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Passive Leg Raise
                   to test for fluid response




www.uscom.com.au                    The Measure of Life
Post Passive Leg Raise




                                  19% increase


www.uscom.com.au                  The Measure of Life
Possible passive leg raising
                   false negative tests
           Conditions of high intra-abdominal pressure
             …should be noted that intra-abdominal hypertension (intra-abdominal pressure > 16
           mm Hg) impairs venous return and reduces the ability of PLR to detect fluid
           responsiveness [54]...
           Marik et al. Annals of Intensive Care 2011, 1:1

           States of severe dehydration
           …the blood volume mobilized by leg raising is dependent on total blood volume and so
           could be small in severely hypovolemic patients [39]…
           Pinsky et al. Critical Care 2005, 9:566-572

           Untimely measure of SV
           …Because the maximal hemodynamic effects of PLR occur within the first minute of leg
           elevation [43], it is important to assess these effects with a method that is able to track
           changes in cardiac output or stroke volume on a real-time basis.
           Marik et al. Annals of Intensive Care 2011, 1:1

           Maneuver technique
           …Jabot et al. [16] found significant differences in hemodynamic response to PLR
           performed by starting from supine versus semi recumbent position but in our analysis the
           reliability of PLR-cCO was proven to be independent from how the PLR maneuver was
           performed….
           Cavallaro F et a. Intensive Care Med (2010) 36:1475–1483
www.uscom.com.au                                              The Measure of Life

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Case Study - Adult - Passive Leg Raise

  • 1. Passive Leg Raise to test for fluid response www.uscom.com.au The Measure of Life
  • 2. Post Passive Leg Raise 19% increase www.uscom.com.au The Measure of Life
  • 3. Possible passive leg raising false negative tests Conditions of high intra-abdominal pressure …should be noted that intra-abdominal hypertension (intra-abdominal pressure > 16 mm Hg) impairs venous return and reduces the ability of PLR to detect fluid responsiveness [54]... Marik et al. Annals of Intensive Care 2011, 1:1 States of severe dehydration …the blood volume mobilized by leg raising is dependent on total blood volume and so could be small in severely hypovolemic patients [39]… Pinsky et al. Critical Care 2005, 9:566-572 Untimely measure of SV …Because the maximal hemodynamic effects of PLR occur within the first minute of leg elevation [43], it is important to assess these effects with a method that is able to track changes in cardiac output or stroke volume on a real-time basis. Marik et al. Annals of Intensive Care 2011, 1:1 Maneuver technique …Jabot et al. [16] found significant differences in hemodynamic response to PLR performed by starting from supine versus semi recumbent position but in our analysis the reliability of PLR-cCO was proven to be independent from how the PLR maneuver was performed…. Cavallaro F et a. Intensive Care Med (2010) 36:1475–1483 www.uscom.com.au The Measure of Life

Editor's Notes

  1. Where possible a Passive Leg Raise (PLR) is a safe method to determine how fluid responsive a patient might be and therefore how safe it is too increase fluids.Low SV - 79Low SVI – 36 (Typical 35-65)SVR - 1787 = consistent with hypovolemiaSVRI - 3931HR - > 60Low – Normal Vpk - 1.1Low CO - 4.8Low CI - 2.2 = Hypovolemia
  2. SV 79->94 = 19% increaseNormal SV 94Normal SVI – 44Normal SVR 1196HR > 60Normal Vpk 1.3Normal CO 7.1Normal CI 3.3
  3. When PLR test with USCOM is positive it has a 91% Positive predictive value.Although when negative, there is a high False negative rate.Causes of False negative are shown here.Therefore when PLR is negative, confirm with other input such as SVI, SVV if ventilated.