Diclofenac compound Research contains : 1- Introduction about The Pharmacological Class. 2- Name of the drug (IUPAC, generic and trade names). 3- Structure of the drug (drawn by Chemsketch program). 4- Synthesis of the drug (drawn by Chemsketch program). 5- Spectral data of the drug (UV, IR, NMR and Mass). 6- Uses, Side effects and Contraindications.

2. Research On
Non Steroidal Anti-Inflammatory Drugs
(NSAIDs)

3. Diclofenac Research
Content :
1- Introduction about The Pharmacological Class.
2- Name of the drug (IUPAC, generic and trade names).
3- Structure of the drug (drawn by Chemsketch program).
4- Synthesis of the drug (drawn by Chemsketch program).
5- Spectral data of the drug (UV, IR, NMR and Mass).
6- Uses, Side effects and Contraindications.
7- A table describing the role of each student in the group in
fulfilling the project.

4. Diclofenac Research
The Pharmacological Class
•
Diclofenac belongs to the class of acetic acid derivatives
and related substances of non-steroidal antiinflammatory and antirheumatic products.
•
This medicine works by reducing substances in the body
that cause pain and inflammation.
•
Diclofenac is used to treat pain or inflammation caused
by arthritis or ankylosing spondylitis.

5. Diclofenac Research
IUPAC, Generic & Trade Names
• IUPAC Name:
2-(2,6-dichloranilino) phenylacetic acid.
• Generic Name:
Diclofenac Sodium, Diclofenac Potassium &
epolamine.
• Trade Name:
Diclofenac

6. Diclofenac Research
Diclofenac Potassium
Diclofenac epolamine
Diclofenac Sodium
Diclofenac (as free acid)

7. Diclofenac Research
Structure of Drug
Diclofenac_3D

8. Diclofenac Research
Synthesis of the drug

9. Diclofenac Research
Spectral Data of the Drug
IR
Diclofenac Sodium

10. Diclofenac Research
Spectral Data of the Drug
UV
Spectrum of Diclofenac in NaOH

11. Diclofenac Research
Spectral Data of the Drug
NMR

12. Diclofenac Research
Spectral Data of the Drug
Mass

13. Diclofenac Research
Uses
• Diclofenac is used to treat pain, inflammatory disorders,
and dysmenorrhea.
• Diclofenac is used commonly to treat mild to moderate
postoperative or post-traumatic pain, in particular when
inflammation is also present, and is effective against
menstrual pain and endometriosis.

14. Diclofenac Research
Side Effects
• This medicine may cause life-threatening heart or
circulation problems such as heart attack or stroke,
especially if you use it long term.
• This medicine may also cause serious effects on the
stomach or intestines, including bleeding or perforation
(forming of a hole).

15. Diclofenac Research
Contraindication
• Do not use diclofenac just before or after heart bypass
surgery (coronary artery bypass graft, or CABG).
• Diclofenac is contraindicated in hypersensitivity, active
peptic ulcer, moderate to severe hepatic disease and in
pregnancy.
• Those with Alcohol abuse, Colitis, Crohn's disease,
diverticulitis, gastric ulcer, Diabetes mellitus,
Hemorrhoids, Hepatitis, renal disease, Rectal irritation.