Cordocentesis is performed to evaluate fetal conditions like anemia, infection, and blood disorders. It involves inserting a needle into the umbilical cord under ultrasound guidance between 18-20 weeks of gestation. Complications can include amniotic fluid leakage, drop in heart rate, infection, or blood loss. This study analyzed 92 cordocenteses and found the procedure was successful in diagnosing issues 97.4% of the time. Complications occurred in 2.56% of diagnostic cases and 14% of therapeutic cases. Cordocentesis remains a valuable tool for prenatal diagnosis and treatment of certain conditions despite new genetic techniques.

1. CORDOCENTESIS

2. Umbilical cord

4. Introduction

5. • Evaluation of foetal haemolytic anaemia
• Foetal infection
• Foetal anaemia
• Isoimmunization
Indication

6. Time period
• 18 – 20 week of gestation

7. Requirements
• 22-gauge spinal needle
• 13 cm in length

10. Complication
liking of amniotic
fluid
Drop foetal heart
rate
Infection
Blood loss from
puncture site

11. • The value of cordocentesis in current management of intrauterine
patient
Abstract
OBJECTIVES:
Analyzing the clinical group to evaluate current indications for
cordocenteses, their complications and data obtained in further
pregnancy management.
Rsearch Article

12. • METHODS:
Retrospective analysis evaluated 92 cordocenteses (diagnostic and
therapeutic) performed during the period of 2007‒2018. These were
performed between 17 and 36 weeks of gestation under ultrasound
guidance by a specialist at 2nd Department of Gynecology and
Obstetrics, Faculty of Medicine, Comenius University.
• RESULTS:
Out of 92 procedures, 78 were diagnostic and 14 were therapeutic. The
diagnostic cordocentesis was successful in 97.4 % and intrauterine
therapy was successful in 85.7 %. There were 2 (2.56 %) diagnostic
cordocenteses complicated by fetal demise and 2 (14 %) intrauterine
demises in therapeutic cordocentesis. The pathological karyotype was
detected in 14.5 %. Aneuploidia was present in 4 cases (44.4 %),
mosaicism in 4 cases (44.4 %) and triploidia in one case (11.1 %).

13. • CONCLUSION:
Despite of novel molecular genetic technique cordocentesis still plays
unreplaceable role in current prenatal diagnosis and treatment. The
risk of complications of cordocentesis increases depending on the
severity of fetal pathology in pathologic pregnancies. In some situations
it can be used as a useful tool for original fetal diagnosis and therapy

14. Reference
• Myles textbook for midwives. 16th edition. Elsevier
• Jacob annamma. A comprehensive textbook of midwifery and
gynaecological nursing 4th edition, New dehli; Jay Pee Brothers
Medical publishers (p)Ltd;2015
• Dutta’s D.C Textbook of Obstetrics,6th edition,Published by J.P
Brothers