SlideShare a Scribd company logo
1 of 14
Ban on P VALUE
?End of days of inferential statistics
Null hypothesis
• RESEACHER GUESS OR IMAGINE AS
THERE IS NO DIFFERENCE IN THE
FREQUENCE OF THE OCCURRENCE OF
EVENT BETWEEN CONTROL AND
INTERVENED GROUP =NULL
Jerzy Neyman and Egon Pearson
• Type I error: Rejecting a null hypothesis when it's true
• Type II error : Accepting one when it's not
DOES IT MEAN what we mean?
Most scientists would look at his original P value of 0.01 and say that there was
just a 1% chance of his result being a false alarm. But they would be wrong.
The P value cannot say this: all it can do is summarize the data assuming a
specific null hypothesis. It cannot work backwards and make statements about
the underlying reality. That requires another piece of information: the odds that
a real effect was there in the first place.
USE OF “p”
P values are widely used in
science to test null hypotheses
EXAMPLE
In a medical study looking at smoking and cancer, the null
hypothesis could be that there is no link between the two. The
closer to zero the P value gets, the greater the chance the null
hypothesis is false; many researchers accept findings as ‘significant’
if the P value comes in at less than 0.05.
TEST OF TIME
•P values are slippery, and sometimes,
significant P values vanish when
experiments and statistical analyses are
repeated
CRITIC
“ T H E P V A L U E W A S N E V E
R M E A N T T O B E U S E D T H
E W A Y I T ’ S U S E D T O D A Y.”
NUMBERS GAME
Despite the criticisms, reform has been slow. “The basic framework of statistics has
been virtually unchanged since Fisher, Neyman and Pearson introduced it,” says
Goodman. John Campbell, a psychologist now at the University of Minnesota in
Minneapolis, bemoaned the issue in 1982, when he was editor of the Journal of Applied
Psychology: “It is almost impossible to drag authors away from their p-values, and the
more zeroes after the decimal point, the harder people cling to them”. In 1989, when
Kenneth Rothman of Boston University in Massachusetts started the journal
Epidemiology, he did his best to discourage P values in its pages. But he left the journal
in 2001, and P values have since made a resurgence.
it is government licence for alcohol
Ioannidis is currently mining the PubMed database for
insights into how authors across many fields are using P
values and other statistical evidence. “A cursory look at a
sample of recently published papers,” he says, “is
convincing that P values are still very, very popular”.
2ND OPENION
http://www.nature.com/news/scientific-
method-statistical-errors-1.14700
None can ever stop evolution

More Related Content

Similar to Ban on  P values

Clinical versus statistical prediction
Clinical versus statistical predictionClinical versus statistical prediction
Clinical versus statistical predictionPaulo fattori
 
Surrogate Science: How Fisher, Neyman-Pearson, and Bayes Were Transformed int...
Surrogate Science: How Fisher, Neyman-Pearson, and Bayes Were Transformed int...Surrogate Science: How Fisher, Neyman-Pearson, and Bayes Were Transformed int...
Surrogate Science: How Fisher, Neyman-Pearson, and Bayes Were Transformed int...jemille6
 
Commentary Kaufman
Commentary  KaufmanCommentary  Kaufman
Commentary KaufmanBsie
 
Bioethics lecture UMDNJ-RWJ Medical School: "Addressing the Morass at the Int...
Bioethics lecture UMDNJ-RWJ Medical School: "Addressing the Morass at the Int...Bioethics lecture UMDNJ-RWJ Medical School: "Addressing the Morass at the Int...
Bioethics lecture UMDNJ-RWJ Medical School: "Addressing the Morass at the Int...Gary Schwitzer
 
MIT Medical Evidence Bootcamp for Journalists 2012
MIT Medical Evidence Bootcamp for Journalists 2012MIT Medical Evidence Bootcamp for Journalists 2012
MIT Medical Evidence Bootcamp for Journalists 2012GarySchwitzer
 
Ledger k. challenging an assumption. minnesota medicine 2009
Ledger k. challenging an assumption. minnesota medicine 2009Ledger k. challenging an assumption. minnesota medicine 2009
Ledger k. challenging an assumption. minnesota medicine 2009Alison Stevens
 
Ledger K. Challenging An Assumption. Minnesota Medicine 2009
Ledger K. Challenging An Assumption. Minnesota Medicine 2009Ledger K. Challenging An Assumption. Minnesota Medicine 2009
Ledger K. Challenging An Assumption. Minnesota Medicine 2009alisonegypt
 
How journalists (and other mass media) often promote too much medicine
How journalists (and other mass media)  often promote too much medicineHow journalists (and other mass media)  often promote too much medicine
How journalists (and other mass media) often promote too much medicineGary Schwitzer
 
Believable Science
Believable ScienceBelievable Science
Believable Sciencetamsin.rose
 
Common Statistical Concerns in Clinical Trials
Common Statistical Concerns in Clinical TrialsCommon Statistical Concerns in Clinical Trials
Common Statistical Concerns in Clinical TrialsClin Plus
 
1. What are the science community’s two standards for considering .docx
1. What are the science community’s two standards for considering .docx1. What are the science community’s two standards for considering .docx
1. What are the science community’s two standards for considering .docxjeremylockett77
 
How to read a paper
How to read a paperHow to read a paper
How to read a paperfaheta
 
Debunk bullshit in statistics QN
Debunk bullshit in statistics QNDebunk bullshit in statistics QN
Debunk bullshit in statistics QNQuan Nguyen
 
MethodUnderstandingStatisticalSignificanceMatthew .docx
MethodUnderstandingStatisticalSignificanceMatthew .docxMethodUnderstandingStatisticalSignificanceMatthew .docx
MethodUnderstandingStatisticalSignificanceMatthew .docxARIV4
 
1 how you look in pictures tells a lot about you
1 how you look in pictures tells a lot about you1 how you look in pictures tells a lot about you
1 how you look in pictures tells a lot about youMy English
 

Similar to Ban on  P values (20)

Statistical significance
Statistical significanceStatistical significance
Statistical significance
 
Clinical versus statistical prediction
Clinical versus statistical predictionClinical versus statistical prediction
Clinical versus statistical prediction
 
Surrogate Science: How Fisher, Neyman-Pearson, and Bayes Were Transformed int...
Surrogate Science: How Fisher, Neyman-Pearson, and Bayes Were Transformed int...Surrogate Science: How Fisher, Neyman-Pearson, and Bayes Were Transformed int...
Surrogate Science: How Fisher, Neyman-Pearson, and Bayes Were Transformed int...
 
John Read, Placebo
John Read, PlaceboJohn Read, Placebo
John Read, Placebo
 
Reporting Results of Statistical Analysis
Reporting Results of Statistical Analysis Reporting Results of Statistical Analysis
Reporting Results of Statistical Analysis
 
Commentary Kaufman
Commentary  KaufmanCommentary  Kaufman
Commentary Kaufman
 
P-values in crisis
P-values in crisisP-values in crisis
P-values in crisis
 
Bioethics lecture UMDNJ-RWJ Medical School: "Addressing the Morass at the Int...
Bioethics lecture UMDNJ-RWJ Medical School: "Addressing the Morass at the Int...Bioethics lecture UMDNJ-RWJ Medical School: "Addressing the Morass at the Int...
Bioethics lecture UMDNJ-RWJ Medical School: "Addressing the Morass at the Int...
 
MIT Medical Evidence Bootcamp for Journalists 2012
MIT Medical Evidence Bootcamp for Journalists 2012MIT Medical Evidence Bootcamp for Journalists 2012
MIT Medical Evidence Bootcamp for Journalists 2012
 
Ledger k. challenging an assumption. minnesota medicine 2009
Ledger k. challenging an assumption. minnesota medicine 2009Ledger k. challenging an assumption. minnesota medicine 2009
Ledger k. challenging an assumption. minnesota medicine 2009
 
Ledger K. Challenging An Assumption. Minnesota Medicine 2009
Ledger K. Challenging An Assumption. Minnesota Medicine 2009Ledger K. Challenging An Assumption. Minnesota Medicine 2009
Ledger K. Challenging An Assumption. Minnesota Medicine 2009
 
How journalists (and other mass media) often promote too much medicine
How journalists (and other mass media)  often promote too much medicineHow journalists (and other mass media)  often promote too much medicine
How journalists (and other mass media) often promote too much medicine
 
Believable Science
Believable ScienceBelievable Science
Believable Science
 
Common Statistical Concerns in Clinical Trials
Common Statistical Concerns in Clinical TrialsCommon Statistical Concerns in Clinical Trials
Common Statistical Concerns in Clinical Trials
 
The Bruening Case
The Bruening CaseThe Bruening Case
The Bruening Case
 
1. What are the science community’s two standards for considering .docx
1. What are the science community’s two standards for considering .docx1. What are the science community’s two standards for considering .docx
1. What are the science community’s two standards for considering .docx
 
How to read a paper
How to read a paperHow to read a paper
How to read a paper
 
Debunk bullshit in statistics QN
Debunk bullshit in statistics QNDebunk bullshit in statistics QN
Debunk bullshit in statistics QN
 
MethodUnderstandingStatisticalSignificanceMatthew .docx
MethodUnderstandingStatisticalSignificanceMatthew .docxMethodUnderstandingStatisticalSignificanceMatthew .docx
MethodUnderstandingStatisticalSignificanceMatthew .docx
 
1 how you look in pictures tells a lot about you
1 how you look in pictures tells a lot about you1 how you look in pictures tells a lot about you
1 how you look in pictures tells a lot about you
 

More from Ramachandra Barik

Intensive care of congenital heart disease.pptx
Intensive care of congenital heart disease.pptxIntensive care of congenital heart disease.pptx
Intensive care of congenital heart disease.pptxRamachandra Barik
 
Management of Hypetension.pptx
Management of Hypetension.pptxManagement of Hypetension.pptx
Management of Hypetension.pptxRamachandra Barik
 
CRISPR and cardiovascular diseases.pdf
CRISPR and cardiovascular diseases.pdfCRISPR and cardiovascular diseases.pdf
CRISPR and cardiovascular diseases.pdfRamachandra Barik
 
Pacemaker Pocket Infection After Splenectomy
Pacemaker Pocket Infection After SplenectomyPacemaker Pocket Infection After Splenectomy
Pacemaker Pocket Infection After SplenectomyRamachandra Barik
 
A Case of Device Closure of an Eccentric Atrial Septal Defect Using a Large D...
A Case of Device Closure of an Eccentric Atrial Septal Defect Using a Large D...A Case of Device Closure of an Eccentric Atrial Septal Defect Using a Large D...
A Case of Device Closure of an Eccentric Atrial Septal Defect Using a Large D...Ramachandra Barik
 
Trio of Rheumatic Mitral Stenosis, Right Posterior Septal Accessory Pathway a...
Trio of Rheumatic Mitral Stenosis, Right Posterior Septal Accessory Pathway a...Trio of Rheumatic Mitral Stenosis, Right Posterior Septal Accessory Pathway a...
Trio of Rheumatic Mitral Stenosis, Right Posterior Septal Accessory Pathway a...Ramachandra Barik
 
Anticoagulation therapy during pregnancy
Anticoagulation therapy during pregnancyAnticoagulation therapy during pregnancy
Anticoagulation therapy during pregnancyRamachandra Barik
 
Intracoronary optical coherence tomography
Intracoronary optical coherence tomographyIntracoronary optical coherence tomography
Intracoronary optical coherence tomographyRamachandra Barik
 
A roadmap for the human development
A roadmap for the human developmentA roadmap for the human development
A roadmap for the human developmentRamachandra Barik
 
Left ventricular false tendons
Left ventricular false tendonsLeft ventricular false tendons
Left ventricular false tendonsRamachandra Barik
 

More from Ramachandra Barik (20)

Willens's syndrome.pptx
Willens's syndrome.pptxWillens's syndrome.pptx
Willens's syndrome.pptx
 
Intensive care of congenital heart disease.pptx
Intensive care of congenital heart disease.pptxIntensive care of congenital heart disease.pptx
Intensive care of congenital heart disease.pptx
 
Management of Hypetension.pptx
Management of Hypetension.pptxManagement of Hypetension.pptx
Management of Hypetension.pptx
 
CRISPR and cardiovascular diseases.pdf
CRISPR and cardiovascular diseases.pdfCRISPR and cardiovascular diseases.pdf
CRISPR and cardiovascular diseases.pdf
 
Pacemaker Pocket Infection After Splenectomy
Pacemaker Pocket Infection After SplenectomyPacemaker Pocket Infection After Splenectomy
Pacemaker Pocket Infection After Splenectomy
 
Piccolo Duct Occluder.pdf
Piccolo Duct Occluder.pdfPiccolo Duct Occluder.pdf
Piccolo Duct Occluder.pdf
 
MISPLACED ECG LEADS.pptx
MISPLACED ECG LEADS.pptxMISPLACED ECG LEADS.pptx
MISPLACED ECG LEADS.pptx
 
A Case of Device Closure of an Eccentric Atrial Septal Defect Using a Large D...
A Case of Device Closure of an Eccentric Atrial Septal Defect Using a Large D...A Case of Device Closure of an Eccentric Atrial Septal Defect Using a Large D...
A Case of Device Closure of an Eccentric Atrial Septal Defect Using a Large D...
 
Arrythmia-IV.pptx
Arrythmia-IV.pptxArrythmia-IV.pptx
Arrythmia-IV.pptx
 
Arrythmia-III.pptx
Arrythmia-III.pptxArrythmia-III.pptx
Arrythmia-III.pptx
 
Arrythmia-II.pptx
Arrythmia-II.pptxArrythmia-II.pptx
Arrythmia-II.pptx
 
Arrythmia-I.pptx
Arrythmia-I.pptxArrythmia-I.pptx
Arrythmia-I.pptx
 
Trio of Rheumatic Mitral Stenosis, Right Posterior Septal Accessory Pathway a...
Trio of Rheumatic Mitral Stenosis, Right Posterior Septal Accessory Pathway a...Trio of Rheumatic Mitral Stenosis, Right Posterior Septal Accessory Pathway a...
Trio of Rheumatic Mitral Stenosis, Right Posterior Septal Accessory Pathway a...
 
Anticoagulation therapy during pregnancy
Anticoagulation therapy during pregnancyAnticoagulation therapy during pregnancy
Anticoagulation therapy during pregnancy
 
Coronary guidewire
Coronary guidewireCoronary guidewire
Coronary guidewire
 
Intracoronary optical coherence tomography
Intracoronary optical coherence tomographyIntracoronary optical coherence tomography
Intracoronary optical coherence tomography
 
Brugada syndrome
Brugada syndromeBrugada syndrome
Brugada syndrome
 
A roadmap for the human development
A roadmap for the human developmentA roadmap for the human development
A roadmap for the human development
 
Intra aortic balloon pump
Intra aortic balloon pumpIntra aortic balloon pump
Intra aortic balloon pump
 
Left ventricular false tendons
Left ventricular false tendonsLeft ventricular false tendons
Left ventricular false tendons
 

Ban on  P values

  • 1. Ban on P VALUE ?End of days of inferential statistics
  • 2.
  • 3. Null hypothesis • RESEACHER GUESS OR IMAGINE AS THERE IS NO DIFFERENCE IN THE FREQUENCE OF THE OCCURRENCE OF EVENT BETWEEN CONTROL AND INTERVENED GROUP =NULL
  • 4. Jerzy Neyman and Egon Pearson • Type I error: Rejecting a null hypothesis when it's true • Type II error : Accepting one when it's not
  • 5.
  • 6. DOES IT MEAN what we mean? Most scientists would look at his original P value of 0.01 and say that there was just a 1% chance of his result being a false alarm. But they would be wrong. The P value cannot say this: all it can do is summarize the data assuming a specific null hypothesis. It cannot work backwards and make statements about the underlying reality. That requires another piece of information: the odds that a real effect was there in the first place.
  • 7. USE OF “p” P values are widely used in science to test null hypotheses
  • 8. EXAMPLE In a medical study looking at smoking and cancer, the null hypothesis could be that there is no link between the two. The closer to zero the P value gets, the greater the chance the null hypothesis is false; many researchers accept findings as ‘significant’ if the P value comes in at less than 0.05.
  • 9. TEST OF TIME •P values are slippery, and sometimes, significant P values vanish when experiments and statistical analyses are repeated
  • 10. CRITIC “ T H E P V A L U E W A S N E V E R M E A N T T O B E U S E D T H E W A Y I T ’ S U S E D T O D A Y.”
  • 11. NUMBERS GAME Despite the criticisms, reform has been slow. “The basic framework of statistics has been virtually unchanged since Fisher, Neyman and Pearson introduced it,” says Goodman. John Campbell, a psychologist now at the University of Minnesota in Minneapolis, bemoaned the issue in 1982, when he was editor of the Journal of Applied Psychology: “It is almost impossible to drag authors away from their p-values, and the more zeroes after the decimal point, the harder people cling to them”. In 1989, when Kenneth Rothman of Boston University in Massachusetts started the journal Epidemiology, he did his best to discourage P values in its pages. But he left the journal in 2001, and P values have since made a resurgence.
  • 12. it is government licence for alcohol Ioannidis is currently mining the PubMed database for insights into how authors across many fields are using P values and other statistical evidence. “A cursory look at a sample of recently published papers,” he says, “is convincing that P values are still very, very popular”.
  • 14. None can ever stop evolution
  • 15. Holi 2015 in my place