Wellbeing Insights Newsletter August 2015CBIZ, Inc.
This document discusses the importance of immunization awareness and provides recommendations for vaccinations. It recommends that adults speak to their doctors about vaccinations for influenza, tetanus, diphtheria, pertussis, herpes zoster (shingles), pneumococcal disease, measles, mumps, rubella, HPV, varicella, and others depending on risk factors. It also stresses the importance of keeping children's vaccination records up to date.
The October 2015 Edition of Wellbeing Insights is out! This month’s issue talks about everything from breast cancer awareness, since October is Breast Cancer Awareness Month, to flu shot myths and great pumpkin recipes. October’s issue is a must-read!
The latest newsletter of The Advantage talks about how CWA is a continuous effort and spotlights the women that have been leading the charge for the past nine years. With features from Sabrina Rudolph, VP and Controller of Maxwell Technologies, and information of CBIZ women serving as mentors in 16 different cities; this is an issue you just can't miss!
Our June edition of Wellbeing Insights is all about Men's Health. All those tough questions about what screenings to get, to what questions you should be asking your doctor are covered in this jam-packed issue.
CBIZ Wellbeing Insights Newlsetter - November 2014CBIZ, Inc.
This document is a newsletter that provides information on diabetes awareness month and prediabetes. It discusses who is at risk for prediabetes, how it is diagnosed, and lifestyle changes one can make to prevent or delay diabetes if prediabetes is detected. It also profiles actress Halle Berry's experience of being diagnosed with type 1 diabetes at age 22 and how she manages her condition through diet and exercise.
CBIZ Wellbeing Insights Newsletter - March 2015CBIZ, Inc.
We hope you enjoy the March 2015 issue of Wellbeing Insights, our employee wellness newsletter that offers practical tips to inspire readers to make healthy changes in their lives. March is Nutrition Awareness Month.
Wellbeing Insights Newsletter August 2015CBIZ, Inc.
This document discusses the importance of immunization awareness and provides recommendations for vaccinations. It recommends that adults speak to their doctors about vaccinations for influenza, tetanus, diphtheria, pertussis, herpes zoster (shingles), pneumococcal disease, measles, mumps, rubella, HPV, varicella, and others depending on risk factors. It also stresses the importance of keeping children's vaccination records up to date.
The October 2015 Edition of Wellbeing Insights is out! This month’s issue talks about everything from breast cancer awareness, since October is Breast Cancer Awareness Month, to flu shot myths and great pumpkin recipes. October’s issue is a must-read!
The latest newsletter of The Advantage talks about how CWA is a continuous effort and spotlights the women that have been leading the charge for the past nine years. With features from Sabrina Rudolph, VP and Controller of Maxwell Technologies, and information of CBIZ women serving as mentors in 16 different cities; this is an issue you just can't miss!
Our June edition of Wellbeing Insights is all about Men's Health. All those tough questions about what screenings to get, to what questions you should be asking your doctor are covered in this jam-packed issue.
CBIZ Wellbeing Insights Newlsetter - November 2014CBIZ, Inc.
This document is a newsletter that provides information on diabetes awareness month and prediabetes. It discusses who is at risk for prediabetes, how it is diagnosed, and lifestyle changes one can make to prevent or delay diabetes if prediabetes is detected. It also profiles actress Halle Berry's experience of being diagnosed with type 1 diabetes at age 22 and how she manages her condition through diet and exercise.
CBIZ Wellbeing Insights Newsletter - March 2015CBIZ, Inc.
We hope you enjoy the March 2015 issue of Wellbeing Insights, our employee wellness newsletter that offers practical tips to inspire readers to make healthy changes in their lives. March is Nutrition Awareness Month.
CBIZ Wellbeing Insights November 2015 is out! This month's issue puts the spotlight on Type 2 Diabetes. Also included are tips for getting ahead of holiday weight gain and ways to save during the holidays!
The document provides information and tips for sun safety during the month of July which is Sun Care Month. It discusses the dangers of sunburn and unprotected sun exposure, especially for children. It recommends minimizing sun exposure from 10am-4pm, wearing protective clothing and sunscreen with SPF 30 or higher. It also provides information on treating mild and severe sunburns, including first aid steps. The document emphasizes the importance of sun protection to prevent skin cancer.
In this issue of Wellbeing Insights, we'll discuss important tips and information about Heart Health, including corornary disease, exercise tips and more!
Does an apple a day really keep the doctor away?
Is 100 an obtainable number for us living in the 21st century?
Find out all that and more in this month's issue of Wellbeing Insights. Also, September is National Suicide Prevention Month. Learn some fast facts and preventive measures about the 10th leading cause of death of Americans.
In this issue of Wellbeing Insights, we feature articles about Breast Cancer Awareness, health eating, exercise tips and more! Learn more about CBIZ Wellness Solutions at www.cbiz.com
The latest issue of CBIZ Wellbeing Insights is here! The February issues features an in-depth look at heart disease and why it's the #1 cause of deaths worldwide. Also included is a nice financial focus on tackling tax season and the hidden health risks of artificial sweeteners. Check the presentation for all that and much more!
The CBIZ Wellbeing Insights for December 2016 has been released. The latest publication places an emphasis on beating those winter blues, goal-setting for the new year, year-end tax reductions tips and much more.
The latest issue of CBIZ Wellbeing Insights has been released. The March issue features a lenghty discussion on the importance of sleep and tips on how to get more of it. Also included is a nice section on becoming flexibly fit. Rounding out the publication is a slew of information on the financial benefits of a healthy lifestyle.
The latest Retirement Plan News contains articles on the following: 1) Make Benchmarking Your Plan An Annual Exercise 2) Employer Contribution Trends 3) QDIAS Ten years On
This document provides 10 guidelines for having a happy holiday season while managing increased stressors like travel, shopping, work deadlines, finances and unrealistic expectations. It suggests managing expectations by letting go of pressure for perfection, learning to say no to overcommitting, slowing down to enjoy moments, making time for yourself, giving back through acts of service, being grateful, embracing nostalgia, staying active, acknowledging all feelings, and letting go of what doesn't go as planned by focusing on relationships over expectations. The overall message is to find balance and meaning amid the hustle of the holidays.
October is Breast Cancer Awareness Month! In this issue, we go over the importance of mammograms, delve into ways to stay healthy during the fall months and much more!
The latest CBIZ Wellbeing Insights has been released! Get information on the following topics in the August publication: 10 keys to a happier lifestyle, back to school tips for parents, how to buy happiness and much more!
This document discusses several topics related to health and wellness. It begins by promoting National Blood Donor Month in January and encourages readers to donate blood which is in short supply during the winter months. It then discusses Cervical Health Awareness Month and provides information about cervical cancer prevention through regular Pap tests and HPV vaccination. The document offers tips for boosting immunity and preventing sickness. It highlights the health benefits of turmeric and provides a recipe for turmeric tea. A section on mindful living encourages readers to start each day with intention. Home remedies for congestion include DIY shower disks. The document aims to clarify common misconceptions about carbohydrates and recommends which carbs are best and worst for health. It
BIZGrowth Strategies — Cybersecurity Special Edition 2023CBIZ, Inc.
As cybercriminals continue to advance and evolve, a stagnant cyber risk management approach is simply not an option. Further, the prevalence of cyber breaches means cybersecurity is not solely an IT concern. It takes a robust set of processes and people from across your organization, working together toward a common goal. We offer fresh insights to help protect your organization from cyberthreats in multiple operational areas. Articles include:
- How Cybercriminals Are Weaponizing Artificial Intelligence
- Employee Benefits Cyber Risk Exposure Scorecard
- Closing the Security Gap: Managing Vendor Cyber Risk
- Retirement Plan Sponsor Cybersecurity Checklist
- Protect Your Digital Frontline With Employee Training
BIZGrowth Strategies - Back to Basics Special EditionCBIZ, Inc.
Amid the increasing complexity of today’s business landscape, it can be of great benefit to shut out the noise and simply get back to the basics. Summer offers the rare opportunity for organizations to slow down and sweat the small stuff.
In this issue, our experts address seven key topics intended to help leaders guide their teams to stability and refocus on the foundational elements of success, including:
- Talent Management 101: How to Attract & Retain Great Employees
- Exploring the What, Why & How Behind the Employee Experience
- The Shifting Normal: 3 Ways Leaders Can Embrace Change & Conquer Challenge
- What is Financial Wellbeing & Why Should Employers Care?
- D&O Insurance Application Basics to Protect Your Leaders
- Your Life Insurance Policy May Be One of Your Biggest Assets
- Understanding Labor Law Poster Compliance
Welcome to our newly branded newsletter, "The Advantage." The articles in this issue provide insights to help you:
■ Have conversations around tough decisions during periods of economic uncertainty
■ Evaluate fast-growing artificial intelligence tools like ChatGPT
■ Recognize colleagues who are key allies in supporting women in the workplace
■ Navigate career shifts along the path to successful leadership
■ Manage workplace culture in a hybrid model
■ Garner inspiration from the 2023 Women Transforming Business finalists and winners
BIZGrowth Strategies - Workforce & Talent Optimization Special EditionCBIZ, Inc.
Amid today’s economic uncertainty, we know you need strategies and solutions that will help your business thrive. With workforce and talent concerns running high for employers across the nation, our experts developed these articles with those critical issues top of mind. We offer fresh insights designed to attract, retain, engage and motivate your employees — all while protecting your bottom line and managing emerging risks. Articles include:
- Unlock Success with Effective Performance Management
- How Employers Can Benefit from Financial Wellbeing Programs
- How to Talk About Hard Decisions During a Recession
- Cost-Effective Health Plan Perks to Consider in 2023
- 3 HR Strategies to Recession-Proof Your Organization
- Responding to Employment Practices Liability (EPL) Claims
- Versatility — Important in Life & Life Insurance
BIZGrowth Newsletter - Economic Slowdown Solutions Special EditionCBIZ, Inc.
The "Economic Slowdown Solutions Special Edition" newsletter includes articles that present tips, strategies and ideas to help your organization master economic uncertainty and recessionary concerns. Topics include:
- Considerations for a Reduction in Force
- Tips to Prepare for Risk Management Challenges
- Tactics to Recession-Proof Your Benefits Strategy
- HR Best Practices
- Recruitment Strategies to Keep You Competitive
- 3 Innovations to Stay Nimble
- Disability Insurance for Business Owners
BIZGrowth Strategies - Cybersecurity Special EditionCBIZ, Inc.
Cyberattacks are becoming more frequent and sophisticated, making a recovery from them increasingly difficult. Without preparation, a cyberattack can be devastating to your business, having severe operational, financial, legal and reputational implications.
The prevalence of cyber breaches also means cybersecurity is no longer solely an IT concern. Elevating your information security from functional to effective takes a robust set of elements, processes and people working together toward a common goal.
Our professionals have developed these articles and resources to help you protect your organization from these attacks.
Connections Help Law Practice Efficiently Obtain $5 Million Line of CreditCBIZ, Inc.
A 15-attorney law firm operated on a contingency and hourly fee basis. While it had a strong outlook for contingency cases, the costs incurred to work...
Custom Communication Plan & Active Enrollment Result in Increased ConsumerismCBIZ, Inc.
The firm embarked on a multi-year strategic plan to build a culture of wellbeing and engagement. They wanted
to educate employees to become more engaged and wise health care consumers...
Experienced Consulting Approach Leads Engineering Firm to the Right CFOCBIZ, Inc.
The Chief Financial Officer of a leading multi-disciplined engineering and consulting
firm indicated he was considering retiring. After initially considering a search process as an in-house project, the company’s leadership agreed...
CBIZ Wellbeing Insights November 2015 is out! This month's issue puts the spotlight on Type 2 Diabetes. Also included are tips for getting ahead of holiday weight gain and ways to save during the holidays!
The document provides information and tips for sun safety during the month of July which is Sun Care Month. It discusses the dangers of sunburn and unprotected sun exposure, especially for children. It recommends minimizing sun exposure from 10am-4pm, wearing protective clothing and sunscreen with SPF 30 or higher. It also provides information on treating mild and severe sunburns, including first aid steps. The document emphasizes the importance of sun protection to prevent skin cancer.
In this issue of Wellbeing Insights, we'll discuss important tips and information about Heart Health, including corornary disease, exercise tips and more!
Does an apple a day really keep the doctor away?
Is 100 an obtainable number for us living in the 21st century?
Find out all that and more in this month's issue of Wellbeing Insights. Also, September is National Suicide Prevention Month. Learn some fast facts and preventive measures about the 10th leading cause of death of Americans.
In this issue of Wellbeing Insights, we feature articles about Breast Cancer Awareness, health eating, exercise tips and more! Learn more about CBIZ Wellness Solutions at www.cbiz.com
The latest issue of CBIZ Wellbeing Insights is here! The February issues features an in-depth look at heart disease and why it's the #1 cause of deaths worldwide. Also included is a nice financial focus on tackling tax season and the hidden health risks of artificial sweeteners. Check the presentation for all that and much more!
The CBIZ Wellbeing Insights for December 2016 has been released. The latest publication places an emphasis on beating those winter blues, goal-setting for the new year, year-end tax reductions tips and much more.
The latest issue of CBIZ Wellbeing Insights has been released. The March issue features a lenghty discussion on the importance of sleep and tips on how to get more of it. Also included is a nice section on becoming flexibly fit. Rounding out the publication is a slew of information on the financial benefits of a healthy lifestyle.
The latest Retirement Plan News contains articles on the following: 1) Make Benchmarking Your Plan An Annual Exercise 2) Employer Contribution Trends 3) QDIAS Ten years On
This document provides 10 guidelines for having a happy holiday season while managing increased stressors like travel, shopping, work deadlines, finances and unrealistic expectations. It suggests managing expectations by letting go of pressure for perfection, learning to say no to overcommitting, slowing down to enjoy moments, making time for yourself, giving back through acts of service, being grateful, embracing nostalgia, staying active, acknowledging all feelings, and letting go of what doesn't go as planned by focusing on relationships over expectations. The overall message is to find balance and meaning amid the hustle of the holidays.
October is Breast Cancer Awareness Month! In this issue, we go over the importance of mammograms, delve into ways to stay healthy during the fall months and much more!
The latest CBIZ Wellbeing Insights has been released! Get information on the following topics in the August publication: 10 keys to a happier lifestyle, back to school tips for parents, how to buy happiness and much more!
This document discusses several topics related to health and wellness. It begins by promoting National Blood Donor Month in January and encourages readers to donate blood which is in short supply during the winter months. It then discusses Cervical Health Awareness Month and provides information about cervical cancer prevention through regular Pap tests and HPV vaccination. The document offers tips for boosting immunity and preventing sickness. It highlights the health benefits of turmeric and provides a recipe for turmeric tea. A section on mindful living encourages readers to start each day with intention. Home remedies for congestion include DIY shower disks. The document aims to clarify common misconceptions about carbohydrates and recommends which carbs are best and worst for health. It
BIZGrowth Strategies — Cybersecurity Special Edition 2023CBIZ, Inc.
As cybercriminals continue to advance and evolve, a stagnant cyber risk management approach is simply not an option. Further, the prevalence of cyber breaches means cybersecurity is not solely an IT concern. It takes a robust set of processes and people from across your organization, working together toward a common goal. We offer fresh insights to help protect your organization from cyberthreats in multiple operational areas. Articles include:
- How Cybercriminals Are Weaponizing Artificial Intelligence
- Employee Benefits Cyber Risk Exposure Scorecard
- Closing the Security Gap: Managing Vendor Cyber Risk
- Retirement Plan Sponsor Cybersecurity Checklist
- Protect Your Digital Frontline With Employee Training
BIZGrowth Strategies - Back to Basics Special EditionCBIZ, Inc.
Amid the increasing complexity of today’s business landscape, it can be of great benefit to shut out the noise and simply get back to the basics. Summer offers the rare opportunity for organizations to slow down and sweat the small stuff.
In this issue, our experts address seven key topics intended to help leaders guide their teams to stability and refocus on the foundational elements of success, including:
- Talent Management 101: How to Attract & Retain Great Employees
- Exploring the What, Why & How Behind the Employee Experience
- The Shifting Normal: 3 Ways Leaders Can Embrace Change & Conquer Challenge
- What is Financial Wellbeing & Why Should Employers Care?
- D&O Insurance Application Basics to Protect Your Leaders
- Your Life Insurance Policy May Be One of Your Biggest Assets
- Understanding Labor Law Poster Compliance
Welcome to our newly branded newsletter, "The Advantage." The articles in this issue provide insights to help you:
■ Have conversations around tough decisions during periods of economic uncertainty
■ Evaluate fast-growing artificial intelligence tools like ChatGPT
■ Recognize colleagues who are key allies in supporting women in the workplace
■ Navigate career shifts along the path to successful leadership
■ Manage workplace culture in a hybrid model
■ Garner inspiration from the 2023 Women Transforming Business finalists and winners
BIZGrowth Strategies - Workforce & Talent Optimization Special EditionCBIZ, Inc.
Amid today’s economic uncertainty, we know you need strategies and solutions that will help your business thrive. With workforce and talent concerns running high for employers across the nation, our experts developed these articles with those critical issues top of mind. We offer fresh insights designed to attract, retain, engage and motivate your employees — all while protecting your bottom line and managing emerging risks. Articles include:
- Unlock Success with Effective Performance Management
- How Employers Can Benefit from Financial Wellbeing Programs
- How to Talk About Hard Decisions During a Recession
- Cost-Effective Health Plan Perks to Consider in 2023
- 3 HR Strategies to Recession-Proof Your Organization
- Responding to Employment Practices Liability (EPL) Claims
- Versatility — Important in Life & Life Insurance
BIZGrowth Newsletter - Economic Slowdown Solutions Special EditionCBIZ, Inc.
The "Economic Slowdown Solutions Special Edition" newsletter includes articles that present tips, strategies and ideas to help your organization master economic uncertainty and recessionary concerns. Topics include:
- Considerations for a Reduction in Force
- Tips to Prepare for Risk Management Challenges
- Tactics to Recession-Proof Your Benefits Strategy
- HR Best Practices
- Recruitment Strategies to Keep You Competitive
- 3 Innovations to Stay Nimble
- Disability Insurance for Business Owners
BIZGrowth Strategies - Cybersecurity Special EditionCBIZ, Inc.
Cyberattacks are becoming more frequent and sophisticated, making a recovery from them increasingly difficult. Without preparation, a cyberattack can be devastating to your business, having severe operational, financial, legal and reputational implications.
The prevalence of cyber breaches also means cybersecurity is no longer solely an IT concern. Elevating your information security from functional to effective takes a robust set of elements, processes and people working together toward a common goal.
Our professionals have developed these articles and resources to help you protect your organization from these attacks.
Connections Help Law Practice Efficiently Obtain $5 Million Line of CreditCBIZ, Inc.
A 15-attorney law firm operated on a contingency and hourly fee basis. While it had a strong outlook for contingency cases, the costs incurred to work...
Custom Communication Plan & Active Enrollment Result in Increased ConsumerismCBIZ, Inc.
The firm embarked on a multi-year strategic plan to build a culture of wellbeing and engagement. They wanted
to educate employees to become more engaged and wise health care consumers...
Experienced Consulting Approach Leads Engineering Firm to the Right CFOCBIZ, Inc.
The Chief Financial Officer of a leading multi-disciplined engineering and consulting
firm indicated he was considering retiring. After initially considering a search process as an in-house project, the company’s leadership agreed...
Check out the latest edition for articles on Preventing Social Engineering Attacks, Triumphing in the Talent War, 3 Signs It’s Time for a Compensation Study, Strategies to Protect Your Retirement & Tips for a Successful OSHA Inspection.
Inflation, Interest Rates & the Disruption to CRECBIZ, Inc.
From assessing the various sectors to analyzing the future of your investments, learn more from our experienced team leaders on the wide-spread trends of commercial real estate property and sales.
CBIZ Quarterly Manufacturing and Distribution "Hot Topics" Newsletter (May-Ju...CBIZ, Inc.
CBIZ Quarterly Manufacturing and Distribution "Hot Topics" Newsletter (May-Jun 2022) provides you with news and guidance on the labor crisis, how to retain top talent during the Great Resignation, the business impacts of the Russia-Ukraine War, and the benefit of long-term bonus plans.
Rethinking Total Compensation to Retain Top TalentCBIZ, Inc.
Even with a developed recruiting program, strong company culture and great work-life balance, it’s difficult for companies to attract and retain the best employees without an all-inclusive compensation strategy. Add in the combination of high inflation, talent shortages and the Great Resignation, and we’re left with a hyper-competitive labor market. As a result, employers must think outside of the box to retain top performers and explore new ways to increase the value of total compensation offered. Learn how in this article.
Common Labor Shortage Risks & Tips to Mitigate Your ExposuresCBIZ, Inc.
No industry is safe from the risks of the current labor market. Employee shortages can influence multiple liabilities, but a proactive strategy can help protect your organization. In this article, learn measures to minimize labor shortage liability risks across all industries, as well as influential industry risks for construction, manufacturing and trucking.
How the Great Resignation Affects the Tax FunctionCBIZ, Inc.
Talent shortages remain a challenge universally, but it may be hitting financial roles within businesses particularly hard. The
pressures to meet tax reform obligations coupled with the
job changeover opportunities that emerged during the Great Resignation have left many tax departments feeling under-resourced. If your company is experiencing a similar situation, here are steps you can take to support your tax function.
While employee turnover is inevitable, there are several strategies companies can implement to help combat the Great Resignation, and at the center of all these strategies is technology that can benefit employers and their staff. In this article, learn how your organization can use technology to enhance the recruiting and onboarding processes, which will help attract top talent, while setting new hires up for success.
Experienced Consulting Approach Leads Engineering Firm to the Right CFOCBIZ, Inc.
The Chief Financial Officer of a leading multi-disciplined engineering and consulting firm indicated he was considering retiring. After initially considering a search process as an in-house project, the company’s leadership agreed to secure the assistance of an executive search professional.
BIZGrowth Strategies - The Great Resignation Special EditionCBIZ, Inc.
The Great Resignation continues to plague organizations across the country. It has exacerbated a host of employer challenges, including attraction, retention and engagement of top talent, as well as mitigating new risks. Our experts have developed these articles and linked resources to help your organization combat the mass employee exodus.
Kansas businesses have an opportunity for state tax incentives of which you may want to be aware.
Recent changes to the Kansas High Performance Incentive Program (HPIP) make it more broadly available
than it was in the past.
CBIZ Quarterly Commercial Real Estate "Hot Topics" Newsletter (Jan-Feb 2022)CBIZ, Inc.
The January 2022 issue of CBIZ’s Commercial Real Estate Quarterly Hot Topics Newsletter is now available! Learn about the impact of changes lease accounting, post-pandemic calculation companies are using to reassess office space needs, tax planning knowns and unknowns and the impact of rising construction costs on insurance costs. Plus – access strategies to combat the great resignation and safeguard against the unexpected.
Travel vaccination in Manchester offers comprehensive immunization services for individuals planning international trips. Expert healthcare providers administer vaccines tailored to your destination, ensuring you stay protected against various diseases. Conveniently located clinics and flexible appointment options make it easy to get the necessary shots before your journey. Stay healthy and travel with confidence by getting vaccinated in Manchester. Visit us: www.nxhealthcare.co.uk
The skin is the largest organ and its health plays a vital role among the other sense organs. The skin concerns like acne breakout, psoriasis, or anything similar along the lines, finding a qualified and experienced dermatologist becomes paramount.
These lecture slides, by Dr Sidra Arshad, offer a simplified look into the mechanisms involved in the regulation of respiration:
Learning objectives:
1. Describe the organisation of respiratory center
2. Describe the nervous control of inspiration and respiratory rhythm
3. Describe the functions of the dorsal and respiratory groups of neurons
4. Describe the influences of the Pneumotaxic and Apneustic centers
5. Explain the role of Hering-Breur inflation reflex in regulation of inspiration
6. Explain the role of central chemoreceptors in regulation of respiration
7. Explain the role of peripheral chemoreceptors in regulation of respiration
8. Explain the regulation of respiration during exercise
9. Integrate the respiratory regulatory mechanisms
10. Describe the Cheyne-Stokes breathing
Study Resources:
1. Chapter 42, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 36, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 13, Human Physiology by Lauralee Sherwood, 9th edition
Travel Clinic Cardiff: Health Advice for International TravelersNX Healthcare
Travel Clinic Cardiff offers comprehensive travel health services, including vaccinations, travel advice, and preventive care for international travelers. Our expert team ensures you are well-prepared and protected for your journey, providing personalized consultations tailored to your destination. Conveniently located in Cardiff, we help you travel with confidence and peace of mind. Visit us: www.nxhealthcare.co.uk
PGx Analysis in VarSeq: A User’s PerspectiveGolden Helix
Since our release of the PGx capabilities in VarSeq, we’ve had a few months to gather some insights from various use cases. Some users approach PGx workflows by means of array genotyping or what seems to be a growing trend of adding the star allele calling to the existing NGS pipeline for whole genome data. Luckily, both approaches are supported with the VarSeq software platform. The genotyping method being used will also dictate what the scope of the tertiary analysis will be. For example, are your PGx reports a standalone pipeline or would your lab’s goal be to handle a dual-purpose workflow and report on PGx + Diagnostic findings.
The purpose of this webcast is to:
Discuss and demonstrate the approaches with array and NGS genotyping methods for star allele calling to prep for downstream analysis.
Following genotyping, explore alternative tertiary workflow concepts in VarSeq to handle PGx reporting.
Moreover, we will include insights users will need to consider when validating their PGx workflow for all possible star alleles and options you have for automating your PGx analysis for large number of samples. Please join us for a session dedicated to the application of star allele genotyping and subsequent PGx workflows in our VarSeq software.
Breast cancer: Post menopausal endocrine therapyDr. Sumit KUMAR
Breast cancer in postmenopausal women with hormone receptor-positive (HR+) status is a common and complex condition that necessitates a multifaceted approach to management. HR+ breast cancer means that the cancer cells grow in response to hormones such as estrogen and progesterone. This subtype is prevalent among postmenopausal women and typically exhibits a more indolent course compared to other forms of breast cancer, which allows for a variety of treatment options.
Diagnosis and Staging
The diagnosis of HR+ breast cancer begins with clinical evaluation, imaging, and biopsy. Imaging modalities such as mammography, ultrasound, and MRI help in assessing the extent of the disease. Histopathological examination and immunohistochemical staining of the biopsy sample confirm the diagnosis and hormone receptor status by identifying the presence of estrogen receptors (ER) and progesterone receptors (PR) on the tumor cells.
Staging involves determining the size of the tumor (T), the involvement of regional lymph nodes (N), and the presence of distant metastasis (M). The American Joint Committee on Cancer (AJCC) staging system is commonly used. Accurate staging is critical as it guides treatment decisions.
Treatment Options
Endocrine Therapy
Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include:
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
Chemotherapy
Chemotherapy is generally reserved for patients with high-risk features, such as large tumor size, high-grade histology, or extensive lymph node involvement. Regimens often include anthracyclines and taxanes.
Know the difference between Endodontics and Orthodontics.Gokuldas Hospital
Your smile is beautiful.
Let’s be honest. Maintaining that beautiful smile is not an easy task. It is more than brushing and flossing. Sometimes, you might encounter dental issues that need special dental care. These issues can range anywhere from misalignment of the jaw to pain in the root of teeth.
“Psychiatry and the Humanities”: An Innovative Course at the University of Mo...Université de Montréal
“Psychiatry and the Humanities”: An Innovative Course at the University of Montreal Expanding the medical model to embrace the humanities. Link: https://www.psychiatrictimes.com/view/-psychiatry-and-the-humanities-an-innovative-course-at-the-university-of-montreal
1. January 2015
January is Stress Management Month
Superfood
of the Month
Exercise of
the Month
WELLBEING
Insights
R
Living a Better, More Vibrant Life
2. According to a large study, workers who chew gum
report less stress than their gum-free colleagues.
This is because chomping on a stick of gum
stimulates the vagus nerve, which helps induce
relaxation. Just make sure your gum is sugar-free.
Tea for Stress
The British have the right idea when they brew a pot
of tea during stressful times. It turns out that black
tea is rich in stress-busting antioxidants, including
polyphenols, flavonoids and amino acids. There is
also some evidence that green tea can help lower
harmful LDL cholesterol. Have a cup!
Laugh Away Stress
When it comes to stress, laughter really is a good
medicine. A good belly laugh triggers production of
endorphins, the brain's feel-good neurotransmitters. It
also relaxes your blood vessels and increases blood
flow — the ideal antidote to tension.
Take a Walk
If stress is a constant companion, add a 20 to
30-minute walk to your daily routine. Walking and
other forms of exercise help reduce anxiety. Even
better, take your stroll in a neighborhood park.
January is Stress Management Month. The holidays
are over and everyone has to get back to work.
There is no surprise that the New Year leads to a
variety of different stress levels.
Stress is bad for your overall well-being, including
your cholesterol, but small changes to your everyday
routine can help reduce stress. From aromatherapy
to chewing gum, to walking, here are several speedy
tension-relievers.
How About Aromatherapy?
Is stress getting to you? If yes, it is time to stop and
smell the roses. They contain linalool, a chemical
that helps reduce stress. So do herbs, such as
lavender and basil, and fruit, such as oranges,
grapes and mangoes. That is another good excuse
to keep a bouquet of flowers, dried lavender or a
bowl of fruit nearby. They smell lovely and can
benefit your cholesterol.
Chew Gum, Fight Stress
Chewing gum is a great stress-buster and a little
treat that will not hurt your cholesterol.
January is Stress
Management Month
3. A recent Japanese study revealed that walking outside, especially in a forest setting, is
an effective way to combat chronic stress.
Spend Time With Your Pets
Whether you live with a dog, a cat or even a bird, stress reduction is one of the great
benefits of an animal companion. In one study, just watching 10 minutes of cute
animal film was enough to lower volunteers' heart rates and blood pressure when
they were stressed. Other research has linked pet ownership with significantly
lower triglyceride and cholesterol levels.
Find a Room With a View
Next time you are overwhelmed, turn off the computer screen and look out of the window
instead. One study revealed that students sitting at window seats recovered faster from performing a series of
stressful tasks than classmates who faced a blank wall or even a high-definition plasma screen displaying a
nature scene. The more time they spent gazing at the view, the faster their heart rates dropped back to
normal. Hmmm . . . that is a good excuse to ask your boss for an office with a window.
Listen to Music
As you load your personal soundtrack onto your iPod, include a medley of relaxing music to take the edge off
stress. Listening to mellow tunes with a slow, steady rhythm helps to slow down your breathing and heart rate
so you feel calmer. Whether you are a fan of Enya or Gregorian chants, you can find something that suits your
style.
Whatever you decide to do to relieve stress, make sure it is
enjoyable. If you are unable to contain your stress, consult your
doctor immediately.
How she deals with stress…
Being a worldwide celebrity, philanthropist and movie star can be
extremely stressful. For celebrity Angelina Jolie, balancing life and
managing her stress includes the simple things in life. Jolie told
Stylist Magazine that she has a hard time calming down with all the
chaos in her home, so she tries to find peace in the little things that
bring her joy.
Jolie says, "I find meditation in sitting on the floor with the kids
coloring for an hour or going on the trampoline. You do something
you love, that makes you happy, and that gives you your meditation.
But I think it's good I'm not somebody who needs quiet moments
because I never get them. They're very rare."
Worldwide superstar Jolie balances her
stressful life by meditating and spending
time with her children.
Contributed by:
4. Nutrition Facts
Serving Size: about 8 to 10 fries
Calories 115
Fat 8.8 g
Total Carbs 6.6 g
Protein 3.75 g
Do you ever wonder what you can do to help with
your french fry addiction? This healthy eggplant
recipe will please you and the entire family.
Ingredients
1 medium eggplant, cut into 1/4” fries
1 cup of almond flour/meal + 2 Tbsp.
arrowroot powder OR 1-1/2 cups of cornmeal
2 eggs, lightly beaten
1-1/2 teaspoon fine grain sea salt, divided
1/2 teaspoon dried oregano
1/2 teaspoon garlic powder
1/2 teaspoon paprika
1 Tbsp. olive oil
Preparation
Lay eggplant matchsticks in a single layer on
a baking sheet lined with paper towels.
Sprinkle with 1 teaspoon of salt and let stand
for 25 minutes.
At the 25-minute mark, pat dry the eggplant
matchsticks with paper towels.
Preheat oven to 400°F (200°C) and place a
rack in the middle of the oven. Lightly grease
a baking sheet with olive oil.
In a medium bowl, combine remaining
½ teaspoon of salt, almond meal plus
arrowroot powder (or cornmeal), garlic
powder, paprika and oregano.
Crack two eggs in a small bowl and lightly
beat.
One by one, dip the eggplant fries in the
beaten eggs and transfer to the almond meal
mixture (or cornmeal), being sure to coat
them thoroughly.
Place eggplant fries on a baking sheet and
bake for 20-25 minutes, flipping them at the
12 minute mark.
Crispy Baked
Eggplant Fries
5. This winter fruit is a healthy way to satisfy
your sweet tooth. A clementine is a hybrid
between a mandarin and a sweet orange. The
exterior is a deep orange color with a smooth,
glossy appearance. Clementines can be
separated into 7 to 14 segments.
Superfood of the Month
Clementines
Clementines pack a punch when it
comes to vitamin C. Just one
clementine contains 36 milligrams,
which is 60 percent of your daily value
of vitamin C. Whether working as an
antioxidant or synthesizing essential
substances, such as collagen and
neurotransmitters, vitamin C has quite
an impact on your health. As an
antioxidant, it protects cells, proteins,
fats, carbohydrates and DNA from
damage caused by free radicals. Your
skin depends on vitamin C to protect its
cells from free radicals formed in
response to sunlight. It is essential for
the synthesis of the connective tissue,
collagen, which supports tendons, your
skin, blood vessels, bones and tissues
throughout the body.
Health Benefits of Eating Clementines
Nutrition Facts
Serving Size: 1
Calories 35
Total Fat 0 g
Sodium 1 mg
Fiber 1 g
Total Carbs 9 g
Protein 1 g
Sugars 7 g
6. Starting Your
2015 New
Year Fitness
Plan
Starting a fitness program may be one of the best things that you can do for your health
and well-being. Physical activity can reduce your risk of chronic disease, improve balance
and coordination and even help you loose weight and improve your self-esteem. Here are
several simple steps that you can take to start your program:
1) Consult your physician to make sure that you are physically able to start a workout
program.
2) Assess your fitness level by recording a baseline and benchmark your progress. You
should consider recording:
Your pulse rate before and after you walk 1 mile
How long it takes you to walk 1 mile
How many pushups you can do at one time
How far you can reach in front of you, seated on the floor with your legs in front of
you
Your waist circumference
Your body mass index
3) Design your fitness program.
Create fitness goals (lose weight or preparing for a marathon)
Create a balanced routine by aiming for at least 150 minutes of
moderate-intensity aerobic activity a week
Build activity into your daily routine by finding time to exercise
Plan variety in your exercise program to keep it interesting
Allow for recovery time, including sleep and rest
Document your activity and progress in a journal or personal fitness device
4) Assemble the equipment needed to start your activities, such as correctly fitting athletic
shoes and socks, personal fitness devices and activity logs.
5) Get started slowly and plan for building up gradually.
6) Monitor your progress so that you can see your improvements which will be motivating
and inspiring.
7) Share your achievements with others including your physician.
During the year, we will be featuring basic exercises each month that can help you shape
up and get fit. Be on the lookout each issue for the Exercise of the Month column for more
information.
So, you are going to
start a personal
Fitness Plan in 2015?
Good for You…
Get Fit and Become a
HealthierU this New
Year!
7. Coconut Milk or Whipping Cream
Coconut milk is much lower in calories and can give the same creamy consistency in your soups and stews.
Try this substitution today to lower your calorie intake.
Not That...Eat This...
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please feel free to send a brief letter and
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Thank you for reading and contributing. We
sincerely hope that we can become a
healthier part of becoming a healthier you.