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Slide 1                                                         ___________________________________

                                                                ___________________________________

                                                                ___________________________________
                                 Sandy Wolff, MS, CHP, DABR
                                  Radiation Safety Officer,

                                                                ___________________________________
                                    Sentara Healthcare
                                        Norfolk, VA




                                                                ___________________________________

                                                                ___________________________________

                                                                ___________________________________

Slide 2                                                         ___________________________________
                  Objectives:
                                                                ___________________________________
          1. Understand the basic principles of radiation and
          how it can affect staff.

          2. Discuss the handling of radioactive material in
          the clinical and anatomic pathology laboratory
                                                                ___________________________________
          settings.

          3. Review laboratory procedures and processes
          related to radiation safety.                          ___________________________________

                                                                ___________________________________

                                                                ___________________________________

                                                                ___________________________________

Slide 3                                                         ___________________________________
              Polling Question
                                                                ___________________________________
             Do you use radioactive
             materials as part of a lab
             procedure to label specimens
             or perform other procedures?                       ___________________________________
              Yes
              No
              Not Sure                                         ___________________________________

                                                                ___________________________________

                                                                ___________________________________

                                                                ___________________________________
Slide 4                                                                  ___________________________________
          Regulatory Agencies
          ► NRC: Nuclear Regulatory Commission                           ___________________________________
            Jurisdiction
                       over all use of nuclear
            reactor byproduct material in USA

            Agreement
             38
                         State status
                 states have signed agreements with
                                                                         ___________________________________
              the NRC to regulate their own states’
              radioactive materials users

             Use     equivalent regulations to NRC
                                                                         ___________________________________

                                                                         ___________________________________

                                                                         ___________________________________

                                                                         ___________________________________

Slide 5                                                                  ___________________________________
             Regulatory Agencies
                       NRC   Agreement States – 38/50
                                                                         ___________________________________

                                                                         ___________________________________

                                                                         ___________________________________

                                                                         ___________________________________

                                                                         ___________________________________

                                                                         ___________________________________

Slide 6                                                                  ___________________________________
              State Regulatory
                  Agencies                                               ___________________________________
           Health or Environmental Division
             o Radiation Health Section or
             o Radiological Control Bureau
             o Regulates:                                                ___________________________________
                  o Ionizing x-ray equipment
                  o Linear accelerators
                  o Naturally occurring and cyclotron-produced


                                                                         ___________________________________
                    radioactive material
                  o Nuclear byproduct material also if agreement state




                                                                         ___________________________________

                                                                         ___________________________________

                                                                         ___________________________________
Slide 7                                                                            ___________________________________
                  Radioactivity Units
          1   millicurie (mCi) = 3.7 x 107 disintegration
              per second (dps) (clicks on the Geiger                               ___________________________________
              counter)


                                                                                   ___________________________________
           New     SI unit is becquerel (Bq) = 1
              disintegration per second (dps)
              o   ( 1 click on the Geiger counter)
                                                                                   ___________________________________

                                                                                   ___________________________________

                                                                                   ___________________________________

                                                                                   ___________________________________

Slide 8                                                                            ___________________________________
                     Radiation Units
          1      Roentgen = 1 rad = 1 rem                                         ___________________________________
                    (in most cases)
           New       SI units:
                 grays (Gy)
                 sieverts (Sv)                                                    ___________________________________
           Most   of us in the field still
              converse in rad and rem
          o   although the journals have moved to gray and
              sievert…                                                             ___________________________________

                                                                                   ___________________________________

                                                                                   ___________________________________

                                                                                   ___________________________________

Slide 9                                                                            ___________________________________
          Common Unsealed Radionuclides
          These isotopes are used in nuclear medicine and radiation oncology to
          diagnose and treat various conditions. Most are excreted in the urine.
                                                                                   ___________________________________

                                                                                   ___________________________________

                                                                                   ___________________________________

                                                                                   ___________________________________

                                                                                   ___________________________________

                                                                                   ___________________________________
Slide 10                                                                                ___________________________________
                   Common Sealed Sources
           These seeds are implanted in tissue and remain unless surgically
           removed – no blood or urine contamination.
                                                                                        ___________________________________

                                                                                        ___________________________________

                                                                                        ___________________________________
                * Aft er t en half lives, consider ed essent ially decayed t o zer o.




                                                                                        ___________________________________

                                                                                        ___________________________________

                                                                                        ___________________________________

Slide 11                                                                                ___________________________________
               Prostate Therapy Seed Implant

                                                                                        ___________________________________

                                                                                        ___________________________________

                                                                                        ___________________________________

                                                                                        ___________________________________

                                                                                        ___________________________________

                                                                                        ___________________________________

Slide 12                                                                                ___________________________________
                Breast Tissue Specimen With
                        Seed in Place
            New use of seeds to localize breast tumors                                 ___________________________________
              Low activity seed and only one or two are used




                                                                                        ___________________________________

                                                                                        ___________________________________

                                                                                        ___________________________________

                                                                                        ___________________________________

                                                                                        ___________________________________
Slide 13                                                            ___________________________________
            GM survey meter – used to survey for contamination



                                                                    ___________________________________

                                                                    ___________________________________

                                                                    ___________________________________

                                                                    ___________________________________

                                                                    ___________________________________

                                                                    ___________________________________

Slide 14                                                            ___________________________________
                          Acronyms
             ALARA     - As Low as Reasonably
                               Achievable                           ___________________________________
             RSC    - Radiation Safety Committee
               Review   occupational radiation exposure and
                  ALARA issues, Approve radiation safety policies
                  and procedures, investigate Medical Events.
                                                                    ___________________________________
             RSO    - Radiation Safety Officer
                  Legally responsible for ensuring compliance
                                                                    ___________________________________
              o
                  with federal and state radiation safety
                  regulations.




                                                                    ___________________________________

                                                                    ___________________________________

                                                                    ___________________________________

Slide 15                                                            ___________________________________
             Principles of Radiation
                 Protection (TDS)                                   ___________________________________
           Time:    Minimize Time


                                                                    ___________________________________
             Exposure is proportional to time
             Work quickly and efficiently
             Have all materials at hand prior to start
                                                                    ___________________________________

                                                                    ___________________________________

                                                                    ___________________________________

                                                                    ___________________________________
Slide 16                                                          ___________________________________
             Principles of Radiation
                 Protection (TDS)                                 ___________________________________
            Distance:Maximize distance
             Inverse Square Law
             Double your distance, quarter your dose
             Lean back                                           ___________________________________
             Step back
             Exposure drops off
               quickly with distance
                                                                  ___________________________________

                                                                  ___________________________________

                                                                  ___________________________________

                                                                  ___________________________________

Slide 17                                                          ___________________________________
             Principles of Radiation
                 Protection (TDS)                                 ___________________________________
            Shielding   - lead is the best for radiation
             Shielded   vials for transporting seeds and doses
             Lead   bricks in hot labs for storage of large
              amounts                                             ___________________________________
             Lead aprons not appropriate
               for isotope shielding


                                                                  ___________________________________

                                                                  ___________________________________

                                                                  ___________________________________

                                                                  ___________________________________

Slide 18                                                          ___________________________________
                Film and Ring Badges
               Film and ring badges                               ___________________________________

                                                                  ___________________________________

                                                                  ___________________________________

                                                                  ___________________________________

                                                                  ___________________________________

                                                                  ___________________________________
Slide 19                                                         ___________________________________
                Annual Occupational
                    Dose Limits
              Whole body - effective dose                       ___________________________________
                 50 mSv
                 (5000 mrem)
                 (5 rem)                                        ___________________________________
                      Monitoring required at 10%
                       of this limit
                      Most nuclear medicine staff
                       do not reach this level                   ___________________________________

                                                                 ___________________________________

                                                                 ___________________________________

                                                                 ___________________________________

Slide 20                                                         ___________________________________
                Annual Occupational
                    Dose Limits
                                                                 ___________________________________

                                                                 ___________________________________

                                                                 ___________________________________

                                                                 ___________________________________

                                                                 ___________________________________

                                                                 ___________________________________

Slide 21                                                         ___________________________________
                  Annual Dose Limits
                   General Public
           (those who are not trained and not monitored)
                                                                 ___________________________________
           1 mSv (100 mrem)

           • Our use of radioactive material may not result in
             any member of the general public being exposed
             to 100 millirem per year                            ___________________________________
           • Considered a negligible dose by regulatory
             bodies
           • Staff who are not radiation workers
           • Also must be considered and calculated when
             highly radioactive patients go home to their        ___________________________________
             families



                                                                 ___________________________________

                                                                 ___________________________________

                                                                 ___________________________________
Slide 22                                                              ___________________________________
                Declared Pregnancy
                     Dose Limit
                                                                      ___________________________________
           Unborn  child exposure
            5 mSv (500 mrem)
            (entire gestation)                                       ___________________________________

            0.5   mSv (50 mrem) per month
                                                                      ___________________________________

                                                                      ___________________________________

                                                                      ___________________________________

                                                                      ___________________________________

Slide 23                                                              ___________________________________
               Patient Handling
                                                                      ___________________________________
             Phlebotomy/Other         Procedures

               Patients who receive radioactive substances
                for treatment are not hazardous to healthcare         ___________________________________
                workers.

               Radiation may be present, but there are ways
                to protect yourself.                                  ___________________________________

                                                                      ___________________________________

                                                                      ___________________________________

                                                                      ___________________________________

Slide 24                                                              ___________________________________
               Patient Handling
                                                                      ___________________________________
             Utilize
                   Standard Precautions for all collection
              procedures.

             Follow  any instructions listed for the patient (i.e.   ___________________________________
              instructions posted in room)

             Limitduration of time in close contact with
              patient.
                                                                      ___________________________________

                                                                      ___________________________________

                                                                      ___________________________________

                                                                      ___________________________________
Slide 25                                                        ___________________________________
              Patient Handling
            Precautions  for radiation therapy patients are
            similar to those for patients isolated for other
            reasons
                                                                ___________________________________
            Use   PPE as instructed via postings.
               Foot covers, gowns, lab coats, gloves

            DiscardPPE into containers for radioactive waste   ___________________________________
            inside patient room or in ante-room.

            Perform hand hygiene before exiting room.
                                                                ___________________________________
            Pregnant staff should avoid caring for patient.



                                                                ___________________________________

                                                                ___________________________________

                                                                ___________________________________

Slide 26                                                        ___________________________________
                Polling Question
              Are you notified if/when you
                                                                ___________________________________
              are given radioactive
              specimens from other
              departments (blood/urine) ?
                                                                ___________________________________
               Yes

               No
                                                                ___________________________________
               Sometimes


                                                                ___________________________________

                                                                ___________________________________

                                                                ___________________________________

Slide 27                                                        ___________________________________
             Sample Handling
                                                                ___________________________________
            Have     not detected radiation from
                blood, urine or body fluids of most
                radiation patients.                             ___________________________________
            Do     not normally perform urine
                testing on I-131 patients, but it
                would be radioactive!                           ___________________________________

                                                                ___________________________________

                                                                ___________________________________

                                                                ___________________________________
Slide 28                                                           ___________________________________
           Sample Handling
                                                                   ___________________________________
            No special measures need to be taken for
            clinical specimen transport .

            BottomLine: Use Standard Precautions to               ___________________________________
            handle radioactive specimens unless
            otherwise directed.

            Questions?
            Officer.
                              Contact your Radiation Safety
                                                                   ___________________________________

                                                                   ___________________________________

                                                                   ___________________________________

                                                                   ___________________________________

Slide 29                                                           ___________________________________
            Sample Handling
                                                                   ___________________________________
            Process      blood and urine samples as usual.
                OK to run samples on lab analyzers.


            Becareful not to generate aerosols with
            radioactive specimens.
                                                                   ___________________________________
                  Allow centrifuges to come to a complete stop,
                  wait three minutes before opening.
                      Cap specimens for vortexing.
                                                                   ___________________________________
                  




                                                                   ___________________________________

                                                                   ___________________________________

                                                                   ___________________________________

Slide 30                                                           ___________________________________
            Sample Handling
                                                                   ___________________________________
            Other      handling safety tips:
              Prevent       punctures
                  Protect
                  Never
                            against glass breakage
                           recap needles                           ___________________________________
              Prevent       ingestion
                  No   food or drink in lab areas
              Prevent       absorption
                  Wear    gloves, lab coats, face protection      ___________________________________

                                                                   ___________________________________

                                                                   ___________________________________

                                                                   ___________________________________
Slide 31                                                                ___________________________________
             Polling Question
            Does your laboratory use
                                                                        ___________________________________
            radiation detectors?

             Yes
                                                                        ___________________________________
             No


                                                                        ___________________________________

                                                                        ___________________________________

                                                                        ___________________________________

                                                                        ___________________________________

Slide 32                                                                ___________________________________
            Sample Handling
                                                                        ___________________________________
            Disposal    of Clinical Specimens
                Blood and urine can be disposed of per routine
                 laboratory procedure. Treat these as usual regulated
                 medical waste.
                                                                        ___________________________________
                Some sites recommend disposing of known
                 radioactive samples immediately to minimize
                 exposure to staff.

                                                                        ___________________________________

                                                                        ___________________________________

                                                                        ___________________________________

                                                                        ___________________________________

Slide 33                                                                ___________________________________
            Sample Handling
                                                                        ___________________________________
            Disposal    of Pathology Specimens and Seeds

                 Contact the Radiation Safety Officer for specific
                                                                        ___________________________________
             
                 instructions.

                Contact Nuclear Medicine department for pick up if
                 that is an option.

                Store separately from other samples.
                                                                        ___________________________________

                                                                        ___________________________________

                                                                        ___________________________________

                                                                        ___________________________________
Slide 34                                                ___________________________________
                  Lab Procedures
                     Involving                          ___________________________________
                   Radioactivity
                                                        ___________________________________
                Prostate Seeds
                Sentinel Node Biopsy
                Radioactive Tissue Biopsy
                Breast Seeds
                                                        ___________________________________

                                                        ___________________________________

                                                        ___________________________________

                                                        ___________________________________

Slide 35                                                ___________________________________
                     Prostate Seeds
                                                        ___________________________________
                Usually permanently implanted I-125
                 seeds
                Seeds arrive in lab embedded in
                 prostate tissue
                                                        ___________________________________

                                                        ___________________________________

                                                        ___________________________________

                                                        ___________________________________

                                                        ___________________________________

Slide 36                                                ___________________________________
                     Prostate Seeds
                                                        ___________________________________
            Seeds   are removed using forceps

            Place seeds in tin foil, place foil into
             lead container
                                                        ___________________________________
            Contact
                   Radiation Safety Officer for
            removal/disposal process
                                                        ___________________________________

                                                        ___________________________________

                                                        ___________________________________

                                                        ___________________________________
Slide 37                                                       ___________________________________
                     Sentinel Node
                       Biopsies                                ___________________________________
               Sentinel   Node Lymph Biopsy

               Gamma      radiation
                                                               ___________________________________
                 No risk to transport personnel, processors
                 Minimal risk to pathologists
                 Use standard precautions to handle
                                                               ___________________________________

                                                               ___________________________________

                                                               ___________________________________

                                                               ___________________________________

Slide 38                                                       ___________________________________
                   Tissue Biopsies
                                                               ___________________________________
               Very
                   rare that known radioactive tissue
               would be removed for biopsy

               Removal of tissue after treatment with
                                                               ___________________________________
               radioactive iodine


                                                               ___________________________________

                                                               ___________________________________

                                                               ___________________________________

                                                               ___________________________________

Slide 39                                                       ___________________________________
                   Breast Implant
                       Seeds                                   ___________________________________
            New  procedure
            Seeds   are removed and counted
            Place into lead containers
            Check area for radioactivity                      ___________________________________
            Store if necessary
            Return for disposal

                                                               ___________________________________

                                                               ___________________________________

                                                               ___________________________________

                                                               ___________________________________
Slide 40                                                           ___________________________________
                     Lab Radiation
                        Safety                                     ___________________________________
                   CLSIGuidelines: GP-17 A3, Clinical
                    Laboratory Safety

                   Appendix     A: Radiation Safety               ___________________________________
                   Guidance for good practices as well as
                    meet NRC and state regulations

                                                                   ___________________________________

                                                                   ___________________________________

                                                                   ___________________________________

                                                                   ___________________________________

Slide 41                                                           ___________________________________
                                  CLSI
                     General      Radiation Safety                ___________________________________
                      Radioactive material must be secured from
                       unauthorized access

                      Radioactive waste                           ___________________________________
                      Radioactive samples
                      Radioactive reagents



                                                                   ___________________________________

                                                                   ___________________________________

                                                                   ___________________________________

                                                                   ___________________________________

Slide 42                                                           ___________________________________
                                  CLSI
           Signs
           
                      and Labels
               “Caution (or Danger), Radioactive Materials.”
                                                                   ___________________________________
              Refrigerators, other containers


           Radiation        Survey
              Wipe tests                                          ___________________________________
              Sealed sources


           Necessary           Equipment
                                                                   ___________________________________

                                                                   ___________________________________

                                                                   ___________________________________

                                                                   ___________________________________
Slide 43                                                 ___________________________________
                       CLSI
           Safe    Work Practices                       ___________________________________
             PPE


             Personnel   Monitoring                     ___________________________________

                                                         ___________________________________

                                                         ___________________________________

                                                         ___________________________________

                                                         ___________________________________

Slide 44                                                 ___________________________________
                       CLSI
           Radioactive     Material Spills              ___________________________________
            S = Secure the area, inform others
            P = Protect yourself (PPE)
            I = Inspect the Spill
            L = Lay down a barrier                       ___________________________________
            L = Lay down absorbents
            E = Extract the mess
            D = Dispose of waste properly
                                                         ___________________________________

                                                         ___________________________________

                                                         ___________________________________

                                                         ___________________________________

Slide 45                                                 ___________________________________
                       CLSI
           Extra   precautions                          ___________________________________
             Wipe   inward toward center of spill to
              localize contamination
             Use a disinfectant if a biological agent
              is involved
             Remove gloves, shoes and lab coats
                                                         ___________________________________
              before leaving the area, treat as
              radioactive waste
             If skin is contaminated, wash as soon
              as possible                                ___________________________________

                                                         ___________________________________

                                                         ___________________________________

                                                         ___________________________________
Slide 46                                                                  ___________________________________
                                    CLSI
                   Basic     Rules                                       ___________________________________
                     Do not mix radioactive and non-
                      radioactive waste
                     Package dry and liquid waste
                      separately and by isotope
                     Never keep waste in public or
                                                                          ___________________________________
                      unsecured areas
                     Get permission from RSO for sink
                      disposal
                     Ensure disinfectants do not liberate
                                                                          ___________________________________
                      volatile radionuclides


                                                                          ___________________________________

                                                                          ___________________________________

                                                                          ___________________________________

Slide 47                                                                  ___________________________________
                                    CAP
            Gen.20374:     The laboratory has a policy for
               ensuring compliance with applicable state and
                                                                          ___________________________________
               local laws and regulations.


                                                                          ___________________________________
              The note states that this includes “handling radioactive
               materials.”




                                                                          ___________________________________

                                                                          ___________________________________

                                                                          ___________________________________

                                                                          ___________________________________

Slide 48                                                                  ___________________________________
                                    CAP
                                                                          ___________________________________
                   Gen.54400:   Personnel files include
                     records of radiation exposure where
                     applicable.
                                                                          ___________________________________

                                                                          ___________________________________

                                                                          ___________________________________

                                                                          ___________________________________

                                                                          ___________________________________
Slide 49                                                         ___________________________________
                                CAP
                                                                 ___________________________________
                 Gen.60150:   There is adequate space
                   for radionuclide storage, as
                   applicable.
                                                                 ___________________________________

                                                                 ___________________________________

                                                                 ___________________________________

                                                                 ___________________________________

                                                                 ___________________________________

Slide 50                                                         ___________________________________
                                CAP
                                                                 ___________________________________
                 Gen.77000:   Policies and procedures
                   are documented and adequate for
                   radiation safety.
                                                                 ___________________________________

                                                                 ___________________________________

                                                                 ___________________________________

                                                                 ___________________________________

                                                                 ___________________________________

Slide 51                                                         ___________________________________
                                CAP
                                                                 ___________________________________
            Gen.77100: There are specific policies and
            procedures for the safe handling of tissues that
            may contain radioactive material (e.g. sentinel
            lymph nodes, breast biopsies, prostate "seeds",
            etc.).                                               ___________________________________
               ANP.11275 for those labs that perform anatomic
                pathology on site.


                                                                 ___________________________________

                                                                 ___________________________________

                                                                 ___________________________________

                                                                 ___________________________________
Slide 52                                                          ___________________________________
                              CAP
            Gen.77100                                            ___________________________________
            NOTE: These procedures should be developed in
            conjunction with the institutional radiation safety
            officer, and must comply with any state
            regulations for the safe handling of tissues          ___________________________________
            containing radionuclides. The policy should
            distinguish between low radioactivity specimens
            such as sentinel lymphadenectomy and implant
            devices with higher radiation levels.
                                                                  ___________________________________

                                                                  ___________________________________

                                                                  ___________________________________

                                                                  ___________________________________

Slide 53                                                          ___________________________________
                              CAP
                ANP.
                The
                       11275
                      note states: The pathology
                                                                  ___________________________________
                 department may wish to monitor
                 (potentially radioactive) specimens
                 for radioactivity, with safe storage of
                 specimens until sufficient decaying
                                                                  ___________________________________
                 has occurred, before proceeding with
                 processing in the
                 histology laboratory.
                                                                  ___________________________________

                                                                  ___________________________________

                                                                  ___________________________________

                                                                  ___________________________________

Slide 54                                                          ___________________________________
                Polling Question
               Do you have radiation safety
                                                                  ___________________________________
               policies or procedures in your
               laboratory?

                Yes
                                                                  ___________________________________
                No

                                                                  ___________________________________

                                                                  ___________________________________

                                                                  ___________________________________

                                                                  ___________________________________
Slide 55                                                                       ___________________________________
                 Lab Procedures
              Handling of Prostate Seeds:                                     ___________________________________
            Utilize Standard Precautions for all specimens
            Obtain lead container
            Use forceps to pick up seed(s) and wrap seeds in aluminum
            foil
            Place foil-wrapped seed in lead container and replace cap          ___________________________________
            Disinfect forceps with a 10% bleach solution.
            Page Radiation Safety Officer
            Turn lead container over to nuclear medicine staff


                                                                               ___________________________________

                                                                               ___________________________________

                                                                               ___________________________________

                                                                               ___________________________________

Slide 56                                                                       ___________________________________
                 Lab Procedures
                                                                               ___________________________________
              Handling      Specimens From Known Radioactive
                Patients:

                                                                               ___________________________________
            Utilize Standard Precautions for all specimens
            Minimize time spent working with known radioactive samples
            Maximize distance from known radioactive samples
            Run samples on instruments as usual
            Page Radiation Safety Officer for instructions prior to disposal


                                                                               ___________________________________

                                                                               ___________________________________

                                                                               ___________________________________

                                                                               ___________________________________

Slide 57                                                                       ___________________________________
                 Lab Procedures
                                                                               ___________________________________
              Isolation       of Radioactive Breast Seeds:
           Use scintillation meter as needed to locate seed in specimen.
           Remove seed from tissue.
           Place seed in glass vial inside lead container .
                                                                               ___________________________________
           Note date and number of seeds on rad sticker.
           Survey work area AND specimen with meter to ensure no
           contamination remains.
                                                                               ___________________________________

                                                                               ___________________________________

                                                                               ___________________________________

                                                                               ___________________________________
Slide 58                                                                                    ___________________________________
                     Lab Procedures
                                                                                            ___________________________________
                   Isolation     of Radioactive Breast Seeds:
                  Note: If seed compromise (lost seed, cutting of seed) occurs in
                            the laboratory, complete the following steps:


                Obtain lead container to collect seed.                                      ___________________________________
                Locate and contain actual seed using Scintillation detector if
                necessary.
                Place seed inside lead container.


                                                                                            ___________________________________
                Survey area of suspected contamination.
                Contact Radiation Safety Officer for further guidance.
                Complete proper reports.




                                                                                            ___________________________________

                                                                                            ___________________________________

                                                                                            ___________________________________

Slide 59                                                                                    ___________________________________
                     Lab Procedures
                                                                                            ___________________________________
                   Isolation     of Radioactive Breast Seeds:

                      Example Radiation Survey Log:

                                 Background      Tissue       Area
                                                             Reading # seeds
                                                                                Pathology   ___________________________________
           Date Time Case MRN      Reading      Reading                          Initials
                      #           counts/sec   counts/sec   counts/sec isolated




                                                                                            ___________________________________

                                                                                            ___________________________________

                                                                                            ___________________________________

                                                                                            ___________________________________

Slide 60                                                                                    ___________________________________
                     Lab Procedures
                                                                                            ___________________________________
                   Remember:
                   Radiation  precautions are the same as
                    for other laboratory Standard
                    Precautions                                                             ___________________________________
                   Radioactive in-patients are treated as
                    other isolation patients
                   Time, distance, and shielding are the 3
                    special tools used for radiation safety                                 ___________________________________

                                                                                            ___________________________________

                                                                                            ___________________________________

                                                                                            ___________________________________
Slide 61                                              ___________________________________
           Now It’s Your Turn to Ask
                 The Experts
                                                      ___________________________________
                      Sandy Wolff, MS, CHP, DABR
                        Radiation Safety Officer,
                          Sentara Healthcare
                              Norfolk, VA

                                                      ___________________________________
                          Thank you!
               For more information, contact me at:
                       samaritan@cox,net
               Facebook.com/danthelabsafetyman        ___________________________________

                                                      ___________________________________

                                                      ___________________________________

                                                      ___________________________________

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February 2013 academy radiation safety handouts

  • 1. Slide 1 ___________________________________ ___________________________________ ___________________________________ Sandy Wolff, MS, CHP, DABR Radiation Safety Officer, ___________________________________ Sentara Healthcare Norfolk, VA ___________________________________ ___________________________________ ___________________________________ Slide 2 ___________________________________ Objectives: ___________________________________ 1. Understand the basic principles of radiation and how it can affect staff. 2. Discuss the handling of radioactive material in the clinical and anatomic pathology laboratory ___________________________________ settings. 3. Review laboratory procedures and processes related to radiation safety. ___________________________________ ___________________________________ ___________________________________ ___________________________________ Slide 3 ___________________________________ Polling Question ___________________________________ Do you use radioactive materials as part of a lab procedure to label specimens or perform other procedures? ___________________________________  Yes  No  Not Sure ___________________________________ ___________________________________ ___________________________________ ___________________________________
  • 2. Slide 4 ___________________________________ Regulatory Agencies ► NRC: Nuclear Regulatory Commission ___________________________________  Jurisdiction over all use of nuclear reactor byproduct material in USA  Agreement 38 State status states have signed agreements with ___________________________________ the NRC to regulate their own states’ radioactive materials users Use equivalent regulations to NRC ___________________________________ ___________________________________ ___________________________________ ___________________________________ Slide 5 ___________________________________ Regulatory Agencies  NRC Agreement States – 38/50 ___________________________________ ___________________________________ ___________________________________ ___________________________________ ___________________________________ ___________________________________ Slide 6 ___________________________________ State Regulatory Agencies ___________________________________  Health or Environmental Division o Radiation Health Section or o Radiological Control Bureau o Regulates: ___________________________________ o Ionizing x-ray equipment o Linear accelerators o Naturally occurring and cyclotron-produced ___________________________________ radioactive material o Nuclear byproduct material also if agreement state ___________________________________ ___________________________________ ___________________________________
  • 3. Slide 7 ___________________________________ Radioactivity Units 1 millicurie (mCi) = 3.7 x 107 disintegration per second (dps) (clicks on the Geiger ___________________________________ counter) ___________________________________  New SI unit is becquerel (Bq) = 1 disintegration per second (dps) o ( 1 click on the Geiger counter) ___________________________________ ___________________________________ ___________________________________ ___________________________________ Slide 8 ___________________________________ Radiation Units 1 Roentgen = 1 rad = 1 rem ___________________________________ (in most cases)  New SI units:  grays (Gy)  sieverts (Sv) ___________________________________  Most of us in the field still converse in rad and rem o although the journals have moved to gray and sievert… ___________________________________ ___________________________________ ___________________________________ ___________________________________ Slide 9 ___________________________________ Common Unsealed Radionuclides These isotopes are used in nuclear medicine and radiation oncology to diagnose and treat various conditions. Most are excreted in the urine. ___________________________________ ___________________________________ ___________________________________ ___________________________________ ___________________________________ ___________________________________
  • 4. Slide 10 ___________________________________ Common Sealed Sources These seeds are implanted in tissue and remain unless surgically removed – no blood or urine contamination. ___________________________________ ___________________________________ ___________________________________ * Aft er t en half lives, consider ed essent ially decayed t o zer o. ___________________________________ ___________________________________ ___________________________________ Slide 11 ___________________________________ Prostate Therapy Seed Implant ___________________________________ ___________________________________ ___________________________________ ___________________________________ ___________________________________ ___________________________________ Slide 12 ___________________________________ Breast Tissue Specimen With Seed in Place  New use of seeds to localize breast tumors ___________________________________  Low activity seed and only one or two are used ___________________________________ ___________________________________ ___________________________________ ___________________________________ ___________________________________
  • 5. Slide 13 ___________________________________ GM survey meter – used to survey for contamination ___________________________________ ___________________________________ ___________________________________ ___________________________________ ___________________________________ ___________________________________ Slide 14 ___________________________________ Acronyms  ALARA - As Low as Reasonably Achievable ___________________________________  RSC - Radiation Safety Committee  Review occupational radiation exposure and ALARA issues, Approve radiation safety policies and procedures, investigate Medical Events. ___________________________________  RSO - Radiation Safety Officer Legally responsible for ensuring compliance ___________________________________ o with federal and state radiation safety regulations. ___________________________________ ___________________________________ ___________________________________ Slide 15 ___________________________________ Principles of Radiation Protection (TDS) ___________________________________ Time: Minimize Time ___________________________________  Exposure is proportional to time  Work quickly and efficiently  Have all materials at hand prior to start ___________________________________ ___________________________________ ___________________________________ ___________________________________
  • 6. Slide 16 ___________________________________ Principles of Radiation Protection (TDS) ___________________________________  Distance:Maximize distance  Inverse Square Law  Double your distance, quarter your dose  Lean back ___________________________________  Step back  Exposure drops off quickly with distance ___________________________________ ___________________________________ ___________________________________ ___________________________________ Slide 17 ___________________________________ Principles of Radiation Protection (TDS) ___________________________________  Shielding - lead is the best for radiation  Shielded vials for transporting seeds and doses  Lead bricks in hot labs for storage of large amounts ___________________________________  Lead aprons not appropriate for isotope shielding ___________________________________ ___________________________________ ___________________________________ ___________________________________ Slide 18 ___________________________________ Film and Ring Badges Film and ring badges ___________________________________ ___________________________________ ___________________________________ ___________________________________ ___________________________________ ___________________________________
  • 7. Slide 19 ___________________________________ Annual Occupational Dose Limits  Whole body - effective dose ___________________________________  50 mSv  (5000 mrem)  (5 rem) ___________________________________  Monitoring required at 10% of this limit  Most nuclear medicine staff do not reach this level ___________________________________ ___________________________________ ___________________________________ ___________________________________ Slide 20 ___________________________________ Annual Occupational Dose Limits ___________________________________ ___________________________________ ___________________________________ ___________________________________ ___________________________________ ___________________________________ Slide 21 ___________________________________ Annual Dose Limits General Public (those who are not trained and not monitored) ___________________________________ 1 mSv (100 mrem) • Our use of radioactive material may not result in any member of the general public being exposed to 100 millirem per year ___________________________________ • Considered a negligible dose by regulatory bodies • Staff who are not radiation workers • Also must be considered and calculated when highly radioactive patients go home to their ___________________________________ families ___________________________________ ___________________________________ ___________________________________
  • 8. Slide 22 ___________________________________ Declared Pregnancy Dose Limit ___________________________________ Unborn child exposure 5 mSv (500 mrem) (entire gestation) ___________________________________ 0.5 mSv (50 mrem) per month ___________________________________ ___________________________________ ___________________________________ ___________________________________ Slide 23 ___________________________________ Patient Handling ___________________________________  Phlebotomy/Other Procedures  Patients who receive radioactive substances for treatment are not hazardous to healthcare ___________________________________ workers.  Radiation may be present, but there are ways to protect yourself. ___________________________________ ___________________________________ ___________________________________ ___________________________________ Slide 24 ___________________________________ Patient Handling ___________________________________  Utilize Standard Precautions for all collection procedures.  Follow any instructions listed for the patient (i.e. ___________________________________ instructions posted in room)  Limitduration of time in close contact with patient. ___________________________________ ___________________________________ ___________________________________ ___________________________________
  • 9. Slide 25 ___________________________________ Patient Handling  Precautions for radiation therapy patients are similar to those for patients isolated for other reasons ___________________________________  Use PPE as instructed via postings.  Foot covers, gowns, lab coats, gloves  DiscardPPE into containers for radioactive waste ___________________________________ inside patient room or in ante-room. Perform hand hygiene before exiting room. ___________________________________ Pregnant staff should avoid caring for patient. ___________________________________ ___________________________________ ___________________________________ Slide 26 ___________________________________ Polling Question Are you notified if/when you ___________________________________ are given radioactive specimens from other departments (blood/urine) ? ___________________________________  Yes  No ___________________________________  Sometimes ___________________________________ ___________________________________ ___________________________________ Slide 27 ___________________________________ Sample Handling ___________________________________ Have not detected radiation from blood, urine or body fluids of most radiation patients. ___________________________________ Do not normally perform urine testing on I-131 patients, but it would be radioactive! ___________________________________ ___________________________________ ___________________________________ ___________________________________
  • 10. Slide 28 ___________________________________ Sample Handling ___________________________________  No special measures need to be taken for clinical specimen transport .  BottomLine: Use Standard Precautions to ___________________________________ handle radioactive specimens unless otherwise directed.  Questions? Officer. Contact your Radiation Safety ___________________________________ ___________________________________ ___________________________________ ___________________________________ Slide 29 ___________________________________ Sample Handling ___________________________________  Process blood and urine samples as usual.  OK to run samples on lab analyzers.  Becareful not to generate aerosols with radioactive specimens. ___________________________________  Allow centrifuges to come to a complete stop, wait three minutes before opening. Cap specimens for vortexing. ___________________________________  ___________________________________ ___________________________________ ___________________________________ Slide 30 ___________________________________ Sample Handling ___________________________________  Other handling safety tips:  Prevent punctures  Protect  Never against glass breakage recap needles ___________________________________  Prevent ingestion  No food or drink in lab areas  Prevent absorption  Wear gloves, lab coats, face protection ___________________________________ ___________________________________ ___________________________________ ___________________________________
  • 11. Slide 31 ___________________________________ Polling Question Does your laboratory use ___________________________________ radiation detectors?  Yes ___________________________________  No ___________________________________ ___________________________________ ___________________________________ ___________________________________ Slide 32 ___________________________________ Sample Handling ___________________________________  Disposal of Clinical Specimens  Blood and urine can be disposed of per routine laboratory procedure. Treat these as usual regulated medical waste. ___________________________________  Some sites recommend disposing of known radioactive samples immediately to minimize exposure to staff. ___________________________________ ___________________________________ ___________________________________ ___________________________________ Slide 33 ___________________________________ Sample Handling ___________________________________  Disposal of Pathology Specimens and Seeds Contact the Radiation Safety Officer for specific ___________________________________  instructions.  Contact Nuclear Medicine department for pick up if that is an option.  Store separately from other samples. ___________________________________ ___________________________________ ___________________________________ ___________________________________
  • 12. Slide 34 ___________________________________ Lab Procedures Involving ___________________________________ Radioactivity ___________________________________  Prostate Seeds  Sentinel Node Biopsy  Radioactive Tissue Biopsy  Breast Seeds ___________________________________ ___________________________________ ___________________________________ ___________________________________ Slide 35 ___________________________________ Prostate Seeds ___________________________________  Usually permanently implanted I-125 seeds  Seeds arrive in lab embedded in prostate tissue ___________________________________ ___________________________________ ___________________________________ ___________________________________ ___________________________________ Slide 36 ___________________________________ Prostate Seeds ___________________________________  Seeds are removed using forceps  Place seeds in tin foil, place foil into lead container ___________________________________  Contact Radiation Safety Officer for removal/disposal process ___________________________________ ___________________________________ ___________________________________ ___________________________________
  • 13. Slide 37 ___________________________________ Sentinel Node Biopsies ___________________________________  Sentinel Node Lymph Biopsy  Gamma radiation ___________________________________  No risk to transport personnel, processors  Minimal risk to pathologists  Use standard precautions to handle ___________________________________ ___________________________________ ___________________________________ ___________________________________ Slide 38 ___________________________________ Tissue Biopsies ___________________________________  Very rare that known radioactive tissue would be removed for biopsy  Removal of tissue after treatment with ___________________________________ radioactive iodine ___________________________________ ___________________________________ ___________________________________ ___________________________________ Slide 39 ___________________________________ Breast Implant Seeds ___________________________________  New procedure  Seeds are removed and counted  Place into lead containers  Check area for radioactivity ___________________________________  Store if necessary  Return for disposal ___________________________________ ___________________________________ ___________________________________ ___________________________________
  • 14. Slide 40 ___________________________________ Lab Radiation Safety ___________________________________  CLSIGuidelines: GP-17 A3, Clinical Laboratory Safety  Appendix A: Radiation Safety ___________________________________  Guidance for good practices as well as meet NRC and state regulations ___________________________________ ___________________________________ ___________________________________ ___________________________________ Slide 41 ___________________________________ CLSI General Radiation Safety ___________________________________  Radioactive material must be secured from unauthorized access  Radioactive waste ___________________________________  Radioactive samples  Radioactive reagents ___________________________________ ___________________________________ ___________________________________ ___________________________________ Slide 42 ___________________________________ CLSI Signs  and Labels “Caution (or Danger), Radioactive Materials.” ___________________________________  Refrigerators, other containers Radiation Survey  Wipe tests ___________________________________  Sealed sources Necessary Equipment ___________________________________ ___________________________________ ___________________________________ ___________________________________
  • 15. Slide 43 ___________________________________ CLSI Safe Work Practices ___________________________________  PPE  Personnel Monitoring ___________________________________ ___________________________________ ___________________________________ ___________________________________ ___________________________________ Slide 44 ___________________________________ CLSI Radioactive Material Spills ___________________________________ S = Secure the area, inform others P = Protect yourself (PPE) I = Inspect the Spill L = Lay down a barrier ___________________________________ L = Lay down absorbents E = Extract the mess D = Dispose of waste properly ___________________________________ ___________________________________ ___________________________________ ___________________________________ Slide 45 ___________________________________ CLSI Extra precautions ___________________________________  Wipe inward toward center of spill to localize contamination  Use a disinfectant if a biological agent is involved  Remove gloves, shoes and lab coats ___________________________________ before leaving the area, treat as radioactive waste  If skin is contaminated, wash as soon as possible ___________________________________ ___________________________________ ___________________________________ ___________________________________
  • 16. Slide 46 ___________________________________ CLSI Basic Rules ___________________________________ Do not mix radioactive and non- radioactive waste Package dry and liquid waste separately and by isotope Never keep waste in public or ___________________________________ unsecured areas Get permission from RSO for sink disposal Ensure disinfectants do not liberate ___________________________________ volatile radionuclides ___________________________________ ___________________________________ ___________________________________ Slide 47 ___________________________________ CAP  Gen.20374: The laboratory has a policy for ensuring compliance with applicable state and ___________________________________ local laws and regulations. ___________________________________  The note states that this includes “handling radioactive materials.” ___________________________________ ___________________________________ ___________________________________ ___________________________________ Slide 48 ___________________________________ CAP ___________________________________ Gen.54400: Personnel files include records of radiation exposure where applicable. ___________________________________ ___________________________________ ___________________________________ ___________________________________ ___________________________________
  • 17. Slide 49 ___________________________________ CAP ___________________________________ Gen.60150: There is adequate space for radionuclide storage, as applicable. ___________________________________ ___________________________________ ___________________________________ ___________________________________ ___________________________________ Slide 50 ___________________________________ CAP ___________________________________ Gen.77000: Policies and procedures are documented and adequate for radiation safety. ___________________________________ ___________________________________ ___________________________________ ___________________________________ ___________________________________ Slide 51 ___________________________________ CAP ___________________________________  Gen.77100: There are specific policies and procedures for the safe handling of tissues that may contain radioactive material (e.g. sentinel lymph nodes, breast biopsies, prostate "seeds", etc.). ___________________________________  ANP.11275 for those labs that perform anatomic pathology on site. ___________________________________ ___________________________________ ___________________________________ ___________________________________
  • 18. Slide 52 ___________________________________ CAP  Gen.77100 ___________________________________  NOTE: These procedures should be developed in conjunction with the institutional radiation safety officer, and must comply with any state regulations for the safe handling of tissues ___________________________________ containing radionuclides. The policy should distinguish between low radioactivity specimens such as sentinel lymphadenectomy and implant devices with higher radiation levels. ___________________________________ ___________________________________ ___________________________________ ___________________________________ Slide 53 ___________________________________ CAP ANP. The 11275 note states: The pathology ___________________________________ department may wish to monitor (potentially radioactive) specimens for radioactivity, with safe storage of specimens until sufficient decaying ___________________________________ has occurred, before proceeding with processing in the histology laboratory. ___________________________________ ___________________________________ ___________________________________ ___________________________________ Slide 54 ___________________________________ Polling Question Do you have radiation safety ___________________________________ policies or procedures in your laboratory?  Yes ___________________________________  No ___________________________________ ___________________________________ ___________________________________ ___________________________________
  • 19. Slide 55 ___________________________________ Lab Procedures  Handling of Prostate Seeds: ___________________________________ Utilize Standard Precautions for all specimens Obtain lead container Use forceps to pick up seed(s) and wrap seeds in aluminum foil Place foil-wrapped seed in lead container and replace cap ___________________________________ Disinfect forceps with a 10% bleach solution. Page Radiation Safety Officer Turn lead container over to nuclear medicine staff ___________________________________ ___________________________________ ___________________________________ ___________________________________ Slide 56 ___________________________________ Lab Procedures ___________________________________  Handling Specimens From Known Radioactive Patients: ___________________________________ Utilize Standard Precautions for all specimens Minimize time spent working with known radioactive samples Maximize distance from known radioactive samples Run samples on instruments as usual Page Radiation Safety Officer for instructions prior to disposal ___________________________________ ___________________________________ ___________________________________ ___________________________________ Slide 57 ___________________________________ Lab Procedures ___________________________________  Isolation of Radioactive Breast Seeds: Use scintillation meter as needed to locate seed in specimen. Remove seed from tissue. Place seed in glass vial inside lead container . ___________________________________ Note date and number of seeds on rad sticker. Survey work area AND specimen with meter to ensure no contamination remains. ___________________________________ ___________________________________ ___________________________________ ___________________________________
  • 20. Slide 58 ___________________________________ Lab Procedures ___________________________________  Isolation of Radioactive Breast Seeds: Note: If seed compromise (lost seed, cutting of seed) occurs in the laboratory, complete the following steps: Obtain lead container to collect seed. ___________________________________ Locate and contain actual seed using Scintillation detector if necessary. Place seed inside lead container. ___________________________________ Survey area of suspected contamination. Contact Radiation Safety Officer for further guidance. Complete proper reports. ___________________________________ ___________________________________ ___________________________________ Slide 59 ___________________________________ Lab Procedures ___________________________________  Isolation of Radioactive Breast Seeds: Example Radiation Survey Log: Background Tissue Area Reading # seeds Pathology ___________________________________ Date Time Case MRN Reading Reading Initials # counts/sec counts/sec counts/sec isolated ___________________________________ ___________________________________ ___________________________________ ___________________________________ Slide 60 ___________________________________ Lab Procedures ___________________________________  Remember:  Radiation precautions are the same as for other laboratory Standard Precautions ___________________________________  Radioactive in-patients are treated as other isolation patients  Time, distance, and shielding are the 3 special tools used for radiation safety ___________________________________ ___________________________________ ___________________________________ ___________________________________
  • 21. Slide 61 ___________________________________ Now It’s Your Turn to Ask The Experts ___________________________________ Sandy Wolff, MS, CHP, DABR Radiation Safety Officer, Sentara Healthcare Norfolk, VA ___________________________________ Thank you! For more information, contact me at: samaritan@cox,net Facebook.com/danthelabsafetyman ___________________________________ ___________________________________ ___________________________________ ___________________________________