The document discusses the causes of mesothelioma. Asbestos exposure is the primary cause, with 11 million people exposed between 1940-1983 in the US. This led to a sharp rise in mesothelioma cases from the 1970s-1990s. Asbestos regulations in the 1980s helped reduce exposure. Other potential causes discussed include radiation therapy, SV40 virus, genetic factors, and erionite exposure. While asbestos usage is now regulated in many countries, some developing nations still use it. This history of asbestos exposure means mesothelioma cases will continue for years.

1. auses
of
mesothelioma

2. Asbestos

3. Asbestos is the commercial name for a group of
hydrated silicate fibrous materials.
1

4. Chrysotile Amosite
Crocidolite
Tremolite
Serpentine Amphibole
Anthophyllite
Actinolite
Asbestos is the commercial name for a group of
hydrated silicate fibrous materials.
1
there are
two types
of asbestos
2

5. 11 million
exposed people between 1940-783

6. 11 million
exposed people between 1940-783
expected latency period after exposure
25-50 years

7. 11 million
exposed people between 1940-783
expected latency period after exposure
25-50 years
sharp increase in mesothelioma cases in the US
1970s – 1990s
leveled
off in
1992

8. 11 million
exposed people between 1940-783
expected latency period after exposure
25-50 years
sharp increase in mesothelioma cases in the US
1970s – 1990s
asbestos regulations were passed1980s

9. 11 million
exposed people between 1940-783
expected latency period after exposure
25-50 years
sharp increase in mesothelioma cases in the US
1970s – 1990s
asbestos regulations were passed1980s
trace amounts of asbestos may still be allowed legally

10. 11 million
exposed people between 1940-783
expected latency period after exposure
25-50 years
sharp increase in mesothelioma cases in the US
1970s – 1990s
asbestos regulations were passed1980s
trace amounts of asbestos may still be allowed legally
some developing countries still continue to use asbestos

11. 11 million
exposed people between 1940-783
expected latency period after exposure
25-50 years
sharp increase in mesothelioma cases in the US
1970s – 1990s
asbestos regulations were passed1980s
trace amounts of asbestos may still be allowed legally
some developing countries still continue to use asbestos
All of this add up to the persistence of
mesothelioma in the coming years

12. Country Production (metric tons)
Russia 1,000,000
China 400,000
Brazil 270,000
Kazakhstan 214,000
Canada 100,000
Major Producers of Asbestos 5

13. Asbestos cement sheets
Fire rated doors
Asbestos cement pipes
Low density insulating boards
Brake pads
replaced
since
1995
Vinyl floor tiles
Fireproofing
Acoustic ceilings
Gaskets
Drilling fluid additives
also in:
 Mining
 Ship building
 Paper milling
 Railroad repair
 Ceramics
Sources
of
Asbestos
Sources
of
Asbestos

14. Carbon Nanotubes

15. Carbon nanotubes are allotropes of carbon with a
wide array of applications in electronics, optics
4
Animal
Models
only
similar dimensions and chemical property as asbestos

16. Carbon nanotubes are allotropes of carbon with a
wide array of applications in electronics, optics
4
Animal
Models
only
Single-walled
Multi-walled
Nanotorus
Nanobud
Grafinated
Nitrogen doped
Peapod
Extreme
Cup-stacked
There are
different
types

17. What are the current applications of carbon nanotubes?
Wind turbines
Marine paints
Ice hockey sticks
Surf boards
Baseball bats
Maritime vessels
Handlebars
Seat posts
Scaffolding for bone growth
Golf clubs

18. Simian Virus 40

19. SV-40 is the 50s & 60s polio vaccine contaminant
Mixed
Reviews

20. SV-40 is the 50s & 60s polio vaccine contaminant
Mixed
Reviews
10-30 million people exposed to SV-40
contaminated polio vaccines
1955-63

21. BAP1 gene defects

22. Official Name: BRCA1 Associated Protein-1
Regulate key histones and transcription factors
related to tumor development
BAP1 gene is located on chromosome 3

23. Other
Potential
Causes

24. Radiation therapy
Radiation to supradiaphragmatic fields
Other
Potential
Causes

25. Radiation therapy
Radiation to supradiaphragmatic fields
Intrapleural thorium dioxide
Other
Potential
Causes

26. Radiation therapy
Radiation to supradiaphragmatic fields
Intrapleural thorium dioxide
Zeolites
Other
Potential
Causes
An example is erionite which is common in Turkey

27. References
1. Daniel H Sterman, MD, et al. Epidemiology of malignant
mesothelioma. UpToDate version 19.3
2. Wikipedia, the free encyclopedia. Mesothelioma
3. National Institute of Health
4. Wikipedia, the free encyclopedia. Carbon nanotubes
5. U.S. Geological Survey, Mineral Commodity Summaries
updated March, 2013

28. What Next?
What are the symptoms of mesothelioma?
How is mesothelioma diagnosed?
What is the survival rate of mesothelioma?
How is mesothelioma treated?
Checkout mesosupport.blogspot.com to learn more. We will
guide you through everything related to mesothelioma –
from what’s to what of’s to laws to treatments