Pham Van-Hau is a PhD candidate in biochemistry at Laval University in Quebec, Canada. He has extensive experience in protein biochemistry techniques and has worked on projects involving enzyme purification, characterization, and inhibition. He has also taught undergraduate courses and trained students in biochemical techniques and protein bioinformatics. Upon completing his PhD, he will have researched novel inhibitors of the tRNA-dependent amidotransferase of Helicobacter pylori.

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PHAM Van-Hau
938 Rue Pouliot, Québec (QC), Canada; tel: +1 418-264-9953
Email: van-hau.pham.1@ulaval.ca; https://ca.linkedin.com/in/phamvanhau
Functional languages: English, French and Vietnamese
EDUCATION
PhD in Biochemistry Expect to finish in August 2016
Laval University, Quebec, Canada
Master in food science 2003-2004
University of Montpellier II, France
Engineer in food technology 1998-2003
Can Tho University, Vietnam
SPECIFIC COMPETENCES
- Writing scientific papers; organizing well workflow, team-work, and respecting deadlines
- Overproduction of recombinant proteins and transfer RNA; DNA extraction and manipulation (PCR),
site-direct mutagenesis, cellular extraction by French pressure, Virsonic
- Protein informatics tools: Uniprot, Pubmed, Pymol, clustalW and Mega5; Notions in Python
- Electrophoresis of proteins, DNA and tRNA (Native-PAGE, substrate-PAGE, SDS-PAGE)
- HPLC-AKTA purification system, and thin-layer chromatography
- Bacteriophage-relating techniques: culture, titering, storage, precipitation of genetic materials
- Purification and analysis of proteases: bromelain, papain, trypsin-like proteases
- Characterization of enzymes: Kinetic measurement (Kaleidagraph)
- In vivo analysis of effect of novel compounds on pathogenic bacteria: Pseudomonas aeruginosa,
Staphylococcus aureus, Enterococcus faecalis and Escherichia coli (IC50, antimicrobial susceptibility
testing)- Strong skills for biochemical techniques: solution, pH, buffer, dilution, pipet, balance
- Analysis of foods: pH, proteins, lipids, carbohydrates, water content, food texture TAXT2
WORK EXPERIENCES
1) PhD candidate 2009-2016
Laval University, Quebec (Including one-year preparation to fulfill admission requirement)

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- Conducted the thesis: Novel inhibitors of the tRNA-dependent amidotransferase of
Helicobacter pylori: Dipeptide-like compounds and peptides generated by phage display
- Assisted to teach the following courses:
o Laboratory (lab) of general microbiology (BIO-1003) 2012
(Mme Marie-Claude Julien, Département de phytologie)
o Lab of biochemical techniques (BCM-1902 and BCM-1004) 2011-2013
(Mr. Louis-André Lortie, Département de Biochimie et microbiologie)
o Lab of proteins and enzymology (BCM-3003) 2012
(Mr. Louis-André Lortie, Département de Biochimie et microbiologie)
- Trained on Protein bioinformatics at National Institute of Health (USA) 2011
o Performing DNA and protein alignments
o Exploiting date on UniProt and PubMed
o Constructing models of proteins via Chimeras
o Using Pymol to produce publishable pictures
- Followed courses: Bioinformatics 1 (BIF-7900), Protein and tRNA interaction (BCM-7002),
Proteins (BCM-2001), Lab of nucleic acids (BCM-3001), Enzymology (BCM-3002), Lab of
proteins and enzymes (BCM-3003)
2) Teaching/research assistant 2004-2009
Can Tho University, Vietnam
- Taught in English General biochemistry (BMB 471) and Biochemistry lab (BMB 471C),
- Taught in French Food biochemistry (CB 344) and general microbiology
- Taught in Vietnamese: Protein and enzymology (BT 306); Lab of Proteins and enzymology
- Traveled to Michigan State University (USA) to work and prepare the courses: Microbial
genome (MMG 433), General biochemistry (BMB 461 and BMB 462) and Biochemistry labs
(BMB 471, BMB 472)
- Traveled to Prince of Songkhla University (Thailand) to study about food biochemistry
- Conducted research on « purification, characterization and recovery of bromelain and papain
from waste pineapple), Funded by VLIR Project, Can Tho university, Vietnam
3) Project manager 2006-2008
Can Tho University, Vietnam
Project: Characterization of fish tra (Pangasius hypophthalmus) proteins and surimi
production, funded by Can Tho University

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4) Assistant-director (part-time) 2007-2009
PVS Company limited, Vietnam
- Organized fieldtrip at fish farms
- Organized company’s product workshops on veterinary, poultry and shrimps: antibiotics,
additives, ponds’ treatment products
- Translated orally, products’ catalogues (English-Vietnamese)
PUBLICATIONS AND COMUNICATIONS
Pham Van Hau, Halim Maroufi, Roger C. Levesque and Jacques Lapointe. Cyclic peptides
identified by phage display are competitive inhibitors of the tRNA-dependent amidotransferase of
Helicobacter pylori. Peptides, 2016. 79: p. 8-15 2016
Pham Van Hau and Soottawat Benjakul. Purification and characterization of trypsin of pyloric ceaca
from big-eye snappers (Priacanthus macracanthus), Journal of Food Biochemistry 30 (2006) 478–495,
Blackwell Publishing 2006
Vo Quoc Van, Pham Van Hau, Ha Thanh Toan. Study on gelatin processing from tra (Pangasius
hypophthalmus) catfish skin, Proceedings: the 1st conference on food science and technology, Mekong
delta, Vietnam, pp. 65-69 2008
Van-Hau Pham, Christian Balg, Sébastien P. Blais, Francois Otis, Normand Voyer, Jacques
Lapointe and Robert Chênevert. Inhibition of Helicobacter pylori Glu-tRNAGln amidotransferase by
two novel analogues of the transamidation transition state, FEBS Letters In preparation
Pham Van Hau, Jacques Lapointe and Jonathan L. Huot. The bacterial heterotrimeric
amidotransferase GatCAB: functions, structures and mechanism-based inhibitors. Minireview, Journal
of biological chemistry. In preparation
Poster: Van-Hau Pham, Christian Balg, Sébastien P. Blais, Jacques Lapointe and Robert
Chênevert. Competitive inhibitors of Helicobacter pylori Asp-tRNAAsn
or Glu-tRNAGln
amidotransferase: the major role of the module analogous to A76 of tRNA. American Society for
microbiology, 113th
General meeting, May 18-21, 2013, Denver, Colorado, USA 2013
Poster: Van-Hau Pham, Halim Maaroufi, Roger C. Lévesque et Jacques Lapointe. Searching for
inhibitors of aminoacyl-tRNA amidotransferase GatCAB of pathogen bacterium Helicobacter pylori.
Research day of engineering and science faculty: Multidisciplinary in sciences and engineering, 3rd
edition, Laval University, Quebec, Canada 2013
Oral presentation: Van-Hau Pham, Jonathan Huot, Robert Chênevert, Roger C. Lévesques and
Jacques Lapointe. Inhibitors of Helicobacter pylori aminoacyl-tRNA amidotransferase (GatCAB) as
lead compounds for a novel antibiotic. 12th
PROTEO annual symposium, pp 17. Sherbrook, Quebec,
Canada. 2012
Oral presentation: Pham Van Hau. Peptide Phage Display: the technique to discover protein-protein
interactions, Institute for system and integrative biology (Interlabs), Laval University 2010

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Oral presentation: Pham Van Hau. Effect of different pH washing solution on the Tra fish protein and
its surimi quality. The 7th
Vietnam-Japan joint seminar, University of science, Vietnam 2009
Oral presentation: Pham Van Hau. Study of fish tra (Pangasius hypophthalmus) surimi prodution by
using alkaline-aided and acid-aided methods. Young scientists’ conferences of sciences and technology,
Thai Nguyen University, Vietnam 2009
SCHOLARSHIPS AND AWARDS
- Oral presentation award from The Quebec Network for Research on Protein Function, Engineering,
and Applications (PROTEO) Sherbrook, Quebec May, 2012
- Young scientist award, Thai Nguyen University, Vietnam March, 2009
- Poster award from the Faculty of Science and Engineering, Laval University March, 2013
- PhD scholarship in biochemistry at Laval University, Canada; offered by Canadian international
development agency 2009-2014
- MSc scholarship offered by University francophone agency (AUF), France 2003-2004
- Outstanding student scholarship, offered by Can Tho University 1999-2003
- French summer course scholarship, France; offered by AUF Jul-Aug 2000
V. SOCIAL ENGAGEMENTS AND INTERESTS
- Performed research in labs and taught in classrooms 2009-2016
- Took part in evaluation and selection for PROTEO’s scholarships (twice) 2012-2013
- Social activities:
- Organized research day of Institute for system and integrative biology (IBIS) 2013
- Parented new foreign students at Laval University 2010
- Cleaned up the Ulaval campus on Green day at Laval University 2012
- Sports:
- Volley-ball a member of volley-ball team, of the Department, Can Tho University 2000-2003
- Ping-pong, 3rd
award of ping-pong competition 2005
- Swimming.
Note: I am a Vietnamese citizen with Canadian permanent resident card in Canada