Holistic Education Dr
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Holistic education aims to facilitate physical, emotional, intellectual, and spiritual growth through practices like namasmarnan in order to promote well-being at the individual, group, national, and global levels. A piecemeal approach that focuses on petty pursuits under the guise of development has led to overproduction, excessive marketing, energy waste, pollution, and conditions that fuel terrorism. The lack of holistic education emphasizing an integrated approach is responsible for hype around value systems that promote these issues.
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Marathi, Mahatma Gandhi And Namasmaran Dr Shriniwas Kashalikar
1. Political leaders are trying to elevate themselves by promoting sectarian ideas around language and identity, while opponents disguise themselves as broad-minded.
2. As a common man, the author feels torn between protecting his self-respect and livelihood, and embracing a more unifying attitude.
3. The solution is for common people to rise above feelings of inadequacy or fear of others, and make efforts to grow together rather than reacting in a vicious manner.
Beware Of Meditation Dr Shriniwas Kashalikar
This document discusses the differences between meditation and Total Stress Management (TSM). It provides instructions for different meditation techniques but warns that people are often selling and buying meditation for petty reasons like stress management. TSM aims to understand and treat the root causes of stress in a holistic way through active intellectual efforts, whereas meditation focuses on temporary emotional relief. TSM also aims for the welfare of all through sound intellectual solutions, rather than just individual welfare. The concepts of TSM are still relatively new and not widely accepted or practiced due to various reasons like lack of conviction, delay in publishing information, and lack of popularity.
R E M E D I E S I F O U N D U S E F U L I N J O I N T P A I N S D R S...
Drinking 3-4 glasses of water in the morning on an empty stomach, drinking cow milk with dry ginger and turmeric, and taking fenugreek sprouted beans in the morning or evening can help with joint pains according to Dr. Shriniwas Kashalikar. He also recommends avoiding cold foods and drinks, eating chyavanaprash, gentle oil massages, breathing exercises, and practicing "superliving".
Is Meditation Harmful Dr Shriniwas Kashalikar
Meditation is not harmful, but is instead a natural stage of inner growth and blossoming that occurs through holistic personal and social development. [1] Proper meditation happens as a result of addressing physical, emotional, intellectual, and spiritual needs, and through implementing solutions to problems, similar to progressing through levels of education. [2] What some practice as "meditation" without this holistic growth can be harmful and cause misery. [3] True meditation is an evolved state achieved through actively working to solve individual and social issues, as taught in Total Stress Management.
WordPress in Business
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Исследование - 100 000 отзывов с упоминаниями городов Крыма
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Marathi, Mahatma Gandhi And Namasmaran Dr Shriniwas Kashalikar
1. Political leaders are trying to elevate themselves by promoting sectarian ideas around language and identity, while opponents disguise themselves as broad-minded.
2. As a common man, the author feels torn between protecting his self-respect and livelihood, and embracing a more unifying attitude.
3. The solution is for common people to rise above feelings of inadequacy or fear of others, and make efforts to grow together rather than reacting in a vicious manner.
Beware Of Meditation Dr Shriniwas Kashalikar
This document discusses the differences between meditation and Total Stress Management (TSM). It provides instructions for different meditation techniques but warns that people are often selling and buying meditation for petty reasons like stress management. TSM aims to understand and treat the root causes of stress in a holistic way through active intellectual efforts, whereas meditation focuses on temporary emotional relief. TSM also aims for the welfare of all through sound intellectual solutions, rather than just individual welfare. The concepts of TSM are still relatively new and not widely accepted or practiced due to various reasons like lack of conviction, delay in publishing information, and lack of popularity.
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Drinking 3-4 glasses of water in the morning on an empty stomach, drinking cow milk with dry ginger and turmeric, and taking fenugreek sprouted beans in the morning or evening can help with joint pains according to Dr. Shriniwas Kashalikar. He also recommends avoiding cold foods and drinks, eating chyavanaprash, gentle oil massages, breathing exercises, and practicing "superliving".
Is Meditation Harmful Dr Shriniwas Kashalikar
Meditation is not harmful, but is instead a natural stage of inner growth and blossoming that occurs through holistic personal and social development. [1] Proper meditation happens as a result of addressing physical, emotional, intellectual, and spiritual needs, and through implementing solutions to problems, similar to progressing through levels of education. [2] What some practice as "meditation" without this holistic growth can be harmful and cause misery. [3] True meditation is an evolved state achieved through actively working to solve individual and social issues, as taught in Total Stress Management.
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Holistic Education Dr
Holistic education aims to facilitate physical, emotional, intellectual, and spiritual growth to benefit individuals, groups, nations, and the world. It takes a holistic approach rather than focusing on petty pursuits or piecemeal development. A lack of holistic education has led to out-of-control industries that produce unnecessary products, consume resources, add to pollution, and promote an atmosphere conducive to terrorism. Namasmaran, or remembrance of God, is at the core of holistic education.
Stress and holistic health dr. shriniwas j. kashalikar
The document discusses holistic health and the need for holistic policies and approaches. It argues that the current education system fails to promote creativity and productivity. It also states that fulfilling all human needs in an appropriate way, such as through physical activity and social interaction, is essential for individual and social well-being. The document advocates for holistic medicine and non-restrictive laws to allow for holistic treatment. It suggests that regular remembrance of the divine (Namasmaran) can help enable holistic blossoming of individuals and society.
Stress and holistic_health_dr._shriniwas_j._kashalikar
The document discusses holistic health and the need for holistic policies and approaches. It argues that the current education system focuses too much on academics and not enough on creativity, productivity, and practical skills. This causes problems like unemployment, poverty, and lack of dignity in labor-oriented jobs. The document advocates for fulfilling all human needs - including physical, psychological, social, and intellectual - in a balanced way in order to achieve true well-being or "holistic health" for individuals and society. It also discusses the need for non-restrictive laws around holistic medical training and treatment approaches. NAMASMARAN, or remembering the divine name, is presented as a way to cultivate holistic perspectives and bloss
Holistic renaissance dr shriniwas kashalikar
The divisions such as spiritual, material, theist, atheist, superstitious, rationalist etc would begin to dissolve in common pursuit of HOLISTIC RENAISSANCE through the common minimum program of NAMASMARAN.
Holistic renaissance dr shriniwas kashalikar
HOLISTIC RENAISSANCE
HOLISTIC RENAISSANCE is the development of perspective, policies, plans, programs and implementation; of these for individual and global blossoming. The message of Geeta is; HOLISTIC RENAISSANCE is bound to manifest; through the life struggle (DHARMA YUDDHA) irrespective of whether we support it or oppose!
Health geeta and namasmaran dr shriniwas kashalikar
HEALTH GEETA AND NAMASMARAN
The divisions such as spiritual, material, theist, atheist, superstitious, rationalist etc would begin to dissolve in common pursuit of HOLISTIC RENAISSANCE through the common minimum program of NAMASMARAN.
T H E B U S I N E S S O F F E A R Dr
Insurance companies, medical businesses, and other industries generate and spread unfounded fear to promote their products and services. This fear-mongering has led people to avoid naturally occurring products like ghee, coconut oil, and salt in favor of alternative products, fueling business growth. However, exploiting public fear for financial gain undermines well-being and can have widespread health impacts. Spiritual practices like remembrance of God's name may help implement wiser policies focused on individual and global welfare rather than profit.
T H E B U S I N E S S O F F E A R Dr
Insurance companies, medical businesses, and other industries generate and spread unfounded fear to promote their products and services. This fear-mongering has led people to avoid naturally occurring products like ghee, coconut oil, and salt in favor of alternative products, fueling business growth. However, exploiting public fear for financial gain undermines well-being and leads to widespread dissatisfaction, illness, and societal decay. Cultivating spiritual wisdom in decision-making may be needed for individual and global welfare.
F R E E D O M D R
The document discusses whether an individual or organization that does not participate in a political freedom movement led by another group can be considered antinational. It provides several examples of individuals who may not have participated in political freedom struggles, including artists, scientists, government workers, and those focused on other social reforms. It argues that after 62 years of independence, it is important to move past judgments of others' viewpoints and actions during the freedom struggle, and instead focus on a shared vision of prosperity and equality for all.
H O L I S T I C M A N A G E M E N T O F G L O B A L R E C E S S I O N D R
1. The document discusses holistic management of global recession through spiritual practices like namasmarn, or remembering the name of God.
2. It recommends increasing productive activities like agriculture while reducing wasteful and unproductive activities that fuel economic booms and busts.
3. Regular practice of namasmarn by billions of people worldwide can help overcome sectarian biases and foster a global perspective needed to manage recessions holistically.
N E W E D I T I O N O F O U R T O U R D R
This document provides a summary of the author's tour of Southeast Asia, including stops in Hong Kong, Macau, Malaysia, and Singapore. Some key experiences mentioned include visiting attractions like Victoria Peak and Aberdeen Village in Hong Kong, temples and casinos in Macau, Genting Highlands in Malaysia, and sights around Singapore like the Merlion Park and Night Safari. The tour is described as providing beautiful scenery, cultural experiences, and opportunities for rest and relaxation between destinations.
C O M P L E M E N T A R I T Y & E Q U A L I T Y D R S H R I N I W A S K...
1) While equality has been an important ideal for governance, true governance of the universe is achieved through complementarity, not just equality.
2) Insisting only on superficial equality, like having similar food, clothes, and behaviors, stifles human growth and development. True equality allows for freedom and blossoming of each individual.
3) Namasmaran, or remembering the name of God, is a universal spiritual practice that helps reunify one's physiological self with their true self. It leads to the highest form of meditation and yoga by funneling all consciousness towards cosmic consciousness.
Y O G A T H E C O N N E C T I O N D R
Yoga is conceived in many ways and is a connection between one's global perspective, thoughts, emotions, and actions in every sphere of life. It also connects metabolic, endocrine, autonomic, and central nervous system activities as well as the right and left cerebral cortex. This yoga can be achieved through NAMASMARAN, as one can verify.
Y O G A K A R M A A N D N A M A S M A R A N D R
Nishkama karma, or action without attachment to results, is a concept in the Bhagavad Gita. While it seems impossible to act without thinking of results, subtle actions like thinking and feelings cannot be defined by their physical causes and effects. As actions evolve, they become less crude and more cosmic in nature, with results that cannot be quantified. The highest form of action is namasmāran, or remembering God, as it merges subjectivity and objectivity such that ownership of actions and results ceases. Namasmāran is widely practiced in religions and can help emancipate oneself and others.
Y O G A A N D S U P E R L I V I N G D R
The document discusses the principles of yoga. It states that there are three components to human response - cognition, affect, and conation. The final stage of yoga is the union of these three components, where one senses beyond normal capacity, feels on a deep emotional level, and responds in a way that transcends typical action. This culmination represents the accurate perception, personal satisfaction, and benevolence towards others that marks both individual and universal progress. Remembering God's name, as inspired by a guru, can help achieve this stage of yoga.
Y O G A A N D S U P E R J O Y D R
Yoga and superjoy can lead to a union at physical, emotional, intellectual, and spiritual levels that overcomes differences and disputes. The highest union is a spiritual one between a true guru and disciple through namasmarn, or remembrance of God. This spiritual union can dissolve contradictions like theism and atheism, and what the world needs is a realization that encompasses all differences.
Y O G A A N D S T R E S S Dr
Yoga integrates the right and left cerebral cortex, or right and left brain. The inability to see unity across different fields and paths is due to a deficiency in developing and integrating the right and left brain, leading to sectarianism and injustice. Even an intelligent person can be antisocial without balancing left brain development with the right brain through practices like namasmaran.
C H A N G I N G Y O U R S E L F O R W O R L D D R
This document discusses different perspectives on change and the world. Some see the world and past positively, others negatively. People respond to their own perceptions inevitably, leading to conflict. The practice of NAMASMARAN allows one to change themselves so they see the world more realistically and act less compulsively, finding mutual satisfaction instead of imposing views. This conscious evolution relieves the burden of needing to change oneself or the world.
World Famous Prayer Interpretation By Dr
[1] This prayer is meant to wish happiness, health, and well-being for all, with no grief.
[2] Some object to prayers, seeing them as weakness, but they can be a way to remove "blocks" like ego and gain strength from cosmic powers that we are extensions of.
[3] Prayers and chanting can effectively remove these blocks by connecting us to the source of empowerment and the universe, just as reconnecting leaves to the roots of a tree makes them stronger.
W H Y N A M A S M A R A N D R
Namasmran, or remembering God, is a simple practice that can have benevolent and emancipating effects on both individuals and the environment. While some theories blame issues like poverty, oppression, or biological drives for individual and social problems, these explanations are only partially accurate and can breed hatred. Alternatively, theories that blame individual frailty are also imperfect and can lead to self-abnegation. Namasmran is a process billions already engage in, without using this name, to blossom as individuals. If more undertook this practice of remembering their true self, positive change for all would be inevitable, though currently unproven.
W H Y P R A Y E R D R
1) Prayer is meant to catalyze the culmination of any work in complete satisfaction and global welfare.
2) The essence of worshipping Lord Ganesha is that he represents the experience of enlightenment and cosmic oneness with one's inner and outer environment.
3) It is customary to pray to Lord Ganesha before starting any work because realizing truth is necessary for accurate vision, decision making, and successful action. These prayers provide holistic health or self-realization.
W H Y H O L I S T I C M E D I C I N E D R S H R I N I W A S K A S H A L ...
The document discusses why holistic medicine is important. It notes that people have experienced the benefits of treatments like yoga, Ayurveda, and allopathy. More importantly, it is realized that different modalities of treatment, even those not considered formal treatments like music and clothing, work together in complementary and synergistic ways at different levels in the body. Since the most important purpose of medicine is to promote holistic health and eradicate disease and misery, the skills and wisdom from all fields worldwide should come together to achieve this goal.
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Holistic Education Dr
Holistic education aims to facilitate physical, emotional, intellectual, and spiritual growth to benefit individuals, groups, nations, and the world. It takes a holistic approach rather than focusing on petty pursuits or piecemeal development. A lack of holistic education has led to out-of-control industries that produce unnecessary products, consume resources, add to pollution, and promote an atmosphere conducive to terrorism. Namasmaran, or remembrance of God, is at the core of holistic education.
Stress and holistic health dr. shriniwas j. kashalikar
The document discusses holistic health and the need for holistic policies and approaches. It argues that the current education system fails to promote creativity and productivity. It also states that fulfilling all human needs in an appropriate way, such as through physical activity and social interaction, is essential for individual and social well-being. The document advocates for holistic medicine and non-restrictive laws to allow for holistic treatment. It suggests that regular remembrance of the divine (Namasmaran) can help enable holistic blossoming of individuals and society.
Stress and holistic_health_dr._shriniwas_j._kashalikar
The document discusses holistic health and the need for holistic policies and approaches. It argues that the current education system focuses too much on academics and not enough on creativity, productivity, and practical skills. This causes problems like unemployment, poverty, and lack of dignity in labor-oriented jobs. The document advocates for fulfilling all human needs - including physical, psychological, social, and intellectual - in a balanced way in order to achieve true well-being or "holistic health" for individuals and society. It also discusses the need for non-restrictive laws around holistic medical training and treatment approaches. NAMASMARAN, or remembering the divine name, is presented as a way to cultivate holistic perspectives and bloss
Holistic renaissance dr shriniwas kashalikar
The divisions such as spiritual, material, theist, atheist, superstitious, rationalist etc would begin to dissolve in common pursuit of HOLISTIC RENAISSANCE through the common minimum program of NAMASMARAN.
Holistic renaissance dr shriniwas kashalikar
HOLISTIC RENAISSANCE
HOLISTIC RENAISSANCE is the development of perspective, policies, plans, programs and implementation; of these for individual and global blossoming. The message of Geeta is; HOLISTIC RENAISSANCE is bound to manifest; through the life struggle (DHARMA YUDDHA) irrespective of whether we support it or oppose!
Health geeta and namasmaran dr shriniwas kashalikar
HEALTH GEETA AND NAMASMARAN
The divisions such as spiritual, material, theist, atheist, superstitious, rationalist etc would begin to dissolve in common pursuit of HOLISTIC RENAISSANCE through the common minimum program of NAMASMARAN.
T H E B U S I N E S S O F F E A R Dr
Insurance companies, medical businesses, and other industries generate and spread unfounded fear to promote their products and services. This fear-mongering has led people to avoid naturally occurring products like ghee, coconut oil, and salt in favor of alternative products, fueling business growth. However, exploiting public fear for financial gain undermines well-being and can have widespread health impacts. Spiritual practices like remembrance of God's name may help implement wiser policies focused on individual and global welfare rather than profit.
T H E B U S I N E S S O F F E A R Dr
Insurance companies, medical businesses, and other industries generate and spread unfounded fear to promote their products and services. This fear-mongering has led people to avoid naturally occurring products like ghee, coconut oil, and salt in favor of alternative products, fueling business growth. However, exploiting public fear for financial gain undermines well-being and leads to widespread dissatisfaction, illness, and societal decay. Cultivating spiritual wisdom in decision-making may be needed for individual and global welfare.
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Stress and holistic health dr. shriniwas j. kashalikar
Stress and holistic health dr. shriniwas j. kashalikar
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Health geeta and namasmaran dr shriniwas kashalikar
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More from Abhishek Yelgalwar
F R E E D O M D R
The document discusses whether an individual or organization that does not participate in a political freedom movement led by another group can be considered antinational. It provides several examples of individuals who may not have participated in political freedom struggles, including artists, scientists, government workers, and those focused on other social reforms. It argues that after 62 years of independence, it is important to move past judgments of others' viewpoints and actions during the freedom struggle, and instead focus on a shared vision of prosperity and equality for all.
H O L I S T I C M A N A G E M E N T O F G L O B A L R E C E S S I O N D R
1. The document discusses holistic management of global recession through spiritual practices like namasmarn, or remembering the name of God.
2. It recommends increasing productive activities like agriculture while reducing wasteful and unproductive activities that fuel economic booms and busts.
3. Regular practice of namasmarn by billions of people worldwide can help overcome sectarian biases and foster a global perspective needed to manage recessions holistically.
N E W E D I T I O N O F O U R T O U R D R
This document provides a summary of the author's tour of Southeast Asia, including stops in Hong Kong, Macau, Malaysia, and Singapore. Some key experiences mentioned include visiting attractions like Victoria Peak and Aberdeen Village in Hong Kong, temples and casinos in Macau, Genting Highlands in Malaysia, and sights around Singapore like the Merlion Park and Night Safari. The tour is described as providing beautiful scenery, cultural experiences, and opportunities for rest and relaxation between destinations.
C O M P L E M E N T A R I T Y & E Q U A L I T Y D R S H R I N I W A S K...
1) While equality has been an important ideal for governance, true governance of the universe is achieved through complementarity, not just equality.
2) Insisting only on superficial equality, like having similar food, clothes, and behaviors, stifles human growth and development. True equality allows for freedom and blossoming of each individual.
3) Namasmaran, or remembering the name of God, is a universal spiritual practice that helps reunify one's physiological self with their true self. It leads to the highest form of meditation and yoga by funneling all consciousness towards cosmic consciousness.
Y O G A T H E C O N N E C T I O N D R
Yoga is conceived in many ways and is a connection between one's global perspective, thoughts, emotions, and actions in every sphere of life. It also connects metabolic, endocrine, autonomic, and central nervous system activities as well as the right and left cerebral cortex. This yoga can be achieved through NAMASMARAN, as one can verify.
Y O G A K A R M A A N D N A M A S M A R A N D R
Nishkama karma, or action without attachment to results, is a concept in the Bhagavad Gita. While it seems impossible to act without thinking of results, subtle actions like thinking and feelings cannot be defined by their physical causes and effects. As actions evolve, they become less crude and more cosmic in nature, with results that cannot be quantified. The highest form of action is namasmāran, or remembering God, as it merges subjectivity and objectivity such that ownership of actions and results ceases. Namasmāran is widely practiced in religions and can help emancipate oneself and others.
Y O G A A N D S U P E R L I V I N G D R
The document discusses the principles of yoga. It states that there are three components to human response - cognition, affect, and conation. The final stage of yoga is the union of these three components, where one senses beyond normal capacity, feels on a deep emotional level, and responds in a way that transcends typical action. This culmination represents the accurate perception, personal satisfaction, and benevolence towards others that marks both individual and universal progress. Remembering God's name, as inspired by a guru, can help achieve this stage of yoga.
Y O G A A N D S U P E R J O Y D R
Yoga and superjoy can lead to a union at physical, emotional, intellectual, and spiritual levels that overcomes differences and disputes. The highest union is a spiritual one between a true guru and disciple through namasmarn, or remembrance of God. This spiritual union can dissolve contradictions like theism and atheism, and what the world needs is a realization that encompasses all differences.
Y O G A A N D S T R E S S Dr
Yoga integrates the right and left cerebral cortex, or right and left brain. The inability to see unity across different fields and paths is due to a deficiency in developing and integrating the right and left brain, leading to sectarianism and injustice. Even an intelligent person can be antisocial without balancing left brain development with the right brain through practices like namasmaran.
C H A N G I N G Y O U R S E L F O R W O R L D D R
This document discusses different perspectives on change and the world. Some see the world and past positively, others negatively. People respond to their own perceptions inevitably, leading to conflict. The practice of NAMASMARAN allows one to change themselves so they see the world more realistically and act less compulsively, finding mutual satisfaction instead of imposing views. This conscious evolution relieves the burden of needing to change oneself or the world.
World Famous Prayer Interpretation By Dr
[1] This prayer is meant to wish happiness, health, and well-being for all, with no grief.
[2] Some object to prayers, seeing them as weakness, but they can be a way to remove "blocks" like ego and gain strength from cosmic powers that we are extensions of.
[3] Prayers and chanting can effectively remove these blocks by connecting us to the source of empowerment and the universe, just as reconnecting leaves to the roots of a tree makes them stronger.
W H Y N A M A S M A R A N D R
Namasmran, or remembering God, is a simple practice that can have benevolent and emancipating effects on both individuals and the environment. While some theories blame issues like poverty, oppression, or biological drives for individual and social problems, these explanations are only partially accurate and can breed hatred. Alternatively, theories that blame individual frailty are also imperfect and can lead to self-abnegation. Namasmran is a process billions already engage in, without using this name, to blossom as individuals. If more undertook this practice of remembering their true self, positive change for all would be inevitable, though currently unproven.
W H Y P R A Y E R D R
1) Prayer is meant to catalyze the culmination of any work in complete satisfaction and global welfare.
2) The essence of worshipping Lord Ganesha is that he represents the experience of enlightenment and cosmic oneness with one's inner and outer environment.
3) It is customary to pray to Lord Ganesha before starting any work because realizing truth is necessary for accurate vision, decision making, and successful action. These prayers provide holistic health or self-realization.
W H Y H O L I S T I C M E D I C I N E D R S H R I N I W A S K A S H A L ...
The document discusses why holistic medicine is important. It notes that people have experienced the benefits of treatments like yoga, Ayurveda, and allopathy. More importantly, it is realized that different modalities of treatment, even those not considered formal treatments like music and clothing, work together in complementary and synergistic ways at different levels in the body. Since the most important purpose of medicine is to promote holistic health and eradicate disease and misery, the skills and wisdom from all fields worldwide should come together to achieve this goal.
W H E R E I S Z E R O D R
Zero is an important mathematical concept that gives meaning and structure but its existence is complex. Zero represents nothingness or absence, but nothingness cannot truly exist on its own - zero only has meaning in relation to other entities like time, space, and an observer. The concept of zero has paradoxically led to ideas of endings and death, though its origins and nature remain uncertain and indeterminate. This document aims to provoke thought about the nature and existence of zero.
W H A T I S W E L L B E I N G Dr
Physical health is indicated by attributes like strength, coordination, posture, and endurance. In aging populations, good memory, senses, sleep, mood, and skin are also indicators. However, the most important sign of wellbeing is being connected to one's true or cosmic self through a process called anusandhan. This state appears to have a benevolent, enlightening effect on the universe. Whether the practice of namasmaran can help achieve this mental state of objective wellbeing is for readers to experience.
P R A Y E R S O F W I S D O M D R
This document contains two Sanskrit prayers. The first prayer honors the goddess Sharada and describes her as enlightening, holding a veena (musical instrument) and book, sitting on a lotus, and destroying ignorance. The second prayer honors the cosmic principle of the guru, saying the guru embodies the qualities of Brahma, Vishnu, and Maheshvara and represents the three gunas or qualities of sattva, raja, and tama. It explains the guru takes followers beyond these three gunas from ignorance to knowledge.
P R A Y E R F O R 21 S T C E N T U R Y D R S H R I N I W A S K A S H A L...
This prayer asks God to remind the speaker of their connection to God and help them feel victorious over distractions. It also asks God to teach their mission for the universe and convince the speaker to spend their life serving that mission without faltering. Finally, the prayer requests that God remind the speaker of their duty to God every moment until their last breath and prevent any confusion, so they can accept and live in God's service with gratitude.
P R A L H A D S A I D D R
1. Pralhada argues that most saints and sages renounce the world and seek their own liberation, but he does not want to do this as he is the only savior for billions of people.
2. Stress is a universal phenomenon but is not well understood by all, and it is the duty of the fortunate few who understand stress to help others manage it.
3. In modern times, individual liberation and stress management are not possible and are intertwined with the liberation and stress management of billions of others.
P H Y S I O L O G Y O F N A M A S M A R A N D R
1) Meru refers to the brain or vertebral column, which supports consciousness and life.
2) Meru-mani refers to a large bead used in rosaries for counting repetitions of a mantra during namasmaran (remembrance of God's name).
3) It is recommended not to pass over the meru-mani bead when counting repetitions, in order to replicate the flow of impulses between the left and right hemispheres of the brain during meditation and prayer.
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There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
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