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BRAINWARE UNIVERSITY
Presented by :
Sourav Chakraborty
BWU/BSO/22/089
Ocular Anatomy
Presented to :
Nice Ghosh
UVEAL TRACT
Uvea known as middle
vascular coat of eyeball.
Anterior to posterior it can
be divided into three parts---
 Iris
Ciliary body
Choroid
Note– Uvea is a Greek
word meaning Grapes.
IRIS
 Anterior part of the uveal tract.
 Forms diaphragm like structure in front of lens.
 Center of iris has an 3-4 mm aperture called Pupil.
 At periphery it is attached to the anterior surface of ciliary
body.
 Divides the space between the cornea and lens into anterior
and posterior chamber.
TOPOGRAPHY OF IRIS
 Average diameter of the iris is 10 to 11 mm.
 The thickness of iris root is approximately 0.5
mm.
 It is thickest at collarette, which is located
approximately 1.5 mm from the pupillary
margin
 It is thinnest at iris root, the part of iris which
joins with the ciliary body
EMBRYOLOGY
 Both layer of epithelium is derived from marginal region of
optic cup. (Neuroectoderm)
 Sphincter and dilator pupillae muscle derived from anterior
epithelium . (Neuroectoderm)
 Stroma and vessels developed from vascular mesoderm
present anterior to optic cup.
MACROSCOPIC APPEARANCE
 Anterior surface —
Divided into cilary and pupillary zone by zigzag line called
collarette.
It is the thickest region of the iris which lies about 2 mm
from the pupil margin.
Cilliary zone-
It extend from the collarette to iris root.
There are some depressions or pit arranged in
rows present in this area known as crypts.
Crypts are found in two locations. Those
present near collarette are relatively larger and
known as Fuchs’s crypt and few are seen in
periphery of the iris
Pupillary Zone-
It lies between the collarette and pigmented
pupilary frill
It is 1.6 mm wide,relatively smooth and flat.
POSTERIOR SURFACE
Posterior surface of
the iris is much more
uniform.
Posterior surface of
the iris is darker than
the anterior surface and
shows numerous radial
contraction folds.
MICROSCOPIC STRUCTURE
Microscopically iris consist of four layers
1 Anterior limiting membrane.
2 Iris stroma
3 Anterior epithelium layer
4 Posterior pigmented epithelium layer.
1.Anterior limiting layer :
 It lines the iris and is the anterior most condensations of iris
stroma.
 The layer consist of mainly fibroblasts and melanocytes.
 Previously, this layer is known as ENDOTHELIAL LAYER .
 This layer is mainly responsible for the colouring action of iris.
2. Iris stroma:
Iris stroma forms the main bulk of iris tissue and contains
sphincter pupillae, dilator pupillae muscles, vessels and nerves.
3. Anterior epithelium layer :
It is the anterior continuation of the pigmented epithelium of
retina and ciliary body.
4. Posterior pigmented epithelium layer-
Anterior continuation of the non- pigmented epithelium of the ciliary body
and the sensory retina
CILIARY BODY
 It is the anterior portion of the uveal tract , which is
located b/w the iris and the choroid.
 middle part of vascular coat of eyeball.
 Triangular in shape.
 Inner side of triangle is divided into two parts.
 The anterior portion - pars plicata
 The posterior portion-pars plana
 The outer side of triangle lies against the
sclera.
 composed of muscles , vessels and epithelium.
EMBRYOLOGY
 Both epithelial layer of ciliary body develop from
the anterior part of the two layers of optic
cup.(neuroectoderm)
 Stroma of the ciliary body , ciliary muscle and blood
vessels are developed from the vascular layer of
mesenchyme surrounding the optic cup.
MICROSCOPIC STRUCTURE
🞭 Microscopically ciliary body consist of five layers.
o Supraciliary lamina.
o Stroma.
o Layer of pigmented epithelium.
o Layer of non pigmented epithelium.
o Internal limiting membrane.
 Supraciliary lamina –
 outermost condensed part of the stroma consist of pigmented
collagen fibres.
 Anteriorly become continues with the anterior limiting
membrane of iris.
 posteriorly, it is the continuation of the suprachoroidal lamina.
 Stroma—
 Consist of connective tissue of collagen and fibroblast.
 Ciliary muscle, vessels, nerves and cells are embedded in
stroma.
 Layer of pigmented epithelium-
 Forward continuation of the retinal pigmented epithelium.
 Anteriorly become continues with the anterior pigmented
epithelium of iris.
 Layer of non pigmented epithelium-
 Forward continuation of sensory retina.
 Continues anteriorly with the posteriorly pigmented
epithelium of iris.
 Internal limiting membrane-
 Forward continuation of the internal limiting membrane of
the retina.
 Lines the non-pigmented epithelial layer.
CILIARY PROCESS
🞭 Finger like projection from the pars plicata part of the
ciliary body.
🞭 They are white in color
🞭 Process is lined by two layer of epithelial cell .
🞭 It contain blood vessels and loose connective tissue
🞭 these process are the site of aqueous production.
🞭 Each process is about 2 mm long and 0.5 mm in
diameter.
🞭 They are about 70 to 80 in numbers.
CILIARY MUSCLE
 Occupies most of the outer part of the ciliary body.
 These are non striated muscle having three parts
1. Meridional fibers- Help in aqueous outflow.
2. Circular fibers
3. Oblique fibers
- Help in accommodation.
- Help in Aqueous outflow.
 Ciliary muscle is supplied by parasympathetic fibers
through the short ciliary nerves.
Action- Main action is to slacken the suspensory
ligament of the lens and thus help in
accommodation.
EMBRYOLOGY
 Mainly derived from the inner vascular layer
of the mesenchyme that surrounds the optic
cup
 Melanocytes of choroid originate from the
neural crest.
MICROSCOPIC STRUCTURE OF
CHOROID
 Choroid consist of four layers.
 Suprachoroidal lamina.
 Stroma.
 Choriocapillaris.
 Bruch's membrane.
1.Suprachoroid lamina (lamina fusca):
Thin membrane of condensed collagen fibers,
melanocytes and fibroblast.
It consist of potential space between sclera and choroid
known as supra choroidal space.
 The potential space contains the long posterior ciliary arteries
and nerves.
2. Choroidal stroma:
Consist of loose collagenous tissue with some elastic and
reticular fibers.
 Contain pigmented cells and plasma cells.
 It forms the main bulk of the choroid.
It consist of two types of vessels Medium vessels and large
vessels
 3. Layer of Choriocapillaris
 It nourishes the pigmented epithelium and outer layer of sensory
retina.
 Choriocapillaries contain a basement membrane.
 Receive blood from medium and large vessels of stroma.
 The capillary walls are fenestrated and contains pericytes
4. Bruch's membrane:
 innermost layer of choroid having thickness 2-4 mm.
 Multilayered structure lies between the choriocapillaris and
pigmented epithelium of retina.
 It consist of five layers:-
• Basement membraneof retinal pigmentedepithelium
• Inner collagenfibers
• Middleelasticfibers
• Outer collagenfibers
BLOOD SUPPLY OF UVEAL TRACT
🞭 The uveal tract is supplied by three sets of artery.
 Short posterior ciliary artery- Arises as two trunks from the
ophthalmic artery .
 It pierce the sclera around the optic nerve and supply the
choroid in a segmental manner.
 Long posterior ciliary artery-- two in number nasal and temporal
.
 Pierce the sclera obliquely on medial and lateral side of the
optic nerve and supply the ciliary body.
 Anterior ciliary artery– Derived from muscular branches of
ophthalmic artery.
 7 in numbers– 2 each of superior, medial, inferior rectus
muscle and one from lateral rectus muscle
 these artery gives branches to sclera , limbus and conjunctiva.
NERVE SUPPLY
 The iris receives its sensory and autonomic
nerve supply from the long and short ciliary
nerves.
 The long ciliary nerves are branches of the
nasociliary branch of the ophthalmic division
of the trigeminal nerve. These fibers
innervate the dilator pupillae.
 • The short ciliary nerves arise from the
ciliary ganglion and contain postganglionic
parasympathetic nerve fibers.
 The parasympathetic innervates the
sphincter pupillae.
 The choroid is innervated by the long and
short ciliary nerves.
 The long ciliary nerves are branches of the
nasociliary nerves, a branch of the
ophthalmic division of the trigeminal nerve.
(sensory & parasympathetic) –
 The short ciliary nerves arise from the ciliary
ganglion and carry parasympathetic fibers
and sympathetic fibers.
 The ciliary muscle is innervated by the
postganglionic parasympathetic fibers
derived from the oculomotor nerve; The nerve
fibers reach the muscle via the short ciliary
nerves.
UVEITIS
 Also known as Iridocyclitis.
 Inflammation of uveal tissue.
 Common cause of blindness.
 Associated with systematic autoimmune disease.
 Symptoms and signs
 Ciliary flush
 Burning of the eye
 Redness of the eye
 Blurred vision
Photophobia or sensitivity to
Light.
 Irregular pupil.
ENDOPHTHALMITIS
 It is an inflammation of the internal coats of the eyeball
 It is a possible complication of all intraocular surgeries,
particularly cataract surgery, with possible loss of vision and the eye
itself.
 CAUSES-
 Bacterial and fungal infection
 penetrating trauma
 allergic reaction
 Symptoms-
 severe pain
 loss of vision
 redness of the conjunctiva
 Photophobia
 Management-
 Topical therapy
 Subconjunctival infections
 Intravitreal injection.
PANOPHTHALMITIS
 Inflammation of the whole eyeball including tenon’s
capsule.
 Eyeball is filled with pus
 Uveal tract is infiltrated with inflammatory cells like WBC.
 Symptoms-
 Ocular pain
 Headache
 Complete loss of vision
 Swelling of eyes.
 Management-
 anti-inflammatory and analgesics should be started
immediately.
 use broad spectrum of antibodies to prevent further
spread of infection.
• Refarence:-
 A.K.Khurana, Anatomy & physiology of the eye
 Referance of Internet
BWU-BSO-22-089.pptx

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BWU-BSO-22-089.pptx

  • 1. BRAINWARE UNIVERSITY Presented by : Sourav Chakraborty BWU/BSO/22/089 Ocular Anatomy Presented to : Nice Ghosh
  • 2. UVEAL TRACT Uvea known as middle vascular coat of eyeball. Anterior to posterior it can be divided into three parts---  Iris Ciliary body Choroid Note– Uvea is a Greek word meaning Grapes.
  • 3. IRIS  Anterior part of the uveal tract.  Forms diaphragm like structure in front of lens.  Center of iris has an 3-4 mm aperture called Pupil.  At periphery it is attached to the anterior surface of ciliary body.  Divides the space between the cornea and lens into anterior and posterior chamber.
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  • 5. TOPOGRAPHY OF IRIS  Average diameter of the iris is 10 to 11 mm.  The thickness of iris root is approximately 0.5 mm.  It is thickest at collarette, which is located approximately 1.5 mm from the pupillary margin  It is thinnest at iris root, the part of iris which joins with the ciliary body
  • 6. EMBRYOLOGY  Both layer of epithelium is derived from marginal region of optic cup. (Neuroectoderm)  Sphincter and dilator pupillae muscle derived from anterior epithelium . (Neuroectoderm)  Stroma and vessels developed from vascular mesoderm present anterior to optic cup.
  • 7. MACROSCOPIC APPEARANCE  Anterior surface — Divided into cilary and pupillary zone by zigzag line called collarette. It is the thickest region of the iris which lies about 2 mm from the pupil margin.
  • 8. Cilliary zone- It extend from the collarette to iris root. There are some depressions or pit arranged in rows present in this area known as crypts. Crypts are found in two locations. Those present near collarette are relatively larger and known as Fuchs’s crypt and few are seen in periphery of the iris Pupillary Zone- It lies between the collarette and pigmented pupilary frill It is 1.6 mm wide,relatively smooth and flat.
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  • 10. POSTERIOR SURFACE Posterior surface of the iris is much more uniform. Posterior surface of the iris is darker than the anterior surface and shows numerous radial contraction folds.
  • 11. MICROSCOPIC STRUCTURE Microscopically iris consist of four layers 1 Anterior limiting membrane. 2 Iris stroma 3 Anterior epithelium layer 4 Posterior pigmented epithelium layer.
  • 12. 1.Anterior limiting layer :  It lines the iris and is the anterior most condensations of iris stroma.  The layer consist of mainly fibroblasts and melanocytes.  Previously, this layer is known as ENDOTHELIAL LAYER .  This layer is mainly responsible for the colouring action of iris. 2. Iris stroma: Iris stroma forms the main bulk of iris tissue and contains sphincter pupillae, dilator pupillae muscles, vessels and nerves. 3. Anterior epithelium layer : It is the anterior continuation of the pigmented epithelium of retina and ciliary body. 4. Posterior pigmented epithelium layer- Anterior continuation of the non- pigmented epithelium of the ciliary body and the sensory retina
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  • 14. CILIARY BODY  It is the anterior portion of the uveal tract , which is located b/w the iris and the choroid.  middle part of vascular coat of eyeball.  Triangular in shape.  Inner side of triangle is divided into two parts.  The anterior portion - pars plicata  The posterior portion-pars plana  The outer side of triangle lies against the sclera.  composed of muscles , vessels and epithelium.
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  • 17. EMBRYOLOGY  Both epithelial layer of ciliary body develop from the anterior part of the two layers of optic cup.(neuroectoderm)  Stroma of the ciliary body , ciliary muscle and blood vessels are developed from the vascular layer of mesenchyme surrounding the optic cup.
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  • 19. MICROSCOPIC STRUCTURE 🞭 Microscopically ciliary body consist of five layers. o Supraciliary lamina. o Stroma. o Layer of pigmented epithelium. o Layer of non pigmented epithelium. o Internal limiting membrane.
  • 20.  Supraciliary lamina –  outermost condensed part of the stroma consist of pigmented collagen fibres.  Anteriorly become continues with the anterior limiting membrane of iris.  posteriorly, it is the continuation of the suprachoroidal lamina.  Stroma—  Consist of connective tissue of collagen and fibroblast.  Ciliary muscle, vessels, nerves and cells are embedded in stroma.  Layer of pigmented epithelium-  Forward continuation of the retinal pigmented epithelium.  Anteriorly become continues with the anterior pigmented epithelium of iris.
  • 21.  Layer of non pigmented epithelium-  Forward continuation of sensory retina.  Continues anteriorly with the posteriorly pigmented epithelium of iris.  Internal limiting membrane-  Forward continuation of the internal limiting membrane of the retina.  Lines the non-pigmented epithelial layer.
  • 22. CILIARY PROCESS 🞭 Finger like projection from the pars plicata part of the ciliary body. 🞭 They are white in color 🞭 Process is lined by two layer of epithelial cell . 🞭 It contain blood vessels and loose connective tissue 🞭 these process are the site of aqueous production. 🞭 Each process is about 2 mm long and 0.5 mm in diameter. 🞭 They are about 70 to 80 in numbers.
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  • 24. CILIARY MUSCLE  Occupies most of the outer part of the ciliary body.  These are non striated muscle having three parts 1. Meridional fibers- Help in aqueous outflow. 2. Circular fibers 3. Oblique fibers - Help in accommodation. - Help in Aqueous outflow.  Ciliary muscle is supplied by parasympathetic fibers through the short ciliary nerves. Action- Main action is to slacken the suspensory ligament of the lens and thus help in accommodation.
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  • 27. EMBRYOLOGY  Mainly derived from the inner vascular layer of the mesenchyme that surrounds the optic cup  Melanocytes of choroid originate from the neural crest.
  • 28. MICROSCOPIC STRUCTURE OF CHOROID  Choroid consist of four layers.  Suprachoroidal lamina.  Stroma.  Choriocapillaris.  Bruch's membrane.
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  • 30. 1.Suprachoroid lamina (lamina fusca): Thin membrane of condensed collagen fibers, melanocytes and fibroblast. It consist of potential space between sclera and choroid known as supra choroidal space.  The potential space contains the long posterior ciliary arteries and nerves. 2. Choroidal stroma: Consist of loose collagenous tissue with some elastic and reticular fibers.  Contain pigmented cells and plasma cells.  It forms the main bulk of the choroid. It consist of two types of vessels Medium vessels and large vessels
  • 31.  3. Layer of Choriocapillaris  It nourishes the pigmented epithelium and outer layer of sensory retina.  Choriocapillaries contain a basement membrane.  Receive blood from medium and large vessels of stroma.  The capillary walls are fenestrated and contains pericytes 4. Bruch's membrane:  innermost layer of choroid having thickness 2-4 mm.  Multilayered structure lies between the choriocapillaris and pigmented epithelium of retina.  It consist of five layers:- • Basement membraneof retinal pigmentedepithelium • Inner collagenfibers • Middleelasticfibers • Outer collagenfibers
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  • 33. BLOOD SUPPLY OF UVEAL TRACT 🞭 The uveal tract is supplied by three sets of artery.  Short posterior ciliary artery- Arises as two trunks from the ophthalmic artery .  It pierce the sclera around the optic nerve and supply the choroid in a segmental manner.  Long posterior ciliary artery-- two in number nasal and temporal .  Pierce the sclera obliquely on medial and lateral side of the optic nerve and supply the ciliary body.  Anterior ciliary artery– Derived from muscular branches of ophthalmic artery.  7 in numbers– 2 each of superior, medial, inferior rectus muscle and one from lateral rectus muscle  these artery gives branches to sclera , limbus and conjunctiva.
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  • 35. NERVE SUPPLY  The iris receives its sensory and autonomic nerve supply from the long and short ciliary nerves.  The long ciliary nerves are branches of the nasociliary branch of the ophthalmic division of the trigeminal nerve. These fibers innervate the dilator pupillae.  • The short ciliary nerves arise from the ciliary ganglion and contain postganglionic parasympathetic nerve fibers.  The parasympathetic innervates the sphincter pupillae.
  • 36.  The choroid is innervated by the long and short ciliary nerves.  The long ciliary nerves are branches of the nasociliary nerves, a branch of the ophthalmic division of the trigeminal nerve. (sensory & parasympathetic) –  The short ciliary nerves arise from the ciliary ganglion and carry parasympathetic fibers and sympathetic fibers.  The ciliary muscle is innervated by the postganglionic parasympathetic fibers derived from the oculomotor nerve; The nerve fibers reach the muscle via the short ciliary nerves.
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  • 38. UVEITIS  Also known as Iridocyclitis.  Inflammation of uveal tissue.  Common cause of blindness.  Associated with systematic autoimmune disease.  Symptoms and signs  Ciliary flush  Burning of the eye  Redness of the eye  Blurred vision Photophobia or sensitivity to Light.  Irregular pupil.
  • 39. ENDOPHTHALMITIS  It is an inflammation of the internal coats of the eyeball  It is a possible complication of all intraocular surgeries, particularly cataract surgery, with possible loss of vision and the eye itself.  CAUSES-  Bacterial and fungal infection  penetrating trauma  allergic reaction  Symptoms-  severe pain  loss of vision  redness of the conjunctiva  Photophobia  Management-  Topical therapy  Subconjunctival infections  Intravitreal injection.
  • 40. PANOPHTHALMITIS  Inflammation of the whole eyeball including tenon’s capsule.  Eyeball is filled with pus  Uveal tract is infiltrated with inflammatory cells like WBC.  Symptoms-  Ocular pain  Headache  Complete loss of vision  Swelling of eyes.  Management-  anti-inflammatory and analgesics should be started immediately.  use broad spectrum of antibodies to prevent further spread of infection.
  • 41. • Refarence:-  A.K.Khurana, Anatomy & physiology of the eye  Referance of Internet