The document discusses the development of an in-house taxonomy database over several decades. It began in 1991 with keywords created by the CEO and has expanded to nearly 1,600 concepts today. The taxonomy is used to organize an internal database and public website on genomic glossaries. Maintaining and updating the taxonomy to integrate new topics and ensure interoperability remains an ongoing challenge. Lessons learned include the importance of modularity, descriptive definitions, and choosing software based on scalability and return on investment.