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Classification of Drugs
PRESENTED TO:
MA’AM SHAISTA IRSHAD
SUBMITTED BY:
SYED FAISAL 50409
SIDRA JALAL 50445
M.S. TAHIR 50446
MAIMOONA RASHID 50458
FIZA IFTKHAR 50463
KANWAL ALTAF 50476
Drugs:-
 Any substance that causes a change in an organism's physiology or psychology when
consumed. Drugs are typically distinguished from food and substances that provide
nutritional support. Consumption of drugs can be via inhalation, injection, smoking,
ingestion, absorptionvia apatchon the skin,ordissolution under the tongue.
 In pharmacology, a drug is a chemical substance, typically of known structure, which,
when administered to a living organism, produces a biological effect.
 A pharmaceutical drug,also called a medication or medicine,is a chemical substance used
totreat,cure,prevent,ordiagnoseadiseaseor to promotewell-being.
Classification
 A drug class is a set of medications and other compounds that have
similar chemical structures, the same mechanism of action (i.e., bind to the
same biological target), a related mode of action, and/or are used to treat
the same disease.
 A drug class is typically defined by a prototype drug, the most important,
and typically the first developed drug within the class, used as a reference
for comparison.
 Drugs are Classified on various grounds. Some of the classifications of
drugs are as follows:
 Therapeutic Classification
 Chemical Classification
 Pharmacological Classification
 Amalgamated Classification
 Legal Classification
Therapeutic Classification
 This type of categorisation of drugs is from a medical perspective and
categorises them by the pathology they are used to treat. Drug classes
that are defined by their therapeutic use (the pathology they are
intended to treat) include:
 Analgesics Sedative
 Antibiotic Antidiabetic
 Anticoagulant Cardiovascular
 Antidepressant Antipsychotic
 Anticancer Antiepileptic
 Antiviral
Chemical Classification
 This type of categorisation of drugs is from a chemical perspective and
categorises them by their chemical structure. Examples of drug classes
that are based on chemical structures include following:
 β-lactam antibiotic
 Benzodiazepine Cardiac glycoside
 Fibrate Opioid
 Thiazide diuretic Steroid
Pharmacological Classification
 Pharmacological classification is based on mechanisim of action and includes only
those drugs that have the same or similar mechanism of action. Pharmacological
classification describes drugs prosperities in a specific way. For example the
Pharmacological name of drug is benzodiazepine which is identifying by the name
‘epam’ e.g Diazepam.
 This type of categorization is from a biological perspective and categories them by
their biological target. Drug classes that share a common molecular mechanism of
action by modulating the activity of a specific biological target. 5-Alpha-reductase
inhibitor
 Angiotensin II receptor antagonist
 ACE inhibitor
 Alpha-adrenergic agonist
 Beta blocker
 Dopamine agonist
Amalgamated Classification
 The class of nonsteroidal anti-inflammatory drugs (NSAIDs) is one such example, the
wider class of anti-inflammatory drugs also comprises steroidal anti-inflammatory
drugs. These drugs were in fact the predominant anti-inflammatories during the
decade leading up to the introduction of the term "nonsteroidal anti-inflammatory
drugs". Because of the disastrous reputation that the corticosteroids had got in the
1950s, the new term, which offered to signal that an anti-inflammatory drug was not a
steroid, rapidly gained currency. The drug class of "nonsteroidal anti-inflammatory
drugs" (NSAIDs) is thus composed by one element ("anti-inflammatory") that
designates the mechanism of action, and one element ("nonsteroidal") that separates
it from other drugs with that same mechanism of action. Similarly, one might argue
that the class of disease-modifying anti-rheumatic drugs (DMARD) is composed by
one element ("disease-modifying") that albeit vaguely designates a mechanism of
action, and one element ("anti-rheumatic drug") that indicates its therapeutic use.
 Nonsteroidal anti-inflammatory drug (NSAID)
 Disease-modifying antirheumatic drug (DMARD)
Legal Classification
 There’s a large amount of disagreement even among experts on how drugs
should be classified. This means that the same drug might be categorized
differently under two different systems. Because of this, it’s virtually
impossible to create a set of defining drug classification standards. However,
here are some of the most common.
 Wondering if you or a loved one has an addiction problem? Find out in less
than 5 minutes with our confidential survey.
 Difference between legal and illegal drug
 Legal drugs can either be bought over-the-counter or with a prescription
from a medical doctor. Illegal drugs cannot legally be manufactured, bought
or sold in the world. And some other drugs are legal in some situations
but illegal when abused.
What are illegal drugs?
 A drug is a substance that affects the way the body functions. If a drug is classified as
‘illegal’, this means that it is forbidden by law. Different illegal drugs have different effects on
people and these effects are influenced by many factors. This makes them unpredictable
and dangerous, especially for young people.
 Types of illegal drugs
 Below are some types of illegal drugs.
 Cannabis
 Cocaine
 Hallucinogens
 Heroin
 Inhalants
 Ketamine
 Methamphetamine
Effects of Drugs
Different types of drugs affect your body in different ways, and the effects associated with
drugs can vary from person to person.
How a drug effects an individual is dependent on a variety of factors including body size,
general health, the amount and strength of the drug, and whether any other drugs are in
the system at the same time.
Drugs can have short-term and long-term effects. These effects can be physical and
psychological, and can include dependency.
Drugs affect body's central nervous system. They affect how you think, feel and behave. The
three main types are depressants, hallucinogens and stimulants:
Depressants
 Depressants slow or 'depress' the function of the central nervous system. They slow the
messages going to and from your brain. In small quantities depressants can cause a
person to feel relaxed and less inhibited. In large amounts they may cause vomiting,
unconsciousness and death. Depressants affect your concentration and coordination,
and slow your ability to respond to situations. It is important to not operate heavy
machinery while taking depressants. Alcohol, cannabis, GHB, opiates (heroin,
morphine, codeine) and benzodiazepines (minor tranquillisers) are examples of
depressants.
Hallucinogens
 Hallucinogens distort your sense of reality. You may see or hear things that are not
really there, or see things in a distorted way. Other effects can include emotional and
psychological euphoria, jaw clenching, panic, paranoia, gastric upset and nausea.
Ketamine, LSD, PCP, 'magic mushrooms' and cannabis are examples of hallucinogens.
Stimulants
 Stimulants speed or 'stimulate' the central nervous system. They speed up messaging
to and from the brain, making you feel more alert and confident. This can cause
increased heart rate, blood pressure and body temperature, reduced appetite,
agitation and sleeplessness. In large amounts stimulants may cause anxiety, panic,
seizures, stomach cramps and paranoia. Caffeine, nicotine, amphetamines (speed and
Ice), cocaine and ecstasy (MDMA) are examples of stimulants.
Risk factors for drug-related harm
 The effects of a drug, and how long they last, depend on a number of
factors:
 The type and strength of drugs that you use
 How the drug was made -- substances manufactured in home labs may
contain bacteria, dangerous chemicals and other unsafe substances, and
have an unknown strength. Even one dose may cause an overdose that
leads to brain damage or death
 Your physical characteristics (including height, weight, age, body fat and
metabolism)
 The dose that you take
 How often and for how long you have been using drugs
 How you ingest the drug (by inhalation, by injection or orally). Compared with
swallowing a drug, inhalation and injection are more likely to lead to overdose and
dependence. If you are injecting drugs, sharing injecting equipment will increase
your risk of contracting serious diseases such as hepatitis and HIV. It will also
increase your risk of serious infection
 Mental health, mood and environment (that is, whether you are in a secure, happy
place or an unsafe place) can affect the experience you have when taking drugs. If
you have a mental health condition, drugs may exacerbate or complicate the
symptoms of that condition
 Whether you mix drugs, including alcohol. In particular, alcohol use may lead to
high risk behaviour (such as drink driving) which can result in the serious injury or
death of yourself or others.
Physical harms from drug use
 Drug use can affect short- and long-term health outcomes. Some of these health
outcomes can be serious, and possibly irreversible.
 Drug use can lead to risky or out of character behaviour.
 You are more likely to have an accident (at home, in a car, or wherever you are).
 You may be vulnerable to sexual assault or you may engage in unprotected sex. Either
of these could lead to pregnancy and sexually transmitted infection.
 You could commit a sexual assault or other violent act.
 You may find it hard to sleep, think, reason, remember and solve problems.
 Drug use can also result in long-term health outcomes that include:
 Harm to organs and systems in your body, such as your throat, stomach, lungs, liver,
pancreas, heart, brain, nervous system
 Cancer (such as lung cancer from inhaling drugs)
 Infectious disease, from shared injecting equipment and increased incidence of risk-
taking behaviors
 Harm to your baby, if you are pregnant
 Acne, or skin lesions if the drug you are taking causes you to pick or scratch at your skin
 Needle marks and collapsed veins, if you inject regularly
 Baldness
 Male pattern hair growth in women, such as facial hair
 Jaw and teeth issues due to clenching and grinding your teeth; or bad breath, teeth
cavities and gum disease
 Mood swings and erratic behavior
 Addiction
 Psychosis (losing touch with reality)
 Accidental overdose
 Higher risk of mental illness, depression, suicide and death.
Cannabis (hash, pot, dope, weed,
grass, skunk, marijuana)
 May cause relaxation and altered perception
 Can lead to increased heart rate and low blood pressure
 Can make you feel relaxed and happy, but can also cause lethargy, anxiety, paranoia, and
psychosis in extreme cases. A history or family history of mental illness may increase the
possibility of more extreme psychotic reactions
 It is linked to mental health problems such as schizophrenia and, when smoked, to lung
diseases such as asthma, chronic bronchitis and lung, throat, mouth and tongue cancer
 Affects how your brain works. Regular use can make it hard for you to
concentrate, learn and retain information
 Reduces your fertility
 When mixed with tobacco, is likely to increase the risk of heart disease and
lung cancer.
Cocaine (powder cocaine, coke, blow,
Charlie, crack)
 gives you increased energy
 makes you feel happy, awake, confident and less inhibited, but has a nasty
'come down' that makes you feel depressed and unwell. (Using depressant
drugs to help with the severity of come downs can increase the chances of the
development of negative cycles of dependence.)
 can overstimulate the heart and nervous system and lead to a seizure, brain
haemorrhage, stroke or heart attack (people have died from cocaine-induced
heart failure)
 reduces your pain perception and may result in injury
 carries greater risk if mixed with alcohol or other stimulants, especially if you
have high blood pressure or if you have an existing heart condition
 can harm your baby during pregnancy, and may cause miscarriage
 can increase the risk of mental health issues such a s anxiety, paranoia and
psychosis
 if snorted, can cause damage to the lining of the nasal passage and nose
 if injected, can cause vein collapse and increased risk of HIV and hepatitis
infection.
Mephedrone (meow meow, m-cat,
plant food, bubble, meph)
can induce feelings of happiness, euphoria and confidence, but can also cause
anxiety and paranoia
 causes vomiting, sweating and headaches in some users
 can overstimulate your heart and nervous system
 can cause periods of insomnia
 can lead to fits and agitated and hallucinatory states
 if used in large amounts, can cause tingling of the hands and feet, seizure and
respiratory failure
 has been linked to a number of deaths
 if injected, can cause vein collapse and increases the risk of HIV and hepatitis
infection.
Ecstasy (MDMA, pills, E, eckies)
 can make you feel alert, warm and chatty
 can make sounds and colours seem more intense
 may cause anxiety, confusion, paranoia and even psychosis
 is linked (in cases of long-term use) to memory loss, depression and
anxiety
 can lead to overheating and dehydration
 tends to stop your body producing enough urine, so your body retains
fluid.
Speed (amphetamine, billy, whizz)
 can make you feel alert, confident and energetic
 can reduce appetite
 may make you agitated and aggressive
 may cause confusion, paranoia and even psychosis
 can make you very depressed and lethargic for hours or days, when used a
lot
 can cause high blood pressure and heart attacks
 is more risky if mixed with alcohol, or if you have blood pressure or heart
problems
 puts you at risk of overdose, vein and tissue damage, and infectious
disease (such as hepatitis C and HIV), if you inject speed.
Ice (crystal meth, shabu, crystal, glass,
shard, P)
 may create feelings of pleasure and confidence
 can make you feel alert and energetic
 can cause you to repeat simple things like itching and scratching
 can cause enlarged or dilated pupils and a dry mouth
 may make you grind your teeth
 can cause excessive sweat
 can increase your heart rate and breathing
 may reduce your appetite
 may increase your sex drive
 puts you at risk of infectious diseases (such as hepatitis B, hepatitis C and
HIV) if you inject it
 can damage your nasal passages and cause nose bleeds if you snort it.
Effects of a 'come down'
 A 'come down' is your body's reaction to the substances that you have taken,
after the initial reaction. In other words, it is the after effect.
 How long it lasts, and how bad it is, depends on the type of drug (stimulant or
depressant) and your age, sex and tolerance.
 Common after effects are flatness, depression and exhaustion. Or you may feel:
 shaky, dizzy, sweaty
 headachey
 nauseous
 fatigued
 not hungry
 sleepy or unable to sleep.
Classification of Drugs: A Concise Overview
Classification of Drugs: A Concise Overview

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Classification of Drugs: A Concise Overview

  • 1.
  • 2.
  • 3. Classification of Drugs PRESENTED TO: MA’AM SHAISTA IRSHAD SUBMITTED BY: SYED FAISAL 50409 SIDRA JALAL 50445 M.S. TAHIR 50446 MAIMOONA RASHID 50458 FIZA IFTKHAR 50463 KANWAL ALTAF 50476
  • 4. Drugs:-  Any substance that causes a change in an organism's physiology or psychology when consumed. Drugs are typically distinguished from food and substances that provide nutritional support. Consumption of drugs can be via inhalation, injection, smoking, ingestion, absorptionvia apatchon the skin,ordissolution under the tongue.  In pharmacology, a drug is a chemical substance, typically of known structure, which, when administered to a living organism, produces a biological effect.  A pharmaceutical drug,also called a medication or medicine,is a chemical substance used totreat,cure,prevent,ordiagnoseadiseaseor to promotewell-being.
  • 5. Classification  A drug class is a set of medications and other compounds that have similar chemical structures, the same mechanism of action (i.e., bind to the same biological target), a related mode of action, and/or are used to treat the same disease.  A drug class is typically defined by a prototype drug, the most important, and typically the first developed drug within the class, used as a reference for comparison.
  • 6.  Drugs are Classified on various grounds. Some of the classifications of drugs are as follows:  Therapeutic Classification  Chemical Classification  Pharmacological Classification  Amalgamated Classification  Legal Classification
  • 7. Therapeutic Classification  This type of categorisation of drugs is from a medical perspective and categorises them by the pathology they are used to treat. Drug classes that are defined by their therapeutic use (the pathology they are intended to treat) include:  Analgesics Sedative  Antibiotic Antidiabetic  Anticoagulant Cardiovascular  Antidepressant Antipsychotic  Anticancer Antiepileptic  Antiviral
  • 8. Chemical Classification  This type of categorisation of drugs is from a chemical perspective and categorises them by their chemical structure. Examples of drug classes that are based on chemical structures include following:  β-lactam antibiotic  Benzodiazepine Cardiac glycoside  Fibrate Opioid  Thiazide diuretic Steroid
  • 9. Pharmacological Classification  Pharmacological classification is based on mechanisim of action and includes only those drugs that have the same or similar mechanism of action. Pharmacological classification describes drugs prosperities in a specific way. For example the Pharmacological name of drug is benzodiazepine which is identifying by the name ‘epam’ e.g Diazepam.  This type of categorization is from a biological perspective and categories them by their biological target. Drug classes that share a common molecular mechanism of action by modulating the activity of a specific biological target. 5-Alpha-reductase inhibitor  Angiotensin II receptor antagonist  ACE inhibitor  Alpha-adrenergic agonist  Beta blocker  Dopamine agonist
  • 10. Amalgamated Classification  The class of nonsteroidal anti-inflammatory drugs (NSAIDs) is one such example, the wider class of anti-inflammatory drugs also comprises steroidal anti-inflammatory drugs. These drugs were in fact the predominant anti-inflammatories during the decade leading up to the introduction of the term "nonsteroidal anti-inflammatory drugs". Because of the disastrous reputation that the corticosteroids had got in the 1950s, the new term, which offered to signal that an anti-inflammatory drug was not a steroid, rapidly gained currency. The drug class of "nonsteroidal anti-inflammatory drugs" (NSAIDs) is thus composed by one element ("anti-inflammatory") that designates the mechanism of action, and one element ("nonsteroidal") that separates it from other drugs with that same mechanism of action. Similarly, one might argue that the class of disease-modifying anti-rheumatic drugs (DMARD) is composed by one element ("disease-modifying") that albeit vaguely designates a mechanism of action, and one element ("anti-rheumatic drug") that indicates its therapeutic use.  Nonsteroidal anti-inflammatory drug (NSAID)  Disease-modifying antirheumatic drug (DMARD)
  • 11. Legal Classification  There’s a large amount of disagreement even among experts on how drugs should be classified. This means that the same drug might be categorized differently under two different systems. Because of this, it’s virtually impossible to create a set of defining drug classification standards. However, here are some of the most common.  Wondering if you or a loved one has an addiction problem? Find out in less than 5 minutes with our confidential survey.  Difference between legal and illegal drug  Legal drugs can either be bought over-the-counter or with a prescription from a medical doctor. Illegal drugs cannot legally be manufactured, bought or sold in the world. And some other drugs are legal in some situations but illegal when abused.
  • 12. What are illegal drugs?  A drug is a substance that affects the way the body functions. If a drug is classified as ‘illegal’, this means that it is forbidden by law. Different illegal drugs have different effects on people and these effects are influenced by many factors. This makes them unpredictable and dangerous, especially for young people.  Types of illegal drugs  Below are some types of illegal drugs.  Cannabis  Cocaine  Hallucinogens  Heroin  Inhalants  Ketamine  Methamphetamine
  • 13.
  • 14. Effects of Drugs Different types of drugs affect your body in different ways, and the effects associated with drugs can vary from person to person. How a drug effects an individual is dependent on a variety of factors including body size, general health, the amount and strength of the drug, and whether any other drugs are in the system at the same time. Drugs can have short-term and long-term effects. These effects can be physical and psychological, and can include dependency. Drugs affect body's central nervous system. They affect how you think, feel and behave. The three main types are depressants, hallucinogens and stimulants:
  • 15. Depressants  Depressants slow or 'depress' the function of the central nervous system. They slow the messages going to and from your brain. In small quantities depressants can cause a person to feel relaxed and less inhibited. In large amounts they may cause vomiting, unconsciousness and death. Depressants affect your concentration and coordination, and slow your ability to respond to situations. It is important to not operate heavy machinery while taking depressants. Alcohol, cannabis, GHB, opiates (heroin, morphine, codeine) and benzodiazepines (minor tranquillisers) are examples of depressants.
  • 16. Hallucinogens  Hallucinogens distort your sense of reality. You may see or hear things that are not really there, or see things in a distorted way. Other effects can include emotional and psychological euphoria, jaw clenching, panic, paranoia, gastric upset and nausea. Ketamine, LSD, PCP, 'magic mushrooms' and cannabis are examples of hallucinogens.
  • 17. Stimulants  Stimulants speed or 'stimulate' the central nervous system. They speed up messaging to and from the brain, making you feel more alert and confident. This can cause increased heart rate, blood pressure and body temperature, reduced appetite, agitation and sleeplessness. In large amounts stimulants may cause anxiety, panic, seizures, stomach cramps and paranoia. Caffeine, nicotine, amphetamines (speed and Ice), cocaine and ecstasy (MDMA) are examples of stimulants.
  • 18.
  • 19. Risk factors for drug-related harm  The effects of a drug, and how long they last, depend on a number of factors:  The type and strength of drugs that you use  How the drug was made -- substances manufactured in home labs may contain bacteria, dangerous chemicals and other unsafe substances, and have an unknown strength. Even one dose may cause an overdose that leads to brain damage or death  Your physical characteristics (including height, weight, age, body fat and metabolism)  The dose that you take
  • 20.  How often and for how long you have been using drugs  How you ingest the drug (by inhalation, by injection or orally). Compared with swallowing a drug, inhalation and injection are more likely to lead to overdose and dependence. If you are injecting drugs, sharing injecting equipment will increase your risk of contracting serious diseases such as hepatitis and HIV. It will also increase your risk of serious infection  Mental health, mood and environment (that is, whether you are in a secure, happy place or an unsafe place) can affect the experience you have when taking drugs. If you have a mental health condition, drugs may exacerbate or complicate the symptoms of that condition  Whether you mix drugs, including alcohol. In particular, alcohol use may lead to high risk behaviour (such as drink driving) which can result in the serious injury or death of yourself or others.
  • 21. Physical harms from drug use  Drug use can affect short- and long-term health outcomes. Some of these health outcomes can be serious, and possibly irreversible.  Drug use can lead to risky or out of character behaviour.  You are more likely to have an accident (at home, in a car, or wherever you are).  You may be vulnerable to sexual assault or you may engage in unprotected sex. Either of these could lead to pregnancy and sexually transmitted infection.  You could commit a sexual assault or other violent act.  You may find it hard to sleep, think, reason, remember and solve problems.
  • 22.  Drug use can also result in long-term health outcomes that include:  Harm to organs and systems in your body, such as your throat, stomach, lungs, liver, pancreas, heart, brain, nervous system  Cancer (such as lung cancer from inhaling drugs)  Infectious disease, from shared injecting equipment and increased incidence of risk- taking behaviors  Harm to your baby, if you are pregnant  Acne, or skin lesions if the drug you are taking causes you to pick or scratch at your skin
  • 23.  Needle marks and collapsed veins, if you inject regularly  Baldness  Male pattern hair growth in women, such as facial hair  Jaw and teeth issues due to clenching and grinding your teeth; or bad breath, teeth cavities and gum disease  Mood swings and erratic behavior  Addiction  Psychosis (losing touch with reality)  Accidental overdose  Higher risk of mental illness, depression, suicide and death.
  • 24. Cannabis (hash, pot, dope, weed, grass, skunk, marijuana)  May cause relaxation and altered perception  Can lead to increased heart rate and low blood pressure  Can make you feel relaxed and happy, but can also cause lethargy, anxiety, paranoia, and psychosis in extreme cases. A history or family history of mental illness may increase the possibility of more extreme psychotic reactions  It is linked to mental health problems such as schizophrenia and, when smoked, to lung diseases such as asthma, chronic bronchitis and lung, throat, mouth and tongue cancer
  • 25.  Affects how your brain works. Regular use can make it hard for you to concentrate, learn and retain information  Reduces your fertility  When mixed with tobacco, is likely to increase the risk of heart disease and lung cancer.
  • 26. Cocaine (powder cocaine, coke, blow, Charlie, crack)  gives you increased energy  makes you feel happy, awake, confident and less inhibited, but has a nasty 'come down' that makes you feel depressed and unwell. (Using depressant drugs to help with the severity of come downs can increase the chances of the development of negative cycles of dependence.)  can overstimulate the heart and nervous system and lead to a seizure, brain haemorrhage, stroke or heart attack (people have died from cocaine-induced heart failure)  reduces your pain perception and may result in injury  carries greater risk if mixed with alcohol or other stimulants, especially if you have high blood pressure or if you have an existing heart condition
  • 27.  can harm your baby during pregnancy, and may cause miscarriage  can increase the risk of mental health issues such a s anxiety, paranoia and psychosis  if snorted, can cause damage to the lining of the nasal passage and nose  if injected, can cause vein collapse and increased risk of HIV and hepatitis infection.
  • 28. Mephedrone (meow meow, m-cat, plant food, bubble, meph) can induce feelings of happiness, euphoria and confidence, but can also cause anxiety and paranoia  causes vomiting, sweating and headaches in some users  can overstimulate your heart and nervous system  can cause periods of insomnia  can lead to fits and agitated and hallucinatory states  if used in large amounts, can cause tingling of the hands and feet, seizure and respiratory failure  has been linked to a number of deaths  if injected, can cause vein collapse and increases the risk of HIV and hepatitis infection.
  • 29. Ecstasy (MDMA, pills, E, eckies)  can make you feel alert, warm and chatty  can make sounds and colours seem more intense  may cause anxiety, confusion, paranoia and even psychosis  is linked (in cases of long-term use) to memory loss, depression and anxiety  can lead to overheating and dehydration  tends to stop your body producing enough urine, so your body retains fluid.
  • 30. Speed (amphetamine, billy, whizz)  can make you feel alert, confident and energetic  can reduce appetite  may make you agitated and aggressive  may cause confusion, paranoia and even psychosis  can make you very depressed and lethargic for hours or days, when used a lot  can cause high blood pressure and heart attacks  is more risky if mixed with alcohol, or if you have blood pressure or heart problems  puts you at risk of overdose, vein and tissue damage, and infectious disease (such as hepatitis C and HIV), if you inject speed.
  • 31. Ice (crystal meth, shabu, crystal, glass, shard, P)  may create feelings of pleasure and confidence  can make you feel alert and energetic  can cause you to repeat simple things like itching and scratching  can cause enlarged or dilated pupils and a dry mouth  may make you grind your teeth  can cause excessive sweat  can increase your heart rate and breathing
  • 32.  may reduce your appetite  may increase your sex drive  puts you at risk of infectious diseases (such as hepatitis B, hepatitis C and HIV) if you inject it  can damage your nasal passages and cause nose bleeds if you snort it.
  • 33. Effects of a 'come down'  A 'come down' is your body's reaction to the substances that you have taken, after the initial reaction. In other words, it is the after effect.  How long it lasts, and how bad it is, depends on the type of drug (stimulant or depressant) and your age, sex and tolerance.  Common after effects are flatness, depression and exhaustion. Or you may feel:  shaky, dizzy, sweaty  headachey  nauseous  fatigued  not hungry  sleepy or unable to sleep.