CVT

1. Cerebral Venous Thrombosis
(CVT)
Overview for Clinical Presentation

2. Definition
• • CVT is thrombosis of the dural venous
sinuses and/or cerebral veins
• • Leads to impaired venous drainage, raised
ICP, and venous infarction

3. Risk Factors
• • Prothrombotic states (Protein C/S deficiency,
Factor V Leiden)
• • Pregnancy and postpartum
• • Oral contraceptive pills
• • Infections (otitis, mastoiditis)
• • Malignancy
• • Dehydration
• • Systemic inflammatory disorders

4. Clinical Features
• • Headache (most common)
• • Seizures
• • Focal neurological deficits
• • Papilledema
• • Altered sensorium
• • Signs of raised intracranial pressure

5. Diagnosis
• • MRI with MRV – investigation of choice
• • CT Venography – fast and useful
• • D-dimer may be elevated but not diagnostic
• • Ophthalmic exam for papilledema

6. Treatment
• • Anticoagulation: LMWH followed by
warfarin/DOAC
• • Treat underlying cause
• • Manage raised ICP
• • Thrombolysis/endovascular therapy
(selected cases)

7. Prognosis
• • Generally good with early diagnosis and
treatment
• • Mortality ~5–10%
• • Seizures and neurological deficits may
persist in some patients