This document provides a guide for healthcare facilities to increase colonoscopy screening rates for colorectal cancer prevention. It discusses how colonoscopy is the most effective screening tool, yet rates remain low, especially among minority groups. The goal is to double colonoscopy screening in New York City over 5 years by providing best practices and tools. Section I outlines 5 best practices clinics can adopt, such as promoting routine referrals for those 50+, direct referrals, and reducing no-shows. Section II provides clinician tools on bowel prep, sedation, and follow-up. Section III offers administrative resources like CPT codes, referral forms, and a patient navigation program description.