Nowadays, all animal production is concerned with vaccination. This is an essential technique for the protection of livestock health which, however, entails significant costs for stock breeders. Maximizing the efficiency and profitability of prophylactic vaccination strategies is therefore a major stake. To achieve this, new avenues are constantly explored. One of these concerns is the use of new molecules extracted from seaweeds to help optimize the stimulation of the natural defences of the body and its response to vaccination strategies.
Polysaccharides are polymers of monosaccharides that can be formed from pentoses or hexoses. The most common hexosans in physiology include starch, cellulose, and dextrin. Starch is insoluble in water and turns blue with iodine. Cellulose is the structural substance of plants and does not dissolve in water. Glycogen is stored in the liver and muscles and supplies glucose to the body.
FISH FARMING TECHNOLOGY: The use of feed in recirculating aquaculture systems...International Aquafeed
One of the greatest operating costs in aquaculture is the use of commercial feed pellets, which can comprise of up to 50-60 percent of total expense in some farms.
FISH FARMING TECHNOLOGY: The Faivre equipped trout farms of AbbevilleInternational Aquafeed
Amidst the picturesque countryside of Abbeville, Northern France, Darren Parris, Tom Blacker and Peter Parker from the International Aquafeed team, spent an afternoon late last year visiting trout farms. Our hosts were Phillip Jorgensen, fish farms manager, and Aubert Faivre, who is sales manager for Faivre.
The Salmonidae family, collectively known as Salmonids, comprises of salmon, trout, chars, freshwater whitefishes, and graylings, but it is the trout and Atlantic salmon, of the genus Salmo, which gives the family their name. A slender teleost fish, they can range in size between just 13 cm to a whopping 2 m in length. With a single row of sharp teeth, Salmonids are predators, choosing to feed on smaller fish, aquatic insects and small crustaceans. Despite spawning in fresh water Salmonids are mostly anadromous, spending their lives at sea, choosing only to return to rivers to reproduce.
Innovation nation - How new developments in aquaculture are boosting the Scot...International Aquafeed
With an estimated market value of over £1.8 billion and Scottish salmon exports alone reaching over £500 million, Scotland’s aquaculture sector is fast becoming a core pillar for the future growth of the Scottish economy. However, with such a steep increase in the demand for fish products, there is a real need for innovation within the sector to stay ahead of the curve and provide a sustainable supply of healthy protein; not only for the present but for the future of a market that appears set to keep growing. Ahead of Aquaculture UK, CEO of the Scottish Aquaculture Innovation Centre (SAIC), Heather Jones, shares some of the organisation’s forays into finfish research projects and the ways in which is working with both industry and academia to enhance the whole of the Scottish aquaculture sector.
The Asian catfish Pangasius, Pangasianodon hypophthalmus is recognised as a leading aquaculture food fish on world markets. The commercial culture of Pangasius was developed in the mid 1990’s in Vietnam and quickly expanded to production levels of nearly one million tons per year. Other countries including Thailand, Cambodia, Myanmar, Indonesia, Philippines, Bangladesh and India have adapted Pangasius as part of their aquaculture production. Pangasius can be successfully cultured in most tropical regions of the world however countries in the Western Hemisphere have been slow to embrace Pangasius aquaculture, in part, due to the lack of practical knowledge of the species food requirements during the larval and fry stages.
Mud crabs, also known as mangrove crabs, occur widely in estuaries and along tropical, subtropical and warm temperate coasts in the world. There are four species of mud crab (Family: Portunidae), Scylla serrata, S. tranquebarica, S. paramamosain and S. olivacea that are the focus of both commercial fisheries and aquaculture production throughout their distribution. They are among the most valuable crab species in the world, with the bulk of their commercial production sent live to market.
The European lobster (Homarus gammarus) is an ecologically important species of the North-eastern Atlantic which supports wild trap fisheries that are worth around £30 million each year to the UK alone. By weight the species is the highest-value seafood among those landed regularly in the UK and Ireland, where 75 percent of the ~5,000t annual landings for the species are made. As such, lobsters provide essential diversity to fragile inshore fisheries and vital income for rural coastal economies. However, populations across its range are pressured by rising exploitation, from which traditional fisheries management has failed to prevent extensive regional stock collapses in the recent past, and now struggles to stimulate recovery. While lobsters have long been transported as a live export commodity, chiefly to France and the Iberian peninsula, emerging markets, particularly those in East Asia, threaten to create additional demand for the species which far exceeds current capture yields. Improvements in hatchery rearing success have seen a number of recent aquaculture initiatives employed, in the hope of both generating restoration and improved sustainability of wild harvests, and instigating commercial aquaculture possibilities.
Polysaccharides are polymers of monosaccharides that can be formed from pentoses or hexoses. The most common hexosans in physiology include starch, cellulose, and dextrin. Starch is insoluble in water and turns blue with iodine. Cellulose is the structural substance of plants and does not dissolve in water. Glycogen is stored in the liver and muscles and supplies glucose to the body.
FISH FARMING TECHNOLOGY: The use of feed in recirculating aquaculture systems...International Aquafeed
One of the greatest operating costs in aquaculture is the use of commercial feed pellets, which can comprise of up to 50-60 percent of total expense in some farms.
FISH FARMING TECHNOLOGY: The Faivre equipped trout farms of AbbevilleInternational Aquafeed
Amidst the picturesque countryside of Abbeville, Northern France, Darren Parris, Tom Blacker and Peter Parker from the International Aquafeed team, spent an afternoon late last year visiting trout farms. Our hosts were Phillip Jorgensen, fish farms manager, and Aubert Faivre, who is sales manager for Faivre.
The Salmonidae family, collectively known as Salmonids, comprises of salmon, trout, chars, freshwater whitefishes, and graylings, but it is the trout and Atlantic salmon, of the genus Salmo, which gives the family their name. A slender teleost fish, they can range in size between just 13 cm to a whopping 2 m in length. With a single row of sharp teeth, Salmonids are predators, choosing to feed on smaller fish, aquatic insects and small crustaceans. Despite spawning in fresh water Salmonids are mostly anadromous, spending their lives at sea, choosing only to return to rivers to reproduce.
Innovation nation - How new developments in aquaculture are boosting the Scot...International Aquafeed
With an estimated market value of over £1.8 billion and Scottish salmon exports alone reaching over £500 million, Scotland’s aquaculture sector is fast becoming a core pillar for the future growth of the Scottish economy. However, with such a steep increase in the demand for fish products, there is a real need for innovation within the sector to stay ahead of the curve and provide a sustainable supply of healthy protein; not only for the present but for the future of a market that appears set to keep growing. Ahead of Aquaculture UK, CEO of the Scottish Aquaculture Innovation Centre (SAIC), Heather Jones, shares some of the organisation’s forays into finfish research projects and the ways in which is working with both industry and academia to enhance the whole of the Scottish aquaculture sector.
The Asian catfish Pangasius, Pangasianodon hypophthalmus is recognised as a leading aquaculture food fish on world markets. The commercial culture of Pangasius was developed in the mid 1990’s in Vietnam and quickly expanded to production levels of nearly one million tons per year. Other countries including Thailand, Cambodia, Myanmar, Indonesia, Philippines, Bangladesh and India have adapted Pangasius as part of their aquaculture production. Pangasius can be successfully cultured in most tropical regions of the world however countries in the Western Hemisphere have been slow to embrace Pangasius aquaculture, in part, due to the lack of practical knowledge of the species food requirements during the larval and fry stages.
Mud crabs, also known as mangrove crabs, occur widely in estuaries and along tropical, subtropical and warm temperate coasts in the world. There are four species of mud crab (Family: Portunidae), Scylla serrata, S. tranquebarica, S. paramamosain and S. olivacea that are the focus of both commercial fisheries and aquaculture production throughout their distribution. They are among the most valuable crab species in the world, with the bulk of their commercial production sent live to market.
The European lobster (Homarus gammarus) is an ecologically important species of the North-eastern Atlantic which supports wild trap fisheries that are worth around £30 million each year to the UK alone. By weight the species is the highest-value seafood among those landed regularly in the UK and Ireland, where 75 percent of the ~5,000t annual landings for the species are made. As such, lobsters provide essential diversity to fragile inshore fisheries and vital income for rural coastal economies. However, populations across its range are pressured by rising exploitation, from which traditional fisheries management has failed to prevent extensive regional stock collapses in the recent past, and now struggles to stimulate recovery. While lobsters have long been transported as a live export commodity, chiefly to France and the Iberian peninsula, emerging markets, particularly those in East Asia, threaten to create additional demand for the species which far exceeds current capture yields. Improvements in hatchery rearing success have seen a number of recent aquaculture initiatives employed, in the hope of both generating restoration and improved sustainability of wild harvests, and instigating commercial aquaculture possibilities.
In the past 50 years, the global demand for fish products has doubled, and more than 45 percent of the world’s seafood today now comes not from wild catches, but from either land-based or offshore fish farms. To meet this rising demand for seafood worldwide, more fish have to be raised in fish farms, and aquaculture is an essential link in the agricultural chain.
When farming animals and fish, there is often a danger that we may assume that their dietary requirements match our own. However, those of the common carp, Cyprinus carpio, certainly do not.
Mexico, with a population of 122 million is the most populous Spanish-speaking country in the world. The country is known for its Pacific and Gulf of Mexico beaches and its diverse landscape of mountains, deserts and jungles. Ancient ruins such as Teotihuacan (Aztec), Chichen Itza (Mayan) and Spanish colonial-era towns are scattered throughout the country.
The quality and digestibility of proteins is one of the most important issues in shrimp nutrition. Marine proteins (mainly fish meal) can only be partially replaced by standard vegetable proteins like soybean meal.
KRILL OIL: Phospholipids that make a difference to filet quality and quantityInternational Aquafeed
The nutritional quality of larvae diets affects fishes’ fillet quality and quantity. Studies show that phospholipids increase fish larvae growth and development; so phospholipids are an essential component of the early weaning diet.
Carbohydrates are an excellent source of energy and carbon in feed formulations. They can be easily distinguished from the other energy yielding nutrients in terms of their abundance and low price. To illustrate, the collective global production of the major cereal grains i.e., maize, wheat and rice amounted to a colossal 2.5 billion tonnes in the year 2013 (FAO). The total carbohydrate content and the digestible fraction of starch and sugars in these grains can be roughly estimated to be about 2.1 and 1.75 billion tonnes, respectively (www.feedipedia.org). Besides, the unit cost of carbohydrate sources is almost three to five fold less than that of the protein and lipid sources of interest. Therefore, the inclusion level of carbohydrates in commercial fish feed assumes direct economic significance i.e., in terms of lower feed cost per unit weight gain.
Brewers' yeast and its derivatives have been used successfully in animal nutrition for decades. Leiber GmbH produces brewers' yeast products from their facilities in Germany, Poland, and Russia. Brewers' yeast is a high-quality byproduct of the beer brewing process, which is strictly regulated in Germany. Leiber produces various yeast derivatives for animal feed through processing, including inactivated yeast, autolyzed yeast with broken cell walls for improved nutrient availability, yeast cell walls containing beneficial glucans and mannans, and highly purified beta-glucans. These products provide nutrients, support immune function, and aid digestion when included in animal and aquaculture feeds.
FISH FARMING TECHNOLOGY - Efficient and reliable feed system for fish farming...International Aquafeed
The main purpose of a feed barge is to provide an efficient and reliable feed system for fish farming operations. The second purpose is to provide a safe worksite for operators.
FISH FARMING TECHNOLOGY - Light Emitting Diode (LED) Lighting systems for ear...International Aquafeed
Over recent times we have noticed an increasing amount of media coverage and industry chatter regarding the role of light in aquaculture. Most of this has been in relation to the use of low-energy technology to reduce costs, and in this area almost all the talk is about LED
The Latin names of some aquatic species can have fascinatingly obscure meanings that provide anyone in need of a hobby with hours of joyful investigation and speculation. The channel catfish is, alas, not one of them: Ictalurus punctatus simply means ‘spotty catfish’, and the briefest glance at one will tell you why.
It is often thought that vacuum coating was firs t invented in Norway. The idea might have been Norwegian, but the technology was developed in the Netherlands. It has been 25 years now since Dinnissen, together with aquafeed producer Skretting, invented the firs t vacuum coater.
The Pegasus® Vacuum Coater is intended for everyone who wishes to manufacture pelleted and extruded products in accordance with mos t modern production specifications.
It allows you to create a vacuum environment for your production process and to deal effectively with a very wide range of future challenges.
International Aquafeed spoke to Peter Raeven, Account Manager for Dinnissen, about the previous 25 years of the Pegasus® Vacuum Coater as well as any future plans that Dinnissen might have for their now well es tablished brand.
As an aquafeed processor, you are always aware that your drying operation has a significant impact on your bottom line. Drying is a very energy-intensive operation; that’s why most aquafeed producers diligently track the cost of fuel used in their drying operation.
As an aquafeed processor, you are always aware that your drying operation has a significant impact on your bottom line. Drying is a very energy-intensive operation; that’s why most aquafeed producers diligently track the cost of fuel used in their drying operation.
Much has been made of gut health recently. By unpacking the concept, we can arrive at a better understanding of the driving factors, influences, indicators and implications of gut health for aquaculture.
Dr. Eckel – Germany’s pioneer in functional feed additives – is constantly working on new solutions to provide reliable solutions for premium aquaculture feed. Dr. Eckel now releases Anta®Ox Aqua – the all-natural feed additive for intensive Shrimp production.
Cottonseed protein has great potential to replace fishmeal in aquaculture feeds. It provides a sustainable, plant-based protein source that is comparable to fishmeal in amino acid profile and highly palatable to aquatic species. While cottonseed contains the toxin gossypol, some aquatic species like catfish and shrimp are quite tolerant. Glandless cotton varieties that are gossypol-free are being grown experimentally and could be scaled up. Transgenic technology may also soon produce ultra-low gossypol cottonseeds. Cottonseed protein is available now and can partially or fully replace fishmeal in many aquaculture diets depending on the species' gossypol tolerance. This has the potential to significantly improve aquaculture
The document provides details about Bibury Trout Farm, one of Britain's oldest trout farms. It discusses the farm's founding in 1902 to stock local rivers, and describes the current focus of restocking rivers and streams. It then summarizes the hatchery tour, explaining the GlobalGAP certification process, triploidization of eggs to produce sterile female fish, and incubation and hatching of eggs. The summary highlights the farm's emphasis on sustainable practices and tourism.
When we think about Brazil, the first thing we have in mind is happy people, carnivals and one of the top beef cattle and soybean producers globally. However, it seems that the taste or the way Brazilians perceive fish, one of the healthiest protein sources available, has been changing nowadays.
In the past 50 years, the global demand for fish products has doubled, and more than 45 percent of the world’s seafood today now comes not from wild catches, but from either land-based or offshore fish farms. To meet this rising demand for seafood worldwide, more fish have to be raised in fish farms, and aquaculture is an essential link in the agricultural chain.
When farming animals and fish, there is often a danger that we may assume that their dietary requirements match our own. However, those of the common carp, Cyprinus carpio, certainly do not.
Mexico, with a population of 122 million is the most populous Spanish-speaking country in the world. The country is known for its Pacific and Gulf of Mexico beaches and its diverse landscape of mountains, deserts and jungles. Ancient ruins such as Teotihuacan (Aztec), Chichen Itza (Mayan) and Spanish colonial-era towns are scattered throughout the country.
The quality and digestibility of proteins is one of the most important issues in shrimp nutrition. Marine proteins (mainly fish meal) can only be partially replaced by standard vegetable proteins like soybean meal.
KRILL OIL: Phospholipids that make a difference to filet quality and quantityInternational Aquafeed
The nutritional quality of larvae diets affects fishes’ fillet quality and quantity. Studies show that phospholipids increase fish larvae growth and development; so phospholipids are an essential component of the early weaning diet.
Carbohydrates are an excellent source of energy and carbon in feed formulations. They can be easily distinguished from the other energy yielding nutrients in terms of their abundance and low price. To illustrate, the collective global production of the major cereal grains i.e., maize, wheat and rice amounted to a colossal 2.5 billion tonnes in the year 2013 (FAO). The total carbohydrate content and the digestible fraction of starch and sugars in these grains can be roughly estimated to be about 2.1 and 1.75 billion tonnes, respectively (www.feedipedia.org). Besides, the unit cost of carbohydrate sources is almost three to five fold less than that of the protein and lipid sources of interest. Therefore, the inclusion level of carbohydrates in commercial fish feed assumes direct economic significance i.e., in terms of lower feed cost per unit weight gain.
Brewers' yeast and its derivatives have been used successfully in animal nutrition for decades. Leiber GmbH produces brewers' yeast products from their facilities in Germany, Poland, and Russia. Brewers' yeast is a high-quality byproduct of the beer brewing process, which is strictly regulated in Germany. Leiber produces various yeast derivatives for animal feed through processing, including inactivated yeast, autolyzed yeast with broken cell walls for improved nutrient availability, yeast cell walls containing beneficial glucans and mannans, and highly purified beta-glucans. These products provide nutrients, support immune function, and aid digestion when included in animal and aquaculture feeds.
FISH FARMING TECHNOLOGY - Efficient and reliable feed system for fish farming...International Aquafeed
The main purpose of a feed barge is to provide an efficient and reliable feed system for fish farming operations. The second purpose is to provide a safe worksite for operators.
FISH FARMING TECHNOLOGY - Light Emitting Diode (LED) Lighting systems for ear...International Aquafeed
Over recent times we have noticed an increasing amount of media coverage and industry chatter regarding the role of light in aquaculture. Most of this has been in relation to the use of low-energy technology to reduce costs, and in this area almost all the talk is about LED
The Latin names of some aquatic species can have fascinatingly obscure meanings that provide anyone in need of a hobby with hours of joyful investigation and speculation. The channel catfish is, alas, not one of them: Ictalurus punctatus simply means ‘spotty catfish’, and the briefest glance at one will tell you why.
It is often thought that vacuum coating was firs t invented in Norway. The idea might have been Norwegian, but the technology was developed in the Netherlands. It has been 25 years now since Dinnissen, together with aquafeed producer Skretting, invented the firs t vacuum coater.
The Pegasus® Vacuum Coater is intended for everyone who wishes to manufacture pelleted and extruded products in accordance with mos t modern production specifications.
It allows you to create a vacuum environment for your production process and to deal effectively with a very wide range of future challenges.
International Aquafeed spoke to Peter Raeven, Account Manager for Dinnissen, about the previous 25 years of the Pegasus® Vacuum Coater as well as any future plans that Dinnissen might have for their now well es tablished brand.
As an aquafeed processor, you are always aware that your drying operation has a significant impact on your bottom line. Drying is a very energy-intensive operation; that’s why most aquafeed producers diligently track the cost of fuel used in their drying operation.
As an aquafeed processor, you are always aware that your drying operation has a significant impact on your bottom line. Drying is a very energy-intensive operation; that’s why most aquafeed producers diligently track the cost of fuel used in their drying operation.
Much has been made of gut health recently. By unpacking the concept, we can arrive at a better understanding of the driving factors, influences, indicators and implications of gut health for aquaculture.
Dr. Eckel – Germany’s pioneer in functional feed additives – is constantly working on new solutions to provide reliable solutions for premium aquaculture feed. Dr. Eckel now releases Anta®Ox Aqua – the all-natural feed additive for intensive Shrimp production.
Cottonseed protein has great potential to replace fishmeal in aquaculture feeds. It provides a sustainable, plant-based protein source that is comparable to fishmeal in amino acid profile and highly palatable to aquatic species. While cottonseed contains the toxin gossypol, some aquatic species like catfish and shrimp are quite tolerant. Glandless cotton varieties that are gossypol-free are being grown experimentally and could be scaled up. Transgenic technology may also soon produce ultra-low gossypol cottonseeds. Cottonseed protein is available now and can partially or fully replace fishmeal in many aquaculture diets depending on the species' gossypol tolerance. This has the potential to significantly improve aquaculture
The document provides details about Bibury Trout Farm, one of Britain's oldest trout farms. It discusses the farm's founding in 1902 to stock local rivers, and describes the current focus of restocking rivers and streams. It then summarizes the hatchery tour, explaining the GlobalGAP certification process, triploidization of eggs to produce sterile female fish, and incubation and hatching of eggs. The summary highlights the farm's emphasis on sustainable practices and tourism.
When we think about Brazil, the first thing we have in mind is happy people, carnivals and one of the top beef cattle and soybean producers globally. However, it seems that the taste or the way Brazilians perceive fish, one of the healthiest protein sources available, has been changing nowadays.
Digital Banking in the Cloud: How Citizens Bank Unlocked Their MainframePrecisely
Inconsistent user experience and siloed data, high costs, and changing customer expectations – Citizens Bank was experiencing these challenges while it was attempting to deliver a superior digital banking experience for its clients. Its core banking applications run on the mainframe and Citizens was using legacy utilities to get the critical mainframe data to feed customer-facing channels, like call centers, web, and mobile. Ultimately, this led to higher operating costs (MIPS), delayed response times, and longer time to market.
Ever-changing customer expectations demand more modern digital experiences, and the bank needed to find a solution that could provide real-time data to its customer channels with low latency and operating costs. Join this session to learn how Citizens is leveraging Precisely to replicate mainframe data to its customer channels and deliver on their “modern digital bank” experiences.
How information systems are built or acquired puts information, which is what they should be about, in a secondary place. Our language adapted accordingly, and we no longer talk about information systems but applications. Applications evolved in a way to break data into diverse fragments, tightly coupled with applications and expensive to integrate. The result is technical debt, which is re-paid by taking even bigger "loans", resulting in an ever-increasing technical debt. Software engineering and procurement practices work in sync with market forces to maintain this trend. This talk demonstrates how natural this situation is. The question is: can something be done to reverse the trend?
5th LF Energy Power Grid Model Meet-up SlidesDanBrown980551
5th Power Grid Model Meet-up
It is with great pleasure that we extend to you an invitation to the 5th Power Grid Model Meet-up, scheduled for 6th June 2024. This event will adopt a hybrid format, allowing participants to join us either through an online Mircosoft Teams session or in person at TU/e located at Den Dolech 2, Eindhoven, Netherlands. The meet-up will be hosted by Eindhoven University of Technology (TU/e), a research university specializing in engineering science & technology.
Power Grid Model
The global energy transition is placing new and unprecedented demands on Distribution System Operators (DSOs). Alongside upgrades to grid capacity, processes such as digitization, capacity optimization, and congestion management are becoming vital for delivering reliable services.
Power Grid Model is an open source project from Linux Foundation Energy and provides a calculation engine that is increasingly essential for DSOs. It offers a standards-based foundation enabling real-time power systems analysis, simulations of electrical power grids, and sophisticated what-if analysis. In addition, it enables in-depth studies and analysis of the electrical power grid’s behavior and performance. This comprehensive model incorporates essential factors such as power generation capacity, electrical losses, voltage levels, power flows, and system stability.
Power Grid Model is currently being applied in a wide variety of use cases, including grid planning, expansion, reliability, and congestion studies. It can also help in analyzing the impact of renewable energy integration, assessing the effects of disturbances or faults, and developing strategies for grid control and optimization.
What to expect
For the upcoming meetup we are organizing, we have an exciting lineup of activities planned:
-Insightful presentations covering two practical applications of the Power Grid Model.
-An update on the latest advancements in Power Grid -Model technology during the first and second quarters of 2024.
-An interactive brainstorming session to discuss and propose new feature requests.
-An opportunity to connect with fellow Power Grid Model enthusiasts and users.
HCL Notes und Domino Lizenzkostenreduzierung in der Welt von DLAUpanagenda
Webinar Recording: https://www.panagenda.com/webinars/hcl-notes-und-domino-lizenzkostenreduzierung-in-der-welt-von-dlau/
DLAU und die Lizenzen nach dem CCB- und CCX-Modell sind für viele in der HCL-Community seit letztem Jahr ein heißes Thema. Als Notes- oder Domino-Kunde haben Sie vielleicht mit unerwartet hohen Benutzerzahlen und Lizenzgebühren zu kämpfen. Sie fragen sich vielleicht, wie diese neue Art der Lizenzierung funktioniert und welchen Nutzen sie Ihnen bringt. Vor allem wollen Sie sicherlich Ihr Budget einhalten und Kosten sparen, wo immer möglich. Das verstehen wir und wir möchten Ihnen dabei helfen!
Wir erklären Ihnen, wie Sie häufige Konfigurationsprobleme lösen können, die dazu führen können, dass mehr Benutzer gezählt werden als nötig, und wie Sie überflüssige oder ungenutzte Konten identifizieren und entfernen können, um Geld zu sparen. Es gibt auch einige Ansätze, die zu unnötigen Ausgaben führen können, z. B. wenn ein Personendokument anstelle eines Mail-Ins für geteilte Mailboxen verwendet wird. Wir zeigen Ihnen solche Fälle und deren Lösungen. Und natürlich erklären wir Ihnen das neue Lizenzmodell.
Nehmen Sie an diesem Webinar teil, bei dem HCL-Ambassador Marc Thomas und Gastredner Franz Walder Ihnen diese neue Welt näherbringen. Es vermittelt Ihnen die Tools und das Know-how, um den Überblick zu bewahren. Sie werden in der Lage sein, Ihre Kosten durch eine optimierte Domino-Konfiguration zu reduzieren und auch in Zukunft gering zu halten.
Diese Themen werden behandelt
- Reduzierung der Lizenzkosten durch Auffinden und Beheben von Fehlkonfigurationen und überflüssigen Konten
- Wie funktionieren CCB- und CCX-Lizenzen wirklich?
- Verstehen des DLAU-Tools und wie man es am besten nutzt
- Tipps für häufige Problembereiche, wie z. B. Team-Postfächer, Funktions-/Testbenutzer usw.
- Praxisbeispiele und Best Practices zum sofortigen Umsetzen
Skybuffer SAM4U tool for SAP license adoptionTatiana Kojar
Manage and optimize your license adoption and consumption with SAM4U, an SAP free customer software asset management tool.
SAM4U, an SAP complimentary software asset management tool for customers, delivers a detailed and well-structured overview of license inventory and usage with a user-friendly interface. We offer a hosted, cost-effective, and performance-optimized SAM4U setup in the Skybuffer Cloud environment. You retain ownership of the system and data, while we manage the ABAP 7.58 infrastructure, ensuring fixed Total Cost of Ownership (TCO) and exceptional services through the SAP Fiori interface.
Taking AI to the Next Level in Manufacturing.pdfssuserfac0301
Read Taking AI to the Next Level in Manufacturing to gain insights on AI adoption in the manufacturing industry, such as:
1. How quickly AI is being implemented in manufacturing.
2. Which barriers stand in the way of AI adoption.
3. How data quality and governance form the backbone of AI.
4. Organizational processes and structures that may inhibit effective AI adoption.
6. Ideas and approaches to help build your organization's AI strategy.
Essentials of Automations: Exploring Attributes & Automation ParametersSafe Software
Building automations in FME Flow can save time, money, and help businesses scale by eliminating data silos and providing data to stakeholders in real-time. One essential component to orchestrating complex automations is the use of attributes & automation parameters (both formerly known as “keys”). In fact, it’s unlikely you’ll ever build an Automation without using these components, but what exactly are they?
Attributes & automation parameters enable the automation author to pass data values from one automation component to the next. During this webinar, our FME Flow Specialists will cover leveraging the three types of these output attributes & parameters in FME Flow: Event, Custom, and Automation. As a bonus, they’ll also be making use of the Split-Merge Block functionality.
You’ll leave this webinar with a better understanding of how to maximize the potential of automations by making use of attributes & automation parameters, with the ultimate goal of setting your enterprise integration workflows up on autopilot.
Connector Corner: Seamlessly power UiPath Apps, GenAI with prebuilt connectorsDianaGray10
Join us to learn how UiPath Apps can directly and easily interact with prebuilt connectors via Integration Service--including Salesforce, ServiceNow, Open GenAI, and more.
The best part is you can achieve this without building a custom workflow! Say goodbye to the hassle of using separate automations to call APIs. By seamlessly integrating within App Studio, you can now easily streamline your workflow, while gaining direct access to our Connector Catalog of popular applications.
We’ll discuss and demo the benefits of UiPath Apps and connectors including:
Creating a compelling user experience for any software, without the limitations of APIs.
Accelerating the app creation process, saving time and effort
Enjoying high-performance CRUD (create, read, update, delete) operations, for
seamless data management.
Speakers:
Russell Alfeche, Technology Leader, RPA at qBotic and UiPath MVP
Charlie Greenberg, host
zkStudyClub - LatticeFold: A Lattice-based Folding Scheme and its Application...Alex Pruden
Folding is a recent technique for building efficient recursive SNARKs. Several elegant folding protocols have been proposed, such as Nova, Supernova, Hypernova, Protostar, and others. However, all of them rely on an additively homomorphic commitment scheme based on discrete log, and are therefore not post-quantum secure. In this work we present LatticeFold, the first lattice-based folding protocol based on the Module SIS problem. This folding protocol naturally leads to an efficient recursive lattice-based SNARK and an efficient PCD scheme. LatticeFold supports folding low-degree relations, such as R1CS, as well as high-degree relations, such as CCS. The key challenge is to construct a secure folding protocol that works with the Ajtai commitment scheme. The difficulty, is ensuring that extracted witnesses are low norm through many rounds of folding. We present a novel technique using the sumcheck protocol to ensure that extracted witnesses are always low norm no matter how many rounds of folding are used. Our evaluation of the final proof system suggests that it is as performant as Hypernova, while providing post-quantum security.
Paper Link: https://eprint.iacr.org/2024/257
Introduction of Cybersecurity with OSS at Code Europe 2024Hiroshi SHIBATA
I develop the Ruby programming language, RubyGems, and Bundler, which are package managers for Ruby. Today, I will introduce how to enhance the security of your application using open-source software (OSS) examples from Ruby and RubyGems.
The first topic is CVE (Common Vulnerabilities and Exposures). I have published CVEs many times. But what exactly is a CVE? I'll provide a basic understanding of CVEs and explain how to detect and handle vulnerabilities in OSS.
Next, let's discuss package managers. Package managers play a critical role in the OSS ecosystem. I'll explain how to manage library dependencies in your application.
I'll share insights into how the Ruby and RubyGems core team works to keep our ecosystem safe. By the end of this talk, you'll have a better understanding of how to safeguard your code.
Discover top-tier mobile app development services, offering innovative solutions for iOS and Android. Enhance your business with custom, user-friendly mobile applications.
Driving Business Innovation: Latest Generative AI Advancements & Success StorySafe Software
Are you ready to revolutionize how you handle data? Join us for a webinar where we’ll bring you up to speed with the latest advancements in Generative AI technology and discover how leveraging FME with tools from giants like Google Gemini, Amazon, and Microsoft OpenAI can supercharge your workflow efficiency.
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2. Innovations for a better world.
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3. N
owadays, all animal production
is concerned with vaccination.
This is an essential technique
for the protection of livestock
health which, however, entails significant
costs for stock breeders. Maximizing the
efficiency and profitability of prophylactic
vaccination strategies is therefore a major
stake. To achieve this, new avenues are
constantly explored. One of these concerns
is the use of new molecules extracted from
seaweeds to help optimize the stimulation
of the natural defences of the body and its
response to vaccination strategies.
Innate immunity
The body’s response to the aggression of a
pathogen is based on two types of immunity.
They are the innate immune response and the
adaptive response.
The innate response is the first line of
defence against pathogens. It is activated
immediately and acts very quickly. This
immune response can be found in all ani-
mals. It will be the same whenever the
body encounters that pathogen. However,
the body does not retain a memory of the
infectious agent. The mechanism of action of
this type of immunity consists in recognizing
the molecular patterns shared by numerous
pathogens, which are essentially represented
by membrane fractions (glycocalyx).
The various elements that contribute to
the innate immune response are the following:
• Physical barrier (mucous membrane,
skin, mucus, villi etc)
• Phagocytic cells, such as the macrophages
• Natural killer (NK) cells
• Certain cytokines, which deliver signals
warning the body of a danger
• Complement system
• Toll-like receptors (TLR), a family of
membrane receptors only discovered
recently. They control the expression
of molecules that fight against infectious
agents (directly or indirectly, via effector
cells, and by recruiting the activation of
the adaptive immune system).
The elements associated with the innate
immune response can act on the pathogen
directly or indirectly, by producing effector
cells (cytokines etc). The latter will subse-
quently trigger the adaptive immunity by
activating the T and B cells.
Adaptive immunity
Unlike the innate response, the acquired or
adaptive response occurs in vertebrates only.
During the first encounter with a given patho-
gen (primary infection), it acts as the body’s
second line of defence. Its activation takes
some time - known as latency. However, this
response system memorizes the pathogens
it encounters and when the body is again
exposed to them the latency is much shorter
and the immune system reacts to the aggres-
sion almost immediately. Adaptive immunity
is specific: it recognises the molecular patterns
of the already encountered pathogens.
The various elements that contribute to
the adaptive immune response are the fol-
lowing:
• T cells
• B cells
• Antibodies
• Ig, TCR, CTL, antibody (AB)-producing
plasma cells + coupled aid of the innate
immunity effectors
Seaweeds: a new source of
active elements to stimulate
the immune system
In recent years more and more publica-
tions have brought to the forefront the
relevance of seaweeds in numerous biological
applications, particularly to immune mecha-
nisms, taking special interest in some of their
components, namely the sulfated polysac-
Marine algal polysaccharides:
a new option for immune stimulation
18 | InternatIOnal AquAFeed | September-October 2013
FEATURE
NK : Natural Killer
PRR : Pattern Recognition Receptor
CMH : Complexe Majeur d’histocompatibilité
TCP : T Cell Receptor
4.
5. charides. These are complex carbohydrates
which do not occur in terrestrial plants. They
are supposed to influence the immune system
by a vast number of still poorly understood
pathways.
Polysaccharides represent a structurally
diverse class of macromolecules which are
relatively widespread in nature. There are
simple and complex forms of polysachharides.
Unlike proteins and nucleic acids, polysac-
charides contain repetitive structural features
which are chains of monosaccharide residues
joined together by glycosidic bonds.
Thus, they form polymer (-type) structures
represented in the form of chains that may be
homogenous (homopolysaccharides) or not
(heteropolysaccharides). The simple forms
are the homopolysac-
charides composed of
a single type of sugar,
linked in an essentially
linear manner (starch,
glycogen, cellulose for
example). They are
essentially structural
compounds or mecha-
nisms of energy storage
in an easily releasable
form. Their structure
may become more
complex owing to their capacity to
establish links at various levels of each
elementary unit, allowing thus the
development of branching structures
in the three dimensions. These are the
branched heteropolysaccharides.
Structural variability and
biological potentialities
The nucleotides in nucleic acids and
the amino acids in proteins can inter-
connect in only one way, while the
monosaccharide units in oligosaccha-
rides and polysaccharides can intercon-
nect at several points to form a wide
variety of linear or branched structures
(Sharon and Lis 1993). For instance,
the number of possible permutations for
four different sugar monomers can attain
September-October 2013 | InternatIOnal AquAFeed | 19
FEATURE
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Innate immunity / acquired immunity: two complementary and cooperative systems
Innate immunity adaptive or acquired immunity
Chronology
Primary infection
Quick response: first
barrier against pathogens
Second line of defence : latency
(about 7 days)
repeated infections
Identical to the primary
response
Immune memory => latency
close to zero
Specificity non-specific response Specific response (Ig and tCr)
recognized molecular patterns
Invariable and common to
numerous pathogens
Specific to the infectious agent
Cellular and molecular effectors
Complement, phagocytic
cells and certain cytokines
Ctl (cytotoxic t cells) and anti-
body producing plasma cells,
with the help of innate effectors
tCr : t Cell receptor - Ig : Immuno Globulin - Ctl : Cytotoxic t lymphocyte or Killer t cells
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7. up to 35,560 unique tetrasaccharides, while
four amino acids can form only 24 different
permutations (Hodgson 1991).
This explains the fact that, among macro-
molecules, polysaccharides provide the high-
est capacity for carrying biological informa-
tion, as they have the greatest potential for
structural variability. In addition, one of the
particularities that numerous marine polysac-
charides possess is their polyanionic character,
which confers them a high chemical reactivity.
Of these anionic polysaccharides, the
majority of those which occur macroalgae
are sulfated polysaccharides: galactan (agar,
carraghenans), ulvans, fucans.
The ulvans, for example, the water-soluble
polysaccharides found in green seaweed of
the order Ulvales (Ulva and Enteromorpha),
have sulfate, rhamnose, xylose and iduronic
and glucuronic acids as their main constitu-
ents (Lahaye and Ray 1996) (Percival and
McDowell 1967).
Ulvan structure shows great complexity
and variability as evidenced by the numerous
oligosaccharide repeating structural patterns
identified (Lahaye and Robic 2007). The main
repeating disaccharide units reported are of
ulvanobiouronic acid 3-sulfate type, containing
either glucuronic or iduronic acid. In addition,
a few repeating patterns can be found that
contain sulfated xylose replacing uronic acid
or glucuronic acid on the O-2 binding/link of
the rhamnose-3-sulfate units (Lahaye and Ray
1996) (Lahaye et al. 1997).
Interests
This huge variability in the polysaccharide
structure provides the flexibility required for
exact regulatory mechanisms in different cell-
cell interactions in higher organisms.
Sulfation in particular seems to be con-
ducive to various biological activities noted
in polysaccharides extracted from marine
macroalgae.
Marine sulfated polysaccharides:
their role and effect on immunity
Sulfated polysaccharides, which are wide-
spread in macroalgae, have been shown
to possess anti-infectious (Cumashi et al.
2007) (Witvrouw and De Clercq 1997) (anti-
viral, anti-bacterial, anti-tumoral), antioxidant
(Wang et al. 2010) (de Souza et al. 2007) and
anti-thrombotic (Mao et al. 2006) activities,
as well as immune-modulating (Leiro et al.
2007) activities that might find relevance in
stimulating the immune response or in con-
trolling the activity of immune cells in order to
mitigate negative effects such as inflammation
(Chen et al. 2008) One of the pathways of
marine sulfated polysaccharides, which has
been emphasized recently, is their role in the
activation of TLR.
Indeed, more and more studies are demon-
strating that marine algal polysaccharides can influ-
ence the innate immune response by binding to
recognition receptors called Pattern Recognition
Receptorsc (PRR), such as the mannose recep-
tors or TLRs of phagocytic cells, including and
especially macrophages (Chen et al. 2008). TLRs
are transmembrane proteins which detect invad-
ing pathogens by binding to ancestral molecules
of microbial origin called Pathogen-Associated
Molecular Patterns (PAMPs).
The PAMPs contact at TRL level triggers a
cascade of responses resulting in the expres-
sion of inflammatory response genes. In mam-
mals, these recently identified receptors have
been numbered from 1 to 11 (TLR1-TLR11).
On contact with their
respective PAMPs,
TLR specifically acti-
vate a signaling path-
way leading to the
activation of NF-kB
(Nuclear Factor-
kappa B) and AP1
(ActivatorProtein
1) transcription fac-
tors regulating the
expression of inflam-
matory cytokines
such as TNFα, IL-1
or IL-6.
It therefore now
20 | InternatIOnal AquAFeed | September-October 2013
FEATURE
Structure of the 4 main repeating ulvan
patterns of Ulva lactuca
Ulvanobiouronic acid A. [→ 4)-β-D-
GlcA-(1 → 4)-α-L-Rha3S-(1 →] n;
Ulvanobiouronic acid B. [→ 4) - α-L-
IdoA-(1 → 4)-α-L-Rha3S-(1 →] n
Ulvanobiose A. [→ 4)-β-D- Xyl -(1 →
4)-α-L-Rha3S-(1 →] n;
Ulvanobiose B. [→ 4)-β-D- Xyl 2S-(1 →
4)-α-L-Rha3S-(1 →] n;
Classification of Marine Sulfated
Polysaccharides (MSP)
Branched sulfated
heteropolysaccharide
8. appears that TLR play a key role in the
adaptive immune response, but the signals
produced by their activation lead to the
activation of numerous other cells and func-
tions of the immune system, which makes
them essential elements of both the innate
immune mechanisms and of adaptive immu-
nity.
The activity of some sulfated algal polysac-
charides as TLR activating agents might be
the result of a certain structural similarity
between these marine polysaccharides and
bacterial lipopolysaccharides (LPS). Bacterial
LPSs are indeed a type of structure occurring
at the surface of their external membrane
and recognized as bacteria-specific recognition
elements. In particular, bacterial LPS in mam-
mals are shown to be specifically recognised
by TLR4.
Possible applications
in animal health
In conclusion, seaweeds appear to contain
sugars in the form of polysaccharides, some of
which - sulfated polysaccharides - are complex
polyanionic structures which possess various
biological properties. A vast number of studies
have already evidenced the effects of some of
these sulfated polysaccharides, particularly the
fucoidans, the carraghenans and the ulvans, on
certain mechanisms of inflammatory response
and on immunity.
The identification and selection of these
polysaccharides extracted from suitable
macroalgae makes it possible to envisage
the use of these molecules as agents for
the stimulation of the various mechanisms
associated with the body defence and, in
particular, of the innate immunity mecha-
nisms.
Within the framework of the potential
applications in the fields of animal breeding
and animal health two non-exclusive strategies
can be proposed:
Regular sequential intakes for a general
stimulation of the body’s state of defence:
• With a regular intake not connected
with vaccination, they allow the
strengthen-
ing of the
body’s state
of defence.
Repeated use
allows the
development
of a ‘basic’
immune sys-
tem and the
boosting of
the state of
defence of the
innate system.
The use of
polysaccha-
rides upstream
or downstream
of a prophylactic
programme may
be an asset in
enhancing the
level of immune
protection of
an individual or
group of indi-
viduals within a
livestock and in
contributing to
a better control
of the infectious
pressure on
the livestock,
preventing the
appearance of
recurrent infec-
tious pathologies.
Targeted intakes
within the framework
of a vaccination pro-
gramme:
• As part of a
vaccination pro-
gramme, they
would enhance
the vaccine
protection. This
would definitely
provide the pos-
sibility to improve
the intake and
persistence of the
vaccine and there-
by to improve
the technical and
economic per-
formance of vac-
cine prophylactic
programmes.
More InforMatIon:
Website:www.olmix.com
September-october 2013 | InternatIonal AquAFeed | 21
FEATURE
Sulfated
polysaccharide
Cytokine/Chemokine
production
9. www.aquafeed.co.uk
LINKS
• See the full issue
• Visit the International Aquafeed website
• Contact the International Aquafeed Team
• Subscribe to International Aquafeed
The potential of
microalgae meals
– in compound feeds for aquaculture
Understanding ammonia
in aquaculture ponds
Volume 16 Issue 5 2013 - sePTemBeR | oCToBeR
INCORPORATING
fIsh fARmING TeChNOlOGy
EXPERT TOPIC
– Salmon
AquaNor event review
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