In 2017, the U.S. reported 30,644 cases of primary and secondary syphilis, marking a 10.5% increase from 2016, with higher prevalence in specific racial/ethnic groups and populations like adolescents and MSM. Recommendations for prevention include annual screening for at-risk groups, mobile health units for community-based screening, and increased access to condoms, along with the implementation of expedited partner therapy to treat partners directly. Barriers to these action plans include financial constraints, societal stigma around condom purchase, and legal issues related to partner therapy.