This document discusses the correlation between donor-specific antibody (DSA) binding to complement component C3d and graft failure in kidney transplant patients. It notes that C4d deposition and detection of C3d using Luminex technology can help identify antibody-mediated rejection (AMR).

1. 1 All Content © 2014 Immucor, Inc.
The ability of DSA to bind C3d strongly correlates
with graft failure
C4d deposition on the graft Presence of C3d by Luminex
Sicard A. et al. J Am Soc Nephrol 2015, 26(2):457-67
AMR