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This document provides information about Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's disease. It defines ALS as a condition where the motor neurons that control muscle movement start to break down and die, preventing the brain from sending signals to the muscles so they cannot move. An estimated 30,000 Americans have ALS at any given time. While the cause is unknown, some scientists believe excessive levels of the neurotransmitter glutamate may damage and kill motor neurons through a chain reaction effect. The document outlines how neurotransmitters normally work and the theory that too much glutamate causes this chain reaction leading to motor neuron death and muscle paralysis. ALS can affect people of any age, race or background and
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This document provides an overview of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. It defines ALS as a disease that causes the loss of motor neurons in the brain and spinal cord, preventing communication between the brain and muscles and resulting in muscle weakening and atrophy. The document discusses how ALS affects basic functions like walking, eating, and breathing. It notes that while the cause of ALS is unknown, neurotransmitter imbalances may play a role by overstimulating neurons and eventually killing them. The document also provides statistics on ALS prevalence and life expectancy after diagnosis, as well as profiles of famous individuals like Lou Gehrig and Stephen Hawking who lived with ALS.
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This document provides an overview of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. It defines ALS as a disease that causes the loss of motor neurons in the brain and spinal cord, preventing communication between the brain and muscles and resulting in muscle weakening and atrophy. The document discusses how ALS affects basic functions like walking, eating, and breathing. It notes that while the cause of ALS is unknown, neurotransmitter imbalances may play a role by overstimulating neurons and eventually killing them. The document also provides statistics on ALS prevalence and life expectancy after diagnosis, as well as profiles of famous individuals like Lou Gehrig and Stephen Hawking who lived with ALS.
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English als powerpoint
This document provides information about amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. It discusses that ALS is a progressive neurodegenerative disease that affects motor neurons in the brain and spinal cord, leading to muscle weakness, paralysis, and eventually death. Early symptoms can include muscle weakness, twitching, slurred speech, and difficulty breathing. There is no known cure for ALS, but some treatments can help manage symptoms and prolong survival for a few months. Donations can help support research to find an effective treatment for ALS.
MOTOR NEURON DISEASE.pptx
Motor neuron diseases are a group of neurodegenerative disorders that progressively cause nerves in the brain and spinal cord to lose function, affecting voluntary muscle movement. The most common type in adults is amyotrophic lateral sclerosis (ALS), which affects both upper and lower motor neurons. There is no cure and treatments focus on managing symptoms and maximizing independence. Prognosis depends on the specific type of motor neuron disease and age of onset, with some forms being fatal and others non-fatal but still reducing quality of life over time.
ALS Research Papers
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Motor neuron disease.pptx new
Motor neuron diseases are a group of rare neurodegenerative disorders that progressively cause nerves in the brain and spinal cord to lose function, affecting voluntary muscle movement. The most common type in adults is amyotrophic lateral sclerosis (ALS), which affects both upper and lower motor neurons. There is no cure for motor neuron diseases, so treatment focuses on managing symptoms and maximizing quality of life through supportive care, rehabilitation, and FDA-approved drugs that may slow progression. Prognosis depends on the specific type of motor neuron disease and age of onset, with some forms being fatal and others non-fatal but still impacting quality of life over time.
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This document provides an overview of motor neuron disease (MND), including:
- MND is a group of conditions that cause motor neurons in the brain and spinal cord to degenerate, affecting movement, speaking, swallowing and breathing.
- There are two types of motor neurons - upper motor neurons in the brain and lower motor neurons in the spinal cord.
- Common types of MND include amyotrophic lateral sclerosis (ALS), primary lateral sclerosis, progressive bulbar palsy, progressive muscular atrophy, and spinal muscular atrophy.
- Symptoms vary but can include muscle weakness, wasting, spasticity, and difficulties with speech, swallowing and breathing. Current treatment focuses on
21 June: The Global Day for Amyotrophic Lateral Sclerosis
ALS is a progressive neurological disease that causes the motor neurons controlling voluntary muscles to break down and die. This results in worsening muscle weakness, atrophy, and spasticity over time. There is no cure for ALS, but symptoms can be treated to prolong survival and quality of life. The cause is largely unknown, though some genetic factors have been identified. Most people live 3-5 years after diagnosis but about 10% of cases are inherited and can have longer survival times. Research continues toward finding effective treatments that target the underlying causes and pathways of the disease.
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Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's Disease, is a progressive neurodegenerative disease that affects nerve cells in the brain and spinal cord. As the motor neurons die, it leads to the loss of ability to initiate and control muscle movement. Early symptoms include increasing muscle weakness, especially in the arms and legs, as well as speech, swallowing, and breathing difficulties. While the cause is unknown, it progressively leads to paralysis as muscles atrophy from lack of signals from motor neurons. There is currently no cure, but one FDA-approved drug can modestly slow progression and other potential treatments are being studied. Devices and therapies can help manage symptoms and prolong survival, though each person
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The nervoussystem
The nervous system contains the brain, spinal cord, and peripheral nerves. It is composed of neurons, which are cells that contain a cell body, nucleus, axon, and dendrites. Neurons are surrounded by myelin and connected through synapses, allowing electrical signals to pass from one neuron to the next through the release of chemicals. Damage to neurons from accidents, drugs, alcohol, or diseases can disrupt these connections and lead to neurological disorders.
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Kat...
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TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Katzung, Verified Chapters 1 - 66, Complete Newest Version.
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TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Katzung, Verified Chapters 1 - 66, Complete Newest Version.
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Katzung, Verified Chapters 1 - 66, Complete Newest Version.Journal Article Review on Rasamanikya
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Neuromuscular diseases by aayupta mohanty
The document discusses several neuromuscular disorders including amyotrophic lateral sclerosis (ALS), multiple sclerosis, and muscular dystrophy. It provides details on ALS such as its symptoms, causes, risk factors, and complications. ALS causes motor neurons to break down and leads to muscle weakness and atrophy. It typically begins in the hands, feet or limbs and eventually affects movement, speech, swallowing and breathing. While most cases have no known cause, genetic mutations and environmental factors may play a role. Complications include breathing and eating problems as well as potential dementia. Tests like EMGs, MRIs and biopsies can help diagnose ALS and rule out other conditions.
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Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that affects motor neurons, leading to their degeneration and death. This causes muscles to weaken and atrophy, resulting in paralysis. Eventually, respiratory muscles are affected and the disease becomes fatal. ALS has causes linked to glutamate toxicity, mutations in the SOD1 gene, and oxidative stress damaging motor neurons. There is no cure for ALS and available treatments can only moderately slow progression of the disease.
English als powerpoint
This document provides information about amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. It discusses that ALS is a progressive neurodegenerative disease that affects motor neurons in the brain and spinal cord, leading to muscle weakness, paralysis, and eventually death. Early symptoms can include muscle weakness, twitching, slurred speech, and difficulty breathing. There is no known cure for ALS, but some treatments can help manage symptoms and prolong survival for a few months. Donations can help support research to find an effective treatment for ALS.
MOTOR NEURON DISEASE.pptx
Motor neuron diseases are a group of neurodegenerative disorders that progressively cause nerves in the brain and spinal cord to lose function, affecting voluntary muscle movement. The most common type in adults is amyotrophic lateral sclerosis (ALS), which affects both upper and lower motor neurons. There is no cure and treatments focus on managing symptoms and maximizing independence. Prognosis depends on the specific type of motor neuron disease and age of onset, with some forms being fatal and others non-fatal but still reducing quality of life over time.
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Motor neuron disease is a serious neurological disorder that causes the motor neurons controlling muscles of movement, speech, swallowing and breathing to deteriorate over time. The main types are ALS, progressive bulbar palsy and progressive muscular atrophy. There is no cure and treatment focuses on managing symptoms to maintain quality of life. The drug riluzole can extend life by a few months but does not relieve symptoms. As motor neurons die, patients gradually lose physical function until they become paralyzed. Outcomes depend on the type and age of onset, with some forms being less deadly and progressing slowly.
Motor neuron disease.pptx new
Motor neuron diseases are a group of rare neurodegenerative disorders that progressively cause nerves in the brain and spinal cord to lose function, affecting voluntary muscle movement. The most common type in adults is amyotrophic lateral sclerosis (ALS), which affects both upper and lower motor neurons. There is no cure for motor neuron diseases, so treatment focuses on managing symptoms and maximizing quality of life through supportive care, rehabilitation, and FDA-approved drugs that may slow progression. Prognosis depends on the specific type of motor neuron disease and age of onset, with some forms being fatal and others non-fatal but still impacting quality of life over time.
ALS ( Amyotrophic Lateral Sclerosis) / Lou Gehrig's Disease
A PPT made by Siddharth Rajah a biology student in his high school on the deadly nervous disease called ALS. It has affected many people like Stephen Hawking. Want to know more about this? You can see my PPT on it which I made for my Grade 11 Biology Project.
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The document discusses the human nervous system. It describes the nervous system as composed of the brain, spinal cord, and peripheral nerves. The brain is divided into three main sections - the cerebrum, cerebellum, and brain stem. Neurons transmit signals through electrical and chemical processes. Neurotransmitters help facilitate communication between neurons. Diseases like Alzheimer's, multiple sclerosis, ALS, and Huntington's can impact the nervous system by damaging neurons or myelin sheaths. Protecting the brain from injury is important for preventing loss of function.
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Jane Paberit, a woman from Estonia, was diagnosed with ALS in 2017. Her diagnosis and decision to seek assisted suicide in Switzerland sparked public discussions in Estonia about issues like euthanasia, palliative care, and what constitutes a dignified end of life. ALS is a rapidly progressive nervous system disease that leads to loss of muscle function and death, with about 20-25 new cases diagnosed in Estonia each year. Jane's illness progressed quickly, making daily tasks difficult, and she chose assisted suicide rather than prolonging her life through medication.
003 Motor Neuron Disease.pptx
This document provides an overview of motor neuron disease (MND), including:
- MND is a group of conditions that cause motor neurons in the brain and spinal cord to degenerate, affecting movement, speaking, swallowing and breathing.
- There are two types of motor neurons - upper motor neurons in the brain and lower motor neurons in the spinal cord.
- Common types of MND include amyotrophic lateral sclerosis (ALS), primary lateral sclerosis, progressive bulbar palsy, progressive muscular atrophy, and spinal muscular atrophy.
- Symptoms vary but can include muscle weakness, wasting, spasticity, and difficulties with speech, swallowing and breathing. Current treatment focuses on
21 June: The Global Day for Amyotrophic Lateral Sclerosis
ALS is a progressive neurological disease that causes the motor neurons controlling voluntary muscles to break down and die. This results in worsening muscle weakness, atrophy, and spasticity over time. There is no cure for ALS, but symptoms can be treated to prolong survival and quality of life. The cause is largely unknown, though some genetic factors have been identified. Most people live 3-5 years after diagnosis but about 10% of cases are inherited and can have longer survival times. Research continues toward finding effective treatments that target the underlying causes and pathways of the disease.
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The document provides an overview of Alzheimer's disease including its causes, symptoms, diagnosis and potential treatments. It discusses how the disease is characterized by progressive cognitive decline and brain cell loss and death. The main causes proposed are the amyloid hypothesis, which suggests beta-amyloid plaques are fundamental, and the cholinergic hypothesis, which implicates reduced acetylcholine levels. The mechanisms involve plaque and tangle formations that disrupt cell signaling in the brain and its neuron transport system.
Document
Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's Disease, is a progressive neurodegenerative disease that affects nerve cells in the brain and spinal cord. As the motor neurons die, it leads to the loss of ability to initiate and control muscle movement. Early symptoms include increasing muscle weakness, especially in the arms and legs, as well as speech, swallowing, and breathing difficulties. While the cause is unknown, it progressively leads to paralysis as muscles atrophy from lack of signals from motor neurons. There is currently no cure, but one FDA-approved drug can modestly slow progression and other potential treatments are being studied. Devices and therapies can help manage symptoms and prolong survival, though each person
Multiple Sclerosis (MS)
Multiple Sclerosis (MS) is a disease of the central nervous system that affects over 400,000 people in the United States. MS occurs when the immune system attacks the protective myelin sheath surrounding the nerve fibers. This damages communication between the brain and body. Symptoms vary depending on location of lesions in the brain, spinal cord, or optic nerves and can include vision issues, mobility problems, numbness, and more. While there is no cure for MS, treatments aim to manage symptoms, speed recovery from attacks, and slow disease progression.
Motor neuron disease- an overview.
The document provides an overview of motor neuron disease (MND), including what it is, who it affects, types, symptoms, causes, diagnosis, treatment and management. MND is a group of neurodegenerative diseases that causes motor neurons in the brain and spinal cord to degenerate and die, leading to progressive muscle weakness. There are four main types depending on which motor neurons are affected. While there is no cure, early diagnosis and multidisciplinary care can help manage symptoms and maximize quality of life for those living with MND. Raising awareness of MND is important for improving understanding and care of those impacted by the disease.
ALZHEIMER’S DISEASE.pptx
Alzheimer's disease is a progressive neurologic disorder that causes atrophy of brain cells, leading it to cell death. it is degenerative and progressive illness. Increase in age with sedentary lifestyle and lack of brain storming activities are indirectly leading to mental disorders with cognitive disruptions like dementia and lading up into Alzheimer's, which makes life miserable of client due to dependency. It is essential to keep the elderly active physiologically as well as psychologically. Statistical data of several studies shows the rise in the cases of Alzheimer's disease, which is the highlighting point of concern. Due to increased digitalization and decreased socialization among the human species throughout globe is leading to increased in risk of getting cognitive deficits.
The Nervous System.ppt
The nervous system is composed of neurons, which are cells that transmit signals through electrical and chemical processes. Neurons are connected at junctions called synapses, where an electrical signal in one neuron causes it to release chemicals that allow the signal to cross to the next neuron. There are around 100 billion neurons in the human brain that connect through trillions of synapses. Damage to neurons from accidents, drugs, alcohol or diseases can disrupt neural connections and cause neurological problems.
The nervoussystem
The nervous system contains the brain, spinal cord, and peripheral nerves. It is composed of neurons, which are cells that contain a cell body, nucleus, axon, and dendrites. Neurons are surrounded by myelin and connected through synapses, allowing electrical signals to pass from one neuron to the next through the release of chemicals. Damage to neurons from accidents, drugs, alcohol, or diseases can disrupt these connections and lead to neurological disorders.
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Final Project
- 1. Amyotrophic Lateral Sclerosis Amyotrophic Lateral Sclerosis ALS Lou Gehrig’s Disease what’s in a name ? a myo trophic lateral sclerosis “without” “muscle” “nourishment” “side (of the spinal cord)” “hardening” or “scarring” So, Amyotrophic means that the muscles in the body are losing nourishment. When muscles lose nourshment, they become weaker and smaller. Did you walk to school today? Eat lunch? Breathe? All of these things become difficult when you have ALS.
- 2. Motor neurons are nerve cells that control muscle movement (They aren’t quite like trucks. They don’t move.) WITHOUT ALS WITH ALS motor neurons motor neurons exist in the brain and spinal cord start to break down, and eventually die motor neurons pass messages from the brain to the muscles If the motor neurons are dead, the brain can’t send signals to the muscles When the messages reach the muscles, they tell the muscles Because the motor neurons are not sending the brain’s messages to the muscles, the person how to move cannot move
- 3. who has ALS? RICK FRIEDMAN / CORBIS 30,000 Americans have ALS at this very moment - MLB Photos / Getty Images That’s almost enough people to fill Fenway Park during a game. LOU GEHRIG Lou Gehrig, a New York Yankees German-American baseball player, is the a famous figure in history to have been diagnosed with ALS.l One of the most common names for ALS, Lou Gehrig’s Disease, 1903-1941 Stephen Hawking is an English physicist at the University of Cambridge. He was diagnosed at the age of 21, but lives today, at the age of 71. 1942- Dan Kitwood / Getty Images Stephen Hawking
- 4. WHO develops als? Most people who develop ALS are between the ages of 40 and 70 Patients are expected to live 2-5 years longer after they are diagnosed. however, ALS occurs throughout the world without racial ethnic socioeconomic boundaries
- 5. so how do people get ALS ? the bad news No one is really sure. the good news Some people have ideas. Some scientists from Johns Hopkins Universtiy say that ALS has a lot to do with something called neurotransmitters neurotransmitters are a lot like your iPhone, but instead of sending iMessages to friends, they send messages to specific cells just like text messages too many neurotransmitters is a bad thing. )You want to have just the right amount(
- 6. how NEUROTRANSMITTERS work 1 An electrical signal enters the A XON NEUROTRANSMITTERS are held inside V E S IC L E S 2 The signal causes the VESICLE to release the NEUROTRANSMITTERS The other cell receives the NEUROTRANSMITTERS and the message 3
- 7. how NEUROTRANSMITTERS work WITH ALS The scientists think that sometimes, in some people, there are too many glutamate neurotransmitters ) glutamate is just one type of ( NEUROTRANSMITTER Remember? too many neurotransmitters is a bad thing.
- 8. = Long story short This causes a chain effect That KILLS motor neurons And if motor neurons are dead, muscles cannot move does this sound familiar ? (Hint: check back to the second page!)
- 9. There is a lot that is still unknown about ALS, and life with ALS can be hard. But there’s hope. Stephen Hawking once said “ I have had motor neuron disease for practically all my adult life. Yet it has not prevented me from having a very attractive family and being successful in my work... I have been lucky that my condition has progressed more slowly than is often the case. But it shows that one need not lose hope. “