Initial success rate and predictors of procedural failure in percutaneous coronary intervention on chronic total occlusion (CTO) lesions were investigated. The study found a technical and procedural success rate of 79.2% for percutaneous coronary intervention on CTO lesions using conventional angioplasty wires. No major in-hospital adverse cardiac events occurred. Univariate and multivariate analysis identified smoking as a significant predictor of percutaneous coronary intervention failure, with a odds ratio of 0.16 and p-value of 0.034 for smoking.