secretary, IMA (07-08) of medications that disrupt normal male sexual Interview Chairman, IMA AMS (06-07) function include most antidepressants (in President, Delhi Medical Association (05-06) Dr DM Mahajan .................3 emedinews@gmail.com particular, selective serotonin reuptake inhibitors), https//twitter.com/DrKKAggarwal Krishan Kumar Aggarwal (Facebook) spironolactone, sympathetic blockers (such as clonidine, guanethidine, or methyldopa), thiazide Do Beta-Blockers Cause diuretics, ketoconazole, cimetidine, and beta- Sexual Dysfunction? .................3 E rectile dysfunction (ED), one of the most prominent complaints concerning sexual activity among men, is defined as the recurrent or persistent blockers. Several studies have shown that most cases of ED Assessing and Managing recognize a vascular etiology and are associated this Sexual Problems in Men .................4 inability to attain and/or maintain an erection with hypertension and diabetes. Other studies have sufficient for satisfactory sexual activity. It has reported high prevalence of ED in patients with been reported to affect as many as 152 million men coronary artery disease. Therefore, an underlying Clinical Performance of Tentex worldwide. Although ED is usually considered a vascular disease is the cause of ED in several men. Royal in Erectile Dysfunction .................4 benign disorder, it may have a major impact on the Also, men who present with ED may be at a higher quality of life of not only the affected men, but also risk for subsequent development of cardiovascular their sexual partners. Interview events. Patients with ED without an obvious cause Dr Prakash Kothari .................5 Experts believe that psychological factors such as (eg, pelvic trauma), and who have no symptoms stress, anxiety, guilt, depression, low self-esteem, of coronary or other vascular disease, should be In and fear of sexual failure cause 10% to 20% of ED screened for cardiovascular disease prior to initiating Male Sexual Health in cases. Other possible causes include damage to the therapy for their sexual dysfunction, as there are Ayurveda .................6 nerves, arteries, smooth muscles, and fibrous tissues; potential cardiac risks associated with sexual activity diseases (such as diabetes, chronic alcoholism, in patients with heart disease. Time to Laugh .................7 Clues to the Diagnosis of Erectile Dysfunction Clinical clue Suggested diagnosis History Altered or impaired partner sexual function Psychological causes (eg, anxiety, depression, guilt, history of sexual abuse, marital or relationship problems, stress) Decreased volume of ejaculate Chronic prostatitis, normal aging process, obstruction of ejaculatory duct(s), retrograde ejaculation Decreased libido Chronic fatigue syndrome, hypogonadism, hypothyroidism, psychological conditions Impaired quality and timing of orgasm, Alcohol abuse, Cushing syndrome, hyper- or hypothyroidism, including anorgasmia medications (eg, antihistamines, antipsychotics, β-blockers, selective serotonin reuptake inhibitors, thiazides, tricyclic antidepressants), psychological causes, surgery of the pelvis or prostate Presence of sexually induced genital pain History of sexual abuse, genital piercings, sexually transmitted infections (eg, genital herpes) “The best things in life are free. The rest are married”. Physical examination Assessment of body habitus for central obesity Cushing syndrome, diabetes mellitus, metabolic syndrome Decreased perineal sensation Cauda equina syndrome, spinal stenosis, surgery of the pelvis or prostate, trauma Decreased peripheral pulses Atherosclerotic and peripheral vascular disease Elevated blood pressure Atherosclerotic vascular disease, cerebrovascular disease Enlarged prostate on digital rectal examination Benign prostatic hyperplasia, prostate cancer Penile curvature Peyronie disease, ruptured corpora cavernosum, venous leakage Tachycardia Anxiety, hyperthyroidism, stimulant abuse, underlying cardiovascular disease Testicular abnormalities Epididymitis, hypogonadism, testicular cancer, varicocele Thyroid goiter Hyper- or hypothyroidism Source: Heidelbaugh JJ. Am Fam Physician. 2010;81(3):305-312. This issue sponsored by: Stadmed Stadmed www.stadmed.co.in Series-1 Role of Lysine in Management of Iron Deficiency Anaemia I ron deficiency anaemia (IDA) is the most prevalent nutritional deficiency worldwide and is an important health problem.1 About two billion people are affected It reverses the effect of dietary inhibitors and is one of the most powerful known promoters of nonheme iron absorption.5 Ascorbic acid forms a chelate with the iron in It has been suggested that lysine forms a chelate with iron, forming stable globally.2 Deficiencies of other micronutrients e.g. folic food at the acidic pH of stomach that does not dissociate; complexes, which acid that may also cause anaemia often coexist with iron the chelated iron so formed remains soluble at the alkaline keep iron in a soluble deficiency.3 Pregnant women are at particularly high risk pH of the duodenum thereby facilitating iron absorption. state.12 When dietary iron of IDA; in developing countries, the prevalence ranges Being a reducing agent, ascorbic acid prevents oxidation is ingested with phytic acid, from 35-75%.4 The prevalence of IDA in India is 38-72%; and thus maintains iron in the highly soluble ferrous form. bran etc. the formation of an women and children are the major groups affected.5 insoluble precipitate may Experimental studies of preschoolers with anaemia who IDA has considerable health and economic consequences leave iron unavailable for consumed a purely vegetarian diet showed that crystalline and decreases productivity due to reduced work capacity absorption which is simply ascorbic acid (100 g) taken with meals for two months in adults; it affects motor and mental development in eliminated in feces significantly improved hemoglobin (Hb) level that was children and adolescents including poor pregnancy as phytate, oxalate, higher than the increase observed with iron supplements in outcomes such as low birth weight and premature phosphate etc.13 the same study (1.9 g/dl vs l.l g/dl).9 In another study, delivery.1,6,7 When iron demands by the body are not met supplementation of 50 mg vitamin C along with iron/folate Iron intake in the form by iron absorption from the diet, iron deficiency results.1 increased iron absorption to 7.7% than iron/folate of an amino acid chelate In developing countries, the high anaemia incidence is supplementation alone where iron absorption was 1.6% is advantageous. Firstly, attributed to inadequate iron intake. Chronic intestinal only.10 Mehnaz et al showed that vitamin C supplemen- iron absorption as an amino blood losses due to parasitic and malarial infections or tation together with iron/folate increased iron absorption acid chelate is greater than physiologic losses in a woman of reproductive age or and significantly improved hemoglobin status of women iron absorption from salts, hampered absorption further add to the iron deficiency. In with anaemia. The intervention group was divided into as there are less chemical developed countries, IDA is more commonly due to two: subgroup I received iron (200 mg) and folic acid reactions that may interfere with iron absorption; there is insufficient iron intake.2 (0.5 mg) daily; subgroup II was supplemented with iron less formation of insoluble complexes as iron is protected (200 mg), folic acid (0.5 mg) and vitamin C (100 mg) daily. by the amino acid ligand of the chelate and is made Iron absorption electrically neutral by the charge balancing effects of the There are two forms of dietary iron: heme iron, found in The iron/folate supplementation given daily in subgroup I chelating ligands. So, more iron is available for absorption. meat; and nonheme iron, found in plant and dairy foods. significantly changed mean hemoglobin level both at Secondly, absorption of iron amino acid chelate into Nonheme iron makes up the bulk of consumed iron.1 30 days and 100 days, the improvement being 0.94 g/dl mucosal tissues is greater, whereas iron from the salt Bioavailability of nonheme iron requires acid digestion and 2.72 g/dl respectively. In subgroup II, vitamin C along source may or may not be. The greater amount of absorbed that depends on the dietary concentration of enhancers with iron/folate supplementation also led to marked iron is especially important in conditions of iron deficiency such as ascorbate, meat and inhibitors such as calcium, improvement in Hb at 30 days (1.6 g/dl) and 100 days or anaemia. In these cases, more iron is made available for fiber, tea, coffee, wine.1 IDA is prevalent worldwide due to (4.36 g/dl). The control group received no supplementation repletion of iron need.13 the inefficient absorption of nonheme iron that forms the and showed nonsignificant increase in Hb; 0.23 g/dl at bulk of the iron in diet.5 30 days and 0.10 g/dl at 100 days (Table 1). After interventions, at 100 days, the proportion of moderate Management of iron deficiency anaemia The advantage of iron amino acid chelate over other (Hb% 7-10 g%) and severe anaemia (Hb%7 g%) sources of supplemental iron is that its greater Ferrous ascorbate decreased from 72% to 36% and 13% to 10.28%, bioavailability into the mucosal tissue cells results in Supplementation with oral iron is generally the first-line respectively. Major impact of intervention was noted in more iron being quickly and safely delivered to target therapy for patients with IDA. Iron is absorbed in ferrous moderate cases where 52% showed improvement. Forty tissues of the body in times of need. This potentially state and is then reduced by ascorbate in the GI tract. three patients i.e. 24.57% attained normal range of Hb allows for smaller doses of supplemental iron being Ferrous salts are absorbed about three times as well as after the interventions.5 required to achieve physiological results, which can also ferric salts. Gastric acid increases iron absorption by aiding result in fewer gastric complaints and reduce risks of formation of ferrous chelates, both soluble and absorbable.8 Role of lysine in absorption of iron iron toxicity and iron overload. Ferrous ascorbate is a synthetic molecule of ascorbic acid and iron and is indicated in the treatment of IDA. Lysine is an essential amino acid, which has a role in the absorption of iron. Legumes (peanuts, beans, lentils, peas) References Though iron and folic acid supplementation form the are rich sources of lysine. The iron amino acid chelate is 1. Killip S. Am Fam Physician 2007;75:671-8. basis of prevention and treatment of anaemia, addition of an excellent iron source. 2. Carley A. Pediatr Nurs 2003;29(2):127-33. vitamin C, also known as ascorbic acid, offers extra 3. Makola D, et al. J Nutr 2003;133:1339-46. advantages. Dietary intake of vitamin C along with iron Lysine increases utilization of nonheme iron, though 4. Zavaleta N, et al. Am J Clin Nutr 2000;71(4):956-61. rich sources enhances iron absorption significantly.5,9-11 the mechanism by which it does so is poorly understood. 5. Mehnaz S, et al. Indian J Comm Med 2006;31(3):201-3. Table 1. Increase in the mean hemoglobin at 30 and 100 days 6. Zimmermann MB, et al. Lancet 2007;370(9586):511-20. 7. Jackson K. US Pharm 2005;12:60-70. Day 0 Day 30 Mean Hb increase Day 100 Mean Hb increase Mean Hb (%) Mean Hb (%) after 30 days Mean Hb (%) after 100 days 8. Lynch SR. ASDC J Dent Child 1981;48(1):61-3. 9. Sharma A. Indian Pediatrics 2000;37:261-7. Controls 8.33 8.40 0.23 8.43 0.10 10. Gillespie S. Regional Office for South Asia Nov. 1997:92-3. Cases Subgroup I 8.30 9.24 0.94 11.02 2.72 11. Davidsson L. Iron Research Abstracts, 113_1998;67:8737. 12. Martinez- Torres C, et al. Am J Clin Nutr 1981;34:322-7. Cases Subgroup II 8.70 10.30 1.6 13.06 4.36 13. Ashmead HD. Arch Latinoam Nutr 2001;51(1 Suppl 1):13-21. IROSOL suspension At every step of life
- 55. Newsletters 2 Newsletters are a publications of regularly Herbs frequency. They provide Clinical Updates, Tinospora cordifolia References News and Views from across the globe. efficacy of T cordifolia extract was evaluated in patients with allergic 1. Badar VA, et al. J Ethnopharmacol. 2005; English name: Tinospora gulancha/ rhinitis. Results of the study showed 96(3):445-449. Indian tinospora that T cordifolia treatment brought 2. Rege NN, et al. Phytother Res. 1999;13(4): Sanskrit name: Guduchi about significant reduction in the 275-291. symptoms (such as sneezing and nasal 3. Leyon PV, Kuttan G. J Ethnopharmacol. Habit and Habitat discharge, obstruction, and pruritus) of allergic rhinitis.1 2004;90(2-3):233-237. 4. Singh N, et al. Immunopharmacol Tinospora cordifolia, an extensively Immunotoxicol. 2004;26(1):145-162. T cordifolia is known to possess spreading glabrous, perennial deciduous 5. Stanely P, et al. J Ethnopharmacol. 2000; adaptogenic,2 antineoplastic,3 twiner with succulent stems, is 70(1):9-15. immunomodulatory,4 antidiabetic,5 6. Mathew S, Kuttan G. J Exp Clin Cancer mainly found in the tropical regions antioxidant,6 hypolipidemic,7 anti- Res. 1997;16(4):407-411. of Indian subcontinent and China. inflammatory, analgesic, diuretic, 7. Stanely Mainzen Prince P, et al. T cordifolia often grows to a great height gastrointestinal protective,8 antimalarial,9 J Ethnopharmacol. 1999;64(1):53-57. and climbs up the trunks of large neem and hepatoprotective10 properties. 8. Panchabhai TS, et al. Phytother Res. trees. Its branches bear long thread- Medicinal Use Many studies have attributed these 2008;22(4):425-441. like aerial roots, smooth heart-shaped properties of T cordifolia to the 9. Singh RK. J Vector Borne Dis. 2005;42(1): In Ayurveda, T cordifolia, a potent leaves, unisexual greenish flowers presence of berberine or the bitter 36-38. rasayana and rejuvenating agent, (summer), and red berries (winter). substances. 10. Tasaduq SA, et al. Hum Exp Toxicol. is used for the treatment of several 2003; 22(12):639-645. ailments such as general weakness, Principal Constituents fever, dyspepsia, dysentery, gonorrhea, Product Range The principal components of T cordifolia secondary syphilis, urinary diseases, Abana, Bonnisan, Diabecon, Diakof, include tinosporin, tinosporide, cordifol, impotency, gout, viral hepatitis, skin Diarex, Evecare, Geriforte, Koflet, heptacosanol, clerodane furano diterpene, diseases, and anemia. Mentat, Mentat syrup, Purim, Rumalaya, diterpenoid furanolactone tinosporidine, In a randomized, double-blind, Rumalaya forte, Septilin, Septilin columbin, and b-sitosterol. placebo-controlled study, the syrup, Guduchi, and Chyavanaprasha. Boerhaavia diffusa observed that the antiproliferative and antiestrogenic properties of antihepatotoxic, antiasthmatic, antiurethritis activities.1 and English name: Spreading hogweed/ B diffusa are effective in the treatment Boerhavia of estrogen-dependent breast cancers.3 Product Range Sanskrit name: Punarnava Abana, Bonnisan, Diabecon, Evecare, A study conducted in Balb/c mice showed that punarnavine, the active Geriforte, V-Gel, Lukol, Punarnava, Habit and Habitat alkaloid present in B diffusa, has and Chyavanprasha. The genus Boerhaavia is found in the immunomodulatory activities that tropical, subtropical, and temperate increase the total white blood cell References regions of Australia, China, Egypt, count, bone marrow cellularity, 1. Awasthi LP, Verma HN. Available at: http:// www.agri-history.org/pdf/Boerhaavia.pdf India, Middle East countries, Pakistan, number of α-esterase positive cells, and 2. Kaur M, Goel RK. Evid Based Complement Sudan, Sri Lanka, South Africa, and circulating antibody titer and number Alternat Med. 2009. the United States. Boerhaavia diffusa, a of plaque-forming cells (PFC) in the 3. Sreeja S, Sreeja S. J Ethnopharmacol. perennial creeping weed native to India, spleen. The study also showed that 2009;126(2):221-225. is mainly found in the warm regions Medicinal Use punarnavine increased the proliferation 4. Manu KA, Kuttan G. Immunopharmacol Immunotoxicol. 2009;31(3):377-387. up to an altitude of 2000 meters in the of splenocytes, thymocytes, and In Ayurveda, B diffusa has been used 5. Manu KA, Kuttan G. J Exp Ther Oncol. Himalayan range. It can grow 1 meter bone marrow cells and reduced the as a diuretic, diaphoretic, laxative, 2008;7(1):17-29. or more in length. Its roots are stout and expectorant, and a potent antidote lipopolysaccharide-induced elevated 6. Manu KA, et al. Integr Cancer Ther. fusiform with a woody root stock.1 levels of proinflammatory cytokines Specifications to snake and rat bites. It is also used 2007;6(4):381-388. for the treatment of hepatitis, jaundice, such as TNF-α, IL-1b, and IL-6.4 7. Borrelli F, et al. Planta Med. Principal Constituents nephrotic syndrome, urinary disorders, B diffusa stimulates the cell- 2005;71(10):928-932. and stomach ache.1 mediated immune response5 and The major chemical compounds isolated from B diffusa include alkaloids In a study, the methanolic extract of has radioprotective effect against (punarnavine), amino acids, flavonoids, B diffusa roots has been found to possess γ-radiation-induced damage.6 The glycoproteins, lignans (liriodendron), anticonvulsant activity, probably due active compounds of B diffusa rotenoids (boeravinones A-F), to its calcium channel antagonistic exhibit spasmolytic,7 anti-inflammatory, punarnavoside, and ursolic acid.1 action.2 In another study, it is antifibrinolytic, antibacterial, antistress, Size: A 3 (8 x 11 inches) Immunosuppressive Properties of Flavonoids Isolated from Boerhaavia diffusa Linn S Pages: 8 everal plant extracts have been proliferation; mixed lymphocyte culture; of PBMCs, two-way mixed lymphocyte and mRNA transcript levels and evaluated for their immunomodu- lipopolysaccharide (LPS)-stimulated reactions (MLRs), NK cell cytotoxicity, LPS-stimulated TNF-α production latory properties. The ethanolic extract nitric oxide production by RAW 264.7; and LPS-induced NO production by in human PBMCs. It also blocked of Boerhaavia diffusa root has significant and PHA- and LPS-induced interleukin RAW 264.7; however, the hexane the DNA-binding activation of immunomodulatory effects. Hexane, (IL)-2 and tumor necrosis factor-alpha extract showed no activity. Purified nuclear factor-κB and AP-1, two Paper: 130 GSM Indian Art Paper chloroform, and ethanol extracts of (TNF-α) production. Their effects were Bd-I from the ethanolic extract inhibited major transcription factors centrally B diffusa, and two pure compounds also evaluated in neutrophil superoxide PHA-stimulated proliferation of PBMCs, involved in the expression of IL-2 (eupalitin-3-O-b-D-galactopyranoside production, natural killer (NK) cell two-way MLR, NK cell cytotoxicity, and and IL-2R gene, which are necessary [Bd-I] and eupalitin [Bd-II]), were cytotoxicity, and nuclear translocation LPS-induced NO production by RAW for T cell activation and proliferation. evaluated in vitro for their effect on of nuclear factor-kB and AP-1 in 264.7 equally or more effectively than Results of the study showed the selective Printing: 4 Color T cell mitogen (phytohemagglutinin; PHA-stimulated human PBMCs. the parent ethanolic extract at equivalent immunosuppressive activity of B diffusa PHA)-stimulated human peripheral blood mononuclear cell (PBMC) Chloroform and ethanol extracts inhibited PHA-stimulated proliferation dosage. Bd-I inhibited the production of PHA-stimulated IL-2 at the protein leaf extracts present in Bd-I, isolated and purified from the ethanolic extract. Source: Pandey R, et al. Int Immunopharmacol. 2005;5(3):541-553. Binding: Centre Stitch
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- 57. Conference Compendiums A Conference Compendium covers International and National conferences. Morbidity and Mortality Factors in Chronic Kidney Disease: Diabetic and Non-diabetic Patients (MereNa Study). Baseline Data A concise, yet comprehensive compilation Jose L Gorriz, Alberto M Castelao, Fernando De Alvaro, Aleix Cases, Jose Portoles, Jose Luno and Juan Navarro. On Behalf of the MERENA and GEENDIAB Study Group, Spain. The aim of this study was to analyse clinical characteristics, morbidity, laboratory data as well as clinical of a body of knowledge, compendium practices and adherence to guidelines of a cohort patients we observed that diabetic patients were includes Scientific Abstracts, Poster of patients with NFK-DOQI Stage 3/4 chronic kidney older (p 0,001) and presented with more disease (CKD) comparing diabetics versus non- diabetics (MereNa Study). comorbid conditions (cardiovascular disease 48% vs 31% vs, ischaemic heart disease 20% vs Presentations at a conference. MereNa is a prospective, multicentric, 14%, peripheral vascular disease 30% vs 11% and observational study of two cohorts of patients heart failure 48% vs 31%, all p 0.05). Diabetics (diabetic vs non-diabetic) who will be followed for presented with higher BMI, GFr, proteinuria and more than 3 years in the outpatient’s clinic analysing serum potassium (all p 0.001). basal clinical characteristics, morbidity and mortality Diabetics showed higher systolic blood pressure factors. The inclusion criteria were: CKD stage 3 and (145 ± 19 vs 139 ± 19 mmHg) (p 0.001) pulse 4 of NKF-DOQI, life expectancy 1 year and giving pressure (p 0.001) heart rate (p = 0.039) and their informed consent. From December 2003 to Cornell product in eKG (p = 0.045). March 2004 we have included 1,115 consecutive Guidelines target blood pressure objective patients visited in the outpatient clinic of 74 Spanish (≤130/80 or ≤125/75 if proteinuria 1g/day) was Nephrology centres. We present baseline data. achieved only in 25% of the patients (21% in Sixty-four percent were males and 36% females, diabetics vs 27% in non-diabetics). C-LDL was ≥100 mean age was 67 ± 13 (r: 19-96) years. Stage 3: mg/dl in 35% of patients (28% in non-diabetics and 47% and 53% stage 4. There were 40% diabetic 47% in diabetics, p 0.001). and 93% hypertensive. The aetiology of CKD Conclusion: Patients with CKD followed by was: Glomerular 12%, interstitial 11%, vascular the Nephrology clinic have high morbidity 30%, diabetic nephropathy 23%, PKrD 4% and (particularly cardiovascular morbidity); this is not well-established 20%. Forty four percent of more common in diabetics. anemia is a highly the patients were submitted for GP physicians. prevalent problem, and almost half of the patients The basal data shown: Serum creatinine 2.4 ± have iron deficiency. High blood pressure affects 0.7 mg/dl, GFr (Cockroft-G) 31 ± 10 ml/min, Hb: almost all patients. However, the optimal control 12.7 ± 1.6 g/dl, systolic blood pressure 142 ± rate is low, and achieving optimal control is more 19 mmHg, diastolic blood pressure 76 ± 11 mmHg, difficult in diabetics. These results will help us to pulse pressure 65 ± 18 mmHg. anaemia (eBPG for understand the characteristics of patients with Stage anaemia criteria) was present in 45.5% of patients and iron deficiency (ferritin 100 ng/ml) in 47% of patients. erythropoietic agents were given in 3/4 CKD, and also the associated morbidity and clinical care provided (adherence to the Guidelines). Specifications 16% of patients with CKD stage 3 and 32% in CKD stage 4. BNP and NT-proBNP as Diagnostic Size: A4 Size When we compare diabetic versus non-diabetic and Prognostic Markers in Haemodialysis Patients Paper: 48+4 Pages Stephanie Graf, Sharzad Ashayer, Mohammed Atrissi, Winfried Fassbinder, Harald Renz and Hans Guenther Wahl. Department of Nephrology, Hospital of Fulda, Fulda, Germany; Department of Clinical Chemistry and Molecular Diagnostics, Philipps-University of Marburg, Marburg, Germany. B-type natriuretic peptide (BNP) and NT-proBNP the biologically inactive N-terminal fragment of , proBNP are used as cardiac biomarkers in the diagnosis and treatment of chronic heart failure. Both forms , can be elevated in patients with chronic kidney disease, who often suffer from cardiovascular diagnostic and prognostic value of both parameters was analysed. Printing: 4+2 Color Offset Printing related diseases and heart failure. In this study, the BNP (aDVIa BNP assay, Bayer) and NT- Paper: 210/90 GSM Indian Art Paper Binding: Center Stitch
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- 59. Product Monographs Product monograph is a factual, scientific document that describes a drug as a el.com) is a Founded in 1985, Corel Corporation (www.corel.com) is a whole: its properties, indications of use, e for home and enterprise leading technology company that offers software for home and small business users, creative professionals and enterprise efficacy, backed by scientific data. nada, Corel’s customers. With its headquarters in Ottawa, Canada, Corel’s ket under the common stock trades on the Nasdaq Stock Market under the ge under the symbol CORL and on the Toronto Stock Exchange under the symbol COR. (c) 2002 Corel Corporation. All rights reserved. el.com) is a Founded in 1985, Corel Corporation (www.corel.com) is a e for home leading technology company that offers software for home and enterprise and small business users, creative professionals and enterprise nada, Corel’s customers. With its headquarters in Ottawa, Canada, Corel’s ket under the common stock trades on the Nasdaq Stock Market under the ge under the symbol CORL and on the Toronto Stock Exchange under the symbol COR. Founded in (c) 2002 Corel Corporation. All rights reserved.Founded in leading 1985, Corel Corporation (www.corel.com) is a leading me and small technology company that offers software for home and small prise nada, Corel’s business users, creative professionals and enterprise customers. With its headquarters in Ottawa, Canada, Corel’s Specifications ket under the common stock trades on the Nasdaq Stock Market under the ge under the symbol CORL and on the Toronto Stock Exchange under the symbol COR. Size: A5 size (c) 2002 Corel Corporation. All rights reserved. Paper: 16+4 Printing: 4+2 Color Printing Paper: 210/90 GSM Indian Art Paper Binding: Center Stitch 1
- 60. Head Office: 39Daryacha, Hauz Khas Village, New Delhi, India. e-Mail: emedinews@gmail.com, Website: www.ijcpgroup.com emedinews is now available online on www.emedinews.in or www.emedinews.org From the Desk of Editor in Chief Padma Shri and Dr BC Roy National Awardee Dr KK Aggarwal Head Office: 39 Daryacha, Hauz Khas Village, New Delhi, India. e-Mail: emedinews@gmail.com, Website: www.ijcpgroup.com President, Heart Care Foundation of India; Sr Consultant emedinews is now available online on www.emedinews.in or www.emedinews.org and Dean Medical Education, Moolchand the Desk of EditorMember, Delhi Medical Council; Past President, Delhi Medical Association; From Medcity; in Chief Past President,and Dr BC Roy National Awardee Padma Shri IMA New Delhi Branch; Past Hony Director. IMA AKN Sinha Institute, Chairman Dr KK Aggarwal IMA Academy Heart Medical Specialities Hony Finance Secretary National IMA; Editor in Chief President, of Care Foundation of India; Sr Consultant and Dean Medical Education, Moolchand Medcity; Member, Delhi Medical Council; Past President, Delhi Medical Association; IJCP Group of Publications Hony Visiting Sinha Institute, Chairman Past President, IMA New Delhi Branch; Past Hony Director. IMA AKN Professor (Clinical Research) DIPSAR IMA Academy of Medical Specialities Hony Finance Secretary National IMA; Editor in Chief IJCP Group of Publications Hony Visiting Professor (Clinical Research) DIPSAR 8thJanuary 2011, Saturday Saturday 8th January 2011, Scientists have identifiedfor 90% of Risks for 90% Top 10 Stroke Risks the top 10 for risks Risks of of randomized controlled of Clinical randomized controlled dietary trial reported in the American Journal Top 10 Stroke Risks ResponsibleResponsiblestroke90% ofresponsibleStrokeStroke Nutrition. dietary trial reported in the American Journal the forthcoming edition of risks responsible HCC Treated of Clinical Nutrition. of risks of stroke. In INTERSTROKE study, published online first Scientists have identified and in atop 10 strokethe Lancet, Canadian authors fromfor 90% with Resection has Lower Recurrence Rate vs Radiofrequency Ablation of risks of stroke. In INTERSTROKE instudy, published online first Hung HCC Treated the JanuaryResection has Lower Recurrence Rate vs McMaster University used data from 6,000 people (3,000 cases of Hung-Hsu and colleagues report in issue of Clinical Gastroenterology and Hepatology even with stroke and 3,000 controls) 22 countries around the world. They though percutaneous and in a forthcoming edition patients who’dLancet, Canadian authorsradiofrequency ablation and surgical resection for small hepatocellular looked at of the had a first acute stroke and compared them from with people who’d not had a stroke. Radiofrequency Ablation carcinomas have comparable survival rates, patients who underwent McMaster University used data from High blood pressure, smoking, waist-to-cases of procedure have a higher rate of cancer recurrence than 6,000 people (3,000 the ablation The authors found the following 10 risk factors to be significantly stroke and 3,000 controls) ratiomellitus (typeobesity), diet,intake, stress andthe world.observations stressHung-Hsu close surveillance after local associated with stroke: those who had surgical resection. TheHung stated that these authors and colleagues report in the January issue of hip in (abdominal 22 countries around depression and They physical activity, blood lipids, upon the need for looked at patients who’d heart for all stroke. together, thesestroke and comparedablation therapy.” Clinical Gastroenterology and Hepatology even though percutaneous diabetes 2), alcohol had a first acute risk factors accounted for 90% of Insecticidal Nets don’t Reduce Leishmania Risks disorders. Put them with people who’d not had arisk factors were all significant for ischaemic stroke - caused by Results of a paired cluster-randomized trial note that using durable surgical resection for small hepatocellular radiofrequency ablation and risks These stroke. a blood clot blocking a blood vessel in the brain. High blood pressure, carcinomas have comparable survival rates, patients who underwent insecticidal nets do not significantly improve on existing measures to The authors found the followingintracerebral diet and alcohol intakebleeding significantly villages in threeinfection onandprocedure with a a higher rate of cancer recurrence than 10 risk factors to were significant control Leishmaniathe ablation theone Indian district have smoking, waist-to-hip ratio, risk factors for haemorrhagic stroke - be into the trial included donovani Nepalese Indian subcontinent. The associated with stroke: brainan important ratio for bad to good blood lipids for haemorrhagic high reporteddurablethose who hadIntervention clusters resection. The authors stated that these High The risk of ischemic stroke but smoking, waist-to- incidence of visceral leishmaniasis. treatment; control was tissue. blood pressure, not (apolipoproteins) were given insecticidal nets, deltamethrin surgical hip ratio (abdominal obesity), diet, physical activity, blood clusters continued observationsuntreated nets.upon the need for close surveillance after local stroke. Targeted population-based interventions that reduce blood lipids, with existing conventional strategies of irregular insecticide residual spraying and use of stress The results pressure and smoking, and promote physical (WebMD) diabetes mellitus (type 2), KK Aggarwal intake, stress and depressionIndianno significant reductionreceivingrate of L. donovani infection Dr alcohol showedand Nepalese villages in the long-lasting insecticidal nets in and ablation therapy.” heart disorders. Put together,inthese risk factors accounted for 90% of measures. There is also no effect on the rate of Editor Chief ———————————————————————————— vs usual control clinical leishmaniasis. The study is published online 29 December risks for all stroke. International News 2010 in BMJ. Insecticidal Nets don’t Reduce Leishmania Risks These risk factors were all significant foronischaemicCare in basic caused is IUI? What is the Averageof a Rate of IUI? How many The 2010 AHA Guidelines Cardiac Arrest Change from “A-B-C” to “C-A-B.” A major change stroke - life Infertility UpdateResults Success paired cluster-randomized trial note that using durable What by a blood clot blocking a blood vesselaway from(taught with the approach of“A-B-C”) Cyclesaof IUI can insecticidalprocedure, washednot significantly improve on existing measures to support is a step in the the traditional mnemonic airway- IUI is simple OPD procedure. In this nets do capacitated breathing-chest compressions brain. High blood pressure, be Tried? smoking, waist-to-hip ratio, diet for this change. compressions (“C-A-B”). Theresignificantput in the uterus. The ovary is stimulated by giving hormone infection on the Indian subcontinent. The and alcohol intake were are sperms are to first establishing good chest several reasons control Leishmania donovani injections to produce multiple follicles and the procedure is carried out risk factors for intracerebral haemorrhagic stroke - tachycardia (VT), into the are trialto included have had a goodin three Nepalese and one Indian district with a • Most survivors of adult cardiac arrest have an bleeding ventricular fibrillation (VF) or pulseless ventricular initial rhythm of when the eggs about be released. We villages success rate with this method and recommend it as the first line of treatment brain tissue. The ratio ofand these patients are best blood lipidschest compressions in patients who have patent tubes and a reasonably good semen count. visceral leishmaniasis. Intervention clusters bad to good treated initially with (apolipoproteins) high reported incidence of and early defibrillation rather than airway management. Success rate varies according to the indication but around 15-18% can was an important risk for Airway management, whether mouth-to-mouth breathing, bagging, be considered good. Most couples conceivedurable insecticidal nets, deltamethrin treatment; control • ischemic stroke but not for haemorrhagic were given within first three cycles of stroke. Targeted population-based Airway management aisdelaylonger recommended toblood then probably turncontinued with existing conventional strategies of irregular six IUI cycles clusters to IVF-ET. IUI, in subsequent cycles the positive outcome is less. One can try up chest compressions. interventions that reduce or endotracheal intubation, often results in of initiation of good no pressure and smoking, and seconds. The 30 compressions are (WebMD) to precede 18 promote physical now recommended until after the first cycle of chest compressions –– 30 compressions in insecticide residualKaberi Banerjee and use of untreated nets. The results −Dr. spraying the 2 ventilations, which previous guidelines had recommended at the Women’s Health: Preventing Top 10significant reduction in the rate of L. donovani infection showed no Threats (Mayo Clinic) Dr KK Aggarwal start of resuscitation. Injuries • Only a minority of cardiac arrest victims receive bystander CPR. The leading cause infatal accidents and women is motor vehicle of Indian among Nepalese villages receiving long-lasting insecticidal nets Editor in Chief It is believed that a significant obstacle to bystanders performing CPR vs usual control measures. There is also no effect on the rate of crashes. To reduce your risk of a deadly crash: is their fear of doing mouth-to-mouth breathing. By changing the ————————————————————————————your seatclinical leishmaniasis. The study is published online 29 December initial focus of resuscitation to chest compressions rather than airway maneuvers, it is thought that more patients will receive important • Wear belt. • Follow the speed limit. • Don’t drive under the influence of alcohol or any other International News bystander intervention, even if it is limited to chest compressions. −Dr GM Singh substances. 2010 in BMJ. • Don’t drive while sleepy The 2010 AHA Guidelines onmay notgivenBest Arrestfor Trauma Victims site Falls and poisoning also pose major women’s vision checked, using Intravenous Cardiac a trauma victim at an accident IV Fluids fluids be to Treatment Care Infertility Update threats. Take common-sense precautions, such as having your health may not be the best treatment and in many cases may actually be Change from “A-B-C” to “C-A-B.” A the risk that a patient will die, according nonslip mats in thehome. placing carbon monoxide detectors near the Average Success Rate of IUI? How many counterproductive, increasing major change in basic life your What is IUI? What is the bedrooms in tub and support is a step away tofrompublished online in the Annals ofMonica and Brahm Vasudev airway- Cycles of IUI can be Tried? a study the traditional approach of Lab Update −Dr Surgery journal. breathing-chest compressions (taughtof withPortions of Whole-grain Foods Allergies are hypersensitivities, a simplepeople. procedure. In this procedure, washed capacitated Daily Consumption Three the mnemonic “A-B-C”)that do IUI isreactions in mostof the immune system to substances not cause overreactions OPD TESTS to first establishing good chest Lowerof 3 portions of whole-grain foods is linkedThereblood specific IgE testing: Immunoassay and allergen-specific IgE The ovary is stimulated by giving hormone may Carry compressions (“C-A-B”). Daily consumption Cardiovascular Risk to are are thatspermsscreen for type in the uterus. Allergen tests are used to are put I LINE BLOT several reasons for this change.lowering blood pressure, according middle-aged people antibodies. lower cardiovascular disease risk in healthy, mainly by to the results of a injections Arpanproduce Navin Dang follicles and the procedure is carried out −Dr to Gandhi and Dr multiple • Most survivors of adult cardiac arrest have an initial rhythm of when the eggs are about to be released. We have had a good success ventricular fibrillation (VF) or pulseless ventricular tachycardia (VT), rate with this method and recommend it as the first line of treatment and these patients are best treated initially with chest compressions in patients who have patent tubes and a reasonably good semen count. and early defibrillation rather than airway management. Success rate varies according to the indication but around 15-18% can • Airway management, whether mouth-to-mouth breathing, bagging, be considered good. Most couples conceive within first three cycles of or endotracheal intubation, often results in a delay of initiation of good IUI, in subsequent cycles the positive outcome is less. One can try up chest compressions. Airway management is no longer recommended to six IUI cycles then probably turn to IVF-ET. until after the first cycle of chest compressions –– 30 compressions in −Dr. Kaberi Banerjee 18 seconds. The 30 compressions are now recommended to precede the 2 ventilations, which previous guidelines had recommended at the Women’s Health: Preventing Top 10 Threats (Mayo Clinic) start of resuscitation.
- 61. eMedinewS is thefirst national daily electronic medical newspaper of India. It was launched on July 1, 2009 toHead Office: 39 Daryacha, Hauz Khas Village, New Delhi, India. e-Mail: emedinews@gmail.com, Website: www.ijcpgroup.com mark Doctors’ day and is designed for Practitioners, Medical Students and other health professionals. IJCP’s eMedinewS offers dailyemedinewsrelated to important medical developments, new www.emedinews.org updates is now available online on www.emedinews.in or launches, controversies, breakthroughs, new drugs, editorials, national/international in Chief columns and unique interactive sessions like From the Desk of Editor news, Dr Good Dr Bad, Make Sure etc. It is emailed Shri and Dr BCto 50,000 Awardee and health journalists apart from Padma every day Roy National doctors being posted on www..emedinews.in. Dr KK Aggarwal President, Heart Care Foundation of India; Sr Consultant and Dean Medical Education, eMedinewS Interactive Workshops President, IMA New DelhiDelhi Medical Council; Past President, Delhi Medical Association; Moolchand Medcity; Member, Past Branch; Past Hony Director. IMA AKN Sinha Institute, Chairman These interactive workshops of around 100 doctors areof held twice a month for medical doctors at various Chief IMA Academy Medical Specialities Hony Finance Secretary National IMA; Editor in locations IJCP Group of Publications Hony Visiting Professor (Clinical Research) DIPSAR in Delhi. These 2-hour workshops cover updated subjects in the form of live interactions. Sponsorship opportunities 8th January 2011, Saturday available on request. Top 10 Stroke Risks Responsible for 90% of Risks of Stroke randomized controlled dietary trial reported in the American Journal Scientists have identified the top 10 stroke risks responsible for 90% of Clinical Nutrition. Participation OpportunitiesIn edition of the Lancet, Canadian authors from of risks of stroke. and in a forthcoming INTERSTROKE study, published online first HCC Treated with Resection has Lower Recurrence Rate vs Radiofrequency Ablation McMaster University used data from 6,000 people (3,000 cases of Hung-Hsu Hung and colleagues report in the January issue of Advertise on the net edition or on the daily email newspaper stroke and 3,000 controls) in 22 countries around the world. They looked at patients who’d had a first acute stroke and compared them Clinical Gastroenterology and Hepatology even though percutaneous with people who’d not had a stroke. radiofrequency ablation and surgical resection for small hepatocellular eMedinewS Radiocast carcinomas have comparable survival rates, patients who underwent The authors found the following 10 risk factors to be significantly the ablation procedure have a higher rate of cancer recurrence than associated with stroke: High blood pressure, smoking, waist-to- those who had surgical resection. The authors stated that these hip ratio (abdominal obesity), diet, physical activity, blood lipids, observations stress upon the need for close surveillance after local diabetes mellitus (type 2), alcohol intake, stress and depression and Radiocast news is being webcast everyday in eMedinewS. The news can be preceded or followed by a 10-second slot heart disorders. Put together, these risk factors accounted for 90% of ablation therapy.” risks for all stroke. Insecticidal Nets don’t Reduce Leishmania Risks for advertisement. These risk factors were all significant for ischaemic stroke - caused by Results of a paired cluster-randomized trial note that using durable a blood clot blocking a blood vessel in the brain. High blood pressure, insecticidal nets do not significantly improve on existing measures to Who can participate smoking, waist-to-hip ratio, diet and alcohol intake were significant risk factors for intracerebral haemorrhagic stroke - bleeding into the control Leishmania donovani infection on the Indian subcontinent. The trial included villages in three Nepalese and one Indian district with a brain tissue. The ratio of bad to good blood lipids (apolipoproteins) high reported incidence of visceral leishmaniasis. Intervention clusters was an important risk for ischemic stroke but not for haemorrhagic were given durable insecticidal nets, deltamethrin treatment; control Organizations directly/indirectly promoting health products/pharmaceutical cos/Hospitals/Diagnostic centres/Laboratories stroke. Targeted population-based interventions that reduce blood clusters continued with existing conventional strategies of irregular insecticide residual spraying and use of untreated nets. The results pressure and smoking, and promote physical (WebMD) owners/ banks/insurance cos/investment com’s/ individual doctors etc. Dr KK Aggarwal showed no significant reduction in the rate of L. donovani infection in Indian and Nepalese villages receiving long-lasting insecticidal nets Editor in Chief vs usual control measures. There is also no effect on the rate of Participation Opportunities ———————————————————————————— International News clinical leishmaniasis. The study is published online 29 December 2010 in BMJ. The 2010 AHA Guidelines on Cardiac Arrest Care Infertility Update eMedinewS Live Webcast a step awaytofrom the traditional approachinofbasic life Change from “A-B-C” support is “C-A-B.” A major change airway- What is IUI? What is the Average Success Rate of IUI? How many Cycles of IUI can be Tried? breathing-chest compressions (taught with the mnemonic “A-B-C”) IUI is a simple OPD procedure. In this procedure, washed capacitated A 2- 12 hours webcast on firstsubject this change.whole conference There are done in a studio, onsite, in a hospital setting or to a establishingor the compressions (“C-A-B”). can be several reasons for good chest sperms are put in the uterus. The ovary is stimulated by giving hormone injections to produce multiple follicles and the procedure is carried out in the conference venue. •You can see (VF) or pulseless ventricular tachycardia (VT), Most survivors of a few examples an initial rhythm of ventricular fibrillation adult cardiac arrest have at www.emedinews.in (Details on request) when the eggs are about to be released. We have had a good success rate with this method and recommend it as the first line of treatment and these patients are best treated initially with chest compressions in patients who have patent tubes and a reasonably good semen count. and early defibrillation rather than airway management. Success rate varies according to the indication but around 15-18% can • Airway management, whether mouth-to-mouth breathing, bagging, be considered good. Most couples conceive within first three cycles of or endotracheal intubation, often results in a delay of initiation of good IUI, in subsequent cycles the positive outcome is less. One can try up chest compressions. Airway management is no longer recommended to six IUI cycles then probably turn to IVF-ET. until after the first cycle of chest compressions –– 30 compressions in −Dr. Kaberi Banerjee 18 seconds. The 30 compressions are now recommended to precede the 2 ventilations, which previous guidelines had recommended at the Women’s Health: Preventing Top 10 Threats (Mayo Clinic) start of resuscitation.
- 62. eMedinewS Audio CDs Head Office: 39 Daryacha, Hauz Khas Village, New Delhi, India. e-Mail: emedinews@gmail.com, Website: www.ijcpgroup.com Audio CDs with “eMedinewS credit hours” on a subject with periodic fun breaks with or www.emedinews.org emedinews is now available online on www.emedinews.in songs, music, jokes and advertisers message. It can also be in the form the Desk of Editor in Chiefmusic or jokes intermixed with health subject From of songs, poetry, messages. (Details on request) Padma Shri and Dr BC Roy National Awardee Dr KK Aggarwal eMedinewS Audio PPT Medical Slides Heart Care FoundationMedical Council; Past President, Dean Medical Association; President, Moolchand Medcity; Member, Delhi of India; Sr Consultant and Delhi Medical Education, Past President, IMA New Delhi Branch; Past Hony Director. IMA AKN Sinha Institute, Chairman This is a new initiative started by eMedinewS. Here “audio PPT” slides have links inSecretary Nationalnewspaper Chief IMA Academy of Medical Specialities Hony Finance eMedinewS IMA; Editor in being IJCP Group of Publications Hony Visiting Professor (Clinical Research) DIPSAR sent to 50000 doctors everyday and also on the web at www.emedinews.in. This will be a series of 100 lectures in the form of audio PPTs. Top10medical experts willfor 90% of Risks to Stroke 2011,the subject. dietary trial reported in the American Journal Top Stroke Risks Responsible be invitedJanuary on Saturday Each PPT can be sponsored 8th of speak randomized controlled through an educational grant (Details on the top 10 stroke risks responsible for 90% of Clinical Nutrition. Scientists have identified request) of risks of stroke. In INTERSTROKE study, published online first HCC Treated with Resection has Lower Recurrence Rate vs eMedinewS PPT and in a forthcoming edition of the Lancet, Canadian authors from Radiofrequency Ablation McMaster University used data from 6,000 people (3,000 cases of stroke and 3,000 controls) in 22 countries around the world. They Hung-Hsu Hung and colleagues report in the January issue of looked at patients who’d had a first acute stroke and compared them Clinical Gastroenterology and Hepatology even though percutaneous radiofrequency ablation and surgical resection for small hepatocellular These are clinically oriented PPTs with “eMedinewS credit hours” on a given subject that can be used by various with people who’d not had a stroke. The authors found the following 10 risk factors to be significantly carcinomas have comparable survival rates, patients who underwent the ablation procedure have a higher rate of cancer recurrence than speakers to deliver talks or for self learning. associated with stroke: High blood pressure, smoking, waist-to- hip ratio (abdominal obesity), diet, physical activity, blood lipids, those who had surgical resection. The authors stated that these observations stress upon the need for close surveillance after local diabetes mellitus (type 2), alcohol intake, stress and depression and ablation therapy.” eMedinewS Virals heart disorders. Put together, these risk factors accounted for 90% of risks for all stroke. Insecticidal Nets don’t Reduce Leishmania Risks These risk factors were all significant for ischaemic stroke - caused by Results of a paired cluster-randomized trial note that using durable a blood clot blocking a blood vessel in the brain. High blood pressure, insecticidal nets do not significantly improve on existing measures to These are “designers PPTs” with or without “audio voice over” to be for free circulation. smoking, waist-to-hip ratio, diet and alcohol intake were significant control Leishmania donovani infection on the Indian subcontinent. The risk factors for intracerebral haemorrhagic stroke - bleeding into the trial included villages in three Nepalese and one Indian district with a eMedinewS Video Gallery brain tissue. The ratio of bad to good blood lipids (apolipoproteins) high reported incidence of visceral leishmaniasis. Intervention clusters was an important risk for ischemic stroke but not for haemorrhagic were given durable insecticidal nets, deltamethrin treatment; control stroke. Targeted population-based interventions that reduce blood clusters continued with existing conventional strategies of irregular pressure and smoking, and promote physical (WebMD) insecticide residual spraying and use of untreated nets. The results Interactive video lectures are posted on eMedinewS Video Gallery at www.emedinews.in and the links appear in the Dr KK Aggarwal showed no significant reduction in the rate of L. donovani infection in Indian and Nepalese villages receiving long-lasting insecticidal nets Editor in Chief eMedinewS newspaper being emailed to 50000 doctors everyday. The sponsorship avenues are available for each vs usual control measures. There is also no effect on the rate of ———————————————————————————— clinical leishmaniasis. The study is published online 29 December 2010 in BMJ. video. List can be checked on the News International website. The 2010 AHA Guidelines on Cardiac Arrest Care Infertility Update Change from “A-B-C” to “C-A-B.” A major change in basic life eMedinewS SMS What is IUI? What is the Average Success Rate of IUI? How many support is a step away from the traditional approach of airway- Cycles of IUI can be Tried? breathing-chest compressions (taught with the mnemonic “A-B-C”) IUI is a simple OPD procedure. In this procedure, washed capacitated to first establishing good chest compressions (“C-A-B”). There are sperms are put in the uterus. The ovary is stimulated by giving hormone Daily SMS to a specified segment with the company name prefix or suffix with a one-liner health message. It can several reasons for this change. • Most survivors of adult cardiac arrest have an initial rhythm of injections to produce multiple follicles and the procedure is carried out when the eggs are about to be released. We have had a good success be text-based or audio-based. ventricular fibrillation (VF) or pulseless ventricular tachycardia (VT), and these patients are best treated initially with chest compressions rate with this method and recommend it as the first line of treatment in patients who have patent tubes and a reasonably good semen count. and early defibrillation rather than airway management. Success rate varies according to the indication but around 15-18% can • Airway management, whether mouth-to-mouth breathing, bagging, be considered good. Most couples conceive within first three cycles of or endotracheal intubation, often results in a delay of initiation of good IUI, in subsequent cycles the positive outcome is less. One can try up chest compressions. Airway management is no longer recommended to six IUI cycles then probably turn to IVF-ET. until after the first cycle of chest compressions –– 30 compressions in −Dr. Kaberi Banerjee 18 seconds. The 30 compressions are now recommended to precede the 2 ventilations, which previous guidelines had recommended at the Women’s Health: Preventing Top 10 Threats (Mayo Clinic) start of resuscitation.
- 63. IJCP Pharma Solutions DrugLaunches and Promotions Comprehensive one month launch strategy includes 50,000 email daily, 50,000 SMS daily, eMedinewS daily column, adv in all IJCP journals, one web cast live, one 200-doctor session in Delhi and one press release. (Details on request) MR Training 4 hours in-house training modules including speaking skills, stress management, etiquettes and subject training. (Details on request) Round Table Conferences These are scientific sessions with 10-20 doctors, with a moderator, opinion building, live audio and video recording, transcription and compilation of audio/video CD and a print white paper. (Details on request) eMedinewS Awards and Laurels eMedinewS Doctor of the Year Award, eMedinewS Lifetime Achievement Award, eMedinewS Most Popular Doctor of the Year Award, eMedinewS Distinguished Speaker of the Year Award, eMedinewS Singer of the Year Award are given during the “eMedinewS revisiting conference” in January and eMedinewS Doctors’ Day Awards are given in July every year. One can sponsor a title of the award. (Details on request)
- 64. Our Milestones 1990 Indian Journalof Clinical Practice launched as a monthly medical journal 1992 Medinews, India’s first most comprehensive medical newspaper launched 1996 Asian Journal of Obs Gyne Practice launched as the 1st speciality journal under the ‘Asian’ Series 1996 Indian Journal of Medilaw, a unique venture in educating doctors about healthcare and law 1997 Asian Journal of Orthopedics and Rheumatology launched 1998 OUR Asian Journal of Clinical Cardiology launched 1999 Asian Journal of Diabetology launched 2004 MIlEStOnES IJCP spread its wings and collaborated with American Family Physician 2005 Asian Journal of Critical Care launched 2007 Series of 100 Clinical Questions in Gastroenterology launched under medical grant from Dr Reddy’s Laboratories 2008 Dr KK Aggarwal received the prestigious Dr BC Roy National Award from the President of India, Smt. Pratibha Dev Singh Patil for his unique contribution in the health sector 2009 Launch of eMedinewS, first National Daily eMedical Newspaper of India 2010 Dr KK Agarwal received Padma Shri award from the President of India, Smt. Pratibha Dev Singh Patil for his unique contribution in the health sector “We believe this is the beginning of our journey”