This document provides an overview and best practices for Node.js APIs and modules. It discusses streams and buffers, using streams efficiently, buffer usage and memory management. It also covers clustering to exploit multiple CPU cores, writing reusable modules, using timers for scheduling tasks, JSON for data interchange, the NPM registry, and writing native addons in C++. The presentation emphasizes hiding complexities, avoiding global state, discrete naming, and security best practices for dependencies. It cautions against tight loops, managing stream lifecycles, and large JSON processing.