This document summarizes 10 key threads or ideas from Marc Lewis's neuroscience masterworks. The threads discuss topics like addiction being a vulnerability of the nervous system, the role of feelings and meaning in our lives, how drugs activate existing chemical messengers in the brain, the brain regions involved in reward and desire, how experiences can rapidly and permanently change the brain, and how repeated neural connections are strengthened over time. Image credits are provided. The document encourages subscribing or receiving the PowerPoint slides for free from the author.