Memory, Cognitive & Behavioual recovery using “BrainNext” tools:An Epilepsy patient featuring toxic encephalopathy due to Metronidazole The details about "BrainNext" tools & application

1. EPILEPSY & BEHAVIOUR
CORRECTION WITH
“BRAINNEXT”
INNOVATION & APPLICATION
DR. MANGAL KARDILE
NEUROPSYCHOLOGY, MEDICAL NEUROSCIENCE, ADVOCACY IN MENTAL HEALTH
FOUNDER – MENTAL HEALTH AIMS, INDIA
Dr. Nirmal Surya
“Epilepsy Foundation India”, Mumbai

2. CASE STUDY 1
MEMORY,
COGNITIVE &
BEHAVIOUAL
RECOVERY USING
“BRAINNEXT” TOOLS
Participant details-
R. Male, 7 yrs. old, Seizures since birth, attending
normal municipal school
Treating for basic domains with “BrainNext”
(Memory and Cognitive Rehabilitation tools)
• Cognitive domains tested & treated for R –
* behavior correction
* instruction following
* visual stability/attention span
An Epilepsy patient featuring toxic encephalopathy due to
Metronidazole

3. BEFORE
TREATMENT
PATIENT
COGNITIVE
RESPONSES
• Behaviour – extremely hyper & unacceptable for 7
yr. old child
• Scholastic performance – extremely poor,
inattentive since beginning, everyday complaints
from school, about to/forced to quit
• Object recognition & Memory – extremely poor
with no response for memory retrieval
• Speech clarity - inconsistent with lack of word
formation capacity
• Fine & gross motor – involuntary actions with lack of
purpose

4. “BRAINNEXT” TOOLS TRAINING PROGRAM
OBSERVED FOR 8 MONTHS
Neurorehabilitation training duration – 5 Feb.’2019 to 5 Nov. 2019
Testing with
“BrainNext” test
sheets -1st visit
3 visits every 15
days interval
(2 visits)
Tested domains as
follows-
*Object recognition
*Memory retrieval
*Attention span
*Following simple
instructions
*Basic strokes
rendering
(material + training)
>35%
Improvement
observed
-Object recognition
& Memory
-Attention span
-Following simple
instructions
-Basic strokes
-next level added...
>50%
Improvement
observed
-in the previous
exercises adding
higher level details
-behavior, logical
thinking, urinary
incontinence
improved
2 visits every 1
month
(2 visits)
1 visit every 2/3
months
(3 visits)
>65%
Improvement seen
-better behavior,
scholastic
performance,
improved up to
caregiver’s
satisfaction
-no further visits
required

5. “BRAINNEXT” –
MEMORY& COGNITIVE
EXERCISES
NEUROREHABILITATION
TOOL DEVELOPMENT - 2012
TO 2015
BASED ON – “SYNAPTIC
PLASTICITY CONCEPT”
(COPYRIGHT PRODUCTS)
•“BRAINNEXT”
* 500+ MEMORY & COGNITIVE BRAIN EXERCISES
* DIVIDED INTO 18 SETS
• EACH SET HAS A “TESTING PAGE” WITH INFO BOOK
* APPLIES TO ALL AGES 1 YEAR TO ELDERLY…
* SUITABLE TO ALL POPULATION
*AFFORDABLE, SAFE, EASY TO USE & DURABLE, HIGH
QUALITY
*ANY NON-CLINICAL PERSON BE TRAINED EASILY,
HAVING NO BARRIER

6. ENCOMPASSING ALMOST
ALL MEMORY &
COGNITIVE FUNCTIONS
ANY HUMAN MAY
PERFORM…..
*EACH SET HAS >15
SHEETS (LOW, MEDIUM,
HIGH LEVEL TASKS)
*ALL SETS HAVE A “TEST
PAGE” FOR ANY NON-
CLINICAL
PERSON/CAREGIVER
*EACH SET CONTAINS
INFORMATION BOOKLET
WITH STEP-BY-STEP
INSTRUCTIONS
“BrainNext” features - product overview”

7. NEUROREHABILITATION PROGRAM
AT “EPILEPSY FOUNDATION INDIA” MUMBAI
PATIENT DATA N = 193 SINCE JULY 2018…NOV.2019
PATIENTS AT EPILEPSY FOUNDATION,
MUMBAI, INDIA =134
* AGES 2.6 yrs. to 55 yrs.
• MALE & FEMALE
• VARIED REASONS FOR DEFICIT
* VARIED SOCIO-ECONOMIC CLASSES
* VARIED EDUCATIONAL BACKGROUNDS
* VARIED CULTURAL BACKGROUNDS
* DIFFERENT LANGUAGES
PARTICIPATION IN 5 EPILEPSY FREE DIST.
CIVIL HOSPITAL CAMPS N=59
* AGES 2.6 YRS. TO 55 YRS.
• MALE & FEMALE
• VARIED REASONS FOR DEFICIT
* VARIED SOCIO-ECONOMIC CLASSES
* VARIED EDUCATIONAL BACKGROUNDS
* VARIOUS CULTURAL BACKGROUNDS
* DIFFERENT LANGUAGES

8. PATIENT DATA – EPILEPSY FOUNDATION JULY 2018 TO NOV.2019
N M F
Training
duration
(months)
Age range
(years)
Neurorehab-program
Duration months no gaps
Improvement (in %)
Neurorehab-program
Duration months with
Intermittent Gaps
Improvement (in %)
84127 43 2.6 - 45 total=16
(Base condition = 0%)
(Start = 0 to 4 months)
(Caregiver support)
(Base condition = 0%)
(Start = 0 to 9 months)
(moderate Caregiver support)
(Base condition, severe to
moderate deficit N=41)
(Start = 0 – 4 months )
Improvement from basic
condition 45% to 70%
(Base condition, severe to
moderate deficit N= 84)
(Start = 0 – 9 months )
Improvement from basic
condition 25% to 55%
Visit every 15 days= 2 months
Followed by one visit each
month for 3rd & 4th months
*amongst 15 improved up to
care giver’s satisfaction,
needed no further visits
Irregular visiting pattern
07 5 5 8 - 14 total=7
<15days training, awaiting feedback

9. NEUROREHAB PROGRAM
HIGHLIGHTS…
WITHIN 5 DAYS
IMPROVEMENT SEEN…..
APART FROM YLD OF ANY
INDIVIDUAL….
MANUAL 2D & 3D INFO IS
REQ. & ACQUIRED FASTER
BY CURRENT HUMAN
BRAIN…
• EACH PATIENT IS TESTED FOR MEMORY & COGNITIVE DEFICIT AS APPLICABLE..
• CARE GIVER IS GIVEN THE TOOLS AND EXPLAINED THE PROCEDURE FOR
EACH EXERCISE (INITIALLY NOT MORE THAN 3 COGNITIVE DOMAINS ARE
TRAINED AT ONE TIME)
• TYPICALLY A 15 DAYS PROGRAM IS GIVEN, TO BE CARRIED ATLEAST 3 TO 4
HOURS IN A DAY FOR FIRST WEEK……FOR BEST RESULTS….
• CARE GIVER IS INSTRUCTED TO KEEP ALL DAYS RECORDS FOR EACH FOLLOW-
UP EVERY AFTER 15 DAYS FOR 2 MONTHS
• AFTER 15 DAYS AGAIN THE PATIENT IS TESTED FOR PRE & POST CONDITIONS
AND NEW EXERCISES ADDED, CONTINUING PREVIOUS…
• >35% IMPROVEMENT FROM THE BASIC CONDITION SEEN AFTER 1 MONTH IF
THE PROGRAM IS FOLLOWED SYSTEMATICALLY….
• AND >65% IMPROVEMENT SEEN AFTER 3 MONTHS, AS GRASPING SPEED
INCREASES, SHOWING AGE-SPECIFIC IMPROVEMENT IN LOGICAL EXPRESSION,
CRITICAL THINKING & BEHAVIOUR (NEURONS BECOME HEALTHY)…
NANO MANAGEMENT OF SENSORY
INFORMATION WORKS SUCCESSFULLY…….

10. SUMMERY
“BRAINNEXT” PATIENT
BENEFITS
LITTLE TRAINING REQUIRED
FOR
CAREGIVER/NURSES/SOCIAL
WORKERS
*DIGITAL NEUROREHAB
DEVICES IN THE MARKET
V/S
“BRAINNEXT” MANUAL INFO
FEED – GIVES MIRACULOUS
RESULTS… WITHOUT
PHYSICAL INVASION & SIDE
EFFECTS + LONG-TERM
RECOVERY
TOTAL 18 SETS WITH 500+ EXERCISES
(SPECIAL SETS FOR SEVERE DEFICIT & VISUALLY IMPAIRED)
• COST EFFECTIVE – EACH SET COSTS APPROX. BETWEEN 4000/- TO 6100/- +
18% GST AGAINST THE COSTLY HI-TECH DEVICES IN THE MARKET…
• “BRAINNEXT” 77 PAGES BOOK + CATALOGUE – IMPORTANT INFORMATION
• DURABLE, SAFE AND EASY TO USE, TRAINING PROVIDED AT ALL STEPS..
• HIGH QUALITY LAMINATED SHEETS, ACRYLIC SHAPES, BOARDS & STENCILS
WITH ADDITIONAL MATERIAL & INSTRUCTION MANUAL
• CLOTH-BASED SPECIAL FINE MOTOR EXERCISES (BASIC & ADVANCED)
• APPLICABLE TO ALL POPULATION, WILL BE AVAILABLE IN OTHER LANGUAGES
SOON….
• LITTLE TRAINING FOR THE CAREGIVER, NURSES, SOCIAL WORKERS
NEEDED….EXPANDING REHAB-TREATMENT FOR MORE NEEDY…..
• SUITABLE FOR ANY REGION IN INDIA…AND FOR GLOBAL USE…
*The “Test sheet” is useful for the caregiver where there are
scarce professional resources available in any corner of the
world, virtual support is provided as necessary….

11. FIRST EVER DECLARED
NATIONAL AWARD
FOR INNOVATION IN
NEUROREHABILITATION
• "NEUROREHABILITATION
INNOVATION OF THE YEAR
AWARD, 2019” for ‘Dr.
Mangal Kardile’ by
• INDIAN ACADEMY OF
NEUROLOGY

12. THANK YOU
Website: www.mentalhealthaims.com