Avanafil is a PDE5 inhibitor approved for treating erectile dysfunction, with FDA approval in 2012 and EMA approval in 2013. The document lists several leading avanafil API manufacturers in India, including Akhil Healthcare Pvt Ltd, Aarambh Life Science, and Msn Laboratories, highlighting their compliance with GMP standards and commitment to quality. It encourages potential investors to consider these manufacturers for profitable opportunities in the pharmaceutical market.