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Biologia Molecular
1. Atomic Structure Discovered for a Sodium Channel That Generates Electrical Signals in Living Cells AND Biologists Identify New Strategy Used by Bacteria During Infection Laura Isabel Gómez Rivas Medicine Student Medellín, Colombia UPB 2011
4. INTRODUCTION Voltage-dependent sodium channels, regulate many physiological functions and multiple mutations cause diseases in them The bacterium have a strategy for infection , it was discovered how the bacterum modify healthy cells, the study was conducted using the Legionella Neumophila bacterium
5. Atomic Structure Discovered for a Sodium Channel That Generates Electrical Signals in Living Cells Science Daily July 13, 2011
6. Atomic Structure Discovered for a Sodium Channel That Generates Electrical Signals in Living Cells Science Daily July 13, 2011 Sodium channels are pores in the membranes of excitable cells such as brain nerve cells or beating heart cells that this emit electrical signals. Sodium channels are important molecules because they regulate a wide range of physiological activities.
7. Atomic Structure Discovered for a Sodium Channel That Generates Electrical Signals in Living Cells Science Daily July 13, 2011 Mutations in voltage-gated sodium channels underlie inherited forms of epilepsy, migraine headaches, heart rhythm disturbances, periodic paralysis, and some pain syndromes The symptoms of these disorders often stem from faulty electrical signals between cells. Some nerve toxins, such as scorpion stings or hazardous algal blooms, disrupt sodium channels
8. Atomic Structure Discovered for a Sodium Channel That Generates Electrical Signals in Living Cells Science Daily July 13, 2011 The researchers have already spotted intriguing molecular movement, such as rolling motions of some functional parts of the sodium channel molecule and their connectors. Know how form affects function in sodium channels could lead to many new ideas from scientists around the world on designing drugs to home in on critical areas of the sodium channel molecule. There is a lot of interest in drug design based on the structure of this molecule and its binding sites
9. OBSERVATION This news is a clear example of the rapid pace leading research to understand mechanisms of microbial functioning. I think this type of study, long-term can be significantly to the treatment of many diseases curable
10. Biologists Identify New Strategy Used by Bacteria During Infection Science Daily July 13, 2011
11. Biologists Identify New Strategy Used by Bacteria During Infection Science Daily july 13, 2011 At Purdue University identified a new way in which the bacteria hijack healthy cells during infection. That we know this could provide a target for new antibiotics.
12. Biologists Identify New Strategy Used by Bacteria During Infection Science Daily july 13, 2011 The Legionella pneumophila infection has Needs delivery of hundreds of proteins in host cells that alter various functions to convert the hostile natural for the bacterial replication, for this reason the bacterium was used to study. Legionella pneumophila
13. Biologists Identify New Strategy Used by Bacteria During Infection Science Daily july 13, 2011 The researchers found the enzyme that reverses or stops SIDD processes in the cell. The activity of this enzyme is successful because the pathogen knows how information is transmitted in our cells and amplify signals from some other blocks in order to evade the immune system and prevent the cells defend themselves, creating resistance. Enzyem acting on healthy cell
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15. MEDICAL UTILITY research that contribute to modern medicine as the new invention of drugs are very important and can revolutionize treatments to various diseases
16. MEDICAL UTILITY The bacterial infections are of great importance throughout the world because they are very frequent, discover some mechanisms to infect certain bacteria can reduce their impact and contribute to better treatments.
17. MEDICAL UTILITY When the science progresses, lengthen the years of people's lives, so also the progress should involve a healthy life
18. MEDICAL UTILITY The investigation is an important field in the medicine because it allows to quantify and to qualify variables and also it allows other actions for reaching the medicine, for that, studies like this helps to improve ways to treat diseases and health.