The document analyzes the profitability positions of selected private sector banks in India, focusing on profitability ratios such as interest spread, net profit margin, return on long-term loan, return on net worth, and adjusted cash margin over a 10-year period from 2002-2012. It highlights the significant impact of private sector banks on the banking landscape in India and their successful adaptation to technological advancements. The findings indicate no significant relationship between interest spread and net profit margin across the studied banks, while a significant relationship was found in return on long-term funds.