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HUNTINGTON’S
DISEASE
People may experience:
Muscular: abnormality walking, increased muscle activity,
involuntary movements, problems with coordination, loss of
muscle, or muscle spasms
Cognitive: amnesia, delusion, lack of concentration, mental
confusion, slowness in activity, or difficulty thinking and
understanding
Behavioral: compulsive behavior, fidgeting, irritability, or lack
of restraint
Psychological: delirium, depression, hallucination, or paranoia
Mood: anxiety, apathy, or mood swings
Also common: difficulty speaking, memory loss, tremor, or
weight loss
What are the Symptoms?
• Movement in the arms, legs, head or other parts of the body that
you cannot control or stop (most common)
• Loss of memory or thinking skills
• Changes in mood (feeling annoyed, depressed, or anxious)
How is it Diagnosed?
• Huntington’s disease can be diagnosed through neurological,
psychological, and genetic testing.
• A neurologist is a doctor who treats disorders affecting the brain,
spinal cord, and nerves. They can rule out other conditions.
Can it be Treated?
Currently, there is no cure for Huntington’s disease. Treatment
includes managing the symptoms of the disease, which may include
medications to help manage mood or anxiety.
Have questions?
Ask your doctor or health care provider at your next appointment.
Created June 2020. Medically reviewed by Sharon Brangman, MD, FACP, AGSF
NIH Medline Plus. (2019). Huntington’s Disease. Retrieved from https://medlineplus.gov/huntingtonsdisease.html
Alzheimer’s Association (2020). Huntington’s Disease. Retrieved from https://www.alz.org/alzheimers-dementia/what-is-dementia/types-of-
dementia/huntington-s-disease
NIH National Institute of Neurological Disorders and Stroke. (2020). Huntington’s Disease: Hope Through Research. Retrieved from
https://www.ninds.nih.gov/disorders/patient-caregiver-education/hope-through-research/huntingtons-disease-hope-through
Osipovitch, M., Asenjo-Martinez, A., Mariani, J., Cornwell, A., Dhaliwal, S., Zou, L., Chandler-Militello, D., Wang, S., Li, X., Benraiss, S., Agate, R.,
Lampp, A., Benraiss, A., Windrem, M., & Goldman, S. (2019). Human ESC-derived chimeric mouse models of Huntington disease reveal cell-
intrinsic defects in glial progenitor cell differentiation. Cell Stem Cell. 24(1), 107-122.e7. hhtps://doi.org/10.1016/j.stem.2018.11.010
UR Medicine. (2020). Neurology at Highland Hospital. Retrieved from https://www.urmc.rochester.edu/highland/departments-
centers/neurology/what-is-a-neurologist.aspx

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huntingtons-disease.pptx

  • 2. People may experience: Muscular: abnormality walking, increased muscle activity, involuntary movements, problems with coordination, loss of muscle, or muscle spasms Cognitive: amnesia, delusion, lack of concentration, mental confusion, slowness in activity, or difficulty thinking and understanding Behavioral: compulsive behavior, fidgeting, irritability, or lack of restraint Psychological: delirium, depression, hallucination, or paranoia Mood: anxiety, apathy, or mood swings Also common: difficulty speaking, memory loss, tremor, or weight loss
  • 3. What are the Symptoms? • Movement in the arms, legs, head or other parts of the body that you cannot control or stop (most common) • Loss of memory or thinking skills • Changes in mood (feeling annoyed, depressed, or anxious)
  • 4. How is it Diagnosed? • Huntington’s disease can be diagnosed through neurological, psychological, and genetic testing. • A neurologist is a doctor who treats disorders affecting the brain, spinal cord, and nerves. They can rule out other conditions.
  • 5. Can it be Treated? Currently, there is no cure for Huntington’s disease. Treatment includes managing the symptoms of the disease, which may include medications to help manage mood or anxiety.
  • 6. Have questions? Ask your doctor or health care provider at your next appointment. Created June 2020. Medically reviewed by Sharon Brangman, MD, FACP, AGSF NIH Medline Plus. (2019). Huntington’s Disease. Retrieved from https://medlineplus.gov/huntingtonsdisease.html Alzheimer’s Association (2020). Huntington’s Disease. Retrieved from https://www.alz.org/alzheimers-dementia/what-is-dementia/types-of- dementia/huntington-s-disease NIH National Institute of Neurological Disorders and Stroke. (2020). Huntington’s Disease: Hope Through Research. Retrieved from https://www.ninds.nih.gov/disorders/patient-caregiver-education/hope-through-research/huntingtons-disease-hope-through Osipovitch, M., Asenjo-Martinez, A., Mariani, J., Cornwell, A., Dhaliwal, S., Zou, L., Chandler-Militello, D., Wang, S., Li, X., Benraiss, S., Agate, R., Lampp, A., Benraiss, A., Windrem, M., & Goldman, S. (2019). Human ESC-derived chimeric mouse models of Huntington disease reveal cell- intrinsic defects in glial progenitor cell differentiation. Cell Stem Cell. 24(1), 107-122.e7. hhtps://doi.org/10.1016/j.stem.2018.11.010 UR Medicine. (2020). Neurology at Highland Hospital. Retrieved from https://www.urmc.rochester.edu/highland/departments- centers/neurology/what-is-a-neurologist.aspx