Donna Howard quit her job as a radiology director to open Holding Hands Resale Shop in Oxford, Mississippi to provide employment for people with mental illnesses like her daughter Cassie who has paranoid schizophrenia. The shop employs 8 people including Cassie and has been very successful due to generous donations from the local community who support its mission. It has provided Cassie with a kind work environment where she feels treated better than her previous job.