2. Dysfunction of
Either cerebral hemispheres or
Midbrain tegmentum
▪ Reticular activating system
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3. Function
Maintains the cerebral cortex in a state of
wakeful consciousness
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4. Upper brainstem
Medial thalamus
Very close to area concerned with pupillary
function and eye movements
Pupillary enlargement
Loss of movements of the eyes
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5. Reticular activating system
Ascending projections to the cortex
Cortex
Corticothalamic connections
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6. 75 mL per 100 g/min in gray matter
30 mL per 100 g/min in white matter
Mean
55 mL per 100 g/min
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15. 1. Metabolic
2. Damage to RAS
3. Damage of large portions of cerebral
hemispheres
Small focal lesions of one or both cerebral
hemispheres
Do not cause coma
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16. Suppression of thalamo-cerebral function
Drugs
Toxins
Hypoglycemia
Anoxia
Azotemia
Hepatic failure
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17. What is the date, day, month and year?
Where are you now?
Which is the state capital?
Why are you in the hospital now?
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18. Immediate memory
Repeat 3 to 5 numbers
Show the patient 3 to 5 objects (e.g., pen,
key) to remember
10 minutes later ask him which objects
were shown
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19. Evaluated while the history is being taken
Serial subtraction of 3 from 30 or 7 from 100
Can detect even mild confusional states
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20. Normal light reflex
Normal LP
Normal CT
Bilateral asterixis
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