The document discusses the relationship between water solubility and extraction design, emphasizing that solubility must be greater in the aqueous base for effective differential extraction. It notes that this principle applies to the salts of acids, with some exceptions. The text repeats the importance of these solubility considerations in the extraction process.

1. If you are talking about an extraction design, the the water solubility has to be
greater in the aqueous base because of the greater solubility of the salts of the acids (with few
exceptions), again presuming a differential extraction aqueous to organic.
Solution
If you are talking about an extraction design, the the water solubility has to be
greater in the aqueous base because of the greater solubility of the salts of the acids (with few
exceptions), again presuming a differential extraction aqueous to organic.