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PROF.NARENDRA MALHOTRA
M.D., F.I.C.O.G., F.I.C.M.C.H, F.R.C.O.G.,F.I.C.S.
• Prof. Dubrovnick International University
• V.P. WAPM(world association of prenatal medicinne)
• President ISAR
• Presiddent Elect ISPAT
• Sec Gen SAFOG
• Member FIGO guidelines committee
• President FOGSI (2008-2009)
• Dean I.C.M.U. (2008)
• Director Ian Donald School of Ultrasound
• National Tech. Advisor for FOGSI-G.O.I.—Mc Arthur Foundation EOC Course
• Managing Director GLOBAL RAINBOW HEALTH CARE
• Director ART-RAINBOW –IVF
• Practicing Obstetrician Gynecologist at Agra. Special Interest in High Risk Obs., Ultrasound, Laparoscopy
and Infertility, ART & Genetics
• Member and Fellow of many Indian and international organisations
• Awarded best paper and best poster at FOGSI : 5 times, Ethicon fellowship, AOFOG young gyn. award,
Corion award, Man of the year award, Best Citizens of India award
• Over 50 published and 200 presented papers
• Over 100 guest lectures given in India & Abroad and 24 ORATIONS
• Organised many workshops, training programmes, travel seminars and conferences
• Editor 18 books, many chapters, on editorial board of many journals
• Editor of series of STEP by STEP books
• Revising editor for Jeatcoate’s Textbook of Gynaecology 7th and 8th edition (2015)
• Very active Sports man, Rotarian and Social worker
MALHOTRA NURSING & MATERNITY HOME PVT. LTD.
GLOBAL RAINBOW HEALTH CARE,AGRA
84, M.G. Road, Agra-282 010
Phone : (O) 0562-2260275/2260276/2260277, (R) 0562-2260279, (M) 98370-33335; Fax : 0562-2265194
HER UNSPOKEN PROBLEMS
Message from PRESIDENT FOGSI
HER UNSPOKEN PROBLEMS
NARENDRA MALHOTRA
MANPREET SHARMA
JAIDEEP MALHOTRA
NEHARIKA MALHOTRA BORA
SHEMI BANSAL
GLOBAL RAINBOW HEALTH CARE AGRA
mnmhagra3@gmail.com
Cosmetic and Asthetic Gynaecology
Common UNSPOKEN problems
• Pelvic organ prolapse—symptomatic /
Asymptomatic
• Urinary dysfunction
• Stress urinary incontinence
• Sexual dysfunction
• Overactive bladder
• Faecal incontinence
• Pelvic pain
• Vulval /vaginal itching and pain
• Abnormal Vaginal discharge
New subspecialities emerging
certified subspeciality……
1. Female Pelvic Medicine
2. Reconstructive Surgery
3. Cosmetic and Asthetic gynaecology
• Vaginal tightening
• Post delivery
rehabilitation
• SUI
• Vaginal dryness
• Vulvar rejuvenation
• Scars
• Vulvodynia/
Vestibulitis
• Lichen sclerosis
• Vaginal infections
• Bleaching
Causes of Tissue Aging &
Laxity
 Genetics
 Menopause
 Low Estrogen States
 Pregnancy & Childbirth
 Smoking
 Obesity
 Significant Weight Fluctuation
Tip of the iceberg
0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
100%
18-24 25-29 30-34 35-39 40-44 45-49 50-54 55-59 60-64 65-69 70-74 75-79 80-84 85-89 >90
Prevalence
Age(years)
pPrevalence by
Aage
Hunskaar S, Lose G, Sykes D, Voss S
The prevalence of urinary incontinence in women in four
European countries
laughing and other stress are more
stress
Stress incontinence
A QOL Problem!
urine leakage
triggered by
coughing,
sneezing,
laughing, lifting,
exercising,
straining
Pads for incontinence – world market
P&G's -incontinence an attractive $7 billion
global
category growing 7% annually.
Compared baby diapers, feminine care products
and tissue
incontinence demonstrates the fastest
growth
Age and Parity
Pelvic floor muscle
denervation and
endopelvic fascial
disruption
Physical activity level
Individual impact is
variable
Types of Urinary Incontinence
 Stress Urinary Incontinence
 Urge Incontinence
 Mixed Incontinence
 Overflow Incontinence
 Atypical Incontinence
Urgency
Frequency
Nocturia / Enuresis
Dysuria
Symptoms of Urinary Incontinence
 Urinary Tract Infection
 Medications
 Abnormal Growths (Polyps, Stones, Cancer)
 Urinary Tract Abnormalities (Fistula, Diverticulum)
 Neuromuscular Problems
 Pelvic Support Problems
Causes of Urinary Incontinence
Understanding pelvic supports
Treatment of Urinary Incontinence
 Lifestyle Changes
 Bladder Training
 Physical Therapy
 Pessary
 Medications
 Bulking Agents
 Surgery
 NEW: Laser Vaginal Rejuvenation
General measures
• Reduce weight
• Stop smoking, treat chronic
cough
• Treat constipation
• Advice regarding pads and
garments
SUI- treatment
• Pelvic floor exercises
• Electrical Stimulation
Conservative
• Implants
• Medications?
• Surgery
Kegel Master ?
• Helps a woman perform proper and effective Keigel
exercises by applying adjustable targeted resistance
against the muscles of the female pelvic floor.
• The Kegelmaster™ has 15 levels of resistance with a
maximum of 4.5lbs of pressure required to close the
unit.
• The Advanced Kegelmaster has 64 levels of
resistance with a maximum of 9.5lbs of pressure
required to close the unit.
20
21
Kegelmaster
Surgery for Stress
Incontinence
Vaginal
Anterior repair
Needle suspension
Slings
MUS
Urethral
Bulking agents
Abdominal
MMK
Colposuspension
Slings
Artificial sphincter
Laparoscopic
Colposuspension
Slings
Colposuspension
Cure rate 60-90%
”Gold standard”???
Complications
• Voiding difficulties (10%)
• De Novo Detrusor
instability (3-15%)
• Prolapse (14%)
Colposuspension Complications
STRESS URINARY INCONTINENCE
minimal invasive surgery
TVT
Ulmsten, 1996
“Integral theory”
Monofilament
Prolene
Midurethral support
No fixation of the
tape
Tension-free vaginal
tape
Cure rate 60 - 90%
Indications
• Primary and failed surgery
• Concomitant prolapse
surgery
Complications
• Bladder perforation
• Retention
• Urgency
Bladder injury at TVT
Bladder perforation rates 2 - 10%
Rates  with previous retropubic
surgery
Remove TVT and site more laterally no
IDC required
Transurethral routePeriurethral route
Urethral
bulking agents
Cure rate 50 –
70%
Temporary
IMPLANTS UNWANTED
EFFECTS
• UTI
• Urinary retention 1.9%
• Urge incontinence 12.6%
(21% did not respond to
anticholinergics)
• Haematuria 5%
Stothers L et al J Urol (1998)
Treatment of Pelvic Prolapse
 Lifestyle Changes
 Bladder Training
 Physical Therapy
 Pessary
 Vaginal Mesh
 Surgery
 NEW: Laser Vaginal Rejuvenation
Surgical Complications
 Surgical Injuries (Organ Damage)
 Voiding Dysfunction
 Bladder Perforation
 Pelvic Visceral Injuries & Hemorrhage
 Mesh Erosion & Extrusion
 Urinary Tract Infections
 Groin Pain
 Dyspareunia
Symptoms of Vaginal Atrophy
 Vaginal Dryness
 Vaginal Burning / Irritation
 Decreased Lubrication During Sexual Activity
 Painful Intercourse
 Vaginal Bleeding or Vulvar Fissures
 Vaginal Discharge
 Pelvic Pressure or Vaginal Bulging
 Urinary Tract Symptoms
 Frequency, Pain, Bleeding or Incontinence
LUBRICANTS
LOCAL ERT
Vaginal dryness/atrophy
Treatments of Vaginal Atrophy
 Hormonal Medications
 Estrogens
 Estrogen Agonist-Antagonist (Osphena)
 Non-Hormonal
 Vaginal Lubricants
 Vaginal Moisturizers
 Regular Sexual Activity
 NEW: Laser Vaginal Rejuvenation
Atrophic Vaginitis
• Pre-pubertal – lactating –
postmenopausal
• Reduced endogenous estrogen
• Causing thinning of the vaginal
epithelium
• Vaginal epithelium susceptible
to trauma and infection
• pH high
pH 5-7 d/t reduction in lactic acid
production and decrease in
lactobacilli decreasing h2o2
Symptoms of Vaginitis
• Abnormal vaginal discharge
• Pruritus
• Irritation
• Burning
• Soreness
• Odor
• Dyspareunia
• Bleeding
• Dysuria
Patient Complaints
• Genital
Dryness/Itching/Burning
Dyspareunia
Vulvar pruritus
Feeling of pressure
Yellow malodorous discharge /leukorrhea
Spotting
Irritation/tear
• Urinary
Dysuria/ Frequency/Hematuria
Urinary tract infection
Stress incontinence
Treatment for Atrophic Vaginitis
• Treated with estrogen replacement (vaginal/oral)
• Oral BCP (ethinyl estradiol up to 50ug)
• Conjugated estrogen up to 1.25mg in combo
w/medroxyprogesterone acetate to prevent
endometrial hyperplasia
• Vaginal cream 1g daily qhs x1m then ½ dose
2X/week (1g vaginal cream=.625mg conjugated
estrogen)
–should give w/ 2.5mg medrxyprogesterone
x14d
• Estrogen vaginal ring (change q3m) (Estring)
delivers 6-9ug estrodiol daily
• Vagifem 1tab intravaginally x2w then 3x/w for 3-6m
VRS – Vaginal Relaxation
Syndrome
it is a quite common
medical condition
described as a loss of
optimal vaginal
structure and is
usually associated
with vaginal delivery
and natural aging..
VRS leads to…….
• Sexual dysfunction
• Urinary incontinence
(Specially stress urinary
incontinence)
• Urogenital syndrome of
menopause
Vestibulodynia
vulvodynia
unexplained pain around introitus
1 million cases per year,all
ages,hypersenstivity to touch
infections and local cause
for unexplained tt very diff
Lichen sclerosus
• Comprises 70% of benign epithelial disorders
→ epithelial thinning, inflammation &
histological changes in the dermis.
• Aetiology: unknown
• Sx: Itching (commonest), vaginal soreness +
Dyspareunia. Burning and pain are uncommon.
• Signs: crinkled skin, L. minora atrophy,
constriction of V. orifice, adhesions,
ecchymoses & fissures.
• Dx: Biopsy is mandatory
• Rx: - emollients, topical steroids.
- Testosterone: not effective than petroleum jelly
& → pruritus, pain & virilization.
- Surgery: avoided unless malignant changes
Lichen Planus
• General Appearance
– Erosive lesions at
vestibule w/without
adhesions resulting in
stenosis
– May have associated oral
mucotaneous lesions and
desquamative vaginitis
– Patient c/o irritating
vaginal , vulvar soreness,
intense burning, pruritus,
and dyspareunia w/post-
coital bleeding
– Types: Papulosquamous
LP/Hypertrophophic LP
/Errosive LP
Treatment
• Intravaginal
hydrocortisone
suppositories BID x 2m
• Steroid creams (medium-
high potency)
• Vaginal estrogen cream if
atrophic epithelium
present
• Vaginal dilators for
stenosis
• Surgery for severe vaginal
synechiae
• Vulvar hygiene
• Emotional support
Vulvar Psoriasis
• Physical Appearance
–Red moist lesions w/without
scales
• Treatment: Topical
corticosteroids
Squamous Cell Hyperplasia
(Atopic Eczema/Neurodermatitis)
 Physical Appearance
 Benign epithelial thickening and
hyperkeratosis
◦ Acute phase with red/moist
lesions
◦ Causing pruritus leading to
rubbing & scratching
◦ Circumscribed, single or
unifocal
◦ Raised white lesions on vulva
or labia majora and clitoris
 Treatment: Sitz baths,
lubricants, oral
antihistamines, Medium
potency topical steroid twice
daily
Lichen Simplex Chronicus
• Physical Appearance
– Thickened white
epithelium on vulva
– Generally unilateral
and localized
• Treatment:
Medium potency
steroid twice daily
prn
Benign Vulval lumps
• Bartholin’s cyst.
• Epidermal inclusion cyst.
• Skene’s duct cyst.
• Congenital mucous cysts: arise from mesonephric ducts remnants.
• Cyst of the canal of Nuck: can give rise to hydrocele in labia maqjora.
• Sebaceous cyst.
• Papillomatosis (solid).
• Fibroma (solid).
• Lipoma (solid).
• Condylomata (solid).
 Cysts are either congenital or arise from obstructed glands.
 Manifestations arise from the cysts (cosmotic) or from infection.
So what NEW can
we offer to HER ?
Non-Invasive Measures
 External Energy Application
 CO2 Laser (with certain settings)
 Er: YAG
 Radiofrequency
 Ultrasound
WHAT IS THERMI Va
• It’s a Non-invasive temperature controlled
radiofrequency device .
• RF energy delivered deeply into vulva ,vagina
• Tissue tightening immediately
• Newer and tighter collagen stimulation – new
softer and smoother skin
THERMI Va
Non – surgical
No anesthesia
Painless
OPD procedure
Immediate results
No pain
Treat outside
(labia)
Treat inside
(vagina)
No downtime
For any age
For loose vagina
For loose labia
For dry vagina
For leaky bladder
For orgasmic
problems
Heating of the skin and mucosa promotes 3 different kinds
of effect:
• Immediate contraction of collagen
• Immediate collagen remodeling and elasticity
• Long term stimulation of production of new collagen
HOW WORKS
HOW WORKS
THERMAL
NEUROGENESIS
increases
blood flow and restores
nerve signaling resulting
in normal vaginal
lubrication.
- Red Alinsod, MD
TREATMENT TIME : what it takes ??
• External labia : 5-10 min, atrophy/lax
• Full vagina : 30 min
• SUI &OAB :10-15min
• Atrophic vaginitis: 10 min
• Cystocele : 7-10 min
• Rectocele : 7-10min
• Orgasmic dysfunction : 15-20 min
NEWER MODALITY
Vaginal Laser Therapy
Clinical Solution For A
Better Feminine Life
HOW ARE
LASERS
DIFFERENT
Alma FemiLift
Key Differentiator: Treatment Time and Efficiency
The Alma FemiLift allows Selective Targeted
Treatment Areas meaning practitioners can
target specific areas or zones 45 degrees at a
time i.e. protocol choosing between 11 o’clock
and 2 o’clock for maximum thermal efficacy and
penetration depth.
ThermiVA
ThermiVA uses a disposable wand to deliver RF
energy to the external and internal vagina. Requires
time to increase temperature into the “therapeutic
range” of 40-45° C. Thermal reaction only, no
ablative reaction reduces long term neocollagenisis.
Requires topical numbing cream for external use
(30-45 min)
3. ThermiVA has a single use probe which times
out after 1 treatment and can’t be reused on the
same patient for treatments 2 & 3. Per patient
costs are $450 vs $120 for Femilift. Femilift has a
much better ROI.
ThermiVA is Monopolar and also requires a
grounding pad. Push downside of “old” mono RF
technology and importance of positioning
grounding pad in the correct spot.
How are we different?
FemiLift Probe
Key Differentiator
ThermiVA Wand
Small shape – can’t be reused – slow
with small spot size
Slim Shape – ease of use. Comfortable
for practitioner and patient.
Femilift™ is an FDA-approved pixel CO2 laser designed and
invented by Alma Lasers™ to treat
vulvo-vaginal dryness,
vaginal laxity
mild to moderate urinary incontinence,
mild prolapse
Vulval diseases
Definition
Rationale for using laser therapy
• 1970
• Late 80s’-90s’
Full field ablation for facial rejuvenation
• 2004
Fractional phothermolysis
• 2009
Vaginal Fractional phothermolysis
• 2014
FDA approves vaginal fractional co2 for:
Skin tightening
Vaginal atrophy
Effect of Laser on
Tissues
Photostimulation
Photodianamic Reaction
Photothermolytic Action
What is Vaginal Laser
• Vaginal Laser Stimulates
Production Of Collagen,
Elastin And Fibroblast
Activity.
• Treat And Improve: Stress
Urinary Incontinence ,
Vaginal Laxity And
Dryness.
Er:YAG laser
• 2940 Nm Wavelength
• Maximum Absorption By
Water
• Minimal Penetration Depth
• Short Thermal Relaxation
Time
• A Short Pulse Width Can
Provide Precise Control With
Minimum Damag
• Can Be Used To Be Ablative In
High Fluence Ranges –Either
Very Superficial Or Very
Aggressive And Deep In Turbo
Mode
Some Satisfied and
Happy customers
contacts:
1. MRS. REENA JAJPURIYA
99260-44117
2. MRS. GARIMA VYAS
98264-23061
3. MRS. NARMADA SEPTA
99934-40608
4. MRS. ANITA JIRATI
83191-85301
5. MRS. NIRMALA GOSWAMI
88899-97235
6. MRS. LALITA PANCHOLIA
99260-71802
6. MRS. JYOTI ARYA
97558-98762
7. MRS. ANJALI DEMBLE
95454-00085
8. MISS. SONAM RAJPUT
96442-21056
9. MRS. BINDU MANDLOI
94259-93231
10. MRS. KANCHAN
ARORRA
88899-78620
11. MRS. TANYA
WADHWANI
89624-76347
Successfully
Completed
INCONTINENCE THERAPY FOR STRESS
URINERY INCONTINENCE = 67
INTIMALASE THERAPY FOR VAGINAL
TIGHTENING = 16
RENOVALASE THERAPY FOR
UROGENITAL SYNDROME = 17
TOTAL THERAPY= 100
Therapy at INDORE centre on
Erb laser INTILASE
What is
• vaginal CO2 laser stimulates production of collagen,
elastin and fibroblast activity.
• Treat and improve: stress urinary incontinence ,
vaginal laxity and dryness.
• Utilizing CO2 Pixel Laser Technology:
Long term thermal effect
Micro ablative effect
Gold standard in Face Treatment & Skin
Tightening
74
The Technology
of FEMILIFT
BEING USED WIDELY IN INDIA BY DEMRA
ABOUT 10 GYNAECS USING FEMILIFT IN INIDA
KOLKATA
BANGLORE
JAIPUR
AGRA
SURAT
DELHI
NASIK
NELLORE
MUMBAI
75
Pixel CO2 laser
Deep Thermal Heating
and Micro-ablation
• Laser energy is delivered to the
vaginal tissue through a DOE -
Diffractive Optical Element
• DOE pixelates the beam to 81
microscopic pixels in a 9x9
pattern
• Pixel pattern promoting faster
healing
• Deep thermal effect for
vaginal collagen remodeling,
without causing aggressive
76
Pixel CO2 laser vs. Scanner
Laser Beam
Pixel Beam Splitter
Split Beams
Focusing Lens
9x9(81Micro Beams)
Directional Mirror
Optical Lens
1 Laser Beam81 Micro Beams
77
Pixel CO2 laser vs. Scanner
1 Laser Beam81 Micro Beams
At the same fluence the
Pixel CO2 is 81 times longer than the
Scanner
30W * T = 100
mj/Pixel
T=100/30
T=3.33 msec
(Pick Power ;
Ablative)
30W/81 Pixel * T =
100 mj/Pixel
T=100*81/30
T=270 msec
Thermal Effect
Treatment Energy 80-120 mj/Pixel
Enhanced thermal effect
78
Pixel CO2 laser
Strong and Impactful
Thermal Effect
• High-powered laser
• Utilization of much higher energy levels by longer
pulse duration
• Microscopic columns of thermal zone penetrates deep
into the submucosa, leaving the surrounding tissue intact,
with minimal ablation
structural support
How does the FemiLift Pixel CO2 Works?
Alma Pixel CO2 surgical laser utilizes fractional technology to
create micro-ablation and thermal damage to the mucosa and sub-mucosa
• fractional laser through holographic lenses
pixelating the beam to 81 microscopic beams (pixels)
• ablated mucosa and microscopic columns
of thermal damage that penetrate deep into the sub-
mucosa
• Strongly stimulates the growth of new collagen
• Collagen remodeling allows tissue re- firming, causing
CO2 Laser
Effective Mechanism
 Thermal Damage
 Superficial Shrinkage
 Deep Asceptic Wound
 Collagen Remodeling
Collagen Remodeling & Stimulation-
Mechanism of Action
Acute Thermal Damage Phase (48-72 hours)
 Edema
 Release of Chemical Mediators
 Collagen Shrinkage
Proliferation Phase (30 days)
 Fibroblastic Recruiting
 New Dermal Molecular Matrix
 New Collagen Fibers
Remodeling Phase (? months)
 Mature Collagen Fibers
 New Elastic Fibers
Beam Splitter – Alma’s CO2 Pixel Solution
• Fractional CO2 combines
micro-ablative approach
with longer pulse for deep
thermal effect
• Allows short, easy and
efficient treatment protocol
reducing procedure time
83
Mechanism of Action
The Action Process Has Three Phases:
Edema
Release of chemical mediators
Shrinkage of collagen and elastic fibers
Early thermal
effect
Phase I
Within 48-72
hr.
Fibroblastic recruiting
New extracellular matrix
New collagen fibers
Proliferation
Phase II
In the
following 30
days
Mature collagen fibers
Increase of collagen fiber strain
Neovascularization: new blood vessel
formation
Improved lubrication, pH (acidity)
Remodelling
Phase III
After 30- 40
days
Physiologic and functional recovery of the vaginal
mucosa.
+ Normal tissue is comprised of a thin
top layer (the epidermis) that rests on a
deeper layer (the dermis). The dermis
contains a matrix of collagen (the basic
building block of skin) and elastin that
provides structure and support to the
vaginal tissue.
Dermis
Epidermis
Elastin Fibers Collagen Fibers
+ Aging and obesity degrades the
vaginal tissue’s normal collagen and
replaces it with abnormal tissue that
does not stretch and recoil. This
creates tissue laxity.
Elastosis
+ CO2 laser removes the abnormal
upper tissue layers, and stimulates
new collagen growth in the dermis
to effectively restructure and restore
it to a state that resembles
undamaged tissue.
New
Collagen
Collagen
Remodeling Process
Vaginal wall coloscopic image immediately post
FemiLift treatment
Micro Ablative Effect
Colposcopic picture of vaginal wall post FemiLift treatment
•
Smooth
treatment
without
damages
or
carbonizat
ion
Immediately post
treatment
Two weeks post
treatment
Histology
histological HE samples
from the time just after the ablative effect (A), the
filling of the
vaporized space" as a column shape (B) at 72-96 h,
the progress of
healing in the vaporized area (C) (D) at 14 and 28
days
respectively, and finally the rejuvenated fascia at two
months (E).
Collagen re-growth 6 months
post FemiLiftTreatment
Before After
89
Histologies
Thick vaginal epithelium, rich in
glycogen
Atrophic vaginal mucosa.
Thin epithelium with mild
parakeratosis
Neovascularizatio
n in the
sub-epithelial,
lamina propria
Courtesy of Jorge Alberto Eias, MD , Buenos Aires,
Argentina
Pre-treatment Post laser treatment Post laser treatment
Menopause: The Journal of The North American Menopause
Society Vol. 22, No. 8
Histological study on the effects of
microablative fractional CO2 laser on
atrophic vaginal tissue: an ex vivo
study
Stefano Salvatore, Umberto Leone Roberti Maggiore,
,Stavros Athanasiou, et al
Advantages
• non invasive procedure
• Office procedure
• “coffee break” procedure -lasting approximately
between 10-20 min
• Easy and safe procedure
• Minimal discomfort and pain
• Effective
• Rapid healing
• Single use and hygienic vaginal
probe
To achieve safe and effective collagen
remodeling for vaginal tissue
rejuvenation, it is important to have
thermal effect and avoid ablative
damage.
FemiLift™ Safety
HOW DOES
FEMILIFT WORKS
Operating the system
FemiLift™
Objectives
 Improving Vaginal Dryness & Pain
 Vaginal Tightening & Improving Sexual Experience
 Treating Mild to Moderate Stress Incontinence
Hygienic Procedure
98
Pixel CO2
Integrating Technology and
Convenience for Optimal Results
• Uses an 10,600 nm CO2
laser
• Power up to 30W/ 70W
• Intuitive, user friendly
interface
• Adaptable to most surgical
microscopes and
colposcopes
FemiLift Single Use Hygienic Vaginal Probe:
Femilift reusable hand-piece with a single-use sheath
All in One, Multi Package
FemiLift Probe FemiLift Slim Probe FemiLift Smart
FemiTight LiteScan FemiCam
Protocol
• Femilift probe
• Apply liquid lidocaine 2% on the
introitus, Waite 3 minutes
• The inner part of the introitus 25 mj/p ,
3 passages
• Outer part of the introitus. 15 mj/p , 3
passages
• Repeat if necessary after one month
Treatment Protocol
103
Vaginal Tightening
• Powerful thermal heating and micro-ablation is
applied to the various layers of the vaginal tissue in a
360 degree pattern
• Vaginal tissues remodelling
The Treatment
Objectives
 Improving Vaginal Dryness & Pain
 Vaginal Tightening & Improving Sexual Experience
 Treating Mild to Moderate Stress Incontinence
Vaginal Wall Tightening
Remodeling tissue throughout the vagina
Collagen Remodeling process
Dermis
Epidermis
Collagen FibersElastin Fibers
+ Normal tissue is comprised of a thin
top layer (the epidermis) that rests on a
deeper layer (the dermis). The dermis
contains a matrix of collagen (the basic
building block of skin) and elastin that
provides structure and support to the
vaginal tissue.
+ Aging and overweight degrades the
vaginal tissue’s normal collagen and
replaces it with abnormal elastic
fibers that do not stretch and recoil.
This creates tissue laxity.
Elastosis
+ Co2 laser removes the abnormal
upper tissue layers, and stimulates
new collagen growth in the dermis
to effectively restructure and restore
it to a state that resembles
undamagedtissue.
New
Collagen
Fractional microablative CO2 laser
for vulvovaginal atrophy in women
treated with chemotherapy and/or
hormonal therapy for breast cancer:
a retrospective study.
Menopause 2016 Oct;23(10):1108-13
Pagano T et al
Fractional microablative CO2 laser treatment is associated
with a significant improvement of VVA symptoms in women
affected by hormone-driven breast cancer.
This procedure has the advantage of relieving
iatrogenic/physiological VVA symptoms without resorting to
contraindicated estrogen preparations, which have been the
most effective therapy thus far.
Urethra Support – can be
achieved with FemiLift
URINE URINE
Normalsupport
under the
muscle
URINARY INCONTINENCE
Loose collagen fibers
NO URINARY INCONTINENCE
Firmed collagen fibers
Loss of support
under the
muscle
The effect of microablative
fractional CO2 laser on
vaginal flora of
postmenopausal women
Climacteric 2016 Oct;19(5):512-8.
Athanasiou S et al
MFCO2-Laser therapy increased Lactobacillus (p < 0.001)
and normal flora (p < 0.001) after the completion of the
therapeutic protocol, which decreased vaginal pH from a
mean of 5.5 ± 0.8 (initial value) to 4.7 ± 0.5 (p < 0.001). The
prevalence of Lactobacillus changed from 30% initially to
79%
110
FemiTight
For Labia Majora Tightening
• Treatments conducted with
this probe use a low fluence
beam laser that gently heats
the tissue
• Effectively restoring and
reviving collagen growth
111
LiteScan
For Labia Majora Rejuvenation
• Char-free tissue ablation with
multiple scanning patterns
• Promotes accelerated re-
epithelization, allowing for faster
healing and tissue regeneration
• Significantly improved overall skin
tone, elasticity and texture, and
reduced superficial pigmentation
112
The System
Our
experienceUSING SINCE 6 MONTHS AGRA
35 SUI CASES
10 VAGINAL TIGHTENING :4 post delivery
5 GENITAL PROLAPSE UNFIT FOR SURGERY
1 WARTS
1 RESHAPING
1 LICHEN LIKE
3 VULVAL VAGINAL ITCHING
2 VAGINAL DRYNESS
ALSO BEING USED BY COSMETIC DEPPT
COLLECTIVE INDIAN EXPERIENCE OF OVER A YEAR WITH OVER 200 CASES OF SUI
Pre-Treatment Consultation
 Complete Health History Questionnaire
 Vaginal / Bladder Questionnaire
 Complete OB/GYN History, Including Pap Smear Results
 Pelvic Exam
Contraindications
 Active HPV / Herpes
 Abnormal Pap Smear
 Active Vaginal Infection
 GYN Cancer
 Undiagnosed Vaginal Bleeding
 Uncontrolled Diabetes
 Pregnancy
 Recent Vaginal Injury
 Any Active Bleeding (Including Menses)
Treatment Protocol
 Office Procedure
 No Anesthesia
 2-3 Passes of Entire Vaginal Canal
 3 Sessions
 1 Month Interval
 1 Memory Session After 1 Year
 May Repeat Full Course After 2 Years
NON GYN USES IN WOMEN
• PREGNANCY STRETCH MARKS
• FACIAL LASER
• WARTS ANYWHERE
• DARK SPOTS AND MOLES
• SCAR MARKS POST C.S. KELOIDS
• EVOLVING INDICATIONS
• OPERATIVE EXTERNAL ALSO WITH CUT LASER
Case 1
• 45 y, G3P2, nurse, patient zero
• Healthy, no operations
• For 2 years pain in the introitus on 12
o'clock. Affect work, avoidance from sex.
trial of various local treatment -failed.
Work up - no infection, normal
colposcopy, diverticula-ruled out
• Started femilift
• Before tx VAS 90, after first tx VAS 60 ,
after second tx VAS 40, after third tx VAS
1/2,resumed sexual activity
VISUAL ANALOG SCORE FOR PAIN SEVERE 75-100 45-74 MODERATE 5-44 MILD 0-4 NO PAIN
Case 2
• 32 y, G1 P1
• Healthy no operation
• Since delivery Vulvodynia , local tx,
behavioral tx, physiotherapy, local
anesthetics - no improvement . Infection-
ruled out, normal colposcopy
• Started femilift
• VAS before tx 10, after one tx 7/8, after
second tx,5 after. Third 3
Case 3
• 36 y G2P2
• Healthy no operations
• 2 years pain during intercourse, siting
• No infection normal colposcopy
• Vas before 9 after one tx 7 after second 4
Case 4
• 28 y G0
• Healthy no operations
• 5 y pain in introitus , no infection, normal
colposcopy
• Trial of various local tx , behavioral tx,
physiotherapy - no improvement refers for
vestibulectomy
• VAS before tx 9, after one tx 3 satisfied
• Vaginal tightening
• Post delivery
rehabilitation
• SUI
• Vaginal dryness
• Vulvar rejuvenation
• Scars
• Vulvodynia/
Vestibulitis
• Lichen sclerosis
• Vaginal infections
• Bleaching
THE NEED IS REAL
THE NEED …NEEDS TO BE RESPECTED
SHE SHOULD DECIDE
ITS HER WHICH MATTERS
WHY SHOULD SHE SUFFER IN SILENCE
Domestic & International
Experience
 87% of patients report significant improvement
in Vaginal Rejuvenation and Tightening
 78% of patients report improvement of Stress
Incontinence
 88% reported complete dryness afterwards
 12% have less leakage afterwards
 22% with insignificant or no improvement
There is no such thing as
PERFECT or COMPLETE…
only continuous improvement.
GIVE H.E.R. WINGS AND LET H.E.R.SOAR
PRACTICE WITH QUALITY,ETHICS AND DIGNITY
FOGSI 2018 IS FOR H.E.R.WITH Q.E.D.
Thank you
Acknowledgements to prof ronen gold,dr ruby ruprai,dr carolyn ,dr vidya pancholy
Dr rashmi chaar khandelwal,dr lila vyas and ALMA lasers
FOR HELPING TO MAKE THIS PRESENTATION AND SHARING DATE AND SLIDES

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Cosmetic and asthetic gynaecology by Dr Narendra Malhotra

  • 1. PROF.NARENDRA MALHOTRA M.D., F.I.C.O.G., F.I.C.M.C.H, F.R.C.O.G.,F.I.C.S. • Prof. Dubrovnick International University • V.P. WAPM(world association of prenatal medicinne) • President ISAR • Presiddent Elect ISPAT • Sec Gen SAFOG • Member FIGO guidelines committee • President FOGSI (2008-2009) • Dean I.C.M.U. (2008) • Director Ian Donald School of Ultrasound • National Tech. Advisor for FOGSI-G.O.I.—Mc Arthur Foundation EOC Course • Managing Director GLOBAL RAINBOW HEALTH CARE • Director ART-RAINBOW –IVF • Practicing Obstetrician Gynecologist at Agra. Special Interest in High Risk Obs., Ultrasound, Laparoscopy and Infertility, ART & Genetics • Member and Fellow of many Indian and international organisations • Awarded best paper and best poster at FOGSI : 5 times, Ethicon fellowship, AOFOG young gyn. award, Corion award, Man of the year award, Best Citizens of India award • Over 50 published and 200 presented papers • Over 100 guest lectures given in India & Abroad and 24 ORATIONS • Organised many workshops, training programmes, travel seminars and conferences • Editor 18 books, many chapters, on editorial board of many journals • Editor of series of STEP by STEP books • Revising editor for Jeatcoate’s Textbook of Gynaecology 7th and 8th edition (2015) • Very active Sports man, Rotarian and Social worker MALHOTRA NURSING & MATERNITY HOME PVT. LTD. GLOBAL RAINBOW HEALTH CARE,AGRA 84, M.G. Road, Agra-282 010 Phone : (O) 0562-2260275/2260276/2260277, (R) 0562-2260279, (M) 98370-33335; Fax : 0562-2265194
  • 4. HER UNSPOKEN PROBLEMS NARENDRA MALHOTRA MANPREET SHARMA JAIDEEP MALHOTRA NEHARIKA MALHOTRA BORA SHEMI BANSAL GLOBAL RAINBOW HEALTH CARE AGRA mnmhagra3@gmail.com Cosmetic and Asthetic Gynaecology
  • 5. Common UNSPOKEN problems • Pelvic organ prolapse—symptomatic / Asymptomatic • Urinary dysfunction • Stress urinary incontinence • Sexual dysfunction • Overactive bladder • Faecal incontinence • Pelvic pain • Vulval /vaginal itching and pain • Abnormal Vaginal discharge
  • 6. New subspecialities emerging certified subspeciality…… 1. Female Pelvic Medicine 2. Reconstructive Surgery 3. Cosmetic and Asthetic gynaecology
  • 7. • Vaginal tightening • Post delivery rehabilitation • SUI • Vaginal dryness • Vulvar rejuvenation • Scars • Vulvodynia/ Vestibulitis • Lichen sclerosis • Vaginal infections • Bleaching
  • 8. Causes of Tissue Aging & Laxity  Genetics  Menopause  Low Estrogen States  Pregnancy & Childbirth  Smoking  Obesity  Significant Weight Fluctuation
  • 9. Tip of the iceberg
  • 10. 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% 18-24 25-29 30-34 35-39 40-44 45-49 50-54 55-59 60-64 65-69 70-74 75-79 80-84 85-89 >90 Prevalence Age(years) pPrevalence by Aage Hunskaar S, Lose G, Sykes D, Voss S The prevalence of urinary incontinence in women in four European countries
  • 11. laughing and other stress are more stress
  • 12. Stress incontinence A QOL Problem! urine leakage triggered by coughing, sneezing, laughing, lifting, exercising, straining Pads for incontinence – world market P&G's -incontinence an attractive $7 billion global category growing 7% annually. Compared baby diapers, feminine care products and tissue incontinence demonstrates the fastest growth Age and Parity Pelvic floor muscle denervation and endopelvic fascial disruption Physical activity level Individual impact is variable
  • 13. Types of Urinary Incontinence  Stress Urinary Incontinence  Urge Incontinence  Mixed Incontinence  Overflow Incontinence  Atypical Incontinence
  • 15.  Urinary Tract Infection  Medications  Abnormal Growths (Polyps, Stones, Cancer)  Urinary Tract Abnormalities (Fistula, Diverticulum)  Neuromuscular Problems  Pelvic Support Problems Causes of Urinary Incontinence
  • 17. Treatment of Urinary Incontinence  Lifestyle Changes  Bladder Training  Physical Therapy  Pessary  Medications  Bulking Agents  Surgery  NEW: Laser Vaginal Rejuvenation
  • 18. General measures • Reduce weight • Stop smoking, treat chronic cough • Treat constipation • Advice regarding pads and garments
  • 19. SUI- treatment • Pelvic floor exercises • Electrical Stimulation Conservative • Implants • Medications? • Surgery
  • 20. Kegel Master ? • Helps a woman perform proper and effective Keigel exercises by applying adjustable targeted resistance against the muscles of the female pelvic floor. • The Kegelmaster™ has 15 levels of resistance with a maximum of 4.5lbs of pressure required to close the unit. • The Advanced Kegelmaster has 64 levels of resistance with a maximum of 9.5lbs of pressure required to close the unit. 20
  • 22. Surgery for Stress Incontinence Vaginal Anterior repair Needle suspension Slings MUS Urethral Bulking agents Abdominal MMK Colposuspension Slings Artificial sphincter Laparoscopic Colposuspension Slings
  • 23. Colposuspension Cure rate 60-90% ”Gold standard”??? Complications • Voiding difficulties (10%) • De Novo Detrusor instability (3-15%) • Prolapse (14%) Colposuspension Complications
  • 24. STRESS URINARY INCONTINENCE minimal invasive surgery TVT Ulmsten, 1996 “Integral theory” Monofilament Prolene Midurethral support No fixation of the tape
  • 25. Tension-free vaginal tape Cure rate 60 - 90% Indications • Primary and failed surgery • Concomitant prolapse surgery Complications • Bladder perforation • Retention • Urgency
  • 26. Bladder injury at TVT Bladder perforation rates 2 - 10% Rates  with previous retropubic surgery Remove TVT and site more laterally no IDC required
  • 27. Transurethral routePeriurethral route Urethral bulking agents Cure rate 50 – 70% Temporary
  • 28. IMPLANTS UNWANTED EFFECTS • UTI • Urinary retention 1.9% • Urge incontinence 12.6% (21% did not respond to anticholinergics) • Haematuria 5% Stothers L et al J Urol (1998)
  • 29.
  • 30. Treatment of Pelvic Prolapse  Lifestyle Changes  Bladder Training  Physical Therapy  Pessary  Vaginal Mesh  Surgery  NEW: Laser Vaginal Rejuvenation
  • 31.
  • 32.
  • 33.
  • 34. Surgical Complications  Surgical Injuries (Organ Damage)  Voiding Dysfunction  Bladder Perforation  Pelvic Visceral Injuries & Hemorrhage  Mesh Erosion & Extrusion  Urinary Tract Infections  Groin Pain  Dyspareunia
  • 35.
  • 36.
  • 37. Symptoms of Vaginal Atrophy  Vaginal Dryness  Vaginal Burning / Irritation  Decreased Lubrication During Sexual Activity  Painful Intercourse  Vaginal Bleeding or Vulvar Fissures  Vaginal Discharge  Pelvic Pressure or Vaginal Bulging  Urinary Tract Symptoms  Frequency, Pain, Bleeding or Incontinence
  • 39. Treatments of Vaginal Atrophy  Hormonal Medications  Estrogens  Estrogen Agonist-Antagonist (Osphena)  Non-Hormonal  Vaginal Lubricants  Vaginal Moisturizers  Regular Sexual Activity  NEW: Laser Vaginal Rejuvenation
  • 40. Atrophic Vaginitis • Pre-pubertal – lactating – postmenopausal • Reduced endogenous estrogen • Causing thinning of the vaginal epithelium • Vaginal epithelium susceptible to trauma and infection • pH high pH 5-7 d/t reduction in lactic acid production and decrease in lactobacilli decreasing h2o2
  • 41. Symptoms of Vaginitis • Abnormal vaginal discharge • Pruritus • Irritation • Burning • Soreness • Odor • Dyspareunia • Bleeding • Dysuria
  • 42. Patient Complaints • Genital Dryness/Itching/Burning Dyspareunia Vulvar pruritus Feeling of pressure Yellow malodorous discharge /leukorrhea Spotting Irritation/tear • Urinary Dysuria/ Frequency/Hematuria Urinary tract infection Stress incontinence
  • 43. Treatment for Atrophic Vaginitis • Treated with estrogen replacement (vaginal/oral) • Oral BCP (ethinyl estradiol up to 50ug) • Conjugated estrogen up to 1.25mg in combo w/medroxyprogesterone acetate to prevent endometrial hyperplasia • Vaginal cream 1g daily qhs x1m then ½ dose 2X/week (1g vaginal cream=.625mg conjugated estrogen) –should give w/ 2.5mg medrxyprogesterone x14d • Estrogen vaginal ring (change q3m) (Estring) delivers 6-9ug estrodiol daily • Vagifem 1tab intravaginally x2w then 3x/w for 3-6m
  • 44. VRS – Vaginal Relaxation Syndrome it is a quite common medical condition described as a loss of optimal vaginal structure and is usually associated with vaginal delivery and natural aging..
  • 45. VRS leads to……. • Sexual dysfunction • Urinary incontinence (Specially stress urinary incontinence) • Urogenital syndrome of menopause
  • 46. Vestibulodynia vulvodynia unexplained pain around introitus 1 million cases per year,all ages,hypersenstivity to touch infections and local cause for unexplained tt very diff
  • 47. Lichen sclerosus • Comprises 70% of benign epithelial disorders → epithelial thinning, inflammation & histological changes in the dermis. • Aetiology: unknown • Sx: Itching (commonest), vaginal soreness + Dyspareunia. Burning and pain are uncommon. • Signs: crinkled skin, L. minora atrophy, constriction of V. orifice, adhesions, ecchymoses & fissures. • Dx: Biopsy is mandatory • Rx: - emollients, topical steroids. - Testosterone: not effective than petroleum jelly & → pruritus, pain & virilization. - Surgery: avoided unless malignant changes
  • 48. Lichen Planus • General Appearance – Erosive lesions at vestibule w/without adhesions resulting in stenosis – May have associated oral mucotaneous lesions and desquamative vaginitis – Patient c/o irritating vaginal , vulvar soreness, intense burning, pruritus, and dyspareunia w/post- coital bleeding – Types: Papulosquamous LP/Hypertrophophic LP /Errosive LP
  • 49. Treatment • Intravaginal hydrocortisone suppositories BID x 2m • Steroid creams (medium- high potency) • Vaginal estrogen cream if atrophic epithelium present • Vaginal dilators for stenosis • Surgery for severe vaginal synechiae • Vulvar hygiene • Emotional support
  • 50. Vulvar Psoriasis • Physical Appearance –Red moist lesions w/without scales • Treatment: Topical corticosteroids
  • 51. Squamous Cell Hyperplasia (Atopic Eczema/Neurodermatitis)  Physical Appearance  Benign epithelial thickening and hyperkeratosis ◦ Acute phase with red/moist lesions ◦ Causing pruritus leading to rubbing & scratching ◦ Circumscribed, single or unifocal ◦ Raised white lesions on vulva or labia majora and clitoris  Treatment: Sitz baths, lubricants, oral antihistamines, Medium potency topical steroid twice daily
  • 52. Lichen Simplex Chronicus • Physical Appearance – Thickened white epithelium on vulva – Generally unilateral and localized • Treatment: Medium potency steroid twice daily prn
  • 53. Benign Vulval lumps • Bartholin’s cyst. • Epidermal inclusion cyst. • Skene’s duct cyst. • Congenital mucous cysts: arise from mesonephric ducts remnants. • Cyst of the canal of Nuck: can give rise to hydrocele in labia maqjora. • Sebaceous cyst. • Papillomatosis (solid). • Fibroma (solid). • Lipoma (solid). • Condylomata (solid).  Cysts are either congenital or arise from obstructed glands.  Manifestations arise from the cysts (cosmotic) or from infection.
  • 54. So what NEW can we offer to HER ?
  • 55. Non-Invasive Measures  External Energy Application  CO2 Laser (with certain settings)  Er: YAG  Radiofrequency  Ultrasound
  • 56. WHAT IS THERMI Va • It’s a Non-invasive temperature controlled radiofrequency device . • RF energy delivered deeply into vulva ,vagina • Tissue tightening immediately • Newer and tighter collagen stimulation – new softer and smoother skin
  • 57. THERMI Va Non – surgical No anesthesia Painless OPD procedure Immediate results
  • 58. No pain Treat outside (labia) Treat inside (vagina) No downtime For any age For loose vagina For loose labia For dry vagina For leaky bladder For orgasmic problems
  • 59. Heating of the skin and mucosa promotes 3 different kinds of effect: • Immediate contraction of collagen • Immediate collagen remodeling and elasticity • Long term stimulation of production of new collagen HOW WORKS
  • 60. HOW WORKS THERMAL NEUROGENESIS increases blood flow and restores nerve signaling resulting in normal vaginal lubrication. - Red Alinsod, MD
  • 61. TREATMENT TIME : what it takes ?? • External labia : 5-10 min, atrophy/lax • Full vagina : 30 min • SUI &OAB :10-15min • Atrophic vaginitis: 10 min • Cystocele : 7-10 min • Rectocele : 7-10min • Orgasmic dysfunction : 15-20 min
  • 62. NEWER MODALITY Vaginal Laser Therapy Clinical Solution For A Better Feminine Life
  • 64. Alma FemiLift Key Differentiator: Treatment Time and Efficiency The Alma FemiLift allows Selective Targeted Treatment Areas meaning practitioners can target specific areas or zones 45 degrees at a time i.e. protocol choosing between 11 o’clock and 2 o’clock for maximum thermal efficacy and penetration depth. ThermiVA ThermiVA uses a disposable wand to deliver RF energy to the external and internal vagina. Requires time to increase temperature into the “therapeutic range” of 40-45° C. Thermal reaction only, no ablative reaction reduces long term neocollagenisis. Requires topical numbing cream for external use (30-45 min)
  • 65. 3. ThermiVA has a single use probe which times out after 1 treatment and can’t be reused on the same patient for treatments 2 & 3. Per patient costs are $450 vs $120 for Femilift. Femilift has a much better ROI. ThermiVA is Monopolar and also requires a grounding pad. Push downside of “old” mono RF technology and importance of positioning grounding pad in the correct spot. How are we different?
  • 66. FemiLift Probe Key Differentiator ThermiVA Wand Small shape – can’t be reused – slow with small spot size Slim Shape – ease of use. Comfortable for practitioner and patient.
  • 67. Femilift™ is an FDA-approved pixel CO2 laser designed and invented by Alma Lasers™ to treat vulvo-vaginal dryness, vaginal laxity mild to moderate urinary incontinence, mild prolapse Vulval diseases Definition
  • 68. Rationale for using laser therapy • 1970 • Late 80s’-90s’ Full field ablation for facial rejuvenation • 2004 Fractional phothermolysis • 2009 Vaginal Fractional phothermolysis • 2014 FDA approves vaginal fractional co2 for: Skin tightening Vaginal atrophy
  • 69. Effect of Laser on Tissues Photostimulation Photodianamic Reaction Photothermolytic Action
  • 70. What is Vaginal Laser • Vaginal Laser Stimulates Production Of Collagen, Elastin And Fibroblast Activity. • Treat And Improve: Stress Urinary Incontinence , Vaginal Laxity And Dryness.
  • 71. Er:YAG laser • 2940 Nm Wavelength • Maximum Absorption By Water • Minimal Penetration Depth • Short Thermal Relaxation Time • A Short Pulse Width Can Provide Precise Control With Minimum Damag • Can Be Used To Be Ablative In High Fluence Ranges –Either Very Superficial Or Very Aggressive And Deep In Turbo Mode
  • 72. Some Satisfied and Happy customers contacts: 1. MRS. REENA JAJPURIYA 99260-44117 2. MRS. GARIMA VYAS 98264-23061 3. MRS. NARMADA SEPTA 99934-40608 4. MRS. ANITA JIRATI 83191-85301 5. MRS. NIRMALA GOSWAMI 88899-97235 6. MRS. LALITA PANCHOLIA 99260-71802 6. MRS. JYOTI ARYA 97558-98762 7. MRS. ANJALI DEMBLE 95454-00085 8. MISS. SONAM RAJPUT 96442-21056 9. MRS. BINDU MANDLOI 94259-93231 10. MRS. KANCHAN ARORRA 88899-78620 11. MRS. TANYA WADHWANI 89624-76347 Successfully Completed INCONTINENCE THERAPY FOR STRESS URINERY INCONTINENCE = 67 INTIMALASE THERAPY FOR VAGINAL TIGHTENING = 16 RENOVALASE THERAPY FOR UROGENITAL SYNDROME = 17 TOTAL THERAPY= 100 Therapy at INDORE centre on Erb laser INTILASE
  • 73. What is • vaginal CO2 laser stimulates production of collagen, elastin and fibroblast activity. • Treat and improve: stress urinary incontinence , vaginal laxity and dryness. • Utilizing CO2 Pixel Laser Technology: Long term thermal effect Micro ablative effect Gold standard in Face Treatment & Skin Tightening
  • 74. 74 The Technology of FEMILIFT BEING USED WIDELY IN INDIA BY DEMRA ABOUT 10 GYNAECS USING FEMILIFT IN INIDA KOLKATA BANGLORE JAIPUR AGRA SURAT DELHI NASIK NELLORE MUMBAI
  • 75. 75 Pixel CO2 laser Deep Thermal Heating and Micro-ablation • Laser energy is delivered to the vaginal tissue through a DOE - Diffractive Optical Element • DOE pixelates the beam to 81 microscopic pixels in a 9x9 pattern • Pixel pattern promoting faster healing • Deep thermal effect for vaginal collagen remodeling, without causing aggressive
  • 76. 76 Pixel CO2 laser vs. Scanner Laser Beam Pixel Beam Splitter Split Beams Focusing Lens 9x9(81Micro Beams) Directional Mirror Optical Lens 1 Laser Beam81 Micro Beams
  • 77. 77 Pixel CO2 laser vs. Scanner 1 Laser Beam81 Micro Beams At the same fluence the Pixel CO2 is 81 times longer than the Scanner 30W * T = 100 mj/Pixel T=100/30 T=3.33 msec (Pick Power ; Ablative) 30W/81 Pixel * T = 100 mj/Pixel T=100*81/30 T=270 msec Thermal Effect Treatment Energy 80-120 mj/Pixel Enhanced thermal effect
  • 78. 78 Pixel CO2 laser Strong and Impactful Thermal Effect • High-powered laser • Utilization of much higher energy levels by longer pulse duration • Microscopic columns of thermal zone penetrates deep into the submucosa, leaving the surrounding tissue intact, with minimal ablation
  • 79. structural support How does the FemiLift Pixel CO2 Works? Alma Pixel CO2 surgical laser utilizes fractional technology to create micro-ablation and thermal damage to the mucosa and sub-mucosa • fractional laser through holographic lenses pixelating the beam to 81 microscopic beams (pixels) • ablated mucosa and microscopic columns of thermal damage that penetrate deep into the sub- mucosa • Strongly stimulates the growth of new collagen • Collagen remodeling allows tissue re- firming, causing CO2 Laser
  • 80. Effective Mechanism  Thermal Damage  Superficial Shrinkage  Deep Asceptic Wound  Collagen Remodeling
  • 81. Collagen Remodeling & Stimulation- Mechanism of Action Acute Thermal Damage Phase (48-72 hours)  Edema  Release of Chemical Mediators  Collagen Shrinkage Proliferation Phase (30 days)  Fibroblastic Recruiting  New Dermal Molecular Matrix  New Collagen Fibers Remodeling Phase (? months)  Mature Collagen Fibers  New Elastic Fibers
  • 82. Beam Splitter – Alma’s CO2 Pixel Solution • Fractional CO2 combines micro-ablative approach with longer pulse for deep thermal effect • Allows short, easy and efficient treatment protocol reducing procedure time
  • 83. 83 Mechanism of Action The Action Process Has Three Phases: Edema Release of chemical mediators Shrinkage of collagen and elastic fibers Early thermal effect Phase I Within 48-72 hr. Fibroblastic recruiting New extracellular matrix New collagen fibers Proliferation Phase II In the following 30 days Mature collagen fibers Increase of collagen fiber strain Neovascularization: new blood vessel formation Improved lubrication, pH (acidity) Remodelling Phase III After 30- 40 days Physiologic and functional recovery of the vaginal mucosa.
  • 84. + Normal tissue is comprised of a thin top layer (the epidermis) that rests on a deeper layer (the dermis). The dermis contains a matrix of collagen (the basic building block of skin) and elastin that provides structure and support to the vaginal tissue. Dermis Epidermis Elastin Fibers Collagen Fibers + Aging and obesity degrades the vaginal tissue’s normal collagen and replaces it with abnormal tissue that does not stretch and recoil. This creates tissue laxity. Elastosis + CO2 laser removes the abnormal upper tissue layers, and stimulates new collagen growth in the dermis to effectively restructure and restore it to a state that resembles undamaged tissue. New Collagen Collagen Remodeling Process
  • 85. Vaginal wall coloscopic image immediately post FemiLift treatment
  • 86. Micro Ablative Effect Colposcopic picture of vaginal wall post FemiLift treatment • Smooth treatment without damages or carbonizat ion Immediately post treatment Two weeks post treatment
  • 87. Histology histological HE samples from the time just after the ablative effect (A), the filling of the vaporized space" as a column shape (B) at 72-96 h, the progress of healing in the vaporized area (C) (D) at 14 and 28 days respectively, and finally the rejuvenated fascia at two months (E).
  • 88. Collagen re-growth 6 months post FemiLiftTreatment Before After
  • 89. 89 Histologies Thick vaginal epithelium, rich in glycogen Atrophic vaginal mucosa. Thin epithelium with mild parakeratosis Neovascularizatio n in the sub-epithelial, lamina propria Courtesy of Jorge Alberto Eias, MD , Buenos Aires, Argentina Pre-treatment Post laser treatment Post laser treatment
  • 90. Menopause: The Journal of The North American Menopause Society Vol. 22, No. 8 Histological study on the effects of microablative fractional CO2 laser on atrophic vaginal tissue: an ex vivo study Stefano Salvatore, Umberto Leone Roberti Maggiore, ,Stavros Athanasiou, et al
  • 91. Advantages • non invasive procedure • Office procedure • “coffee break” procedure -lasting approximately between 10-20 min • Easy and safe procedure • Minimal discomfort and pain • Effective • Rapid healing • Single use and hygienic vaginal probe
  • 92. To achieve safe and effective collagen remodeling for vaginal tissue rejuvenation, it is important to have thermal effect and avoid ablative damage. FemiLift™ Safety
  • 96. Objectives  Improving Vaginal Dryness & Pain  Vaginal Tightening & Improving Sexual Experience  Treating Mild to Moderate Stress Incontinence
  • 98. 98 Pixel CO2 Integrating Technology and Convenience for Optimal Results • Uses an 10,600 nm CO2 laser • Power up to 30W/ 70W • Intuitive, user friendly interface • Adaptable to most surgical microscopes and colposcopes
  • 99. FemiLift Single Use Hygienic Vaginal Probe: Femilift reusable hand-piece with a single-use sheath
  • 100. All in One, Multi Package FemiLift Probe FemiLift Slim Probe FemiLift Smart FemiTight LiteScan FemiCam
  • 101. Protocol • Femilift probe • Apply liquid lidocaine 2% on the introitus, Waite 3 minutes • The inner part of the introitus 25 mj/p , 3 passages • Outer part of the introitus. 15 mj/p , 3 passages • Repeat if necessary after one month
  • 103. 103 Vaginal Tightening • Powerful thermal heating and micro-ablation is applied to the various layers of the vaginal tissue in a 360 degree pattern • Vaginal tissues remodelling The Treatment
  • 104. Objectives  Improving Vaginal Dryness & Pain  Vaginal Tightening & Improving Sexual Experience  Treating Mild to Moderate Stress Incontinence
  • 105. Vaginal Wall Tightening Remodeling tissue throughout the vagina
  • 106. Collagen Remodeling process Dermis Epidermis Collagen FibersElastin Fibers + Normal tissue is comprised of a thin top layer (the epidermis) that rests on a deeper layer (the dermis). The dermis contains a matrix of collagen (the basic building block of skin) and elastin that provides structure and support to the vaginal tissue. + Aging and overweight degrades the vaginal tissue’s normal collagen and replaces it with abnormal elastic fibers that do not stretch and recoil. This creates tissue laxity. Elastosis + Co2 laser removes the abnormal upper tissue layers, and stimulates new collagen growth in the dermis to effectively restructure and restore it to a state that resembles undamagedtissue. New Collagen
  • 107. Fractional microablative CO2 laser for vulvovaginal atrophy in women treated with chemotherapy and/or hormonal therapy for breast cancer: a retrospective study. Menopause 2016 Oct;23(10):1108-13 Pagano T et al Fractional microablative CO2 laser treatment is associated with a significant improvement of VVA symptoms in women affected by hormone-driven breast cancer. This procedure has the advantage of relieving iatrogenic/physiological VVA symptoms without resorting to contraindicated estrogen preparations, which have been the most effective therapy thus far.
  • 108. Urethra Support – can be achieved with FemiLift URINE URINE Normalsupport under the muscle URINARY INCONTINENCE Loose collagen fibers NO URINARY INCONTINENCE Firmed collagen fibers Loss of support under the muscle
  • 109. The effect of microablative fractional CO2 laser on vaginal flora of postmenopausal women Climacteric 2016 Oct;19(5):512-8. Athanasiou S et al MFCO2-Laser therapy increased Lactobacillus (p < 0.001) and normal flora (p < 0.001) after the completion of the therapeutic protocol, which decreased vaginal pH from a mean of 5.5 ± 0.8 (initial value) to 4.7 ± 0.5 (p < 0.001). The prevalence of Lactobacillus changed from 30% initially to 79%
  • 110. 110 FemiTight For Labia Majora Tightening • Treatments conducted with this probe use a low fluence beam laser that gently heats the tissue • Effectively restoring and reviving collagen growth
  • 111. 111 LiteScan For Labia Majora Rejuvenation • Char-free tissue ablation with multiple scanning patterns • Promotes accelerated re- epithelization, allowing for faster healing and tissue regeneration • Significantly improved overall skin tone, elasticity and texture, and reduced superficial pigmentation
  • 112. 112 The System Our experienceUSING SINCE 6 MONTHS AGRA 35 SUI CASES 10 VAGINAL TIGHTENING :4 post delivery 5 GENITAL PROLAPSE UNFIT FOR SURGERY 1 WARTS 1 RESHAPING 1 LICHEN LIKE 3 VULVAL VAGINAL ITCHING 2 VAGINAL DRYNESS ALSO BEING USED BY COSMETIC DEPPT COLLECTIVE INDIAN EXPERIENCE OF OVER A YEAR WITH OVER 200 CASES OF SUI
  • 113. Pre-Treatment Consultation  Complete Health History Questionnaire  Vaginal / Bladder Questionnaire  Complete OB/GYN History, Including Pap Smear Results  Pelvic Exam
  • 114. Contraindications  Active HPV / Herpes  Abnormal Pap Smear  Active Vaginal Infection  GYN Cancer  Undiagnosed Vaginal Bleeding  Uncontrolled Diabetes  Pregnancy  Recent Vaginal Injury  Any Active Bleeding (Including Menses)
  • 115. Treatment Protocol  Office Procedure  No Anesthesia  2-3 Passes of Entire Vaginal Canal  3 Sessions  1 Month Interval  1 Memory Session After 1 Year  May Repeat Full Course After 2 Years
  • 116. NON GYN USES IN WOMEN • PREGNANCY STRETCH MARKS • FACIAL LASER • WARTS ANYWHERE • DARK SPOTS AND MOLES • SCAR MARKS POST C.S. KELOIDS • EVOLVING INDICATIONS • OPERATIVE EXTERNAL ALSO WITH CUT LASER
  • 117. Case 1 • 45 y, G3P2, nurse, patient zero • Healthy, no operations • For 2 years pain in the introitus on 12 o'clock. Affect work, avoidance from sex. trial of various local treatment -failed. Work up - no infection, normal colposcopy, diverticula-ruled out • Started femilift • Before tx VAS 90, after first tx VAS 60 , after second tx VAS 40, after third tx VAS 1/2,resumed sexual activity VISUAL ANALOG SCORE FOR PAIN SEVERE 75-100 45-74 MODERATE 5-44 MILD 0-4 NO PAIN
  • 118. Case 2 • 32 y, G1 P1 • Healthy no operation • Since delivery Vulvodynia , local tx, behavioral tx, physiotherapy, local anesthetics - no improvement . Infection- ruled out, normal colposcopy • Started femilift • VAS before tx 10, after one tx 7/8, after second tx,5 after. Third 3
  • 119. Case 3 • 36 y G2P2 • Healthy no operations • 2 years pain during intercourse, siting • No infection normal colposcopy • Vas before 9 after one tx 7 after second 4
  • 120. Case 4 • 28 y G0 • Healthy no operations • 5 y pain in introitus , no infection, normal colposcopy • Trial of various local tx , behavioral tx, physiotherapy - no improvement refers for vestibulectomy • VAS before tx 9, after one tx 3 satisfied
  • 121. • Vaginal tightening • Post delivery rehabilitation • SUI • Vaginal dryness • Vulvar rejuvenation • Scars • Vulvodynia/ Vestibulitis • Lichen sclerosis • Vaginal infections • Bleaching THE NEED IS REAL THE NEED …NEEDS TO BE RESPECTED SHE SHOULD DECIDE ITS HER WHICH MATTERS WHY SHOULD SHE SUFFER IN SILENCE
  • 122. Domestic & International Experience  87% of patients report significant improvement in Vaginal Rejuvenation and Tightening  78% of patients report improvement of Stress Incontinence  88% reported complete dryness afterwards  12% have less leakage afterwards  22% with insignificant or no improvement
  • 123. There is no such thing as PERFECT or COMPLETE… only continuous improvement. GIVE H.E.R. WINGS AND LET H.E.R.SOAR PRACTICE WITH QUALITY,ETHICS AND DIGNITY
  • 124. FOGSI 2018 IS FOR H.E.R.WITH Q.E.D.
  • 125.
  • 126. Thank you Acknowledgements to prof ronen gold,dr ruby ruprai,dr carolyn ,dr vidya pancholy Dr rashmi chaar khandelwal,dr lila vyas and ALMA lasers FOR HELPING TO MAKE THIS PRESENTATION AND SHARING DATE AND SLIDES