Course Syllabus Course Title: Advanced Pathophysiology Course Code: NU621 Credit hours: 3 Prerequisites: NU 500 - Theoretical Foundations for Nursing and NU 560 - Research Methods and Evidence-Based Practice Course Description: The course examines scientific concepts of pathophysiology essential to diagnostic reasoning and clinical management of common disease states. The dilemma of cost and need for laboratory and radiographic evidence to support diagnosis is examined. Program: Graduate Nursing Program Outcomes: 1. Integrate scientific evidence from nursing and biopsychosocial disciplines, genetics, public health, quality improvement, and organizational sciences when designing and implementing outcome measures in diverse settings and through the lifespan. 2. Demonstrate leadership skills that emphasize ethical and critical decision- making, fiscal responsibility, inter-professional relationships that promote safe, quality care within a systems framework. 3. Apply methods, tools, performance measures, and evidence-based standards when evaluating quality indicators within an organizational system. 4. Synthesize theories, models and research findings inherent to nursing practice, education, and management to guide an organization or healthcare system towards achieving successful outcomes. 5. Apply client/patient care technologies and informatics to coordinate and ensure safe quality care and promote effective communication among members of the interprofessional healthcare team. 6. Analyze ethical, legal and sociocultural factors to influence policy development and healthcare delivery systems that promote the health of individuals and populations. 7. Articulate a leadership role within interprofessional teams through effective communication, collaboration and consultation with other professionals to manage, coordinate care and provide safe, quality family- centered and population based care. 8. Incorporate organizational and culturally sensitive client and population centered concepts in the planning, delivery, management and evaluation of direct and indirect evidence-based health promotion care and services to specified individuals, families and populations. 9. Implement scholarly activities in selected individuals, populations, and systems. FNP Program Outcomes: 1. Critical Thinking: Demonstrate critical thinking and holistic caring as an advanced practice nurse. 2. Scientific Literature Analysis: Analyze scientific literature for application to selected diagnosis and treatment plans. 3. Ethical Principles: Synthesize ethical principles into the management and evaluation of healthcare delivery concerns in culturally diverse care settings 4. Competencies: Articulate a personal philosophy and framework acknowledging professional and accrediting agency competencies relating to the role and scope of practice of the family nurse practitioner. 5. Role of FNP: Implement ...

1. Course Syllabus
Course Title: Advanced Pathophysiology
Course Code: NU621
Credit hours: 3
Prerequisites: NU 500 - Theoretical Foundations for Nursing
and NU 560 -
Research Methods and Evidence-Based Practice
Course Description:
The course examines scientific concepts of pathophysiology
essential to
diagnostic reasoning and clinical management of common
disease states. The
dilemma of cost and need for laboratory and radiographic
evidence to support
diagnosis is examined.
Program: Graduate Nursing
Program Outcomes:
1. Integrate scientific evidence from nursing and
biopsychosocial disciplines,

2. genetics, public health, quality improvement, and organizational
sciences
when designing and implementing outcome measures in diverse
settings
and through the lifespan.
2. Demonstrate leadership skills that emphasize ethical and
critical decision-
making, fiscal responsibility, inter-professional relationships
that promote
safe, quality care within a systems framework.
3. Apply methods, tools, performance measures, and evidence-
based
standards when evaluating quality indicators within an
organizational
system.
4. Synthesize theories, models and research findings inherent to
nursing
practice, education, and management to guide an organization or
healthcare system towards achieving successful outcomes.
5. Apply client/patient care technologies and informatics to
coordinate and
ensure safe quality care and promote effective communication
among
members of the interprofessional healthcare team.
6. Analyze ethical, legal and sociocultural factors to influence
policy
development and healthcare delivery systems that promote the
health of
individuals and populations.

3. 7. Articulate a leadership role within interprofessional teams
through
effective communication, collaboration and consultation with
other
professionals to manage, coordinate care and provide safe,
quality family-
centered and population based care.
8. Incorporate organizational and culturally sensitive client and
population
centered concepts in the planning, delivery, management and
evaluation of
direct and indirect evidence-based health promotion care and
services to
specified individuals, families and populations.
9. Implement scholarly activities in selected individuals,
populations, and
systems.
FNP Program Outcomes:
1. Critical Thinking: Demonstrate critical thinking and holistic
caring as an
advanced practice nurse.
2. Scientific Literature Analysis: Analyze scientific literature
for application to
selected diagnosis and treatment plans.
3. Ethical Principles: Synthesize ethical principles into the
management and
evaluation of healthcare delivery concerns in culturally diverse
care settings

4. 4. Competencies: Articulate a personal philosophy and
framework
acknowledging professional and accrediting agency
competencies relating
to the role and scope of practice of the family nurse
practitioner.
5. Role of FNP: Implement the role of the family nurse
practitioner in selected
clinical settings.
Course Learning Objectives:
1. Integrate nursing and related sciences into the delivery of
advanced nursing
care to diverse populations.
2. Incorporate current and emerging genetic/genomic evidence
in providing
advanced nursing care to individuals, families, and communities
while
accounting for patient values and clinical judgment.
3. Compare normal anatomy and physiology to alterations in
function and
regulation of body organs and systems in response to stressors.
Topics & Learning Activities

5. Unit Topics & Activities
Learning
Objective
Supported
Points
Possible
1 THE CARDIOVASCULAR AND LYMPHATIC
SYSTEMS
Topic(s): HTN, CHF, CAD, AOD, MI, Ischemia
Reading:
Chapter 32: Structure and Function of the
Cardiovascular and Lymphatic Systems
Chapter 33: Alterations of Cardiovascular
Function
Chapter 34: Alterations of Cardiovascular
Function in Children
Discussion: Myocardial Infarction
Assignments & Assessments: Unit 1 Quiz
1, 2, 3,

6. 40
60
2 THE PULMONARY SYSTEM
Topic(s): Pulmonary injury, pulmonary
diseases, ARDS, OPD, pneumonia, TB,
pulmonary embolism, pulmonary HTN, Cor
pulmonale, cancer
Reading:
Chapter 35: Structure and Function of the
Pulmonary System
Chapter 36: Alterations of Pulmonary Function
Discussion: COPD
Assignments & Assessments: Unit 2 Quiz
1, 2, 3
40
60
3 THE ENDOCRINE SYSTEM
Topic(s): Thyroid Disorders, Diabetes
Reading:
Chapter 21: Mechanisms of Hormonal
Regulation
Chapter 22: Alterations of Hormonal Regulation
Chapter 23: Obesity and Disorders of Nutrition
Discussion: Hyperthyroidism

7. Assignments & Assessments: Unit 3 Quiz
Endocrine Case Study
1, 2, 3
40
60
100
4 THE DIGESTIVE SYSTEM
Topic(s): Acute and chronic gastritis, duodenal,
gastric, and stress ulcers, ulcerative colitis,
Chron’s disease, hepatitis, IBS, appendicitis,
over and under nutrition, liver dysfunction,
cirrhosis, cholelithiasis with cholecystitis.
Reading:
Chapter 41: Structure and Function of the
Digestive System
Chapter 42: Alterations of Digestive Function
Discussion: Digestive Function
Assignments & Assessments: Unit 4 Quiz
1, 2, 3

8. 40
60
5 THE MUSCULOSKELETAL SYSTEM
Topic(s): Osteoporosis, arthritis, gout,
osteomyelitis
Reading:
Chapter 44: Structure and Function of the
Musculoskeletal System
Chapter 45: Alterations of Musculoskeletal
Function
Discussion: Back Pain
Assignments & Assessments: Unit 5 Quiz
1, 2, 3
40
60
6 THE NEUROLOGIC SYSTEM
Topic(s): Disorders of the spine, stroke
syndromes, headaches

9. Reading:
Chapter 16: Pain, Temperature Regulation,
Sleep, and Sensory Function
Chapter 17: Alterations in Cognitive Systems,
Cerebral Hemodynamics, and Motor Function
Discussions: Neurologic Disorders
Assignments & Assessments: Unit 6 Quiz
Neuro Case Study
1, 2, 3
40
60
100
7 THE RENAL AND UROLOGIC SYSTEMS
Topic(s): UTI, Cystitis, glomerulonephritis,
pyelonephritis, nephrotic syndrome
Reading:
Chapter 38: Structure and Function of the Renal
and Urologic Systems
Chapter 39: Alterations of Renal and Urinary
Tract Function

10. Discussion: Renal Disease
Assignments & Assessments: Unit 7 Quiz
1, 2, 3
40
60
8
Topic(s) Reflection
Discussion: Reflect on Course Objectives
Unit 8 Quiz
40
60
*Pass rates may vary by program requirement- Refer to the
University Catalog
A 90.00% - 100.00%
B 80.00% - 89.99%
F 0.00% - 79.99%

11. Grade Summary
Points
Possible
Weight out
of 1000
pts.
Method of Scoring
Points
Discussion(s) (8) 320 32% Rubric
Quizzes (8) 480 48% Points
Case Studies (2) 200 20% Points
Total 1000 100%
POLICIES
*University policies, such as attendance philosophy,
notification of absences, extenuating
circumstances, accommodation requests, academic dishonesty,
late policy, grading and
grading symbols, and student conduct are included in the
University catalog. Students
should reference the catalog for the complete listing of policies.
*Note: In some cases, program and/or course specific
information may be appended to
the syllabus as an addendum. In these instances, students must

12. consider the syllabus to
be inclusive of any appended information, and as such, students
must adhere to all course
requirements as described in the document in its entirety.