4. Introduction
A technique to suppress signal from normal adipose tissue
Typically inserted at the beginning of a normal sequence
Mousavi. M.Sc graduated in medical physics
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5. Indication
To reduce chemical shift artifact or improve
visualization
To improve tissue characterization
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Mousavi. M.Sc graduated in medical physics
6. Physics for fat suppression
Protons are saturated selectively
It requires homogeneity
Fat is different in terms of frequencies and relaxation
time
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Mousavi. M.Sc graduated in medical physics
7. Pros. & Cons.
Advantage
Contrast-enhanced T1w
imaging
Tissue characterization
Avoiding artifacts
Small details visualization
Disadvantage
Inhomogeneity of magnetic field
Inhomogeneity of frequency field
Inhomogeneity in tissue volume
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Mousavi. M.Sc graduated in medical physics
9. STIR (short time inversion recovery)
An IR pulse sequence with specific timing
Works in magnetic field inhomogeneities
Can be used with low magnetic field
strength
Long acquisition time and reduced SNR
Can not be used post Gd
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Mousavi. M.Sc graduated in medical physics
10. STIR (cont.)
Fluid appear bright and fat appear very
dark
Pathological process are usually bright
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Mousavi. M.Sc graduated in medical physics
11. CHESS (chemical shift selective)
Based on the chemical shift between fat & water
RF pulses tuned to the resonance frequency of fat
Fat protons were dephased
Can be used for post contrast imaging
Can not be used at low field strength or in inhomogeneity 11
Mousavi. M.Sc graduated in medical physics
12. Water Excitation
Based on chemical shift
Short series of RF pulses were used
Reduced sensitivity to inhomogeneous
field
Longer time and lower slice numbers
Used in musculoskeletal system
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Mousavi. M.Sc graduated in medical physics
13. DIXON-based
Based on chemical shift
Uses “in phase” & “out phase” cycling
“water only” & “fat only” images can be extracted
Insensitive to magnetic field inhomogeneties
Widely used in abdominal imaging
Useful for detection of small amount of fat
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Mousavi. M.Sc graduated in medical physics
14. SPIR (spectral pre saturation with inversion recovery)
A combination of STIR &
spectral saturation
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Mousavi. M.Sc graduated in medical physics
15. SPAIR (spectral attenuated inversion recovery)
A combination of STIR & CHESS
Uses adiabatic pulses
Tissue contrast is not affected
Longer inversion time
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Mousavi. M.Sc graduated in medical physics
Figure 1 Coronal PD-W TSE (left) and fat suppressed PD-W TSE (right) MR images of the right knee. Fat suppressed PD-W image can visualize the bone marrow edema on the medial condyle of femur and tibia, while no lesion is highlighted on the PD-W image. Image dataset acquired at 1.5 Tesla.