This document summarizes three patient case presentations from a virtual molecular tumor board meeting. It discusses the histories, test results, relevant gene mutations, and potential treatment options for 1) a gastric tumor with FBXW7 and GNAS mutations, 2) a cholangiocarcinoma with a RET mutation, and 3) an EGFR-mutated non-small cell lung cancer. Standard therapies, clinical trial options, and molecular pathways are reviewed for each case.