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The document discusses finding a more environmentally friendly alternative to ibuprofen to address its environmental effects such as waste produced during manufacturing and after consumer use as well as pollution that has led to high amounts of ibuprofen in aquatic ecosystems. It proposes steps to a greener solution such as using efficient production processes, limiting hazardous materials, creating disposal plans for waste, and monitoring laws for chemical pollution from pharmaceutical products in water.
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The document promotes AminoActiv as an alternative to ibuprofen and other non-steroidal anti-inflammatory drugs (NSAIDs) for pain relief. It notes that 33 million people regularly use NSAIDs but spend $8.8 billion on the drugs and $4 billion to treat side effects like gastrointestinal issues, kidney damage, and increased cardiovascular risk. University studies found AminoActiv was as effective as ibuprofen at reducing inflammation without toxic side effects. The all-natural, homeopathic AminoActiv cream and capsules are promoted as a safer option for pain relief from various conditions.
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This document summarizes a graduation thesis on removing ibuprofen from aqueous solutions using adsorption on lentil and rice husk. It discusses the materials and methods used, including the adsorbents (rice husk and lentil husk), adsorbate (ibuprofen), and experimental procedures. The results and discussion section analyzes the effect of pH, adsorbent concentration, and temperature on ibuprofen adsorption. Optimum removal conditions were found to be pH 3, 20g/L rice husk concentration, and room temperature. Adsorption data fitted the Langmuir isotherm model well.
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2012 synthesis and preliminary biological
This document summarizes the synthesis and preliminary biological evaluation of two new ester derivatives of the anti-inflammatory drugs naproxen and ibuprofen linked to cacalol, a natural phenolic compound. Cacalol esters of naproxen (compound 1a) and ibuprofen (compound 1b) were successfully synthesized. Their NMR data and molecular structures were characterized. Preliminary tests showed the compounds had anti-inflammatory and analgesic properties, while blocking the carboxylic acid groups of naproxen and ibuprofen may prevent gastrointestinal irritation.
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The document promotes AminoActiv as an alternative to ibuprofen and other non-steroidal anti-inflammatory drugs (NSAIDs) for pain relief. It notes that 33 million people regularly use NSAIDs but spend $8.8 billion on the drugs and $4 billion to treat side effects like gastrointestinal issues, kidney damage, and increased cardiovascular risk. University studies found AminoActiv was as effective as ibuprofen at reducing inflammation without toxic side effects. The all-natural, homeopathic AminoActiv cream and capsules are promoted as a safer option for pain relief from various conditions.
green chemistry papunaidu nitw
Green chemistry aims to reduce hazardous substances in chemical products and processes. It utilizes 12 principles like prevention of waste, safer solvents and catalysts. The document discusses green synthesis of ibuprofen, adipic acid and maleic anhydride with higher yields, fewer steps and lower energy usage compared to older methods. Recent green reactions highlighted include enantioselective Michael addition in water, oxidation of sulfides with hydrogen peroxide, transformation of alcohols to acids/ketones using t-BuOOH, and borono-Mannich reactions under microwave irradiation without solvents. Green chemistry provides fundamental approaches to pollution prevention.
Ibuprofen
The document demonstrates how to calculate the volume of ibuprofen oral suspension prescribed for a 3 month old infant weighing 6.2 kg at a dose of 5 mg/kg 4 times a day for 6 days. It shows the steps to calculate the amount per dose as 31 mg, the total amount needed as 744 mg, and then the volume of the 100 mg/5 mL suspension required to contain that amount as 37.2 mL.
A1 -ibuprofen_-
The document describes three different synthetic routes for producing the drug ibuprofen and compares their overall yields, time requirements, waste produced, reagent costs and safety, and environmental impact. The original Boots route was the first to synthesize ibuprofen but a greener BHC route was later developed after the patent expired. A new proposed synthesis route is also described and will be compared to the other two methods.
Detoxification of ibuprofen
This document outlines the detoxification of ibuprofen, a common non-steroidal anti-inflammatory drug. It discusses ibuprofen's structure, uses for pain relief and inflammation, mechanism of action by inhibiting cyclooxygenase enzymes, and metabolic detoxification through oxidation and conjugation in the liver. Adverse effects from overuse include gastrointestinal bleeding and renal impairment. The summary concludes that doctors should prescribe appropriate dosages of ibuprofen and patients should seek medical advice before treatment.
Tez
This document summarizes a graduation thesis on removing ibuprofen from aqueous solutions using adsorption on lentil and rice husk. It discusses the materials and methods used, including the adsorbents (rice husk and lentil husk), adsorbate (ibuprofen), and experimental procedures. The results and discussion section analyzes the effect of pH, adsorbent concentration, and temperature on ibuprofen adsorption. Optimum removal conditions were found to be pH 3, 20g/L rice husk concentration, and room temperature. Adsorption data fitted the Langmuir isotherm model well.
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The maximum tolerated daily dose of ibuprofen for a healthy adult is 2400 mg per day. Clinical trials showed ibuprofen doses up to 2400 mg per day for 6 weeks were well tolerated and provided similar efficacy to ibuprofen-phosphatidylcholine. While some sources state the maximum daily dose is 3200 mg, 2400 mg is considered the maximum recommended over-the-counter dose.
Non steroidal anti inflammatory drugs
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WHY SEEK AN ALTERNATIVE TO IBUPROFEN & OTHER NSAIDS?
WHY SEEK AN ALTERNATIVE TO IBUPROFEN & OTHER NSAIDS?
Chem
- 1. A More Green Solution Finding a more environmentally friendly alternative for Ibuprofen
- 2. Ibuprofen’s Environmental Effects Waste •During production •Post-consumer Pollution •High amounts can be found in aquatic ecosystems
- 3. Step by Step
- 5. Steps to a Green Solution Use efficient production processes Limit use of hazardous materials Create a proper disposal plan for waste Create laws for monitoring chemical pollution (from pharmaceutical products) of water
- 6. Steps to a Green Solution Use efficient production processes Limit use of hazardous materials Create a proper disposal plan for waste Create laws for monitoring chemical pollution (from pharmaceutical products) of water