The document discusses evidence-based medicine (EBM) and functional medicine. It notes that EBM aims to provide optimal health rather than just treat disease, taking a patient-centered rather than disease-centered approach. Functional medicine uses a systems-based approach and considers lifestyle, environmental, and genetic factors to identify the underlying causes of disease. It factors in influences like genomics, epigenomics, and the microbiome to build on previous paradigms and improve disease prediction and prevention strategies.