3. Coal Workers Pneumoconiosis
Coal worker’s pneumoconiosis (CWP) follows prolonged inhalation over 15-20
years of coal dust particles (1-3um in diameter) . Dust-laden alveolar macrophages
aggregate to form macules in or near the centre of the secondary pulmonary
lobule and a fibrotic reaction ensues, resulting in the appearance of scattered
discrete fibrotic lesions.
Classification is based on the size and extent of radiographic nodularity. Simple
coal worker’s pneumoconiosis (SCWP) refers to the appearance of small
radiographic nodules in an otherwise asymptomatic individual.
SCWP does not impair lung function and, once exposure ceases, will seldom
progress.
4. Clinical Features
Asymptomatic, but coexisting chronic bronchitis is common.
Chest X-Ray: many round opacities (1-10mm), especially in upper zone
Management
Avoid exposure to coal dust.
Treat coexisting chronic bronchitis
5. Progressive massive fibrosis (PMF)
Progressive massive fibrosis (PMF) refers to the formation of conglomerate masses
(mainly in the upper lobes), which may cavitate.
Progressive massive fibrosis (PMF) refers to the formation of conglomerate masses
(mainly in the upper lobes), which may cavitate. The development of PMF is
usually associated with cough, sputum that may be black (melanoptysis) and
breathlessness.
The chest X-ray appearances may be confused with lung cancer, TB and
granulomatosis with polyangiitis.
6. Clinical Features
Progressive dyspnea
Fibrosis
Cor pulmonale
Chest X-Ray: Usually bilateral, upper mid zone fibrotic masses, develop from periphery
towards hilum.
Management
Avoid exposure to coal dust.
7. Caplan’s syndrome
PMF may progress, even after coal dust exposure ceases, and in extreme cases
leads to respiratory failure and right ventricular failure
Caplan’s syndrome describes the coexistence of rheumatoid arthritis and rounded
fibrotic nodules 0.5–5 cm in diameter.
They show pathological features similar to a rheumatoid nodule including central
necrosis, palisading histiocytes, and a peripheral rim of lymphocytes and plasma
cells. This syndrome may also occur in other types of pneumoconiosis.