This certificate of analysis from Shandong Octagon Chemicals Limited summarizes the results of quality testing of Avanafil batch number 20200301. The tests show the white powder conforms to enterprise standards for appearance, solubility, identification, heavy metals, related substances, loss on drying, and purity. The certificate concludes the batch meets all requirements and should be stored in a well-closed container at ambient temperature.

1. SHANDONG OCTAGON CHEMICALS LIMITED
CERTIFICATE OF ANALYSIS
TEL:0086-13071891945 FAX:0086-0535-6715688
Address: Rm 528, Building 2, No. 300-2, Changjiang Rd, YEDA, YanTai City,
ShanDong Province, China sales@octagonchem.com
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Product name Avanafil (Cas 330784-47-9)
Batch No. 20200301 Mfg. date 2020.03.04
Rep. Date 2020.03.09 Exp. date 2022.03.03
Packaging 1kg/Tin Batch Size 1.2kg
Test Items Standards: Enterprise Results
Appearance White or almost white crystalline powder White powder
Solubility
Practically insoluble in water, slightly soluble
in ethanol
conforms
Identification NMR/LC-MS/HPLC Conforms
Heavy Metals NMT10ppm <10ppm
Related
Substances(HPLC)
Single Impurity:NMT0.1%
Total impurities:NMT0.5%
0.07%
0.16%
Loss on drying NMT0.5% 0.31%
Purity NLT99.5% 99.77%
Conclusion It meets the requirements of Enterprise Standards
Storage Store in a well-closed container at ambient temperature
Prepared by: LI Reviewed by: WEI Released by:Zhang