How does myosin II differ from myosin V? Myosin II assembles into bipolar thick filaments to contract anti-parallel actin filaments whereas myosin V binds a membrane vesicle cargo with its tail and carries the cargo toward the plus end of a single actin filament. Myosin II walks on microtubules whereas myosin V walks on tubulin dimers. Myosin II walks on F -actin whereas myosin walks on g -actin. Myosin II assembles into bipolar thick filaments to contract anti- parallel microtubules whereas myosin V binds a membrane vesicle cargo with its tail and carries the cargo toward the plus end of a single microtubule. Question 5 1 pts GTP-rho activates: WASP which then binds and activates ARP2,3, which nucleates a branched network of F -actin, which pushes the plasma membrane forward by a thermal ratchet mechanism: Binding of importins to NLS (nuclear localization signal). Formins which nucleate straight actin filaments and rho kinase which activates myosin II by phosphorylating myosin regulatory light chain. Contraction of branched microtubule networks..