WHAT IS MACHINE LEARNING:
• Machine learning is a part of artificial intelligence that helps
computers find patterns in data. This allows them to make
predictions on new data.
• There are 4 different types of machine learining:
1) Supervised learning.
2) Unsupervised learning.
3) Semi-supervised learning.
4) Reinforcement learning.
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WHAT IS SITE SELECTION
Site selection is the process of examining multiple options and assessing their
relative advantages and disadvantages. Site selection comes after the needs
assessment is completed. If you select a site before the needs assessment, you
may compromise on key design aspects due to site limitations.
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FACTORS INFLUENCING SITE SELECTION
1) Staff Qualifications:
Take into consideration the staff availability, their credentials, their experience
in clinical research and how their performance adheres to regulatory and ethical
guidelines.
2) Facilities and Equipment:
Does the facility have adequate space available for the clinical trial, drug and
device storage space, storage of important documents and equipment needed
for the study?
3) Site Profile and Timelines:
What kind of site is it? (hospital, clinical, non-profit, government or private
site), what is the site’s Institutional Review Board (IRB) meeting timeframe
and contract negotiation timeline?
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4) Population Profile and Access:
Takes into consideration the eligible participants availability and proximity to
the site, their condition, any similar ongoing trials, recruitment capabilities and
the resources available for conducting research.
5) Past Performance:
Look into the past clinical trials conducted at the site, especially trials that had
similar enrollment timelines, enrollment targets and past enrollment rates.
6) Competition:
Look at any current trials which target the same population profile. Are the
trials taking place in close proximity to your site? (This would have an impact
on participant recruitment).
7) Location:
Is the site located in a central area that is easy for participants to get to? Is it
close to amenities, including public transport, airports and hotels (for interstate
and international participants)?
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WHAT IS DATA DRIVEN MACHINE
LEARNING
• Data-driven machine learning is at the heart of many modern
applications, from recommendation systems and autonomous
vehicles to medical diagnostics and financial forecasting. Its
success hinges on the quality of the data and the appropriateness
of the chosen models and techniques.
• This paradigm leverages data to train algorithms, allowing them
to learn patterns, make predictions, and improve performance
over time. Here are some key aspects of data-driven machine
learning:
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DIFFERENT TYPES STEPS OF DATA DRIVEN
MACHINE LEARNING:
1)Data Collection:
2)Data Preparation:
3)Feature Engineering:
4)Model Selection:
5)Training:
6)Validation and Testing:
7)Hyperparameter Tuning:
8)Deployment:
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DIFFERENT TYPES OF DATA:
• Internal Data: Gather historical performance data, sales
figures, customer demographics, and any other relevant
information about existing sites.
• External Data: Incorporate external datasets such as
demographic data, economic indicators, traffic patterns,
competitor locations, weather data, and more.
• Geospatial Data: Utilize geospatial data such as maps,
satellite imagery
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CHALLENGES :
1) DATA PRIVACY AND SECURITY:
In the realm of Big Data Analytics and Machine Learning, data
privacy and security emerge as paramount concerns. As
organizations and research institutions gather and analyze vast
amounts of data, ensuring the protection of sensitive information
becomes crucial.
2) Security Threats:
The proliferation of data also attracts malicious entities aiming to
exploit vulnerabilities. Threats such as data breaches, unauthorized
access, and cyber-attacks pose significant risks.
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3) Regulatory Compliance:
As data privacy regulations, such as the General Data Protection
Regulation (GDPR) and the California Consumer Privacy Act
(CCPA), become more stringent, organizations must adhere to
regulatory frameworks. Non-compliance not only leads to legal
repercussions but also erodes trust among stakeholders.
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REAL WORLD HEALTH CARE
APPLICATION:
• In the realm of healthcare, Big Data Analytics (BDA) combined
with Machine Learning (ML) has revolutionized the landscape of
medical diagnosis and patient care. The integration of electronic
health records, genomic data, medical imaging, and real-time
monitoring devices has enabled healthcare professionals to
extract actionable insights, predict potential health risks, and
personalize treatment plans. BDA facilitates the analysis of vast
datasets to identify patterns, anomalies, and correlations that may
not be apparent through traditional methods. ML algorithms,
ranging from supervised learning for predictive modeling to deep
learning for image and signal processing, play a pivotal role in
extracting meaningful information from these complex datasets.
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• For instance, in diagnostic imaging, ML algorithms can analyze
medical images such as X-rays, MRIs, and CT scans to detect
abnormalities, tumors, or early signs of diseases with high
accuracy. Similarly, predictive models can assess a patient's
risk factors based on their medical history, genetic
predisposition, and lifestyle factors to preemptively identify and
mitigate potential health issues.
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REFERENCES:
• 1)https://www.researchgate.net/publication/378108443_L
everaging_Big_Data_Analytics_to_Enhance_Machine_Lear
ning_Algorithms
• 2)https://www.advarra.com/blog/strategies-for-successful-
site-selection-in-clinical-trials/
• 3)https://www.sas.com/en_gb/insights/articles/analytics/m
achine-learning-
algorithms.html#:~:text=There%20are%20four%20types
%20of,%2Dsupervised%2C%20unsupervised%20and%20
reinforcement.
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Thank You!
www.clinosol.com
(India | Canada)
9121151622/623/624
info@clinosol.com
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Data-Driven Site Selection: Leveraging Machine Learning