The document discusses EGFR internalization through different mechanisms, including kinase-dependent and kinase-independent internalization induced by dimerization. It also discusses using nanobodies against EGFR for applications such as stimulating EGFR transport and degradation through oligomerization and localization to intracellular compartments. Specifically, it evaluates different anti-EGFR nanobodies for their epitope specificity, affinities, ability to compete with EGF or not, and impact on EGFR internalization and transport.
Today, mobile is the most brand touchpoint with your consumer. It’s the last think they touch at night and the first thing they touch in the morning. Many brands are in digital angst, in fear of getting it wrong. Think of it as another marketing channel. Make sure you have a strong brand strategy. And execute it wisely.
Find out how Added Value can help you at the 2014 Mobile World Congress.
#MWC2014
3 giorni di formazione in aula a Roma (presso l'Hotel Regent****) e Milano (presso le sale Spaziper) per parlare di Social Media Marketing, Facebook Marketing, Campagne di comunicazione online e Wordpress!
Special partner Fotolia!
IN THIS SUMMARY
Can heightened awareness, a focus on personal strengths, and intentional thinking create positive results? In Seeing Red Cars, author and consultant Laura Goodrich aims to prove that they can, and takes participants through a guided process that can help individuals and organizations achieve such results. Backed by Goodrich’s 15 years of consulting experience and research about how people are able to make positive changes, the Seeing Red Cars mind-set is a significant shift from business-as-usual. The Seeing Red Cars Toolkit contains 12 activities that individuals or organizations can complete, culminating in a 52-week action plan to help people achieve the success they truly desire.
SUBSCRIBE TODAY
http://www.bizsum.com/summaries/seeing-red-cars
Sadhana and the Indo Tibetan Tradition (commentary on 'Reimagining the Buddha') - a talk by Kamalashila given on 6 Feb 2011at the Men's Order Weekend, Padmaloka
Today, mobile is the most brand touchpoint with your consumer. It’s the last think they touch at night and the first thing they touch in the morning. Many brands are in digital angst, in fear of getting it wrong. Think of it as another marketing channel. Make sure you have a strong brand strategy. And execute it wisely.
Find out how Added Value can help you at the 2014 Mobile World Congress.
#MWC2014
3 giorni di formazione in aula a Roma (presso l'Hotel Regent****) e Milano (presso le sale Spaziper) per parlare di Social Media Marketing, Facebook Marketing, Campagne di comunicazione online e Wordpress!
Special partner Fotolia!
IN THIS SUMMARY
Can heightened awareness, a focus on personal strengths, and intentional thinking create positive results? In Seeing Red Cars, author and consultant Laura Goodrich aims to prove that they can, and takes participants through a guided process that can help individuals and organizations achieve such results. Backed by Goodrich’s 15 years of consulting experience and research about how people are able to make positive changes, the Seeing Red Cars mind-set is a significant shift from business-as-usual. The Seeing Red Cars Toolkit contains 12 activities that individuals or organizations can complete, culminating in a 52-week action plan to help people achieve the success they truly desire.
SUBSCRIBE TODAY
http://www.bizsum.com/summaries/seeing-red-cars
Sadhana and the Indo Tibetan Tradition (commentary on 'Reimagining the Buddha') - a talk by Kamalashila given on 6 Feb 2011at the Men's Order Weekend, Padmaloka
22. Epitope specificity anti-EGFR NBs 7D12 Dom III 9G8 Dom II/III EgB4 Dom IV EgC9 Dom I 7D12 Plasma membrane Tyrosine kinase Rob Roovers IV III II I 9G8 EgB4 EgC9