This document provides a comprehensive list of over 50 publications by Howard Eigen, MD, including journal articles from 1975 to 1992. The publications cover a wide range of topics related to pediatrics and pulmonary medicine, including articles on cystic fibrosis, asthma, congenital lung conditions, and pulmonary function testing in children. Many of the publications involve clinical research studies and evaluations of diagnostic methods and treatment approaches for various respiratory diseases and conditions that affect children.

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Comprehensive List of All Howard Eigen, MD Publications
Journal Articles
Eigen H Croup or Epiglottis: Differential Diagnosis and Treatment Respir Care 1975:20:1158
Eigen H, Lemen R, and Waring WW Congenital Lobar Emphysema: Long Term Evaluation of
Surgically and Conservatively Treated Children Am Rev Respiratory Disease 1976:113(6):823-
831
Georgitis J, Eigen H, Provisor D, and Baehner RL Isolated Pulmonary Leukemic Relapse Following
Successful Bone Marrow Transplant in a Child with Acute Lymphoblastic Leukemia Pediatrics
1979:64(6):913-917
Scott PH and Eigen H Immersion Accidents Involving Pails of Water in the Home J Pediatrics
1980:96(2):282-284
Arasu TS, Franken EA, Wyllie R, Eigen H, Grosfeld JL, Siddiqui AR, and Fitzgerald JF The
Gastroesophageal (GE) Scintiscan in Detection of GE Reflux and Pulmonary Aspiration in
Children Ann-Radiology(Paris) 1980:23(3):187-192
Scott PH and Eigen H: Outpatient Treatment of Asthma in Children; J Indiana State Med
1980:73(4):223-226
Arasu TS, Wyllie R, Fitzgerald JF, Franken EA, Siddiqui AR, Lehman GA, Eigen H and Grosfeld JL
Gastroesophageal Reflux in Infants and Children - Comparative Accuracy of Diagnostic Methods
J Pediatric 1980:96(5):798-803
Dennis JW, Eigen H, Ballantine TV, and Grosfeld JL The Relationship Between Peak Inspiratory
Pressure and Positive End Expiratory Pressure on the Volume of Air Lost Through a
Bronchopleural Fistula J Pediatric Surg 1980:15(6):971-976

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Comprehensive List of All Howard Eigen, MD Publications
Malagonia MA, Ofstein LC, Grosfeld JL, Weber TR, Eigen H, and Baehner RL Survival and
Pulmonary Function Following Chest Wall Resection and Reconstruction in Children J Pediatric
Surg 1980:15(6):906-912
Laughlin JJ, Brady MS and Eigen H Changing Feeding Trends as a Cause of Electrolyte Depletion
in Infants with Cystic Fibrosis Pediatrics 1981:68(2):203-207
Thomas JM, Eigen H and Hodes ME Isozymes Ribonuclease in Human Serum and Urine II A
Survey of Patients With Cystic Fibrosis Clin Chem Acta 1981:111(2-3):199-209
Georgitis J, Eigen H, Warner R and Gonzales MA Oral Theophylline Disposition in Cystic Fibrosis
(CF) Ann Allergy 1982:48(2):175-177
Laughlin J and Eigen H Pulmonary Function Abnormalities in Survivors of Near Drowning J
Pediatric 1982:100(1):26-30
Weber TR, Eigen H, Scott PH, Krishna G and Grosfeld JL Resection of Congenital Tracheal
Stenosis Involving the Carina J Thorac Cardiovasc Surg 1982 :84(2):200-203
Ellis JH, Sequeira FW, Weber TR, Eigen H and Fitzgerald JF Balloon Catheter Occlusion of
Bronchopleural Fistulae Am J Roentgen 1982:138(1):157-159
Eigen H, Laughlin JJ and Homrighausen J Recurrent Pneumonia in Children and its Relationship
to Bronchial Hyperreactivity Pediatrics 1982:70(5):698-704
Givan DC, Scott PH, Eigen H, Grosfeld JL, and Clark JH Achalasia and Tracheal Obstruction in a
Child Eur J Respir Dis 1985:66(1):70-73
Bhat K Scott PH, Eigen H and Boggs PB Evaluation of Lung Sounds by Telephone Ann Allergy
1985:54(2):109-111
Eigen H Clinical Pharmacology of the Wheezing Infant Pediatric Ann 1985:14(4):235-331

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Comprehensive List of All Howard Eigen, MD Publications
Scott PH, Eigen H, Moye LA, Georgitis J and Laughlin JJ Predictability and Consequences of
Spontaneous Extubation in a Pediatric ICU Crit Care Med 1985:13(4):228-232
Eigen H and Wyszomierski D Bleomycin Lung Injury in Children: Pathophysiology and Guidelines
for Management Am J Pediatric Hematol/Oncol 1985:7(l):71-78
Gross K, Desanto A, Grosfeld JL, West KW and Eigen H Intra-abdominal complications of cystic
fibrosis J Pediatric Surg 1985:20(4):431-435
Spiropoulos K, Stevens J, Eigen H, Spiropoulos A Specificity and sensitivity of methacholine
challenge test in children with normal and hyperreactive airways Acta Paediatr Scand
1986:75(5):737-743
Cohen MD, Eigen H, Scott PH, Tepper R, Cory DA, Smith JA and Scales RL Magnetic Resonance
Imaging of Inflammatory Lung Disorders: Preliminary Studies in Children Pediatric Pulmonology
1986:2(4):211-217
Spiropoulos K, Eigen H, Wyszomierski D, et al Methacholine Inhalation Challenge Studies in
Children With Normal and Hyperreactive Airways (Evaluation of the percent decrease in FEV
sub 1 and 2 Gaw) Lotta Tuberc Mal Polm Soc 1986: 56(1):266-274
Cohen MD, Scales RL, Eigen H, Scott P, Tepper R, Cory DA and Smith JA Evaluation of Pulmonary
Parenchymal Disease by Magnetic Resonance Imaging Brit J Radiol 1987:60(711):223-230
Eigen H, Reid JJ, Dahl R, Del Bufalo C, Fasano L, Gunella G, Sahlstrom KK, Alanko KL, Greenbaum
J, Hagelund CH, et al Evaluation of the Addition of Cromolyn Sodium to Bronchodilator
Maintenance Therapy in the Long-term Management of Asthma J Allergy Clin Immunol
1987:Oct:80(4):612-621
Eigen H, Clark NM, and Wolle JM Clinical-Behavior Aspects of Cystic Fibrosis: Directions For
Future Research Am Rev Respir Dis 1987:136(6):1509-1513

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Comprehensive List of All Howard Eigen, MD Publications
Tepper R, Hiatt P, Eigen H, and Smith J Total Respiratory System Compliance in Asymptomatic
Infants with Cystic Fibrosis Am Rev Respir Dis 1987:135(5):1075-1079
Tepper RS, Hiatt PW, Eigen H and Smith J Total Respiratory System Compliance in
Asymptomatic Infants with Cystic Fibrosis Am Rev Repir Dis 1987:135(5):1075-1079
Hiatt P, Eigen H, Yu P, and Tepper RS Bronchodilator Responsiveness in Infants and Young
Children with Cystic Fibrosis Am Rev Respir Dis 1988:137: 119-122
Vane DW, Pritchard J, Colville CW, West KW, Eigen H and Grosfeld JL Bronchoscopy for
Aspirated Foreign Bodies in children Arch Surg 1988:123(7):885-888
Tepper RS, Hiatt P, Eigen H, Scott P, Grosfeld J and Cohen M Infants with Cystic Fibrosis:
Pulmonary Function at Diagnosis Pediatric Pulmonology 1988:5(1):15-18
Stevens JC, Eigen H and Wysomierski D Absence of Long Term Pulmonary Sequelae After Mild
Meconium Aspiration syndrome Pediatric Pulmonology 1988:5(2):74-81
Eigen H, Reid JJ, Dahl R, Del Buffalo C, Fasano L, Gunella G, Sahlstro KK, Alanko KLJ, Greenbaum
J, Hagelund CH, Shapiro GG, Marques RA, Bellia V, Bonsignore G, REsta O, Foschino MP,
Carnimeo N, Granstrom SA, Herrman F et al Evaluation of the Addition of Cromolyn sodium to
Bronchodilator Maintenance Therapy in the Long-term Management of Asthma Folha Med
1988:97(3):195-203
Brooks JG, Eigen H, Boat T, Jobe A, larsen GL, Lemen RJ, Lister G, Loughlin GM, McQuitty JC,
Mellins RB, Platzker A, Taussig LM and Wagener JS Pediatric Pulmonary 1985 Manpower Study
Pediatrics 1988:81(5):680-683
Meyer JL, Ackerman V, Eigen H Sedation with Midazolam Hydrochloride Infusion in Critically Ill
Children Pharmacotherapy 1989:9(3):179
Givan D, Eigen H, Tepper R Longitudinal Evaluation of Pulmonary Function in an Infant
Following Chlorine Gas Exposure, Pediatric Pulmonology, 1989:6(3):191-194

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Comprehensive List of All Howard Eigen, MD Publications
Ackerman V, Hadley K, Eigen H, and Antony V Cystic Fibrosis Tracheobronchial Effluent
Stimulates Proliferation of Lung Fibroblasts in Vitro Chest 1989:95:234S-236S
Scott PH, Kramer WG, Smolensky HM, Harrist RB, Hiatt PW, Baenziger JC, Klank BJ and Eigen H
Day-night Differences in Steady-state Theophylline Pharmacokinetics in Asthmatic Children
Chronobiol Int 1989:6(3):191-4
Tepper RS, Eigen H, Brown J and Hurwitz R Use of Maximal Expiratory Flows to Evaluate Central
Airways Obstruction in Infants Pediatric Pulmonology, 1989:6(4):272-274
Harris JM, Ackerman V and Eigen H Sedation with Midazolam Hydrochloride Infusion in
Critically Ill Children Intens Care Med 1990:16(Suppl 1):S8
Sivan Y, Arce P, Eigen H, Nickerson BG and Newth CJ A Double-Blind, Randomized Study of
Sodium Cromoglycate Versus Placebo in Patients with Cystic Fibrosis and Bronchial
Hyperreactivity J Allergy Clin Immunol 1990:85(3):649-654
Eigen H and Zander J Home Mechanical Ventilation of Pediatric Patients American Thoracic
Society Am Rev Respir Dis 1990:141(1):258-259
Eigen H, Zander J, Lemen RJ, Brooks JG, Chipps BE, Mischler E, Nielson D, and Winnie GB Home
Mechanical Ventilation of Pediatric Patients Am Rev Respir Dis 1990:141(1):258-259
Rosenstein BJ and Eigen H Risks of Alternate-Day Prednisone in Patients with Cystic Fibrosis
Pediatrics 1991:87(2):245-246
Howenstine M, Eigen H and Tepper RS Pulmonary Function In Infants After Pertussis J Pediatric
1991:118:4(1):563-566
Ackerman V, Montgomery G, Eigen H and Tepper R Assessment of Airway Reactivity in Infants
With Cystic Fibrosis Am Rev Resp Dis, 1991:144(2):344-346

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Comprehensive List of All Howard Eigen, MD Publications
Brady MS, Rickard K, Yu P and Eigen H Effectiveness and Safety of Small vs Large Doses of
Enteric Coated Pancreatic Enzymes in Reducing Steatorrhea in Children with Cystic Fibrosis
Pediatric Pulmonology 1991:10(2):79-85
McCarthy LJ, Graves VL, Eigen H, and McGuire WA Platelet apheresis for extreme
thrombocytosis in an 11-year-old girl with CML Transfusion Medicine 1991:1:187-9
Mazer BD, Eigen H, Gelfand EW, Brugman S Remission of Interstitial Lung Disease Following
Therapy of Associated Ulcerative Colitis Pediatric Pulmonology 1993;15(1)55-59
Meltzer EO, Orgel HA, Ellis EF, Eigen H, Hemstreet MPB Long-term Comparison of Three
Combinations of Albuterol, Thoephylline and Beclomethasone in Children with Chronic Asthma
J Allergy Clin Immunol 1992:90:2-11
Tepper RS, Rosenberg D, Eigen E Airway Responsiveness in Infants Following Bronchiolitis
Pediatric Pulmonology 1992:13:6-10
Brady MS, Rickard K, Yu P and Eigen H Effectiveness and Safety of Small vs Large Doses of
Enteric Coated Pancreatic Enzymes in Reducing Steatorrhea in Children with Cystic Fibrosis J Am
Diet Assoc 1992:92(7):813-817
Eigen H Asthma Diagnosis: Getting back to the basics J Respir Dis 1992:13Oct(suppl 10A):S15-
S19
Muller GA, Eigen H Pediatric Pulmonary Function Testing in Asthma Pediatric Clin North Am
1992:39(6):1243-1258
Quittner AL, DiGirolamo AM, Michel M, Eigen H Parental Response to Cystic Fibrosis: A
Contextual Analysis of the Diagnosis Phase Journal of Pediatric Psychology 1992:17(6):683-704

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Comprehensive List of All Howard Eigen, MD Publications
Quittner AL, Opipari LC, Regoli MJ, Jacobsen J, Eigen H The Impact of Caregiving and Role Strain
on Family Life: Comparisons between Mother of Children with Cystic Fibrosis and Matched
Controls Rehabilitation Psychology 1992:37(4);275-290
Mazer BD, Eigen H, Gelfand EW, Brugman, MD Remission of Interstitial Lung Disease Following
Therapy of Associated Ulcerative Colitis 1993:15;55-59
Tepper RS, Montgomery GL, Ackerman V, Eigen H Longitudinal Evaluation of Pulmonary
Function in Infants and Very Young Children with Cystic Fibrosis Pediatric Pulmonology
1993:16;96-100
Tepper RS, Stevens JS, Eigen H Heightened Airway Responsiveness in Normal Female Children
Compared to Normal Female Adults Matched for Size Am J Respir Crit Care Med 1994;149:678-
81
Tepper RS, Rosenberg D, Eigen H, Reister T Bronchodilator Responsiveness in Infants with
Bronchiolitis Pediatrics Pulmonology 1994:17;81-85
Eigen H, Rosenstein BJ, Schidlow DV, FitzSimmons S A Multicenter Trial of Treatment with
Alternate-Day Prednisone in Patients with Cystic Fibrosis J Pediatric 1995:126;515-523
Konig P, Eigen H, Ellis MH, Ellis E, Blake K, Geller D, Shapiro G, Welch M, Scott C The Effect of
Nedocromil Sodium on Childhood Asthma During the Viral Season Am J Respir Crit Care Med
1995;152:1879-1886
Salva PS, Doyle NA, Graham L, Eigen H, Doerschuk CM TNF-, IL-8 Soluble ICAM-1, and
Neutrophils in Sputum of Cystic Fibrosis Patients Pediatric Pulmonology 1996;21:11-19
Wilmott RW, Amin RS, Colin AA, DeVault A, Dozer AJ, Eigen H, Johnson C, Lester LA, McCoy K,
McKean LP, Moss R, Nash ML, Pagel Jue C, Regelmann W, Stokes DC, Fuches HJ Aeorsolized
Recombinant Human Dnase in Hospitalized Cystic Fibrosis Patients with Acute Pulmonary
Exacerbations Am J Respir Crit Care Med 1996:153(6Pt1):1914-1917

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Comprehensive List of All Howard Eigen, MD Publications
Quittner AL, Tolbert VE, Regoli MJ, Orenstein DM, Hollingsworth JL, Eigen H Development of the
Role-Play Inventory of Situations and Coping Strategies (RISCS) for Parent of Children with Cystic
Fibrosis: J Pediatric Psychol 1996;21(2):209-235
Geller DE, Eigen H, Fiel SB, Clark A, Lamarre AP, Johnson CA, Konstan MW for the Dornase Alfa
Nebulizer Group Effect of Smaller Droplet Size of Dornase Alfa on Lung Function in Mild Cystic
Fibrosis Pediatric Pulmonology 1998:25(2):83-87
Quittner AL, Espelage DL, Opipari LC, Carter B, Eid N, Eigen H Role Strain in Couples With and
Without a Child With a Chronic Illness: Associations With Marital Satisfaction, Intimacy, and
Daily Mood Health Psychology 1998;17(2):112-125
Eigen H, The RSV – Asthma Link: The Emerging Story Proceedings of a symposium held in
Washington, DC, November 7, 1998 Sponsored by the American Thoracic Society, Supplement
to The Journal of Pediatrics 1999 Volume 135 Number 2 Part 2
Eigen H, Givan DC Common Pleural Effusions in Children Clinics in Chest Medicine
1998;19(2)June: 363-371
Eigen H. The RSV-asthma link: The emerging story - Proceedings of a symposium held in
Washington, DC, November 7, 1998 - Introduction. Journal of Pediatrics 1999; 135:S1
Howenstine MS, Eigen H; Medical Care of the Adolescent with Asthma; Adolesc Med
2000;11:501-19
McNeils A, Huster G, Michel M, Hollingsworth J, Eigen H, Austin JK Factors Associated With Self-
Concept in Children With Asthma J of Child and Adolescent Psychiatric Nursing 2000:13(2):55-
68
Eigen H, Grant D, Christoph, K, Terrill, D, Heilman DK, Ambrosius WT, Tepper R S, Bieler H:
Spirometric Pulmonary Function in Healthy Preschool Children” Am J Respir Crit Care Med Vol
163pp 619-623, 2001

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Comprehensive List of All Howard Eigen, MD Publications
Eigen H: “Efficacy of Budesonide in Inhaled Corticosteroid-Naïve Patients and Patients with
Asthma”; Clinical Therapeutics, Vol 24, (7) pages 1035-1048, July 2002
Szefler S J, Eigen H: “Budesonide Inhalation Suspension: A Nebulized Corticosteroid for
persistent asthma”; J of Allergy & Clinical Immunology 109(4):729-42, 2002 Apr
Marostica JC, Weist A, Eigen H, Angelicchio C, Christoph K, Savage J, Grant D, Tepper R:
“Spirometry in 3 to 6 year old Children with Cystic Fibrosis”; Am J Respir Crit Care Med Vol 166,
pp 67-71, 2002
Konstan M W, Stern R C, Trout J R, Sherman J M, Eigen H, Wagener J S, Duggan C, Wohl M E,
Colin P: “Ultrase MT12 and Ultrase MT20 In the Treatment of Exocrine Pancreatic Insufficiency
In Cystic Fibrosis: Safety And Efficacy”; Aliment Parmacol Therapy; 20(11-12)1365-1371, 2004
Leflein J, Baker J, Eigen H, Lyzell E, McDermott L: “Safety Features of Budesonide Inhalation
Suspension in the Long-Term Treatment of Asthma in Young Children”; Advances in Therapy;
22(3) May/June, 198-207; 2005
Beydon N, Davis SD, Lombardi E, Allen JL, Arets HG, Aurora P, Eigen H, et al: "Spirometry Centile
charts for young Caucasian Children", Am J Respir Crit Care Med, 175,(12)1304-1345; June 2007
Eigen H, Montgomery GS: "Bronchodilator Response: Another Piece in the Asthma Mosaic", J
Pediatr, 151(5)446-448; November 2007
Eigen H: “Differential Diagnosis & Treatment of Wheezing and Asthma in Young Children”;
Clinical Pediatrics, 47 (8) 735, October 2008
Stanojevic S, Wade A, Cole TJ, Lum S, Custovic A, Silverman M, Eigen H, et al: "Spirometry
Centile Charts for Young Caucasian Children: The Asthma UK Collaborative Initiative"; Am J
Respir Crit Care Med, 180, 547-552; July 2009
Eigen H: "Asthma in Babies"; The Baby Guide, Riley Hospital Publication, October 2009; pg 37

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Comprehensive List of All Howard Eigen, MD Publications
Nitu ME, Eigen H: "Respiratory Failure"; Pediatrics in Review, 30(12):470-477; December 2009
Nitu M, Eigen H: “Every Second Counts: Pediatric advanced airway management is full of
challenges”; Advance for Respiratory Care & Sleep Medicine, 20 (2) 16-18; February 2011
Nitu, M, Montgomery G, Eigen H: “Acid-Base Disorders”; Pediatrics in Review, 32(6)240-250;
June 2011
Nitu M, Eigen H: “Every Second Counts: Pediatric advanced airway management is full of
challenges”; Advance for Respiratory Care & Sleep Medicine, 20 (2) 16-18; February 2011
Ahmed S., McCaskey, M. S., Bringman, S., and Eigen H., 2011, “Catheter-associated bloodstream
infection in the pediatric intensive care unit: A multidisciplinary approach”*: Pediatr.Crit Care
Med: 2012; v13, p e69-e72
Kim Y.J., Hall G.L., Christoph K., Tabbey R., Yu Z., Tepper R.S., and Eigen H.: “Pulmonary Diffusing
Capacity in Healthy Caucasian Children”; Pediatric Pulmonology; 2012, 47(5); 469-475
Ahmed S., McCaskey M.S., Bringman S., and Eigen H.: Catheter associated bloodstream
infection in the pediatric intensive care unit: a multidisciplinary approach: Pediatr. Crit Care
Med, 2012; 13; e69-e72
Loughlin GM, Bostwick S, Cheng TL, Eigen H, Dover GJ; A Proposed Job Description for the
Modern Division Director: Journal of Pediatrics October 2013; 163(4) 932-933
Other Publications
Goodrich T, Eigen H and Wylie P Respiratory Care of the Pediatric Patient (editorial) Respir
Therapy 1980:10(3):12, 92

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Comprehensive List of All Howard Eigen, MD Publications
Eigen H The Clinical Evaluation of Chronic Cough Pediatric Clin North Am 1982:29(1):67-78
Eigen H Treating Asthma Today Bulletin of the American Lung Association 1982:68(1):10
Eigen H Treatment of Choking(Letter) Pediatrics 1983:70(5):300-301
Eigen H Pulmonary Function Testing: A Practical Guide To Its Use in Pediatric Practice Pediatric
in Rev 1986:7(8):235-245
Tepper R, Zander J and Eigen H Chronic Respiratory Problems in Infancy Curr Probl Pediatric
1986:16(6):305-359
Meyer JL, Ackerman V, Eigen H Sedation with Midazolam Hydrochloride Continuous
Intravenous Infusion in Critically Ill Children Clin Res 1988:36(6):896A
Meyer JL, Ackerman V, Eigen H Sedation with Midazolam Hydrochloride continuous Intravenous
Infusion in Critically Ill Children In: Vinik HR, ed Midazolam Infusion of Anesthesia and Intensive
Care Excerpta Medica 1989:67-72
Tepper RS and Eigen H Airway Reactivity in Cystic Fibrosis Clin Rev Allergy, 1991:9(1-2):159-
168
Mueller GA, Eigen H Pulmonary Function Testing in Pediatric Practice Pediatric Rev
1994;15(10):403-412
National Institutes of Health National Heart, Lung and Blood Institute National Asthma
Education and Prevention Program Coordinating Committee Expert Panel Report 2, Guidelines
for the Diagnosis and Management of Asthma NIH Publication No 97-4051, April 1997
Givan DC Eigen H Breathing--what's the "right" answer? Editorial Journal of Pediatrics Dec
1996;129(6):781-782

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Comprehensive List of All Howard Eigen, MD Publications
Eigen H, Weist A Performing PFTs: Pulmonary Function Tests Invaluable in Treatment of Asthma
Advance for Managers of Respiratory Care April 2000;9(4)14-16
Nathanson I, Ramirez-Garnica G, Armatti Wiltrout S: Decreased Attendance at Cystic Fibrosis
Centers by Children Covered by Managed Care Insurance; American Journal of Public Health
Nov, 2005 (95) #11; 1958-1962 (Contributor)
Eigen H, Montgomery G. S.: Bronchodilator Response: Another Piece in the Asthma Mosaic;
(editorial) Journal of Pediatrics Nov 2007; (151):446-448
Abstracts
Eigen H, Lemen R and Waring WW Pulmonary function in children with surgically treated and
untreated congenital lobar emphysema Paper presented at American Thoracic Society Annual
Meeting, Montreal, May 21, 1975 Am Rev Resp Dis 1975:3(6):935
Menendez-Cordova R, Wegmann M, Eigen H, Lemen R, Waring WW and Diem J Ventilatory
response to carbon dioxide (CO2): Comparison between successive single day and consecutive
daily trials in normal adults Clinical Research 1976:14(1):33A
Karlson KH, Eigen H, Lemen RJ and Waring WW Pulmonary function during recovery from near
drowning Pediatric Research 1976:10:462
Menendez-Cordova R, Wegmann M, Eigen H, Lemen R, Waring WW and Diem J Intraindividual
variability of the ventilatory response to CO2 rebreathing Paper presented to American Thoracic
Society on May 18, 1976 Am Rev Resp Dis 1976:113:213
Coates TD, Eigen H, Ballantine RVN, Richard KA, Grosfeld JL and Baehner RL Increased risk of
pulmonary embolus in children receiving central hyperalimentation Pediatric Research
1978:10:432

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Comprehensive List of All Howard Eigen, MD Publications
Thirunavukkarasu S, Wyllie R, Eigen H, Grosfeld JL, Siddiqui AR, Franken EA, Lehman GA and
Fitzgerald JF A comparison of clinical measurements of Gastroesophageal reflux (GER) in
infants and children Gastroenterology 1979:76:1261
Menendez R, DeSalazar W, Georgitis J, Eigen H, and Waring WW Site of exercise induced airway
reactivity in cystic fibrosis (CF) Am Rev Resp Dis 1979:119(supp):276
Georgitis J, Eigen H, Glick M, Warner R and Gonzalez M Theophylline absorption in cystic
fibrosis (CF) Am Rev Resp Dis 1979:119(supp):276
Thirunvukkarasu S, Franken EA, Wyllie R, Eigen H, Grosfeld JL, Siddiqui AR and Fitzgerald JF
Diagnostic value of gastro-esophageal scintiscan in detection of Gastroesophageal reflux and
pulmonary aspiration Presented at the Sixteenth Congress-European Society of Pediatric
Radiology, Cologne, West Germany, May 4, 1979
Thirunvukkarasu S, Siddiqui AR, Wyllie R, Eigen H Franken EA, Wellman HN, Grosfeld JL and
Fitzgerald JF Usefulness of radionuclide studies in detection of Gastroesophageal reflex and
pulmonary aspiration in children Presented at the Society of Nuclear Medicine 26th Annual
Meeting, Atlanta, Georgia, June 29, 1979
Scott PH, Eigen H, Moye L, Georgitis J and Laughlin J Spontaneous endotracheal extubation in a
Pediatric intensive care unit (PICU) Am Rev Resp Dis 1980:121(4):301
Sanders SW, Warner RN, Georgitis J, Eigen H and Gonzalez M Deschlorpheniramine disposition
in man Presented at meeting of Academy of Pharmaceutical Sciences, Washington, DC, April 24,
1980
Thomas JM, Eigen H and Hodes ME Ribonuclease isozymes in serum and urine from cystic
fibrosis patients Presented at the CF Club Annual Meeting, San Antonio, Texas, April 29, 1980
CF Club Abstracts 1980
Dennis JW, Eigen H, Ballantine TVN and Grosfeld JL The relationship between peak inspiratory
pressure and end expiratory pressure on the volume of air lost through a bronchopleural fistula

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Comprehensive List of All Howard Eigen, MD Publications
Presented at meeting of the American Pediatric Surgical Association, Marco Island, Florida, May
8, 1980
Malangoni MA, Ofstein LC, Grosfeld JL, Weber TR, Eigen H and Baehner RL Survival and
pulmonary function following chest wall resection and reconstruction in children Presented at
meeting of the American Pediatric Surgical Association, Marco Island, Florida, May 8, 1980
Eigen H, Laughlin JJ and Homrighausen J Recurrent pneumonia as the presenting manifestation
of asthma in children Presented at the 46th Annual Scientific Assembly of the American College
of Chest Physicians, Boston, Massachusetts, October 26 - 30, 1980 Chest 1980:78(3)515
Eigen H, Laughlin J, Glick M, Scott P and Gonzalez M Decreased sensitivity to methacholine in
cystic fibrosis patients treated with theophylline Presented at meeting of American Federation
for Clinical Research Midwest Section, November 6, 1980 Clinical Research 1980:28(4):743A
Laughlin J and Eigen H Pulmonary function abnormalities in children following near drowning
accidents Presented to American Review of Respiratory Disease at the American Thoracic
Society, May 11, 1981
Givan D, Scott P, Jeglum E and Eigen H Lung function and airway reactivity of children 3 to 10
years after foreign body aspiration Presented to American Review of Respiratory Disease at
American Thoracic Society, May 11, 1981 Am Rev Resp Dis 1981:123(supp):158
Stevens JC, Eigen H and Jeglum E Bronchodilation from deep inspiration causing false negative
Presented at the American Lung Association Annual meeting, Miami Beach, Florida, May 19 - 25,
1984 Am Rev Resp Dis 1984:129(4)
Scott P, Smolensky M, Harrist R, Kramer W, Hiatt P, Baenziger J, Klank B and Eigen H (sponsored
by Schreiner R) Circadian variation of theophylline (T) pharmacokinetics in asthmatic children
Presented at the annual combined meeting of the American Pediatric Society and the Society for
Pediatric Research, San Francisco, California, May 3, 1984, Pediatric Research
1984:18(supp):404A

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Comprehensive List of All Howard Eigen, MD Publications
Klank B and Eigen H: Circadian rhythms in steady-state theophylline pharmacokinetics in
children Presented at The First International Montreux Conference of Chronopharmacology,
Montreux, Switzerland, March 27, 1984 In: Reinberg A and Smolensky M, eds Biological
Rhythms and Medications: Proceedings of The First International Montreux Conference of
Chronopharmacology, Montreux, Switzerland, March 26 - 30, 1984 Oxford: Pergamon Press,
1984
Scott P, Harrist R, Smolensky M, Kramer W, Hiatt P, Baenziger J, Klank B and Eigen H: The effect
of sustained-release theophylline on the circadian variation of pulmonary function in Pediatric
patients Presented at The First International Montreux Conference of Chronopharmacology,
Montreux, Switzerland, March 27, 1984 In: Reinberg A and Smolensky M, eds Biological
Rhythms and Medications: Proceedings of The First International Montreux Conference of
Chronopharmacology, Montreux, Switzerland, March 26 - 30, 1984 Oxford: Pergamon Press,
1984
Stevens J, Scott P, Eigen H and Hearn D Effect of inspired water vapor on pulmonary function in
cystic fibrosis Presented at the annual meeting of the American College of Chest Physicians,
Dallas, Texas, October 10, 1984 Chest 1984:86:311
Hiatt P, Tepper R and Eigen: Bronchodilator response in infants with cystic fibrosis Am Rev Resp
Dis 1985:131(4)(supp):A240
Tepper R, Hiatt P and Eigen H: Total respiratory system compliance in infants with cystic fibrosis
Am Rev Resp Dis 1985:131(4)(supp):A240
Tepper R, Hiatt P, Eigen H, Wyszomierski D and Meyers J Flow limitation in infants with cystic
fibrosis during a pulmonary exacerbation Am Rev Resp Dis 1985:131(4)(supp):A240
Scott P, Klank B, Hiatt P, Kramer W, Baenziger J, Smolensky M and Eigen H: Computer Assisted
determination of theophylline (T) doses: the effect of circadian rhythms of T pharmacokinetics
Am Rev Resp Dis 1985:131(4)(supp):A269
Stevens J, Eigen H, Wyszomierski D, Spiropoulos K, Scott P, Tepper R and Jeglum E Bronchial
reactivity in normal children: a subgroup with positive methacholine challenge Poster presented

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Comprehensive List of All Howard Eigen, MD Publications
at the annual meeting of the American Thoracic Society, Anaheim, California, May 13, 1985 Am
Rev Resp Dis 1985:131(4) (supp):A235
Spiropoulos K, Eigen H, Wyszomierski D, Stevens J and Scott P Meconium aspiration syndrome:
an absence of pulmonary sequelae Presented at the annual meeting of the American Thoracic
Society, Anaheim, California, May 13, 1985
Hiatt P, Scott P, Hearn D, Kramer W, Smolensky M, Harrist R, Klank B, Banziger J and Eigen H
Effect of dosing time on pharmacokinetics of once daily theophylline in asthmatic children
Presented at the annual meeting of the American Thoracic Society, Anaheim, California, May 13,
1985
Hiatt P, Tepper R, and Eigen H Factors effecting respiratory function in infants with cystic
fibrosis Pediatric Research 1986:20(4)(supp):473A
Brady MS, Rickard KA, Yu P, and Eigen H Effectiveness and safety of low vs high doses of enteric
coated pancreatic enzymes (EC) in reducing steatorrhea in cystic fibrosis (CF) children Presented
at 71st Annual Meeting of the Federation of American Societies for Experimental Biology,
Washington DC, March 29 - April 2, 1987
Ackerman V, Tepper R, Eigen H, Brady S, Scott P, Grosfeld J and Meyers J Longitudinal
evaluation of lung function of cystic fibrosis infants: Relationship to presenting symptoms and
nutritional status Am Rev Resp Dis 1987:135:A285
Ackerman V, Tepper R, Eigen H, Clark J and West K A positive bronchodilator response in infants
with Gastroesophageal reflux Am Rev Resp Dis 1987:135:A381
Howenstine M, Tepper R, Ackerman V, Eigen H and Kleiman M Airway hyperreactivity in infants
following pertussis infection Am Rev Resp Dis 1987:135:A382
Ackerman V Eigen H and Newth C A positive outcome of mechanical ventilation in young cystic
fibrosis patients with acute respiratory compromise Ped Pulmonology 1987: Supplement 1:94

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Comprehensive List of All Howard Eigen, MD Publications
Ackerman V, Long V, Hui C, Eigen H and Tepper R Evaluation of pulmonary function in twin
infants Am Rev Resp Dis 1988:137
Ackerman V, Montgomery G, Eigen H and Tepper R Airway reactivity in cystic fibrosis infants
Am Rev Resp Dis 1988:137
Ackerman V, Hadley K, Eigen H and Antony V Cystic fibrosis tracheobronchial effluent
stimulates proliferation of lung fibroblasts in vitro Aspen Lung Conference, June 19, 1988
Ackerman V, Montgomery G, Eigen H and Tepper R Use of ultrasonically nebulized distilled
water to evaluate airway reactivity in cystic fibrosis infants Ped Pulmonology 1988:Supplement
2:129
Tepper R, Ackerman V and Eigen H Changes in lung function during hospitalization and at
follow-up in cystic fibrosis infants Pediatric Pulmonology 1988: Supplement 2:128
Ackerman V, Hurwitz R, Brown J Eigen H and Tepper R Abnormal pulmonary function in infants
with vascular rings: Pre and post-op evaluation Midwest Society for Pediatric Research,
November 10, 1988
Meyer J Ackerman V and Eigen H Sedation with midazolam hydrochloride continuous infusion
in critically ill children Midwest Society for Pediatric Research, November 11, 1988
Meyer JL, Ackerman V, Eigen H, (intro by R Hurwitz) Sedation with hydrochloride continuous
intravenous infusion in critically ill children Presented to Midwest Society for Pediatric Research
subsection meeting, Chicago IL, November 18, 1988
Meyer JL, Ackerman V, Eigen H Sedation with midazolam hydrocloride infusion in critically ill
children American College of Clinical Pharmacy Tenth Annual Meeting, Kansas City, MO, August
6-9, 1989

18. 18
Comprehensive List of All Howard Eigen, MD Publications
Meltzer EO, Ellis EF, Eigen H and Hemstreet MP Comparison of 3 combinations of albuterol (A),
theophylline (T) and beclomethasone (B) in children with asthma American Academy of Allergy
and Immunology (submitted)
Harris JL, Ackerman V, and Eigen H Sedation with hydrochloride continuous intravenous
infusion in critically ill children Presented at the 5th European Congress on Intensive Care
Medicine, Amsterdam, The Netherlands, June 5, 1990
Quittner A, DiGirolama A, Michel M and Eigen H The impact of the diagnosis phase: parenting
stress, marital satisfaction, and emotional adjustment Accepted by the Fourth Annual North
American & 1990 International CF Conference
Rosenberg D, Tsangaris M, Eigen H and Tepper R Outpatient bronchiolitis -longitudinal
evaluation Am Rev Respir Dis 1989:139(4):part 2, A65
Stevens J, Eigen H and Tepper R Bronchial responsiveness in airway caliber matched normal
Pediatric and adult females Presented to American Thoracic Society 1990 World Conference on
Lung Health, Boston, MA, May, 1990
Tepper R, Rosenberg D and Eigen H Bronchodilator response in infants with bronchiolitis
Presented to American Thoracic Society 1990 World Conference on Lung Health, Boston, MA,
May, 1990
Slater NF, Green M, Eigen H, Hui S and Taylor HG Effects of Theophylline on behavior in children
with chronic asthma Presented to American Pediatric Society, Society for Pediatric Research
April 1991
Quittner A, Digirolamo A, Jacobsen J and Eigen H A Contextual model of parenting problems
and outcomes for newly diagnosed families Presented to the Fifth Annual North American CF
Conference, Dallas, TX, October, 1991
Eigen H, Konig P, Ellis M, Ellis E, Geller D, Shapiro G, Welch M Effect of Nedocromil Sodium on
Symptomatic Respiratory Infection (SRI-)-Induced Asthma Exacerbations Presented to the 12 th
Asia Pacific Congress on Diseases of the Chest, Seoul, Korea, September 30 - October 13, 1992

19. 19
Comprehensive List of All Howard Eigen, MD Publications
Salva PS, Eigen H, Doerschuk CM TNF- L-8 and s ICAM-1 Concentrations in the Sputum of
Patients with Cystic Fibrosis (Submitted to the ATS 1994 Annual Meeting)
Salva PS, Eigen H, Doerschuk CM A longitudinal study of TNF- -1 in the sputum of
patients with cystic fibrosis (Submitted to the Cystic Fibrosis Foundation 1994 Annual Meeting )
Tepper RS, Eigen H, Stevens J, Angelicchio C, Kisling J Corticosteroid Treatment for Cystic
Fibrosis Infants Hospitalized for Lower Respiratory Illness Eur Respir J 1997;9:175S,#1133
Geller DE, Eigen H, Stanley FB, Clark A, Lamarre AP, Johnson CA, Konstand MW Effect of Smaller
Droplet Size of Dornase Alfa on Lung Function in Mild Cystic Fibrosis Presented Twelfth
International Cystic Fibrosis Congress, Jerusalem, Israel June 16-21, 1996 and the Tenth Annual
North American Cystic Fibrosis Conference, Orlando, Florida, October 24-27, 1996
Canani S, Eigen H, Blagburn M, Terrill D A Comparison of Flutter Valve with Percussion in Stable
Cystic Fibrosis Patients (presented 1997 Annual ATS Meeting)
Tepper RS, Eigen H, Stevens J, Angelicchio C, Kisling J, Ambrosius W, Heilman D Lower
Respiratory Illness in Infants and Young Children with Cystic Fibrosis: Evaluation of Treatment
with Intravenous Hydrocortisone Pediatric Pulmonology 1997;24:48-51
Lai HC, Kosorok Mr, FitzSimmons SC, Rosenstein BJ, Campbell PW, Eigen, H, Farrell PM Long-
Term Growth Evaluation in Children With Cystic Fibrosis With History Of Regular Use Of
Alternate-Day Prednisone Therapy 13th Annual North American CF Conference Abstract ID
#505
Books
Eigen H: Contributions to section on pulmonary diseases In: Waring WW and Jeansonne L, eds
Practical Manual of Pediatrics St Louis: CV Mosby Company, 1975

20. 20
Comprehensive List of All Howard Eigen, MD Publications
Eigen H and Waring WW Tracheostomy care In: Shirkey HC, ed Pediatric Therapy, 5th ed St
Louis: CV Mosby Company, 1975
Eigen H: Tracheostomy care In: Shirkey HC, ed Pediatric Therapy, 6th ed St Louis: CV Mosby
Company, 1980
Kramer WG, Scott PH, Smolensky MH, Harrist R, Hiatt P, Baenziger J, Klank B and Eigen H:
Circadian rhythms in steady-state theophylline pharmacokinetics in children In: Reinberg A,
Smolensky M and Labrecque G, eds Biological Rhythms and Medications: Proceedings of The
First International Montreux Conference of Chronopharmacology, Montreux, Switzerland,
March 26 - 30, 1984 Oxford: Pergamon Press, 1984:77-80
Scott P, Harrist R, Smolensky M, Kramer W, Hiatt P, Baenziger J, Klank B and Eigen H: The effect
of sustained-release theophylline on the circadian variation of pulmonary function in Pediatric
patients In: Reinberg A, Smolensky M and Labrecque G, eds Biological Rhythms and
Medications: Proceedings of The First International Montreux Conference of
Chronopharmacology, Montreux, Switzerland, March 26 - 30, 1984 Oxford: Pergamon press,
1984:89-92
Eigen H: Interpretation of lung function in children In: Conrad SA, Kinasewitz GT and George
RB, eds Pulmonary Function testing: Principles and Practice New York: Churchill Livingstone
Inc, 1984:225-249
Eigen H and Scott P Asthma In: Green M and Haggerty RJ, eds Ambulatory Pediatrics III
Philadelphia: WB Saunders, 1984
Eigen H Allergic rhinitis In: Green M and Haggerty RJ, eds Ambulatory Pediatrics III
Philadelphia: WB Saunders, 1984
Eigen H International multicenter trial of cromolyn sodium in children with asthma In: Murphy
S, McFadden ER, Eigen H, Spector SL and Selcow JE, eds Managing Asthma in the 80's
(Highlights of a 14-city videoconference) Princeton: Excerpta Medica, 1986:9-12
Eigen H and Hsu KHK Pulmonary function testing Columbus: Ross Laboratories, 1986

21. 21
Comprehensive List of All Howard Eigen, MD Publications
Eigen H and McWilliams B The life threatening asthma attack in children In: Jenne JW and
Murphy S, eds Bronchodilators: Theory and Practice Marcel Dekker, Inc, New York/Basel,
1987:869-896
Eigen H and Grosfeld J Pulmonary Physiology in the Surgical Infant In: Othersen HB, ed The
Pediatric Airway Philadelphia: WB Saunders, 1991
Eigen H and Stevens, J Chronic Cough in Children In: Conn, R, ed Current Diagnosis 8
Philadelphia, WB Saunders, 1991
Eigen H and Gergerding, K Ventilation Perfusion Inequality In: Fuhrman BP, Zimmerman JJ, eds
Pediatric Critical Care St Louis: Mosby Year Book, 1992:395-398
Westenkirchner D, Eigen H Maturation of the Respiratory System In: Holbrook PR, ed Textbook
of Pediatric Critical Care Philadelphia: W B Saunders, 1992:413-422
Eigen H, Gerberding KM Lower Airway Disease In: Holbrook PR, ed Textbook of Pediatric
Critical Care Philadelphia: W B Saunders, 1992:517-522
Loughlin, GM, Eigen H Co-editors Respiratory Disease in Children: Diagnosis and Management
Baltimore: Williams & Wilkins, 1994
Accurso FJ, Eigen H, Loughlin GM In: Loughlin GM, Eigen H, eds Respiratory Disease in
Children: Diagnosis and Management Baltimore: Williams & Wilkins, 1994:67-76
Eigen H Lung Function Testing In: Loughlin GM, Eigen H, eds Respiratory Disease in Children:
Diagnosis and Management Baltimore: Williams & Wilkins, 1994:77-86
Eigen H Chronic/Recurrent Pulmonary Infiltrates In: Loughlin GM, Eigen H, eds Respiratory
Disease in Children: Diagnosis and Management Baltimore: Williams & Wilkins, 1994:215-222

22. 22
Comprehensive List of All Howard Eigen, MD Publications
Eigen H Respiratory Disorders, Section Editor In: Finberg L, ed Saunders Manual of Pediatric
Practice Philadelphia: WB Saunders, 1998:618-679
Eigen H Critical Respiratory Disease In: Finberg L, ed Saunders Manual of Pediatric Practice
Philadelphia: WB Saunders, 1998:666-667
Eigen H Bronchiolitis In: Finberg L, ed Saunders Manual of Pediatric Practice Philadelphia: WB
Saunders, 1998:632-633
Eigen H Blood Gas Analysis In: Finberg L, ed Saunders Manual of Pediatric Practice
Philadelphia: WB Saunders, 1998: 673-674
Eigen H Pulmonary Hemosiderosis In: Finberg L, ed Saunders Manual of Pediatric Practice
Philadelphia: WB Saunders, 1998:656
Eigen H Stridor In: Finberg L, ed Saunders Manual of Pediatric Practice Philadelphia: WB
Saunders, 1998:621-622
Eigen H, Macke J Ventilation Perfusion Inequality In Fuhrman BP, Zimmerman JJ, eds Pediatric
Critical Care, 2nd
Ed St Louis: Mosby, 1998:400-408
Ackerman VL, Eigen H Lower Airway Disease, In Fuhrman BP, Zimmerman JJ, eds Pediatric
Critical Care, 2nd
Ed St Louis: Mosby, 1998:472-476
Eigen H Pulmonary Function Testing In: Murphy S, Kelly HW, eds Pediatric Asthma New York:
Marcel Decker, 1999: 133-150
Stevens JC, Eigen H Cough In: Rakel R, ed Conn’s Current Therapy, 2000:22-25
Ackerman V, Rotta A, Eigen H: Asthma In Pediatric Critical Care, CV Mosby Company, 2011