Fishbone Diagram Template
Name: Cause Effect
To complete click on grey box and type.
People
Environment
Methods
Equipment
Materials
How to develop your cause and effect diagram: 1. Identify practice problem you are trying to improve in the effect box. 2. In each category of causes, (a) people, (b) environment, (c) materials, (d) methods, and (e) equipment input causes for the effect. (See example and rubric).
8/19/2019 VERSION A
Template: Failure Modes and Effects Analysis
Step in Process
Failure
Mode
Failure Cause
Failure Effect
Occurrence Likelihood
Detection
Likelihood
Severity
Risk Profile Number
Actions to Mitigate Risk
Occurrence Likelihood rate 1-10 (10 means most likely to occur)
Detection Likelihood rate 1-10 (10 means least likely to be detected)
Severity rate 1-10 (10 means most likely to cause severe harm)
To calculate Risk Profile Number: Multiply Occurrence Likelihood times Detection Likelihood times Severity = Risk Profile Number
Submit completed FMEA form to assignment link for grading, place on presentation slide, and summarize FMEA findings in your presentation slide. (see Practice Problem Analysis Guidelines and Rubric)
9/12/2019 Version
8
Esophageal cancer and smoking
Name
Chamberlin University
PICOT Question
Are men 45 years of age and older (P) who have a one-year history of smoking or less (I) at an increased risk of developing esophageal cancer (O) compared with men age 45 and older (P) who have no smoking history (C)?
Evidence Synthesis of Literature to Address Practice Problem
According to the Cancer Research UK (2020), cancer of the esophagus is more common in older people. Around 40% of the members of the population develop esophageal cancer at the age of 75 and above. The Cancer Research UK (2020) equally notes that an estimated lifetime risk of being diagnosed with esophageal cancer us 2% for males and 1% for females in the United Kingdom. The findings of the Cancer Research UK (2020) indicate that 59% of esophageal cancer cases are preventable, but the condition is associated with a number of risk factors such as tobacco smoking, alcohol intake, and radiation exposure among other risk factors.
According to a cohort study conducted by Fan et al. (2008), tobacco smoking and alcohol consumption were established as the major risk factors for esophageal squamous cell carcinoma (ESCC), especially in the western population. The study reports many retrospective studies that have demonstrated a synergic effect of alcohol and smoking in ESCC risk. Nevertheless, prospective studies on esophageal cancer especially in high incidence regions are scare and their results have been inconsistent. Fan et al. (2008) equally reports ...
Number of Pages 4 (Double Spaced)Number of sources 8Writi.docxcherishwinsland
Number of Pages: 4 (Double Spaced)
Number of sources: 8
Writing Style: APA
Type of document: Coursework
Category: Healthcare
Order Instructions:
Comprehensive Article Review
Caverly, T.J., Fagerlin, A, & Wiener, R.S. (2018, January 22). Comparison of observed harms and expected mortality benefit for persons in the Veterans Health Affairs Lung Cancer Screening Demonstration Project. JAMA Internal Medicine.
1. What research questions are addressed in this study and what is their purpose (5 points)?
2. What type of research design was used (experimental, quasi-experimental, correlational) in this study and what led you to your decision (5 points)?
3. Are the instruments in this study valid and reliable, why or why not (10 points)?
4. Discuss the specific results of each of the ANCOVAs (analysis of covariance) done in this study. What was the purpose of"each" of the ANCOVAs? What was the covariate in each and why did they do an ANCOVA in each case (5 points)?
5. In the Tables, results are presented, Please explain the tables and summarize the results (15 points).
6. Explain, in simple language, any significant results of this study (25 points)?
7. Identify and discuss any threats to internal and/or external validity in this study (10 points).
8. If you could redesign this study correcting anything you have found wrong with the research, what would you correct and how would you do it (20 points)?
Opinion
EDITORIAL
Reducing Harms in Lung Cancer Screening
Bach to the Future
Michael ln cze, MD, MSEd: Rita F. Redberg, MD, MSc
TbeUS PreventativeServices Task Force cmrcntly recom mends si:;ree ning (grade Brecommendation)for lung canc er witha nnuallow-dose computed tomo graph}' for high-risk in dividuals ages55 to 80 years, defined as those having greate r
gLblefor LCS using the Bach risk tool,11 a vaJidatcd risk model usingsex,age, smokingduration, durationof abstinence from smoking and number of cigarettes smoked per day as inpu ts.
The asto undingly high ratesof false-pos itiveresults in the low
=Related attid e
than a 30 pack-year cumula tivesmoking historyand h av• ing quit with in the past 15 years.1 The evide nce to sup
est risk quintiles (eg, 2221false-positive resul ts per lung ca n cer death averted and a NNS of nearly 5600 in quintile1), as well as extremelylow ratesoflungcancerincidencein the low est-risk groups, confirm trends illustrated in previous stud
port thisrecommendation overwhelminglycomes rrom the Na
tional Lung CancerScreenfngTrial(NL ST). While3 other large randomized clinical trials failed to show any mortality ben efit tolung cancer screening (LCS), the NLST demonstrateda 20% reduction in lungcan ce r mortality,a lo ng with a 6.7% re duction in .ill-ca use mortality, when compared with an an nual chest radiograph, witb a number needed toscreen (NNS} of256to prevent I lung-cancerassociated death over3years.-2 5 Real-worldapplication ofLCS has been particularly .
This summary provides an overview of key information from the document:
1) The document reviews several epidemiological studies that examine the relationship between smokeless tobacco use and oral cancer risk. Case control and cohort studies from Sweden, India, and Norway generally found increased risks, though the magnitude of risk depended on the type of smokeless tobacco.
2) A review of 21 studies found that chewing tobacco and moist snuff carried low cancer risks under 2, while dry snuff was associated with higher relative risks from 4 to 13. However, studies may have overestimated risks by not adequately controlling for smoking and drinking.
3) Another review of 65 studies also noted small increased risks from case control studies, but cohort studies
Consumo de alcohol y riesgo de cáncer en un sitio específico un metanálisis i...Sonia Dorado Ayrampo
This document presents the results of a meta-analysis investigating the association between alcohol consumption and 23 different types of cancer. The analysis included 572 studies and over 486,000 cancer cases. The results show increased risks for several cancers with increasing alcohol intake, including oral cavity/pharynx, esophageal, colorectal, liver, laryngeal and female breast cancers. Heavy drinking was associated with the highest risks for these cancers. The analysis also found associations between alcohol and cancers of the stomach, gallbladder, pancreas, and lung.
Presentation by Preet K Dhillon during the panel on 'Health Effects of Exposure to Air Pollution, as part of the CPR Initiative on Climate, Energy and Environment Clearing the Air Seminar Series. This event was organised in partnership with the Public Health Foundation of India (PHFI)
1.
For this assignment,
I want you to create a single, APA 7-compliant, Word document. To earn full credit, you must do the following:
·
Page 1 = 20 pts: Proper APA 7 Title Page (watch the video and see p. 31 in the
Foundations text to help you create a perfect title page)
·
Page 2 = 60 pts (breakdown below): Simply answer the following questions
·
(1) What is your
approved research question from the Brainstorming Research Question HW assignment?
(5 pts)
·
(2) What is the title of the
research article you found?
(5 pts)
·
(3) Does the article contain the methodology the researchers used to conduct the study/research? To get full credit, you must
(a) name the methodology,
(b) cut and paste the paragraph from the article that details the methodology, AND
(c) highlight indicator words
.
(30 pts)
·
(4) Does the article contain findings or results of the research? To get full credit, you must
(a) cut and paste excerpts from the article that detail the findings (go to Discussion section or at times Conclusion), AND
(b) highlight specific words that detail the findings
.
(20 pts)
·
Page 3 = 20 pts: Create a proper APA 7 References Page with your ONE research article (refer to the video and see pp. 33-34 for the FORMAT you must use to create your reference and p. 32 for a perfect sample of what a References Page looks like.)
NOTES FOR TWO MORE RESEARCH ARTICLES 1
The Effects of Smoking on Lung Cancer Rates among Adults in New York
Pulla Rao Uppatala
MSc in Computer Science, King Graduate School
KG 604: Graduate Research & Critical Analysis
Dr. Aditi Puri
14 Nov 2022
New Research Article 1
Who: The assessment of cost-utility analysis of lung cancer screening and the paybacks on integrating smoking cessation interventions was performed by Villanti et al.
Why: This study aimed to assess whether LDCT screening for lung cancer among commercially insured individuals between 50 and 64 years at high risk for this disorder is turning out to be cost-effective. The authors also strived to quantify the extra payback of integrating smoking cessation solutions within lung cancer screening programs.
When: The authors analyzed their study in 2012 assuming that all existing smokers and half of the prior smoker population aged between 50 and 64 years were eligible for screening, with the minimum being set at least thirty packs –years of smoking.
Where: The researchers used dat.
This document is a student thesis analyzing the presence of Prevotella intermedia 17 within the human lung and its relationship to lung cancer and COPD. The initial analysis identified P. intermedia 17 in a metagenomic assembly of sputum samples from 30 patients. Further analysis using the P. intermedia 17 reference genome found it is present in lungs but reduced 85-99% in lung cancer and COPD patients compared to healthy controls. This discovery of P. intermedia 17 in lungs and its relationship to lung diseases could lead to a new diagnostic test, improving early detection and treatment outcomes. The thesis provides background on lung cancer, COPD, P. intermedia 17, and details the study methodology and results analyzing
Number of Pages 4 (Double Spaced)Number of sources 8Writi.docxcherishwinsland
Number of Pages: 4 (Double Spaced)
Number of sources: 8
Writing Style: APA
Type of document: Coursework
Category: Healthcare
Order Instructions:
Comprehensive Article Review
Caverly, T.J., Fagerlin, A, & Wiener, R.S. (2018, January 22). Comparison of observed harms and expected mortality benefit for persons in the Veterans Health Affairs Lung Cancer Screening Demonstration Project. JAMA Internal Medicine.
1. What research questions are addressed in this study and what is their purpose (5 points)?
2. What type of research design was used (experimental, quasi-experimental, correlational) in this study and what led you to your decision (5 points)?
3. Are the instruments in this study valid and reliable, why or why not (10 points)?
4. Discuss the specific results of each of the ANCOVAs (analysis of covariance) done in this study. What was the purpose of"each" of the ANCOVAs? What was the covariate in each and why did they do an ANCOVA in each case (5 points)?
5. In the Tables, results are presented, Please explain the tables and summarize the results (15 points).
6. Explain, in simple language, any significant results of this study (25 points)?
7. Identify and discuss any threats to internal and/or external validity in this study (10 points).
8. If you could redesign this study correcting anything you have found wrong with the research, what would you correct and how would you do it (20 points)?
Opinion
EDITORIAL
Reducing Harms in Lung Cancer Screening
Bach to the Future
Michael ln cze, MD, MSEd: Rita F. Redberg, MD, MSc
TbeUS PreventativeServices Task Force cmrcntly recom mends si:;ree ning (grade Brecommendation)for lung canc er witha nnuallow-dose computed tomo graph}' for high-risk in dividuals ages55 to 80 years, defined as those having greate r
gLblefor LCS using the Bach risk tool,11 a vaJidatcd risk model usingsex,age, smokingduration, durationof abstinence from smoking and number of cigarettes smoked per day as inpu ts.
The asto undingly high ratesof false-pos itiveresults in the low
=Related attid e
than a 30 pack-year cumula tivesmoking historyand h av• ing quit with in the past 15 years.1 The evide nce to sup
est risk quintiles (eg, 2221false-positive resul ts per lung ca n cer death averted and a NNS of nearly 5600 in quintile1), as well as extremelylow ratesoflungcancerincidencein the low est-risk groups, confirm trends illustrated in previous stud
port thisrecommendation overwhelminglycomes rrom the Na
tional Lung CancerScreenfngTrial(NL ST). While3 other large randomized clinical trials failed to show any mortality ben efit tolung cancer screening (LCS), the NLST demonstrateda 20% reduction in lungcan ce r mortality,a lo ng with a 6.7% re duction in .ill-ca use mortality, when compared with an an nual chest radiograph, witb a number needed toscreen (NNS} of256to prevent I lung-cancerassociated death over3years.-2 5 Real-worldapplication ofLCS has been particularly .
This summary provides an overview of key information from the document:
1) The document reviews several epidemiological studies that examine the relationship between smokeless tobacco use and oral cancer risk. Case control and cohort studies from Sweden, India, and Norway generally found increased risks, though the magnitude of risk depended on the type of smokeless tobacco.
2) A review of 21 studies found that chewing tobacco and moist snuff carried low cancer risks under 2, while dry snuff was associated with higher relative risks from 4 to 13. However, studies may have overestimated risks by not adequately controlling for smoking and drinking.
3) Another review of 65 studies also noted small increased risks from case control studies, but cohort studies
Consumo de alcohol y riesgo de cáncer en un sitio específico un metanálisis i...Sonia Dorado Ayrampo
This document presents the results of a meta-analysis investigating the association between alcohol consumption and 23 different types of cancer. The analysis included 572 studies and over 486,000 cancer cases. The results show increased risks for several cancers with increasing alcohol intake, including oral cavity/pharynx, esophageal, colorectal, liver, laryngeal and female breast cancers. Heavy drinking was associated with the highest risks for these cancers. The analysis also found associations between alcohol and cancers of the stomach, gallbladder, pancreas, and lung.
Presentation by Preet K Dhillon during the panel on 'Health Effects of Exposure to Air Pollution, as part of the CPR Initiative on Climate, Energy and Environment Clearing the Air Seminar Series. This event was organised in partnership with the Public Health Foundation of India (PHFI)
1.
For this assignment,
I want you to create a single, APA 7-compliant, Word document. To earn full credit, you must do the following:
·
Page 1 = 20 pts: Proper APA 7 Title Page (watch the video and see p. 31 in the
Foundations text to help you create a perfect title page)
·
Page 2 = 60 pts (breakdown below): Simply answer the following questions
·
(1) What is your
approved research question from the Brainstorming Research Question HW assignment?
(5 pts)
·
(2) What is the title of the
research article you found?
(5 pts)
·
(3) Does the article contain the methodology the researchers used to conduct the study/research? To get full credit, you must
(a) name the methodology,
(b) cut and paste the paragraph from the article that details the methodology, AND
(c) highlight indicator words
.
(30 pts)
·
(4) Does the article contain findings or results of the research? To get full credit, you must
(a) cut and paste excerpts from the article that detail the findings (go to Discussion section or at times Conclusion), AND
(b) highlight specific words that detail the findings
.
(20 pts)
·
Page 3 = 20 pts: Create a proper APA 7 References Page with your ONE research article (refer to the video and see pp. 33-34 for the FORMAT you must use to create your reference and p. 32 for a perfect sample of what a References Page looks like.)
NOTES FOR TWO MORE RESEARCH ARTICLES 1
The Effects of Smoking on Lung Cancer Rates among Adults in New York
Pulla Rao Uppatala
MSc in Computer Science, King Graduate School
KG 604: Graduate Research & Critical Analysis
Dr. Aditi Puri
14 Nov 2022
New Research Article 1
Who: The assessment of cost-utility analysis of lung cancer screening and the paybacks on integrating smoking cessation interventions was performed by Villanti et al.
Why: This study aimed to assess whether LDCT screening for lung cancer among commercially insured individuals between 50 and 64 years at high risk for this disorder is turning out to be cost-effective. The authors also strived to quantify the extra payback of integrating smoking cessation solutions within lung cancer screening programs.
When: The authors analyzed their study in 2012 assuming that all existing smokers and half of the prior smoker population aged between 50 and 64 years were eligible for screening, with the minimum being set at least thirty packs –years of smoking.
Where: The researchers used dat.
This document is a student thesis analyzing the presence of Prevotella intermedia 17 within the human lung and its relationship to lung cancer and COPD. The initial analysis identified P. intermedia 17 in a metagenomic assembly of sputum samples from 30 patients. Further analysis using the P. intermedia 17 reference genome found it is present in lungs but reduced 85-99% in lung cancer and COPD patients compared to healthy controls. This discovery of P. intermedia 17 in lungs and its relationship to lung diseases could lead to a new diagnostic test, improving early detection and treatment outcomes. The thesis provides background on lung cancer, COPD, P. intermedia 17, and details the study methodology and results analyzing
An Investigation of the Knowledge and Opinions of British Men Regarding Pros...Jedrik Martinez
The document is a dissertation that investigates the knowledge and opinions of British men regarding prostate cancer. It includes the following key points:
- The study surveyed 25 British men and found that most (76%) lacked knowledge about the causes of prostate cancer, though some knew family history and age were factors.
- Regarding screening and treatment, only 12% knew there is no screening program in the UK, while 68% did not know the treatment options.
- However, the men showed positive attitudes, as 80% were willing to undergo screening, 96% felt comfortable talking about prostate cancer, and most said they would not treat someone with prostate cancer differently.
The Case for Lung Cancer Screening ASRT presentationKimberly Luse
The document discusses the case for lung cancer screening through low-dose CT scans. It provides background on lung cancer statistics, risk factors, and previous research studies that have established the effectiveness of CT screening in reducing lung cancer mortality compared to chest X-rays. Major points covered include the National Lung Screening Trial findings of a 20% reduction in lung cancer deaths from low-dose CT screening, and the 2015 Centers for Medicare and Medicaid Services decision to cover low-dose CT screening for certain high-risk patients between the ages of 55-77 with a smoking history.
NOTES FOR TWO MORE RESEARCH ARTICLES1The Effe.docxkendalfarrier
NOTES FOR TWO MORE RESEARCH ARTICLES 1
The Effects of Smoking on Lung Cancer Rates among Adults in New York
Pulla Rao Uppatala
MSc in Computer Science, King Graduate School
KG 604: Graduate Research & Critical Analysis
Dr. Aditi Puri
14 Nov 2022
New Research Article 1
Who: The assessment of cost-utility analysis of lung cancer screening and the paybacks on integrating smoking cessation interventions was performed by Villanti et al.
Why: This study aimed to assess whether LDCT screening for lung cancer among commercially insured individuals between 50 and 64 years at high risk for this disorder is turning out to be cost-effective. The authors also strived to quantify the extra payback of integrating smoking cessation solutions within lung cancer screening programs.
When: The authors analyzed their study in 2012 assuming that all existing smokers and half of the prior smoker population aged between 50 and 64 years were eligible for screening, with the minimum being set at least thirty packs –years of smoking.
Where: The researchers used data from National Health Interview Survey on cigarette smoking conditions for individuals between 45 and 64 years who were making 30% of active smokers across the United States at the time. The cancer treatment costs were acquired from New York's taxpayer database, which provided information including physician, hospital, drug and ancillary costs eligible for insurer reimbursement.
How: The authors used qualitative research methods to build up on the prior simulation model to determine the utility cost of yearly, recurring LDCT screenings for the last 15 years within an assumed high-risk population of 18 million adults aged between 50 and 64 years. It specifically involved those who have consumed over 30 packs within their smoking history. The authors' findings indicate that the recurring yearly lung cancer screening within the high-risk population has been effective. Providing smoking cessation strategies within the yearly screening program has increased the cost-effectiveness of the disorder by between 40 and 45%.
New Research Article 2
Who: The study on Using a smoking cessation quitline to promote lung cancer screening was performed by Sharma et al.
Why: The goal of their study was to compare two alternatives to dispense information concerning lung cancer screening. This included a quitline, a mailed brochure pinned with in-depth messaging facilitated by a quitline coach. Therefore, the authors focused on assessing the strategy that will be effective and have a significant impact on the participants searching for information about lung cancer screening. The authors thus hypothesized that the individuals who received the brochure would repo.
2The Effects of Smoking on Lung Cancer R.docxrobert345678
2
The Effects of Smoking on Lung Cancer Rates among Adults in New York
Student Name
Course
Date
Article 1
Who: The assessment of cost-utility analysis of lung cancer screening and the paybacks on integrating smoking cessation interventions was performed by Villanti et al.
Why: This study aimed to assess whether LDCT screening for lung cancer among commercially insured individuals between 50 and 64 years at high risk for this disorder is turning out to be cost-effective. The authors also strived to quantify the extra payback of integrating smoking cessation solutions within lung cancer screening programs.
When: The authors analyzed their study in 2012 assuming that all existing smokers and half of the prior smoker population aged between 50 and 64 years were eligible for screening, with the minimum being set at least thirty packs –years of smoking.
Where: The researchers used data from National Health Interview Survey on cigarette smoking conditions for individuals between 45 and 64 years who were making 30% of active smokers across the United States at the time. The cancer treatment costs were acquired from New York's taxpayer database, which provided information including physician, hospital, drug and ancillary costs eligible for insurer reimbursement.
How: The authors used qualitative research methods to build up on the prior simulation model to determine the utility cost of yearly, recurring LDCT screenings for the last 15 years within an assumed high-risk population of 18 million adults aged between 50 and 64 years. It specifically involved those who have consumed over 30 packs within their smoking history. The authors' findings indicate that the recurring yearly lung cancer screening within the high-risk population has been effective. Providing smoking cessation strategies within the yearly screening program has increased the cost-effectiveness of the disorder by between 40 and 45%.
Article 2
Who: The study on Using a smoking cessation quitline to promote lung cancer screening was performed by Sharma et al.
Why: The goal of their study was to compare two alternatives to dispense information concerning lung cancer screening. This included a quitline, a mailed brochure pinned with in-depth messaging facilitated by a quitline coach. Therefore, the authors focused on assessing the strategy that will be effective and have a significant impact on the participants searching for information about lung cancer screening. The authors thus hypothesized that the individuals who received the brochure would report having spoken to their insurance company or physician and compare it to those who only received the brochure and made no contact.
When: The authors recruited their research participants in 2018
Where: The target population came from residents residing in New York State but outside Niagara and Erie counties.
How: The authors perfo.
This document contains summaries of 3 studies related to coffee consumption and health risks:
1) A 22-year longitudinal study found no association between caffeinated/decaffeinated coffee/tea intake and breast cancer risk, and higher caffeine intake may reduce postmenopausal breast cancer risk.
2) A 6-year study found an inverse association between hot tea and pharyngeal cancer, and direct association between coffee and gastric cancer. No associations were found for other cancers or drinks.
3) A meta-analysis of 13 studies found high coffee consumption may increase lung cancer risk, though residual smoking confounding requires cautious interpretation.
Association between variations in the fat mass and obesity-associated gene an...Enrique Moreno Gonzalez
It is clear that genetic variations in the fat mass and obesity-associated (FTO) gene affect body mass index and the risk of obesity. Given the mounting evidence showing a positive association between obesity and pancreatic cancer, this study aimed to investigate the relation between variants in the FTO gene, obesity and pancreatic cancer risk.
Primary Prevention Efforts to Reduce the Incidence of Breast and Upper Aerodi...Betty Kui
This document discusses a primary prevention strategy to reduce binge drinking and subsequent risks of breast and upper aerodigestive tract (UADT) cancers in New Jersey males and females aged 18-24. It finds this age group has the highest binge drinking rates and discusses how alcohol education programs in high schools and colleges could discourage binge drinking habits before they form and reduce cancer risks later in life. The strategy aims to lower incidence rates of these cancers, as over 25% of UADT cancers and 4% of breast cancers are attributed to alcohol consumption.
This document is a survey report on understanding of lung cancer among male and female students at Taylor's University. It includes an introduction to lung cancer, the objective of comparing understanding between genders, methodology of distributing surveys to 260 students, statistical analysis of the survey results, and conclusions. The analysis found that female respondents had a slightly better understanding of lung cancer than males, though overall understanding was low. Many were unaware that lung cancer can spread to other organs and that surgery is a primary treatment. The report provides statistics on lung cancer in Malaysia and factors that influence risk.
This document is a survey report on understanding of lung cancer among male and female students at Taylor's University. It includes an introduction to lung cancer, the objective to compare understanding between genders, methodology of distributing surveys to 260 students, statistical analysis of responses, and conclusions. The analysis found that female students had a slightly better understanding than males, though overall understanding was low. Many were unaware that lung cancer can affect other cancers and that surgery is a primary treatment. The report provides statistics on lung cancer in Malaysia and causes/risk factors.
From premalignant lesions to early gastric cancerLe Grand Métier
1. Gastric cancer remains a major cause of cancer incidence and mortality worldwide, though rates have declined in many countries. However, some populations have seen increasing or stable rates, particularly in younger age groups.
2. While overall rates are decreasing in most Western countries, some subgroups have shown rising corpus-dominant gastric cancer incidence, particularly younger white women. Similar trends have emerged in countries like South Korea and Brazil.
3. Possible reasons for these trends include changing gastric microecology with reduced H. pylori infection and increased autoimmune gastritis, particularly affecting the corpus region in younger cohorts. Continued monitoring is needed to understand these emerging patterns.
Women Smokers is More Risk from Colon Cancer - Springhill Medicalaleidadominik
It is now well-established that cancer is well-linked to smoking. And now according to researchers, cigarettes increase the odds for developing colon cancer, especially for women.
READ MORE:
http://linkd.in/11DqODo
http://bit.ly/16IGT3y
Bronchopulmonary cancers are common cancers with a poor prognosis. It is the leading cause of death by cancer in Algeria and in the world. Behind this unfavorable prognosis hides numerous disparities according to age, sex, and exposure to risk factors, ranking 4th among incident cancers and developing countries including Algeria, all sexes combined. It ranks 2nd cancers in men and 3rd among women. Whatever the age observed, the incidence of this cancer is higher in men than in women, however the gap is narrowing to the detriment of the latter. The results of scientific research agree to relate trends in incidence and mortality rates to tobacco consumption, including passive smoking. Furthermore, other risk factors are mentioned such as exposure to asbestos in the workplace or to radon for the general population, or even genetic predisposition. However, the weight of these etiological and/or predisposing factors is in no way comparable to that of tobacco in the genesis of lung cancer and the resulting mortality. We provide a literature review in our article on the descriptive and analytical epidemiology of lung cancer.
The document provides information about cancer prevention and screening. It discusses:
1. Overall prevention strategies like avoiding carcinogens and maintaining a healthy lifestyle to lower cancer risk.
2. Specific prevention strategies for common cancers like breast, prostate, lung and colorectal cancer.
3. Recommendations for cancer screening and websites with guidance on screening for early detection.
Evidence TableEvidence TablePICOT Question
[Insert here]APA Source Reference
(Include the DOI or URL. Use the source URL, not the library link.) Indicate: Peer Reviewed,
Clinical Guideline, or
Best Practice GuidelineAim, Hypothesis,
or Research QuestionConceptual or
Theoretical FrameworkResearch Design/MethodologyMeasurement
MethodSample Population
or SettingResearch Variables Data AnalysisFindingsGaps in ResearchSignificant Findings from a Critical Appraisal of the Evidence
(level, quality of the evidence)Good QuotesAdditional NotesEnd of Worksheet
Role of Clinical Trial Participation in Cancer Research: Barriers,
Evidence, and Strategies
Joseph M. Unger, Ph.D.1, Elise Cook, M.D.2, Eric Tai, M.D.3, and Archie Bleyer, M.D.4
1Fred Hutchinson Cancer Research Center, Seattle, Washington
2The University of Texas MD Anderson Cancer Center, Houston, Texas
3Centers for Disease Control and Prevention, Atlanta, Georgia
4St Charles Health System, Quality Department, Bend, Oregon
OVERVIEW
Fewer than 1 in 20 adult cancer patients enroll in cancer clinical trials. But although barriers to
trial participation have been the subject of frequent study, the rate of trial participation has not
changed substantially over time. Barriers to trial participation are structural, clinical, and
attitudinal, and differ according to demographic and socioeconomic factors. In this paper, we
characterize the nature of cancer clinical trial barriers, and we consider global and local strategies
for reducing barriers. We also consider the specific case of adolescents with cancer, and show that
the low rate of trial enrollment in this age group strongly correlates with limited improvements in
cancer population outcomes compared to other age groups. Our analysis suggests that a clinical
trial system that enrolls patients at higher rates produces treatment advances at a faster rate and
corresponding improvements in cancer population outcomes. Viewed in this light, the issue of
clinical trial enrollment is foundational, lying at the heart of the cancer clinical trial endeavor.
Fewer barriers to trial participation would allow trials to be completed more quickly and would
improve the generalizability of trial results. Moreover, increased accrual to trials is important to
patients, since trials provide patients the opportunity to receive the newest treatments. In an era of
increasing emphasis on a treatment decision-making process that incorporates the patient
perspective, the opportunity for patients to choose trial participation for their care is vital.
INTRODUCTION
The path from initial development of a new cancer drug to diffusion of the new therapy into
the cancer treatment community relies, crucially, on clinical trials, which represent the final
step in evaluating the efficacy of new therapeutic approaches for malignancy. It has been
repeatedly estimated that <5% of adult cancer patients enroll in cancer clinical trials.1,2
...
10 STRATEGIC POINTS 2
Ten Strategic Points
Grand Canyon University
DNP-815- O502: Scientific Underpinnings
10 Strategic Points Table
(Use this table to complete the 10 Strategic Points document for your project.)
10 Strategic Points
Comments/Feedback
Broad Topic Area
Impact of Medication Administration Errors on 3-4-Year-old Leukemia Patients
Literature Review
A. Verghese, A., Charlton, B., Kassirer, J. P., Ramsey, M., & Ioannidis, J. P. (2015). Inadequacies of physical examination as a cause of medical errors and adverse events: a collection of vignettes. The American journal of medicine, 128(12), 1322-1324.
The article looks at the “Inadequacies of physical examination as a cause of medical errors and adverse events: a collection of vignettes” from the American journal of medicine. It takes into consideration the fact that, the oversights in the corporeal assessment are a medical fault which aren’t studied via chart evaluation. Furthermore, the article states that these oversights in the corporeal assessments may be the primary contributors to the neglected or late diagnosis besides unnecessary exposure to contrast as well as radiation on the Leukemia patients. Either the authors indicate that the incorrect treatments resulting from these delays leads to unfavorable results like fainting on the Leukemia patient, lack of appetite on the side of the patient, worsening the Leukemia conditions which eventually can lead to early death of the patient.
B. Hockings, J. K., Owolabi, D. K., Broyles, J. E., & Wheelis, S. C. (2017). Impact of medication administration error on over 3 years Leukemia patients and the stimulating factors in acute leukemia and stem cell transplant patients. Supportive Care in Cancer, 25(6), 1853-1858.
The authors of this article explored the “Impact of medication administration error on over 3 years Leukemia patients and the stimulating factors in acute leukemia and stem cell transplant patients.” This article is from supportive care in cancer and it was retrieved from Google Scholar. The article authors acknowledge the fact that, the medication administration errors lead to severe impacts on the health conditions of the patient more especially the ones who are 3 – 4 years of Leukemia. According to the authors, the impacts associated with the medication administration errors may lead to worsening of the health condition of the patient, the rate of Leukemia advancement into higher stages may also increase with treatment or managing of this deadly disease being more complicated. The authors argue that using erroneous medicines, the Leukemia advancement increases without the knowledge of the patient which makes even the survival chances of the patient to reduce due to stress upon realizing that there was an error in his or her medication.
C. Douer, D. (2016). Efficacy and safety of vincristine sulfate liposome injection in the treatment of adult acute lymphocytic leukemia. The oncologist, 21(7), 840-847.
...
This study compared alcohol consumption between mothers with and without a family history of breast cancer. Data on alcohol intake was collected through questionnaires in the LEGACY Girls Study. Mothers with a family history of breast cancer reported higher average alcohol consumption (12.3 drinks/month) than mothers without a family history (10.1 drinks/month). This refuted the hypothesis that mothers with a family history would drink less due to alcohol's association with breast cancer risk. The results suggest mothers at higher breast cancer risk may not be sufficiently lowering other modifiable risk factors like alcohol intake. Future research should examine if family history influences other risk factors and the impact of specific alcohol types on breast cancer gene mutations.
What is the current evidence between alcohol and cancer?
Presentation given by Giota Mitrou PhD MSc, Head of Research Funding and Science Activities, World Cancer Research Fund International (WCRF International).
The document summarizes research on cancer, stress, and personality. It finds that while stress may accelerate tumor growth in animal models, studies do not show stress causes cancer in humans. Childhood adversity is linked to increased risk behaviors but its relationship to cancer is unclear. Personality does not determine cancer risk but may impact progression. Psychotherapy improves mood in cancer patients but does not extend survival. It can reduce chemotherapy side effects through classical conditioning approaches.
State of the Evidence - The Connection between Breast Cancer & the Environment v2zq
State of the Evidence - The Connection between Breast Cancer & the Environment - Resources for Healthy Children www.scribd.com/doc/254613619 - For more information, Please see Organic Edible Schoolyards & Gardening with Children www.scribd.com/doc/254613963 - Gardening with Volcanic Rock Dust www.scribd.com/doc/254613846 - Double Food Production from your School Garden with Organic Tech www.scribd.com/doc/254613765 - Free School Gardening Art Posters www.scribd.com/doc/254613694 - Increase Food Production with Companion Planting in your School Garden www.scribd.com/doc/254609890 - Healthy Foods Dramatically Improves Student Academic Success www.scribd.com/doc/254613619 - City Chickens for your Organic School Garden www.scribd.com/doc/254613553 - Huerto Ecológico, Tecnologías Sostenibles, Agricultura Organica www.scribd.com/doc/254613494 - Simple Square Foot Gardening for Schools - Teacher Guide www.scribd.com/doc/254613410 - Free Organic Gardening Publications www.scribd.com/doc/254609890 ~ breastcancerfund.org
You are assisting Dr. Jones with a procedure that has been classifie.docxShainaBoling829
You are assisting Dr. Jones with a procedure that has been classified as sterile. However, you later learn the patient acquired an iatrogenic infection. Who is ultimately responsible for this event? How would you determine responsibility? What information would be required to make this determination? Please support your answer with at least one reference.
Why is it important to know what type of infection a patient has? An infection is an infection, is an infection. Does it matter where it comes from, why or why not, please explain?
.
You are an intelligence analyst for the Federal Bureau of Investigat.docxShainaBoling829
You are an intelligence analyst for the FBI's Counterintelligence Division tasked with researching and producing a case study on a major espionage case from the past to help identify anomalies that could indicate future espionage. You have been assigned to write a 750-word case study on Robert Hanssen, Aldrich Ames, Ana Montes, or John Walker and address who was involved, when and where the espionage took place, what information was compromised, how it was obtained and shared, why the spy acted, lessons learned, and the case's impact.
An Investigation of the Knowledge and Opinions of British Men Regarding Pros...Jedrik Martinez
The document is a dissertation that investigates the knowledge and opinions of British men regarding prostate cancer. It includes the following key points:
- The study surveyed 25 British men and found that most (76%) lacked knowledge about the causes of prostate cancer, though some knew family history and age were factors.
- Regarding screening and treatment, only 12% knew there is no screening program in the UK, while 68% did not know the treatment options.
- However, the men showed positive attitudes, as 80% were willing to undergo screening, 96% felt comfortable talking about prostate cancer, and most said they would not treat someone with prostate cancer differently.
The Case for Lung Cancer Screening ASRT presentationKimberly Luse
The document discusses the case for lung cancer screening through low-dose CT scans. It provides background on lung cancer statistics, risk factors, and previous research studies that have established the effectiveness of CT screening in reducing lung cancer mortality compared to chest X-rays. Major points covered include the National Lung Screening Trial findings of a 20% reduction in lung cancer deaths from low-dose CT screening, and the 2015 Centers for Medicare and Medicaid Services decision to cover low-dose CT screening for certain high-risk patients between the ages of 55-77 with a smoking history.
NOTES FOR TWO MORE RESEARCH ARTICLES1The Effe.docxkendalfarrier
NOTES FOR TWO MORE RESEARCH ARTICLES 1
The Effects of Smoking on Lung Cancer Rates among Adults in New York
Pulla Rao Uppatala
MSc in Computer Science, King Graduate School
KG 604: Graduate Research & Critical Analysis
Dr. Aditi Puri
14 Nov 2022
New Research Article 1
Who: The assessment of cost-utility analysis of lung cancer screening and the paybacks on integrating smoking cessation interventions was performed by Villanti et al.
Why: This study aimed to assess whether LDCT screening for lung cancer among commercially insured individuals between 50 and 64 years at high risk for this disorder is turning out to be cost-effective. The authors also strived to quantify the extra payback of integrating smoking cessation solutions within lung cancer screening programs.
When: The authors analyzed their study in 2012 assuming that all existing smokers and half of the prior smoker population aged between 50 and 64 years were eligible for screening, with the minimum being set at least thirty packs –years of smoking.
Where: The researchers used data from National Health Interview Survey on cigarette smoking conditions for individuals between 45 and 64 years who were making 30% of active smokers across the United States at the time. The cancer treatment costs were acquired from New York's taxpayer database, which provided information including physician, hospital, drug and ancillary costs eligible for insurer reimbursement.
How: The authors used qualitative research methods to build up on the prior simulation model to determine the utility cost of yearly, recurring LDCT screenings for the last 15 years within an assumed high-risk population of 18 million adults aged between 50 and 64 years. It specifically involved those who have consumed over 30 packs within their smoking history. The authors' findings indicate that the recurring yearly lung cancer screening within the high-risk population has been effective. Providing smoking cessation strategies within the yearly screening program has increased the cost-effectiveness of the disorder by between 40 and 45%.
New Research Article 2
Who: The study on Using a smoking cessation quitline to promote lung cancer screening was performed by Sharma et al.
Why: The goal of their study was to compare two alternatives to dispense information concerning lung cancer screening. This included a quitline, a mailed brochure pinned with in-depth messaging facilitated by a quitline coach. Therefore, the authors focused on assessing the strategy that will be effective and have a significant impact on the participants searching for information about lung cancer screening. The authors thus hypothesized that the individuals who received the brochure would repo.
2The Effects of Smoking on Lung Cancer R.docxrobert345678
2
The Effects of Smoking on Lung Cancer Rates among Adults in New York
Student Name
Course
Date
Article 1
Who: The assessment of cost-utility analysis of lung cancer screening and the paybacks on integrating smoking cessation interventions was performed by Villanti et al.
Why: This study aimed to assess whether LDCT screening for lung cancer among commercially insured individuals between 50 and 64 years at high risk for this disorder is turning out to be cost-effective. The authors also strived to quantify the extra payback of integrating smoking cessation solutions within lung cancer screening programs.
When: The authors analyzed their study in 2012 assuming that all existing smokers and half of the prior smoker population aged between 50 and 64 years were eligible for screening, with the minimum being set at least thirty packs –years of smoking.
Where: The researchers used data from National Health Interview Survey on cigarette smoking conditions for individuals between 45 and 64 years who were making 30% of active smokers across the United States at the time. The cancer treatment costs were acquired from New York's taxpayer database, which provided information including physician, hospital, drug and ancillary costs eligible for insurer reimbursement.
How: The authors used qualitative research methods to build up on the prior simulation model to determine the utility cost of yearly, recurring LDCT screenings for the last 15 years within an assumed high-risk population of 18 million adults aged between 50 and 64 years. It specifically involved those who have consumed over 30 packs within their smoking history. The authors' findings indicate that the recurring yearly lung cancer screening within the high-risk population has been effective. Providing smoking cessation strategies within the yearly screening program has increased the cost-effectiveness of the disorder by between 40 and 45%.
Article 2
Who: The study on Using a smoking cessation quitline to promote lung cancer screening was performed by Sharma et al.
Why: The goal of their study was to compare two alternatives to dispense information concerning lung cancer screening. This included a quitline, a mailed brochure pinned with in-depth messaging facilitated by a quitline coach. Therefore, the authors focused on assessing the strategy that will be effective and have a significant impact on the participants searching for information about lung cancer screening. The authors thus hypothesized that the individuals who received the brochure would report having spoken to their insurance company or physician and compare it to those who only received the brochure and made no contact.
When: The authors recruited their research participants in 2018
Where: The target population came from residents residing in New York State but outside Niagara and Erie counties.
How: The authors perfo.
This document contains summaries of 3 studies related to coffee consumption and health risks:
1) A 22-year longitudinal study found no association between caffeinated/decaffeinated coffee/tea intake and breast cancer risk, and higher caffeine intake may reduce postmenopausal breast cancer risk.
2) A 6-year study found an inverse association between hot tea and pharyngeal cancer, and direct association between coffee and gastric cancer. No associations were found for other cancers or drinks.
3) A meta-analysis of 13 studies found high coffee consumption may increase lung cancer risk, though residual smoking confounding requires cautious interpretation.
Association between variations in the fat mass and obesity-associated gene an...Enrique Moreno Gonzalez
It is clear that genetic variations in the fat mass and obesity-associated (FTO) gene affect body mass index and the risk of obesity. Given the mounting evidence showing a positive association between obesity and pancreatic cancer, this study aimed to investigate the relation between variants in the FTO gene, obesity and pancreatic cancer risk.
Primary Prevention Efforts to Reduce the Incidence of Breast and Upper Aerodi...Betty Kui
This document discusses a primary prevention strategy to reduce binge drinking and subsequent risks of breast and upper aerodigestive tract (UADT) cancers in New Jersey males and females aged 18-24. It finds this age group has the highest binge drinking rates and discusses how alcohol education programs in high schools and colleges could discourage binge drinking habits before they form and reduce cancer risks later in life. The strategy aims to lower incidence rates of these cancers, as over 25% of UADT cancers and 4% of breast cancers are attributed to alcohol consumption.
This document is a survey report on understanding of lung cancer among male and female students at Taylor's University. It includes an introduction to lung cancer, the objective of comparing understanding between genders, methodology of distributing surveys to 260 students, statistical analysis of the survey results, and conclusions. The analysis found that female respondents had a slightly better understanding of lung cancer than males, though overall understanding was low. Many were unaware that lung cancer can spread to other organs and that surgery is a primary treatment. The report provides statistics on lung cancer in Malaysia and factors that influence risk.
This document is a survey report on understanding of lung cancer among male and female students at Taylor's University. It includes an introduction to lung cancer, the objective to compare understanding between genders, methodology of distributing surveys to 260 students, statistical analysis of responses, and conclusions. The analysis found that female students had a slightly better understanding than males, though overall understanding was low. Many were unaware that lung cancer can affect other cancers and that surgery is a primary treatment. The report provides statistics on lung cancer in Malaysia and causes/risk factors.
From premalignant lesions to early gastric cancerLe Grand Métier
1. Gastric cancer remains a major cause of cancer incidence and mortality worldwide, though rates have declined in many countries. However, some populations have seen increasing or stable rates, particularly in younger age groups.
2. While overall rates are decreasing in most Western countries, some subgroups have shown rising corpus-dominant gastric cancer incidence, particularly younger white women. Similar trends have emerged in countries like South Korea and Brazil.
3. Possible reasons for these trends include changing gastric microecology with reduced H. pylori infection and increased autoimmune gastritis, particularly affecting the corpus region in younger cohorts. Continued monitoring is needed to understand these emerging patterns.
Women Smokers is More Risk from Colon Cancer - Springhill Medicalaleidadominik
It is now well-established that cancer is well-linked to smoking. And now according to researchers, cigarettes increase the odds for developing colon cancer, especially for women.
READ MORE:
http://linkd.in/11DqODo
http://bit.ly/16IGT3y
Bronchopulmonary cancers are common cancers with a poor prognosis. It is the leading cause of death by cancer in Algeria and in the world. Behind this unfavorable prognosis hides numerous disparities according to age, sex, and exposure to risk factors, ranking 4th among incident cancers and developing countries including Algeria, all sexes combined. It ranks 2nd cancers in men and 3rd among women. Whatever the age observed, the incidence of this cancer is higher in men than in women, however the gap is narrowing to the detriment of the latter. The results of scientific research agree to relate trends in incidence and mortality rates to tobacco consumption, including passive smoking. Furthermore, other risk factors are mentioned such as exposure to asbestos in the workplace or to radon for the general population, or even genetic predisposition. However, the weight of these etiological and/or predisposing factors is in no way comparable to that of tobacco in the genesis of lung cancer and the resulting mortality. We provide a literature review in our article on the descriptive and analytical epidemiology of lung cancer.
The document provides information about cancer prevention and screening. It discusses:
1. Overall prevention strategies like avoiding carcinogens and maintaining a healthy lifestyle to lower cancer risk.
2. Specific prevention strategies for common cancers like breast, prostate, lung and colorectal cancer.
3. Recommendations for cancer screening and websites with guidance on screening for early detection.
Evidence TableEvidence TablePICOT Question
[Insert here]APA Source Reference
(Include the DOI or URL. Use the source URL, not the library link.) Indicate: Peer Reviewed,
Clinical Guideline, or
Best Practice GuidelineAim, Hypothesis,
or Research QuestionConceptual or
Theoretical FrameworkResearch Design/MethodologyMeasurement
MethodSample Population
or SettingResearch Variables Data AnalysisFindingsGaps in ResearchSignificant Findings from a Critical Appraisal of the Evidence
(level, quality of the evidence)Good QuotesAdditional NotesEnd of Worksheet
Role of Clinical Trial Participation in Cancer Research: Barriers,
Evidence, and Strategies
Joseph M. Unger, Ph.D.1, Elise Cook, M.D.2, Eric Tai, M.D.3, and Archie Bleyer, M.D.4
1Fred Hutchinson Cancer Research Center, Seattle, Washington
2The University of Texas MD Anderson Cancer Center, Houston, Texas
3Centers for Disease Control and Prevention, Atlanta, Georgia
4St Charles Health System, Quality Department, Bend, Oregon
OVERVIEW
Fewer than 1 in 20 adult cancer patients enroll in cancer clinical trials. But although barriers to
trial participation have been the subject of frequent study, the rate of trial participation has not
changed substantially over time. Barriers to trial participation are structural, clinical, and
attitudinal, and differ according to demographic and socioeconomic factors. In this paper, we
characterize the nature of cancer clinical trial barriers, and we consider global and local strategies
for reducing barriers. We also consider the specific case of adolescents with cancer, and show that
the low rate of trial enrollment in this age group strongly correlates with limited improvements in
cancer population outcomes compared to other age groups. Our analysis suggests that a clinical
trial system that enrolls patients at higher rates produces treatment advances at a faster rate and
corresponding improvements in cancer population outcomes. Viewed in this light, the issue of
clinical trial enrollment is foundational, lying at the heart of the cancer clinical trial endeavor.
Fewer barriers to trial participation would allow trials to be completed more quickly and would
improve the generalizability of trial results. Moreover, increased accrual to trials is important to
patients, since trials provide patients the opportunity to receive the newest treatments. In an era of
increasing emphasis on a treatment decision-making process that incorporates the patient
perspective, the opportunity for patients to choose trial participation for their care is vital.
INTRODUCTION
The path from initial development of a new cancer drug to diffusion of the new therapy into
the cancer treatment community relies, crucially, on clinical trials, which represent the final
step in evaluating the efficacy of new therapeutic approaches for malignancy. It has been
repeatedly estimated that <5% of adult cancer patients enroll in cancer clinical trials.1,2
...
10 STRATEGIC POINTS 2
Ten Strategic Points
Grand Canyon University
DNP-815- O502: Scientific Underpinnings
10 Strategic Points Table
(Use this table to complete the 10 Strategic Points document for your project.)
10 Strategic Points
Comments/Feedback
Broad Topic Area
Impact of Medication Administration Errors on 3-4-Year-old Leukemia Patients
Literature Review
A. Verghese, A., Charlton, B., Kassirer, J. P., Ramsey, M., & Ioannidis, J. P. (2015). Inadequacies of physical examination as a cause of medical errors and adverse events: a collection of vignettes. The American journal of medicine, 128(12), 1322-1324.
The article looks at the “Inadequacies of physical examination as a cause of medical errors and adverse events: a collection of vignettes” from the American journal of medicine. It takes into consideration the fact that, the oversights in the corporeal assessment are a medical fault which aren’t studied via chart evaluation. Furthermore, the article states that these oversights in the corporeal assessments may be the primary contributors to the neglected or late diagnosis besides unnecessary exposure to contrast as well as radiation on the Leukemia patients. Either the authors indicate that the incorrect treatments resulting from these delays leads to unfavorable results like fainting on the Leukemia patient, lack of appetite on the side of the patient, worsening the Leukemia conditions which eventually can lead to early death of the patient.
B. Hockings, J. K., Owolabi, D. K., Broyles, J. E., & Wheelis, S. C. (2017). Impact of medication administration error on over 3 years Leukemia patients and the stimulating factors in acute leukemia and stem cell transplant patients. Supportive Care in Cancer, 25(6), 1853-1858.
The authors of this article explored the “Impact of medication administration error on over 3 years Leukemia patients and the stimulating factors in acute leukemia and stem cell transplant patients.” This article is from supportive care in cancer and it was retrieved from Google Scholar. The article authors acknowledge the fact that, the medication administration errors lead to severe impacts on the health conditions of the patient more especially the ones who are 3 – 4 years of Leukemia. According to the authors, the impacts associated with the medication administration errors may lead to worsening of the health condition of the patient, the rate of Leukemia advancement into higher stages may also increase with treatment or managing of this deadly disease being more complicated. The authors argue that using erroneous medicines, the Leukemia advancement increases without the knowledge of the patient which makes even the survival chances of the patient to reduce due to stress upon realizing that there was an error in his or her medication.
C. Douer, D. (2016). Efficacy and safety of vincristine sulfate liposome injection in the treatment of adult acute lymphocytic leukemia. The oncologist, 21(7), 840-847.
...
This study compared alcohol consumption between mothers with and without a family history of breast cancer. Data on alcohol intake was collected through questionnaires in the LEGACY Girls Study. Mothers with a family history of breast cancer reported higher average alcohol consumption (12.3 drinks/month) than mothers without a family history (10.1 drinks/month). This refuted the hypothesis that mothers with a family history would drink less due to alcohol's association with breast cancer risk. The results suggest mothers at higher breast cancer risk may not be sufficiently lowering other modifiable risk factors like alcohol intake. Future research should examine if family history influences other risk factors and the impact of specific alcohol types on breast cancer gene mutations.
What is the current evidence between alcohol and cancer?
Presentation given by Giota Mitrou PhD MSc, Head of Research Funding and Science Activities, World Cancer Research Fund International (WCRF International).
The document summarizes research on cancer, stress, and personality. It finds that while stress may accelerate tumor growth in animal models, studies do not show stress causes cancer in humans. Childhood adversity is linked to increased risk behaviors but its relationship to cancer is unclear. Personality does not determine cancer risk but may impact progression. Psychotherapy improves mood in cancer patients but does not extend survival. It can reduce chemotherapy side effects through classical conditioning approaches.
State of the Evidence - The Connection between Breast Cancer & the Environment v2zq
State of the Evidence - The Connection between Breast Cancer & the Environment - Resources for Healthy Children www.scribd.com/doc/254613619 - For more information, Please see Organic Edible Schoolyards & Gardening with Children www.scribd.com/doc/254613963 - Gardening with Volcanic Rock Dust www.scribd.com/doc/254613846 - Double Food Production from your School Garden with Organic Tech www.scribd.com/doc/254613765 - Free School Gardening Art Posters www.scribd.com/doc/254613694 - Increase Food Production with Companion Planting in your School Garden www.scribd.com/doc/254609890 - Healthy Foods Dramatically Improves Student Academic Success www.scribd.com/doc/254613619 - City Chickens for your Organic School Garden www.scribd.com/doc/254613553 - Huerto Ecológico, Tecnologías Sostenibles, Agricultura Organica www.scribd.com/doc/254613494 - Simple Square Foot Gardening for Schools - Teacher Guide www.scribd.com/doc/254613410 - Free Organic Gardening Publications www.scribd.com/doc/254609890 ~ breastcancerfund.org
You are assisting Dr. Jones with a procedure that has been classifie.docxShainaBoling829
You are assisting Dr. Jones with a procedure that has been classified as sterile. However, you later learn the patient acquired an iatrogenic infection. Who is ultimately responsible for this event? How would you determine responsibility? What information would be required to make this determination? Please support your answer with at least one reference.
Why is it important to know what type of infection a patient has? An infection is an infection, is an infection. Does it matter where it comes from, why or why not, please explain?
.
You are an intelligence analyst for the Federal Bureau of Investigat.docxShainaBoling829
You are an intelligence analyst for the FBI's Counterintelligence Division tasked with researching and producing a case study on a major espionage case from the past to help identify anomalies that could indicate future espionage. You have been assigned to write a 750-word case study on Robert Hanssen, Aldrich Ames, Ana Montes, or John Walker and address who was involved, when and where the espionage took place, what information was compromised, how it was obtained and shared, why the spy acted, lessons learned, and the case's impact.
You are a Wichita Police Department detective working in the major c.docxShainaBoling829
You are a Wichita Police Department detective working in the major crimes unit, and you are assigned to a joint federal–state–city crime task force working on a number of major drug cases. Over a period of several months, your task force has been able to gather information and make cases on several of the drug suppliers, drug dealers, and drug buyers in the Wichita metropolitan area. The task force is about to complete its mission by filing criminal charges in the federal district court, the state district court, or the Wichita Municipal Court against these various suspects. These suspects will not be arrested until the warrants are issued.
Your job is to make recommendations concerning which jurisdictions should file the charges on which defendants. You will need to evaluate the criminal statutes and penalties in each jurisdiction and even the rules of evidence to determine where your task force has the best chance of obtaining a conviction and in getting the punishment to fit the crime.
The memo that you receive from your Drug Enforcement Administration (DEA) task force supervisor explains the situation:
MEMO
Re: Charging Decisions
You are the primary investigator in the cases against Jones, Smith, and Thompson. As I review your reports, it appears that each of these cases has strengths and weaknesses that we should evaluate before we determine whether to file charges in the U.S. District Court, the Sedgwick County District Court for the State of Kansas, or the Wichita Municipal Court. I will summarize those strengths and weaknesses here to make sure I am reading your reports correctly. I need you to give me advice on where you think these charges should be brought.
Jones has been working for you as a confidential informant because you have evidence against him for a February 6, 2005 third possession of cocaine after convictions in 1993 and 1994. He appears to have followed the terms of his deal with you to introduce our undercover agents to his dealer. We have promised not to prosecute for any drug offenses he may commit in the presence of our undercover agent while playing the role of our informant. His assistance has enabled us to get sufficient evidence on Smith and Thompson to obtain convictions. Based on Jones’ two prior convictions for possession of cocaine, we would normally want him to go to federal court, where the maximum sentences are available. However, because of his cooperation, we could file the case in the Sedgwick County, Kansas, and district court under state law. We could even change the charge to a drug paraphernalia offense and send his case to the city of Wichita.
How do you think we should proceed concerning Jones' February 6, 2005 cocaine possession? (30%)
He will probably plead guilty unless we send him to federal court. Where do you want to file the case? (20%)
Smith has sold cocaine to our undercover agents on two occasions: July 12, 2005 and August 3, 2005. We have found no prior record on this individual, bu.
You are a primary care physician in a large group practice that uses.docxShainaBoling829
You are a primary care physician in a large group practice that uses an electronic health record (EHR). At the beginning of each visit, you view a dashboard of preventive care measures - like flu vaccine, colon cancer screening, cholesterol tests - that are due for your patient, based on age, medical history (problem list), and medication list stored in the EHR
.
You are a police officer assigned to a task force that is investigat.docxShainaBoling829
You are a police officer assigned to a task force that is investigating major drug trafficking operations in your jurisdiction. As part of the investigative process, a judge has issued a wiretap order for a suspect’s phone. You are assigned the responsibility of monitoring phone conversations, and you overhear the suspect as well as other individuals who may or may not be involved in the drug ring. Before obtaining enough evidence to arrest and prosecute the suspect, you hear evidence related to other types of criminal activity.
Assignment Guidelines
Address the following in 900–1,200 words:
What constitutional issues are involved in the scenario that dictates what you can and cannot do related to the evidence of other criminal activity outside the scope of the original wiretap order? Explain.
If you arrest the other individuals for the crimes not associated with the reasons for the wiretap, what happens to any future evidence that might be obtained from the wiretap? Why?
If you fail to arrest the other individuals, are there any potential risks involved? Explain you answer.
Be sure to reference all sources using APA style.
.
You are a patient at seeing a Plastic Surgeon for a consultation. Du.docxShainaBoling829
You are a patient at seeing a Plastic Surgeon for a consultation. During your visit, the physician takes out his cell phone and takes several pictures of the areas for the surgery. During this process the physician explains that this will be a part of his before and after collection.
Is there a problem with him using his personal cell phone and not a camera dedicated to the medical practice? Did you sign some disclaimer saying photos could be taken for non-medical purposes? How do you feel about what the physician did? Are there any violation(s)? If so, explain. How would you handle this situation? Create a 2-3 page paper to answer the questions in this case study.
.
You are a new PR intern at Apple. Apple is donating 200 iPads to a l.docxShainaBoling829
you are a new PR intern at Apple. Apple is donating 200 Ipads to a local inner-city school to promote technology in education. As a PR intern, you need to get the word out about this event. In your discussion post, compose a tweet (a tweet is 140 characters or less) and a Facebook post (200-250 words) creating awareness for the event.
.
You are a leader of a European country. You want your country to get.docxShainaBoling829
You are a leader of a European country. You want your country to get involved in South America for resources, markets ad trade.write a letter to president monroe of the united states and respond to the monroe doctrine. What steps will you take to complete your intention of getting involved in South America?
.
You are a community health educator and you have been tasked with de.docxShainaBoling829
You are a community health educator and you have been tasked with developing a presentation to be given in a setting to educate an audience on one specific kind of diabetes.
Identify
your audience. Examples include the following:
Senior center
Middle school
A Workplace
Create
a 350- to 700-word resource as a way to share this information. Examples include the following:
A social media page
An information pamphlet
A presentation
Consider
the best method so it is crafted in an appropriate and understandable way for your identified audience.
Choose
from the two following options, which kind of diabetes you'll be reporting on:
Option A: Type I
How society views diabetes (what society thinks it is versus what it actually is, common beliefs and practices)
Signs and symptoms
Compliance with treatment regimens
Impact on health care resources
Option B: Type II
How society views diabetes (what society thinks it is versus what it actually is)
Preventive measures
Making the right decisions to live a healthy life
Compliance with common beliefs
Impact on health care resources
.
You and your team have completed your fieldwork and have a handful o.docxShainaBoling829
You and your audit team have completed your fieldwork for an audit. As a senior staff member who may be promoted to manager, you need to instruct other staff on reviewing for contingent liabilities, letters from client lawyers, and subsequent events before issuing the audit report. This is to ensure nothing significant has occurred between completing fieldwork and reporting.
xxxx, great post. I agree that as technology has grown so has the .docxShainaBoling829
The document discusses how technology and social media have increased media influence over what information the public receives and how they perceive events. It also notes that social media portrays false images that influence dress choices and cause some people to build their lives around social media celebrities rather than being themselves. The document advocates that people should not feel they need to follow the masses or media portrayals and instead be comfortable being themselves.
Yes Richard I agree with you. The American Red Cross has been workin.docxShainaBoling829
Yes Richard I agree with you. The American Red Cross has been working alongside families and communities in Haiti for more than 10 years. When a 7.0 earthquake struck the country in 2010, Americans’ generosity has made this critical work possible. Thanks to donations from across the United States, American Red Cross continue to help Haitians recover from these disasters. They still provide food, water, medical care, sanitation and emergency shelter to families in need. Over the past seven years, they have funded more than 50 hospitals and clinics in Haiti and so much more.They continue working alongside the Haitian Red Cross to ensure that recovery is long-lasting and that families are prepared for future disasters that may come their way
I NEED YOU TO COMMENT FROM THIS POST, NO MORE THAN 150 WORDS NEEDED AND A REFERNCE PLEASE
.
Yet society has in every possible way created the impression that on.docxShainaBoling829
Wink argues that society creates the impression that some people are favored by God while others are rejected, based on attributes like appearance, wealth, gender, etc. There are benefits to going along with this system of unequal social hierarchies, but rejecting it challenges the entire structure. If God does not favor some over others based on accidents of birth, then the social order is a human construct established against God's nature of equality and justice for all.
xxxxx comment 1xxxxx, I believe America only sees leftright, li.docxShainaBoling829
xxxxx comment 1
xxxxx, I believe America only sees left/right, liberal/conservative, one's race/others' race, one's religion/others' religion, etc. To be fair, there are important issues that we do face but the media has pulled both further from the center. This is done to keep us preoccupied in conflict so we ignore what is being done in front of our faces, which is politicians/media/wealthy elites are controlling the government/financial system/media to mold the public's views and what they buy. By them focusing on these secondary issues and differences, we are missing the root problem: money in politics. These legal bribes guarantee that we are not represented in legislation unless enough people oppose the current law.
Comment 2
Nicely said, it is amazing how money can be used to basically buy anything in the world, even our politicians. The Presidency, our Senators and Congressman, Governors, Mayor's and more. This allows for things like the rich getting richer and the poor or course getting poorer. It almost seems like there is no middle class anymore. Money plays a huge role in everyday life. Don't get me wrong, money and politicians has definitely been used in some cases for the good or doing the right thing. We cannot base everything evil or not perfect on money. We just have to be more responsible.
.
WWTC Active Directory DesignWWTC office at New York is largely a.docxShainaBoling829
WWTC Active Directory Design
WWTC office at New York is largely autonomous and few IT personnel to take care of day-to-day IT support activities such as password resets troubleshoot virus problems. You are concerned about sensitive data store in this location. You want to deploy a highly developed OU structure to implement security policies uniformly through GPO automatically at all domains, OU, and workstations.
At this location Windows Server 2012 R2 is required providing the following
10 AD features
:
1.
Use BitLocker encryption technology for devices (server and Work station) disc space and volume.
2.
Enables a BitLocker system on a wire
d network to automatically unlock the system volume during boot (on capable Windows Server 2012 R2 networks), reducing internal help desk call volumes for lost PINs.
3.
Create group policies settings to enforce that either Used Disk Space Only or Full Encryption is used when BitLocker is enabled on a drive.
4.
Enable BranchCache in Windows Server 2012 for substantial performance, manageability, scalability, and availability improvements
5.
Implement Cache Encryption to store encrypted data by default.
This allows you to ensure data security without using drive encryption technologies.
6.
Implement Failover cluster services
7.
Implement File classification infrastructure feature to provide automatic classification process.
8.
IP Address Management (IPAM) is an entirely new feature in Windows Server 2012 that provides highly customizable administrative and monitoring capabilities for the IP address infrastructure on a corporate network.
9.
Smart cards and their associated personal identification numbers (PINs) are an increasingly popular, reliable, and cost-effective form of two-factor authentication. With the right controls in place, a user must have the smart card and know the PIN to gain access to network resources.
10.
Implement Windows Deployment Services to enables you to remotely deploy Windows operating systems. You can use it to set up new computers by using a network-based installation.
Other AD Deliverables
:
Create Active directory infrastructure to include recommended features
Create OU level for users and devices in their respective OU
Create Global, Universal, Local group. Each global group will contain all users in the corresponding department. Membership in the universal group is restrictive and membership can be assigned on the basis of least privileged principle. (For design purpose, you can assume that WTC as a Single Forest with multiple domains).
Create appropriate GPO and GPO policies and determine where they will be applied
.
Wrongful Convictions and the Utilization of Eyewitness Accounts Wr.docxShainaBoling829
Wrongful Convictions and the Utilization of Eyewitness Accounts
Write a 2 to 3 page paper responding to the following: APA FORMAT
Identify the ethical issues within the field of criminal investigation as applied to wrongful conviction based upon tainted or faulty line-ups.
In recent years we have seen many criminal convictions overturned for various reasons. One such reason is the “Eyewitness Account.”
Address the ethical responsibilities of law enforcement in their requirements for fairness, and responsibility to ensure there are no wrongful convictions based upon false identification.
Identify the processes utilized by law enforcement in the identification of suspects.
Consider individuals making identifications, do so in error at times, others intentionally, or are led by law enforcement through improper actions i.e., prejudicial line-ups or photo arrays.
.
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Written Report on Documentary:
Enron: The Smartest Guys in the Room
For this assignment view the video,
ENRON:
The Smartest Guys in the Room,
[1 hr. & 50 min].
Write a critique of the film in 4-5 page double-spaced paper.
Answer each of the following questions in your essay.
The written assessment of
Enron
is due according to Syllabus.
Submit a paper copy in class and also post it on BB website SafeAssign.
2.
Describe the dominant culture of ENRON and the subculture of Enron’s trading group.
3.
Do you believe that Enron’ failure is a result of the behavior of “a few bad men”, or a demonstration of the “dark shadow of the American dream”?
Explain.
4.
What did Skilling say is the only thing that motivates people?
Do you agree or disagree?
5.
Describe the PRC (performance review committee).
Why was it referred to as “rank and yank”?
What was its effect?
What is your opinion of the ethics of the practice?
6.
Describe Enron’s initiative on broadband technology.
7.
What was Arthur Andersen’s conflict of interest in regards to Enron?
What could have been done to prevent this conflict of interest?
8.
How did Skilling treat Fortune author Bethany McLean when she started asking questions about Enron’s financials?
Do you think this was a tactic, and if so, what did he hope to achieve by it?
9.
What are three important “takeaway” messages you learned from this documentary?
.
Written assignment,. please follow instruction..Legislative Prof.docxShainaBoling829
The document provides instructions for a written legislative profile assignment requiring the respondent to research and provide information about various elected officials representing their state and district. This includes identifying a US Senator and House Representative, as well as state-level Senators and House members. For each official, the respondent must provide biographical details, committee assignments, political views supported by quotes, and summaries of speeches found online. The instructions emphasize completing all questions, citing sources, avoiding plagiarism, and ensuring correct grammar, spelling and completeness.
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Written Assignment:
Choose
a Part 121 air carrier
(such as American, Delta, Southwest, etc.) and provide data that shows how that enterprise has successfully employed competitive advantage obtained through the utilization of information technology to win and keep loyal customers or operate more efficiently in the reservations, maintenance, or operations departments. You may provide a historical example that would be found going back several decades. Learning from the past is a great way to succeed in the future.
.
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This document provides instructions for a written assignment to write a 2-3 minute eulogy for a deceased or living person. Students are asked to write a manuscript as if transcribing what they would say at the eulogy, including an creative introduction, supporting details, and conclusion with transitions. They should not record a speech or provide an outline, but instead copy and paste the written word-for-word manuscript.
How to Make a Field Mandatory in Odoo 17Celine George
In Odoo, making a field required can be done through both Python code and XML views. When you set the required attribute to True in Python code, it makes the field required across all views where it's used. Conversely, when you set the required attribute in XML views, it makes the field required only in the context of that particular view.
This document provides an overview of wound healing, its functions, stages, mechanisms, factors affecting it, and complications.
A wound is a break in the integrity of the skin or tissues, which may be associated with disruption of the structure and function.
Healing is the body’s response to injury in an attempt to restore normal structure and functions.
Healing can occur in two ways: Regeneration and Repair
There are 4 phases of wound healing: hemostasis, inflammation, proliferation, and remodeling. This document also describes the mechanism of wound healing. Factors that affect healing include infection, uncontrolled diabetes, poor nutrition, age, anemia, the presence of foreign bodies, etc.
Complications of wound healing like infection, hyperpigmentation of scar, contractures, and keloid formation.
This presentation was provided by Rebecca Benner, Ph.D., of the American Society of Anesthesiologists, for the second session of NISO's 2024 Training Series "DEIA in the Scholarly Landscape." Session Two: 'Expanding Pathways to Publishing Careers,' was held June 13, 2024.
ISO/IEC 27001, ISO/IEC 42001, and GDPR: Best Practices for Implementation and...PECB
Denis is a dynamic and results-driven Chief Information Officer (CIO) with a distinguished career spanning information systems analysis and technical project management. With a proven track record of spearheading the design and delivery of cutting-edge Information Management solutions, he has consistently elevated business operations, streamlined reporting functions, and maximized process efficiency.
Certified as an ISO/IEC 27001: Information Security Management Systems (ISMS) Lead Implementer, Data Protection Officer, and Cyber Risks Analyst, Denis brings a heightened focus on data security, privacy, and cyber resilience to every endeavor.
His expertise extends across a diverse spectrum of reporting, database, and web development applications, underpinned by an exceptional grasp of data storage and virtualization technologies. His proficiency in application testing, database administration, and data cleansing ensures seamless execution of complex projects.
What sets Denis apart is his comprehensive understanding of Business and Systems Analysis technologies, honed through involvement in all phases of the Software Development Lifecycle (SDLC). From meticulous requirements gathering to precise analysis, innovative design, rigorous development, thorough testing, and successful implementation, he has consistently delivered exceptional results.
Throughout his career, he has taken on multifaceted roles, from leading technical project management teams to owning solutions that drive operational excellence. His conscientious and proactive approach is unwavering, whether he is working independently or collaboratively within a team. His ability to connect with colleagues on a personal level underscores his commitment to fostering a harmonious and productive workplace environment.
Date: May 29, 2024
Tags: Information Security, ISO/IEC 27001, ISO/IEC 42001, Artificial Intelligence, GDPR
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How to Setup Warehouse & Location in Odoo 17 InventoryCeline George
In this slide, we'll explore how to set up warehouses and locations in Odoo 17 Inventory. This will help us manage our stock effectively, track inventory levels, and streamline warehouse operations.
The chapter Lifelines of National Economy in Class 10 Geography focuses on the various modes of transportation and communication that play a vital role in the economic development of a country. These lifelines are crucial for the movement of goods, services, and people, thereby connecting different regions and promoting economic activities.
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Iván Bornacelly, Policy Analyst at the OECD Centre for Skills, OECD, presents at the webinar 'Tackling job market gaps with a skills-first approach' on 12 June 2024
2. Equipment
Materials
How to develop your cause and effect diagram: 1. Identify
practice problem you are trying to improve in the effect box. 2.
In each category of causes, (a) people, (b) environment, (c)
materials, (d) methods, and (e) equipment input causes for the
effect. (See example and rubric).
8/19/2019 VERSION A
Template: Failure Modes and Effects Analysis
Step in Process
Failure
Mode
Failure Cause
Failure Effect
Occurrence Likelihood
Detection
Likelihood
Severity
Risk Profile Number
Actions to Mitigate Risk
3.
4.
5. Occurrence Likelihood rate 1-10 (10 means most likely to
occur)
Detection Likelihood rate 1-10 (10 means least likely to be
detected)
Severity rate 1-10 (10 means most likely to cause severe
harm)
To calculate Risk Profile Number: Multiply Occurrence
Likelihood times Detection Likelihood times Severity = Risk
Profile Number
Submit completed FMEA form to assignment link for grading,
place on presentation slide, and summarize FMEA findings in
your presentation slide. (see Practice Problem Analysis
Guidelines and Rubric)
9/12/2019 Version
8
6. Esophageal cancer and smoking
Name
Chamberlin University
PICOT Question
Are men 45 years of age and older (P) who have a one-year
history of smoking or less (I) at an increased risk of developing
esophageal cancer (O) compared with men age 45 and older (P)
who have no smoking history (C)?
Evidence Synthesis of Literature to Address Practice Problem
According to the Cancer Research UK (2020), cancer of
the esophagus is more common in older people. Around 40% of
the members of the population develop esophageal cancer at the
age of 75 and above. The Cancer Research UK (2020) equally
notes that an estimated lifetime risk of being diagnosed with
esophageal cancer us 2% for males and 1% for females in the
United Kingdom. The findings of the Cancer Research UK
(2020) indicate that 59% of esophageal cancer cases are
preventable, but the condition is associated with a number of
risk factors such as tobacco smoking, alcohol intake, and
radiation exposure among other risk factors.
According to a cohort study conducted by Fan et al.
(2008), tobacco smoking and alcohol consumption were
established as the major risk factors for esophageal squamous
7. cell carcinoma (ESCC), especially in the western population.
The study reports many retrospective studies that have
demonstrated a synergic effect of alcohol and smoking in ESCC
risk. Nevertheless, prospective studies on esophageal cancer
especially in high incidence regions are scare and their results
have been inconsistent. Fan et al. (2008) equally reports a
cohort study that was conducted in Linxian, China, which found
a week association between smoking and ESCC but failed to
demonstrate statistical significance association with alcohol
intake. The study observed association between smoking and
esophageal adenocarcinoma (EAC), but the risk is weaker than
that for ESCC.
Fan et al. (2008) states that there is little information from
the prospective studies on the potential role of tobacco in
esophageal cancer in the high-risk populations, especially older
men. The researchers examined the association between the risk
factor to the development of esophageal cancer alone and in
combination and the risk of development of esophageal cancer
in the Shangai Cohort study, which enrolled more than eighteen
thousand middle aged and older men and found a week
association between smoking and development of esophageal
cancer.
Contrary to the findings of Fan et al. (2008), a systematic
review and Meta-analysis conducted by Wang et al. (2017)
indicates that smoking strongly increases the risk of esophagus
squamous cell carcinoma and moderately increases the risk of
esophageal adenocarcinoma. Nevertheless, the researchers were
quick to point out that the manner with which smoking cessation
influence esophageal cancer risk across histological subtypes,
geographical regions and time latencies is not clear. The studies
analyzed by Wang et al. (2017) were systematically searched on
Embase, Medline, Web of Science, ClinicalTrials.gov, and
Cochrane Library. From the studies, polled estimates of risk
ratios (RRs) were derived using a random effect model . The
results of the study indicated that among the 15009 research
articles searched, 52 fulfilled the inclusion criteria. Using the
8. nonsmokers as the reference, the risk of ESCC was higher is
current smokers than in former smokers. When comparing with
the current smokers, a strong reduction was evident after five or
more years and became stronger after ten more years. Wang et
al. (2017) therefore concluded the smoking cessation tie-
dependently decreases risk of ESCC, particularly in western
populations, while it has limited influence in the risk of
esophageal adenocarcinoma.
According to Kuang et al. (2016), esophageal cancer is the
sixth leading cause of cancer mortality in the world. According
to the official statistics of the United States, more than 18,000
cases of esophageal cancer were newly diagnosed and 15,000
deaths occurred from the condition in 2014, which represented
5% of all cancer deaths. ESCC and esophageal adenocarcinoma
(EA) are the two main histological subtypes of esophagus
cancer. Kuang et al. (2016) explains that within the recent
decades, in some places such as in Europe and in North America
incident and mortality of ESCC has decreased. Nevertheless, in
other areas such as in Asia, especially in China, ESCC still
occupies the vast majority of EC with most patients with
oesophageal cancer in locally advanced or metastatic disease at
the time of diagnosis.
Kuang et al. (2016) states that sufficient population based
case-control and cohort studies have indicated that
gastroesophageal reflux disease (GERD), cigarette smoking, and
obesity are the main established risk factors for developing
esophageal cancer. The researchers indicate that studies have
shown that compared with non-smokers, ESCC incidence risk is
increased by approximately 3 to 7 fold in current smokers, and
the risk of esophageal squamous cell carcinoma is greater than
adenocarcinoma. Nevertheless, the relationship between
smoking exposure and the prognosis of patients with esophagus
cancer is still not clear. Kuang et al. (2016) concluded their
studies by indicating that the pooled results support the
existence of harmful effects of smoking on survival even after
esophagus cancer diagnosis. The researchers equally indicate
9. that tobacco control and smoking cessation should be
considered as an important part of a long-term treatment of
esophagus cancer. Moreover, large population based and well -
designed studies would be critical to further clarify the benefit
of smoking cessation for esophageal cancer patients.
Appraisal of the Evidence to Address Selected Problem
Cancer Research UK (2020) is a reputable source that
provides statistically verifiable information with regards to the
prevalence, incidence and management of cancer, not only in
the United States, but in the rest of the world. With regards to
the PICOT question, Cancer Research UK (2020) provides
valuable information on the relationship between esophageal
cancer and age as well as between esophageal cancer and
gender. The evidence suggest that there is a positive association
between development of esophageal cancer with increase in age
while at the same time, the source indicate that men are two
times as likely to develop esophageal cancer as compared to
women. In essence, the source answers part of the PICOT
question, by affirming that incidence of esophageal cancer is
likely to be higher among men who are 45 years and above.
Nevertheless, the source does not provide concrete evidence on
the relationship between esophageal cancer and tobacco
smoking.
Fan et al. (2008) provides an insightful information, which
is critical to the answering of the PICOT question. The
researchers conducted a large population based cohort study
that examined the relationship between smoking, alcohol use
and diet in the occurrence of esophageal cancer. By conducting
a large population based cohort study, the researchers were able
to increase the representativeness of the study, thus making the
findings of the study to have a high index of validity. The study
seeded to affirm the fact that men who are 45 years of age and
older who have a history of smoking are at an increased risk of
developing esophageal cancer compared with men age 45 and
older who have no smoking history.
Wang et al. (2017) relied on a systematic review and meta-
10. analysis in an attempt to understand the relationship between
smoking cessation and the risk of esophageal cancer. In as much
as the researchers did not follow the typical cause effect method
in examination of the relationship between smoking and
esophageal cancer, the retrospective study was important in
substantiating the claims in the PICOT question. First, Wang et
al. (2017) used a large sample of research materials to make a
conclusion on their findings. One of the most significant
findings by the researchers was that tobacco smoking was
strongly associated with an increased risk of esophageal cancer.
This finding implies that men of 45 years of age and older who
have a history of smoking are at an increased risk of developing
esophageal cancer compared with men age 45 and older who
have no smoking history.
Kuang et al. (2016) equally relied on the evidence of a
systematic review and meta-analysis to examine the influence of
smoking on esophageal cancer. The study verified that smoking
is a well-known major risk factor in the development of
esophageal cancer. Nevertheless, the population of study for
Kuang et al. (2016) was the patients with esophageal cancer.
The researchers were able to prove that for those patients with
pre-existing esophageal cancer, smoking leads to higher cases
of mortality as compared to patients with esophageal cancer but
are non-smokers. In as much as the evidence presented by
Kuang et al. (2016) has many confounders such as the staging of
the cancer, the type of treatment and the metastatic level of the
disease, the researchers were able to prove that smoking has a
potentially increased risk in worsening cancer status or in the
development of cancer.
Translation Path
The findings of this paper are critical in development of
knowledge base that can be used by healthcare providers to
conduct appropriate patient and family educations on the
implications of smoking and the development of esophageal
cancer. The findings of this paper equally open windows for
future research into the subject matter and enhance the
11. understanding of esophageal cancer and its prevention.
Conclusion
the paper finds a relationship between esophageal cancer and
smoking. The findings of this paper equally validate the PICOT
question that men 45 years of age and older who have a one-
year history of smoking or less (I) are at an increased risk of
developing esophageal cancer (O) compared with men age 45
and older (P) who have no smoking history (C)?
References
Cancer Research UK. (2020). Oesophageal cancer risk.
https://www.cancerresearchuk.org/health-professional/cancer-
statistics/statistics-by-cancer-type/oesophageal-cancer/risk-
factors#heading-One
Kuang J, Jiang Z, Chen Y, Ye W, Yang Q, Wang H, & Xie D.
(2016). Smoking Exposure and Survival of Patients with
Esophagus Cancer: A Systematic Review and Meta-Analysis.
https://www.hindawi.com/journals/grp/2016/7682387/
Wang Q, Xie S, Li W, & Lagergren J. (2017). Smoking
Cessation and Risk of Esophageal Cancer by Histological Type:
12. Systematic Review and Meta-analysis. Journal of the National
Cancer Institute, Volume 109, Issue 12, December 2017,
djx115, https://doi.org/10.1093/jnci/djx115
Fan Y, Yuan J, Wang R, Gao Y, & Yu1 M. (2008). Alcohol,
Tobacco and Diet in Relation to Esophageal Cancer: The
Shanghai Cohort Study.
Week 6: NR706 Practice Problem Analysis and Presentation
Guidelines
Purpose
The purpose of this assignment is to critically evaluate a
practice problem. This assignment builds on the Week 4
assignment: Translation Science Project. Information used in
the Week 4 assignment may be used as the basis for this
assignment. The goal of the assignment is to develop a deeper
understanding of the practice issue, using continuous quality
improvement tools; specifically, a failure mode & effect
analysis (FMEA) of the selected practice problem and an
Ishikawa (fishbone) cause and effect diagram to analyze,
improve, or mitigate related risks. This assignment will allow
for the application of the DNP Essential IV sub-competencies
through sequential development of workflow steps in relation to
a practice problem and promotion of presentation skills.
Assignment content supports the professional formation,
communication, and dissemination skills relevant to the DNP
practice scholar.
This assignment has four components:
· first, identify a practice problem stated in PICOT format;
· second, conduct a failure mode & effect analysis of the
practice problem;
· third, develop an Ishikawa (fishbone) cause and effect diagram
to analyze, improve, or mitigate related risks
· and fourth, create a professional power point presentation with
speaker notes for each slide to disseminate this information.
Course Outcomes
This assignment enables the student to meet the following
13. course outcomes:
· CO 4: Evaluate the types of healthcare information systems,
knowledge-based systems, and patient care technology and the
impact on patient safety, quality of care and outcomes
measurement. (PO 7)
· CO 5: Appraise consumer health information sources for
accuracy, timeliness, and appropriateness. (PO7)
Due Date(s)
The assignment title is due by Sunday 11:59 p.m. MT at the end
of Week 6. The Late Assignment Policy applies to this
assignment.
Total points possible: 250
Preparing the Assignment
Follow these guidelines when completing each compone nt of the
assignment. Contact your course faculty if you have questions.
Consider using the same practice problem identified in Week 4:
Translation Science Project, including the practice problem,
PICOT construction, and background/significance of the
problem. Be sure to incorporate faculty feedback from the Week
4 assignment to maximize performance.
2) Review the examples of the Failure Mode and Effect
Analysis (FMEA) and Ishikawa (fishbone) Diagram in Week 4,
Explore page 2, Evidence-Based Practice: Improving Outcomes.
Use the Week 6 Practice Problem Analysis PowerPoint
Template to complete the PowerPoint Presentation. (Links to an
external site.)
Use the Failure Modes and Effects Analysis (FMEA) (Links to
an external site.) and Ishikawa (fishbone) Diagram template A
(Word 2016 or higher) (Links to an external site.) or Ishikawa
(fishbone) Diagram template B (Older version of Word) (Links
to an external site.) or create your own fishbone diagram
addressing the required five areas: (a) people, (b) environment,
(c) materials, (d) methods, and (e) equipment to complete these
components of the assignment. If you need to update to the
current version of Word, click here.
Please submit to the assignment link the completed Week 6
14. Practice Problem Analysis PowerPoint Presentation with
speaker notes for each slide integrating failure mode & effect
analysis and fishbone diagrams into the powerpoint answering
associated questions. Upload the finished powerpoint with
speaker notes to assignment link.
3) Include the following components.
a) Introduction (1 slide)
i) Title of Practice Problem Analysis and Presentation
ii) Student Name
iii) Assignment Title
iv) Professor Name
b) Practice Problem Identification (1-3 slides)
i) State the Practice Problem in PICOT format (1 slide)
ii) Identify all PICOT components
iii) Describe the Background/Significance of the Practice
Problem (1-2 slides) (cited)
iv) Identify inclusion criteria for the population
v) Identify exclusion criteria for the population
c) Failure Modes and Effects Analysis (1-2 slides) Identify
three steps in the practice problem process with potential
breakdown or process gaps
i) Identify at least one potential error that could occur at each
of the three process steps (failure mode)
ii) Identify at least one possible cause of failure at each of the
three process steps (failure cause)
iii) Identify at least one adverse consequence for each failure
identified (failure effect) (see example in course Week 4)
iv) Using a scale of 1-10, rate the likelihood of occurrence of
failure at each process step
v) Using a scale of 1-10, rate the likelihood of detection of
failure at each process step
vi) Using a scale of 1-10, rate the likelihood of severity or
harm if failure were to occur
vii) Calculate the risk profile number (multiply the score
related to the likelihood of occurrence of failure x the score
related to the likelihood of detection of failure x the likelihood
15. of severity or harm if failure were to occur.
viii) Place completed FMEA form on powerpoint presentation
and summarize analysis
d) Ishikawa (Fishbone) Cause and Effect Diagram (1 Slide)
i) Identify people involved in the practice problem
ii) Identify the environment in which the practice problem
occurs
iii) Identify the materials used
iv) Identify the methods used
v) Identify equipment used
vi) Summarize cause and effect analysis
e) Conclusion (1 slide)
i) Summarize the purpose and findings of the analysis
ii) Provide and justify the main conclusions
iii) Draw inferences from the quality improvement analysis
f) References (1 slide)
i) Include in-text citations within the PowerPoint
ii) Provide complete matching references in APA format
iii) Includes a minimum of 4 scholarly sources
g) PowerPoint Presentation
i) Uses PowerPoint Template provided
ii) Uses Failure Modes & Effects Analysis Template Provided
iii) Uses Ishikawa Fishbone Cause & Effects Diagram Provided
(Version A or B acceptable or create your own diagram
addressing required areas)
iv) Presentation includes no more than 14 slides
v) Grammar and Mechanics are free of errors
h) Speaker Notes on PowerPoint Presentation: Create a
professional power point presentation of the above components
with speaker notes for each slide in which the Practice Problem
Analysis is explained
i) Provide clear and easily readable slide presentation
ii) Capture all slide components and answers questions
iii) Present content with legible, comprehensive notes
Rubric
Week 6: NR706: Practice Problem Analysis and Presentation
16. Week 6: NR706: Practice Problem Analysis and Presentation
Criteria
Ratings
Pts
This criterion is linked to a Learning OutcomeIntroduction
Requirements:
1. Provides Title of Presentation
2. Introduces Self
3. Identifies Assignment Title
4. Identifies Professor Name
20 pts
Highest Level of Performance
Includes no fewer than 4 requirements.
18 pts
Very Good or High Level of Performance
Includes no fewer than 3 requirements.
16 pts
Acceptable Level of Performance
Includes no fewer than 2 requirements.
0 pts
Failing Level of Performance
Includes 1 or fewer requirements.
20 pts
This criterion is linked to a Learning OutcomePractice Problem
Identification
Requirements:
1. States the Practice Problem in PICOT format
2. Identifies all PICOT components
3. Describes the Background/ Significance of the Practice
Problem (cited)
4. Identifies inclusion criteria for the population.
5. Identifies exclusion criteria for the population
40 pts
Highest Level of Performance
Includes no fewer than 5 requirements.
17. 36 pts
Very Good or High Level of Performance
Includes no fewer than 4 requirements.
32 pts
Acceptable Level of Performance
Includes no fewer than 3 requirements.
0 pts
Failing Level of Performance
Includes 2 or fewer requirements.
40 pts
This criterion is linked to a Learning OutcomeFailure Modes &
Effects Analysis
Requirements:
1. Identifies at least one potential error (failure mode) for each
of the three process steps.
2. Identifies at least one potential error (failure cause) for each
of the three process steps.
3. Identifies at least one potential adverse consequence (failure
effect) for each of the three process steps
4. Rate the likelihood of occurrence of failure at each process
step
5. Rate the likelihood of detection of failure at each process
step
6. Rate the likelihood of severity or harm if failure were to
occur
7. Calculates the risk profile number
8. Summarizes FMEA analysis
40 pts
Highest Level of Performance
Includes no fewer than 8 requirements.
36 pts
Very Good or High Level of Performance
Includes no fewer than 7 requirements.
32 pts
Acceptable Level of Performance
18. Includes no fewer than 6 requirements.
0 pts
Failing Level of Performance
Includes 5 or fewer requirements.
40 pts
This criterion is linked to a Learning OutcomeIshikawa
Fishbone Cause & Effects Diagram
Requirements:
1. Identifies people involved in the practice problem
2. Identifies the environment in which the practice problem
occurs
3. Identifies the materials used
4. Identifies methods used
5. Identifies equipment used
6. Summarizes cause and effect analysis
40 pts
Highest Level of Performance
Includes no fewer than 6 requirements.
36 pts
Very Good or High Level of Performance
Includes no fewer than 5 requirements.
32 pts
Acceptable Level of Performance
Includes no fewer than 4 requirements.
0 pts
Failing Level of Performance
Includes 3 or fewer requirements.
40 pts
This criterion is linked to a Learning OutcomeConclusion
Requirements:
1. Summarizes the purpose and findings of the analysis
2. Provides and justifies the main conclusions
3. Draw inferences from the quality improvement analysis
20 pts
19. Highest Level of Performance
Includes no fewer than 3 requirements.
18 pts
Very Good or High Level of Performance
Includes no fewer than 2 requirements.
16 pts
Acceptable Level of Performance
Includes 1 requirement.
0 pts
Failing Level of Performance
No requirements for this section presented.
20 pts
This criterion is linked to a Learning OutcomeReferences
Requirements:
1. Includes in-text citations within the PowerPoint
2. Provide complete matching references in APA format
3. Includes a minimum of 4 scholarly sources
20 pts
Highest Level of Performance
Includes no fewer than 3 requirements.
18 pts
Very Good or High Level of Performance
Includes no fewer than 2 requirements.
16 pts
Acceptable Level of Performance
Includes 1 requirement
0 pts
N/A
N/A
20 pts
This criterion is linked to a Learning OutcomePowerPoint
Presentation
PowerPoint Presentation
20. Requirements:
1. Uses PowerPoint Template provided
2. Uses Failure Mode & Effects Analysis Template Provided
3. Uses Ishikawa Fishbone Cause & Effects Diagram
4. Presentation includes no more than 14 slides.
5. Grammar and Mechanics are free of errors
30 pts
Highest Level of Performance
Includes no fewer than 5 requirements.
27 pts
Very Good or High Level of Performance
Includes no fewer than 4 requirements.
24 pts
Acceptable Level of Performance
Includes no fewer than 3 requirements.
0 pts
Failing Level of Performance
Includes 2 or fewer requirements.
30 pts
This criterion is linked to a Learning OutcomeSpeaker Notes on
PowerPoint Presentation
1. Provides clear and easily readable slide presentation
2) Addresses all slide components and questions
3) Presents legible speaker notes supplementing slide content
40 pts
Highest Level of Performance
Includes no fewer than 3 requirements.
36 pts
Very Good or High Level of Performance
Includes no fewer than 2 requirements.
32 pts
Acceptable Level of Performance
Includes 1 requirement.
0 pts
Failing Level of Performance
21. No requirements for this section presented.
40 pts
Total Points: 250
Practice Problem Title Here
Name and Credentials Here
NR 706 Week 6 Practice Problem Analysis Assignment
Instructor’s Name Here
Revised 9/12/2019
Practice Problem Identification
State the Practice Problem in PICOT format (1 slide)
Identify all PICOT components
2
Background/Significance
Evidence from research explaining background/significance of
practice problem (no more than 1-2 slides – cited in APA)
Include inclusion criteria for population of interest
Include exclusion criteria for population of interest
Failure Mode & Effect Analysis (FMEA)
Place FMEA form here, answer questions below, and summarize
analysis. (1-2 slides)
Place diagram on slide and then answer:
22. Which step is the most important to focus resources? The one
with the highest risk profile number?
How did this analysis benefit your understanding of your
practice problem.
Summarize analysis
4
Ishikawa (Fishbone) Diagram
Place diagram here, answer questions below, and summarize
analysis. (1-2 slides)
Place diagram on slide and then answer:
Of the five categories which are the most important to focus on
for your practice problem and why?
How did this analysis benefit your understanding of your
practice problem.
Summarize your analysis
Conclusion
Summarize the purpose and findings of the analysis
Provide and justify the main conclusions
Draw inferences from the quality improvement analysis
6
References
23. Includes in-text citations throughout the PowerPoint
Presentation
Provides complete matching references in APA format
Grammar and Mechanics throughout the PowerPoint
Presentation are free of errors
Note: This presentation should be submitted to the assignment
link
7