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In the name
of God
Fat Suppression in
MR Imaging
By S.Shokoofeh Mousavi
 Introduction
 Indication
 Physics for fat suppression
 Methods • STIR
• CHESS
• SPIR
• SPAIR
• Water Excitation
• DIXON-based
Introduction
 A technique to suppress signal from normal adipose tissue
 Typically inserted at the beginning of a normal sequence
Mousavi. M.Sc graduated in medical physics
4
Indication
 To reduce chemical shift artifact or improve
visualization
 To improve tissue characterization
5
Mousavi. M.Sc graduated in medical physics
Physics for fat suppression
 Protons are saturated selectively
 It requires homogeneity
 Fat is different in terms of frequencies and relaxation
time
6
Mousavi. M.Sc graduated in medical physics
Pros. & Cons.
Advantage
Contrast-enhanced T1w
imaging
Tissue characterization
Avoiding artifacts
Small details visualization
Disadvantage
Inhomogeneity of magnetic field
Inhomogeneity of frequency field
Inhomogeneity in tissue volume
7
Mousavi. M.Sc graduated in medical physics
Fat Suppression Methods
8
Mousavi. M.Sc graduated in medical physics
STIR (short time inversion recovery)
 An IR pulse sequence with specific timing
 Works in magnetic field inhomogeneities
 Can be used with low magnetic field
strength
 Long acquisition time and reduced SNR
 Can not be used post Gd
9
Mousavi. M.Sc graduated in medical physics
STIR (cont.)
 Fluid appear bright and fat appear very
dark
 Pathological process are usually bright
10
Mousavi. M.Sc graduated in medical physics
CHESS (chemical shift selective)
 Based on the chemical shift between fat & water
 RF pulses tuned to the resonance frequency of fat
 Fat protons were dephased
 Can be used for post contrast imaging
 Can not be used at low field strength or in inhomogeneity 11
Mousavi. M.Sc graduated in medical physics
Water Excitation
 Based on chemical shift
 Short series of RF pulses were used
 Reduced sensitivity to inhomogeneous
field
 Longer time and lower slice numbers
 Used in musculoskeletal system
12
Mousavi. M.Sc graduated in medical physics
DIXON-based
 Based on chemical shift
 Uses “in phase” & “out phase” cycling
 “water only” & “fat only” images can be extracted
 Insensitive to magnetic field inhomogeneties
 Widely used in abdominal imaging
 Useful for detection of small amount of fat
13
Mousavi. M.Sc graduated in medical physics
SPIR (spectral pre saturation with inversion recovery)
 A combination of STIR &
spectral saturation
14
Mousavi. M.Sc graduated in medical physics
SPAIR (spectral attenuated inversion recovery)
 A combination of STIR & CHESS
 Uses adiabatic pulses
 Tissue contrast is not affected
 Longer inversion time
15
Mousavi. M.Sc graduated in medical physics
Thanks for

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fat suppression in MRI

  • 2. Fat Suppression in MR Imaging By S.Shokoofeh Mousavi
  • 3.  Introduction  Indication  Physics for fat suppression  Methods • STIR • CHESS • SPIR • SPAIR • Water Excitation • DIXON-based
  • 4. Introduction  A technique to suppress signal from normal adipose tissue  Typically inserted at the beginning of a normal sequence Mousavi. M.Sc graduated in medical physics 4
  • 5. Indication  To reduce chemical shift artifact or improve visualization  To improve tissue characterization 5 Mousavi. M.Sc graduated in medical physics
  • 6. Physics for fat suppression  Protons are saturated selectively  It requires homogeneity  Fat is different in terms of frequencies and relaxation time 6 Mousavi. M.Sc graduated in medical physics
  • 7. Pros. & Cons. Advantage Contrast-enhanced T1w imaging Tissue characterization Avoiding artifacts Small details visualization Disadvantage Inhomogeneity of magnetic field Inhomogeneity of frequency field Inhomogeneity in tissue volume 7 Mousavi. M.Sc graduated in medical physics
  • 8. Fat Suppression Methods 8 Mousavi. M.Sc graduated in medical physics
  • 9. STIR (short time inversion recovery)  An IR pulse sequence with specific timing  Works in magnetic field inhomogeneities  Can be used with low magnetic field strength  Long acquisition time and reduced SNR  Can not be used post Gd 9 Mousavi. M.Sc graduated in medical physics
  • 10. STIR (cont.)  Fluid appear bright and fat appear very dark  Pathological process are usually bright 10 Mousavi. M.Sc graduated in medical physics
  • 11. CHESS (chemical shift selective)  Based on the chemical shift between fat & water  RF pulses tuned to the resonance frequency of fat  Fat protons were dephased  Can be used for post contrast imaging  Can not be used at low field strength or in inhomogeneity 11 Mousavi. M.Sc graduated in medical physics
  • 12. Water Excitation  Based on chemical shift  Short series of RF pulses were used  Reduced sensitivity to inhomogeneous field  Longer time and lower slice numbers  Used in musculoskeletal system 12 Mousavi. M.Sc graduated in medical physics
  • 13. DIXON-based  Based on chemical shift  Uses “in phase” & “out phase” cycling  “water only” & “fat only” images can be extracted  Insensitive to magnetic field inhomogeneties  Widely used in abdominal imaging  Useful for detection of small amount of fat 13 Mousavi. M.Sc graduated in medical physics
  • 14. SPIR (spectral pre saturation with inversion recovery)  A combination of STIR & spectral saturation 14 Mousavi. M.Sc graduated in medical physics
  • 15. SPAIR (spectral attenuated inversion recovery)  A combination of STIR & CHESS  Uses adiabatic pulses  Tissue contrast is not affected  Longer inversion time 15 Mousavi. M.Sc graduated in medical physics

Editor's Notes

  1. Figure 1 Coronal PD-W TSE (left) and fat suppressed PD-W TSE (right) MR images of the right knee. Fat suppressed PD-W image can visualize the bone marrow edema on the medial condyle of femur and tibia, while no lesion is highlighted on the PD-W image. Image dataset acquired at 1.5 Tesla.