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                                                                            Stress Management and Biofeedback
                                                                                        Workshop
                                                                            Electro-
                                                                            Electro-dermal Activity (EDA) Physiology

       Sweat Gland Physiology




                                                                                   By: Dr. Ernesto Sh. Korenman, July/2008
                                                                                                                 July/2008
                                           Dr. Ernesto Sh. Korenman, 2008




                                                                       4                                                                        3

            Sweat Glands                                                                           Skin
                           •   Glands secrete 99 % water with
                               dissolved salts, traces of ammonia,
                               and other metabolic by-products.
                                                     by-

                           •   Can collectively produce up to 7-8
                               liters a day.                                                                Outermost Layer: Epidermis
                           •   Humans contain about 2.5 million
                               sweat glands in our body.                                                    Middle Layer: Dermis



                                                                                                            Deepest Layer: Hypodermis


                                                                                                        Blood Vessels

                                                                                                   Sweat Gland
                                                                            Neural innervations
                                           Dr. Ernesto Sh. Korenman, 2008                                           Dr. Ernesto Sh. Korenman, 2008




                                                                       6                                                                        5


 Control of Eccrine Sweat Glands                                                        Sweat Glands: types

• Activation is controlled directly by the                                  • One type of sweat gland occurs in the palms,
  Sympathetic Division of the Autonomic Nervous                               soles, forehead, and armpits
  System                                                                       › Control body temperature
                                                                               › Function in cold sweats = responses made
                                                                                 when you are frightened, nervous or
• Paradoxically receive primarily sympathetic                                    embarrassed
  cholinergic fibers (Acetylcholine releasing)

                                                                            • Other sweat glands occur on other body
                                                                              surfaces

                                           Dr. Ernesto Sh. Korenman, 2008                                           Dr. Ernesto Sh. Korenman, 2008




                                                                                                                                                     1
8                                                                                                     7


                                                                    Skin Conductance and sweat

                                                                                                                 • Skin conductance
                                                                                                                   begins to change
                                                                                                                   before moisture
        Emotional Sweating                                                                                         level

                                                                                                                 • As duct fills with
                                                                                                                   sweat, skin
                                                                                                                   conductance
                                                                                                                   increases
                                                               Sweat gland

                              Dr. Ernesto Sh. Korenman, 2008                                                                        Dr. Ernesto Sh. Korenman, 2008




                                                         10                                                                                                     9
Sweat Gland response to stressing sound                        Sweat-
                                                               Sweat-emotion link: the Limbic System
                                                                                       Thalamus             Cortex

                                                                                                                     Hyppocampus
                       Threatening Sound
                                                                                                                        Amygdala


                           Thalamus

                        Auditory Cortex

                                                                                                                     Hypothalamus
                         Limbic System                                    Cerebellum
                                                                                                  Medulla


                                                               • Limbic System activates the sweating pathway controlled by
                         Hypothalamus                            the Hypothalamus.
                                                               • Affected by, and responds to, emotional stimulus, such as
                      Sweat Gland response                       emotionally charged questions
                              Dr. Ernesto Sh. Korenman, 2008                                                                        Dr. Ernesto Sh. Korenman, 2008




                                                         12                                                                                                    11

            EDA electrodes



                                                                     Electrodermal Activity (EDA)
                                                                              Recording




                              Dr. Ernesto Sh. Korenman, 2008                                                                        Dr. Ernesto Sh. Korenman, 2008




                                                                                                                                                                     2
14                                                                                        13

Sweat gland and skin conductance                                           What is skin conductance?




                                                                                  Current (I)
                                                                                                  • Resistance R=V/ I (Ohms)
                                                                                                               R=
                                                             Battery
                                                                                                  • Conductance C = 1/ R
                                                                               Voltage (V)          (mho or Siemens)
                            Dr. Ernesto Sh. Korenman, 2008                                                            Dr. Ernesto Sh. Korenman, 2008




                                                       16                                                                                        15
Skin conductance/resistance units                                                     Sweat and EDA
                                                             • Phasic skin conduction response (greater conductance) occurs due to filling
                                                               of the sweat ducts in the epidermis and the constant expulsion of fluids from
                                                               the sweat pores


                                                             • Recovery to tonic levels of skin conductance is attributed to deposition of
                                                               moisture on the skin or re-absorption of fluids by the sweat glands
                                                                                       re-


                                                             • Amount of sweat delivered to the ducts and number of sweat glands that
                                                               are activated influence the amplitude of the conductance response


                                                             • Glands on the palmar and plantar surface have been recognized as
                                                               responding to emotional stimuli, with the remainder responding to thermal
                                                               changes


                            Dr. Ernesto Sh. Korenman, 2008                                                            Dr. Ernesto Sh. Korenman, 2008




                                                       18                                                                                        17

Quantification of EDA response (EDR)                                      Skin conductance response
                        - Latency

                        - Amplitude

                        -Recovery
                                                                                                       • Skin becomes a better
                                                                                                         conductor of electricity
                                                                                                         when external stimuli
                                                                                                         are presented




                                                                   Stimulus

                            Dr. Ernesto Sh. Korenman, 2008                                                            Dr. Ernesto Sh. Korenman, 2008




                                                                                                                                                       3
20                                                                                  19

                         Types of real SCL graph                                                                                 SCL graph

                                                                                                                                                         Relaxing



                                                                                                                                                         Cumulated
                                                                                                                                                         stimuli



                   Steady                                        Labile                                                                                  Recovery
                                                                                                                                                         after stimuli

                                                                 Dr. Ernesto Sh. Korenman, 2008                                                      Dr. Ernesto Sh. Korenman, 2008




                                                                                            22                                                                                  21

        Respiration artifact detection                                                            Specific (Sp) vs. non-specific response
                                                                                                                    non-


                                                                                                             Specific Non                                Specific
                                   Non                  Specific                                                      Specific
                                   Specific
                                                                                                                                      Non
                                                                                                                                      Specific


                                                                                                         TW=Time Window




                          Inhale              Inhale

                                                                                                  Stimulus                                Stimulus

                                                                 Dr. Ernesto Sh. Korenman, 2008                                                      Dr. Ernesto Sh. Korenman, 2008




                                                                                            24                                                                                  23

             Habituation of SCR to tone                                                                           SCR to fearful music
                                           =Tone
                    3                                             Run1
                   1.5

                    0
Skin Conductance
  Response (µS)
           (µ




                    3                                             Run2
                   1.5

                    0


                    3                                             Run3
                   1.5

                    0

                          10          50           90      130
                                        Time (sec)


                                                                 Dr. Ernesto Sh. Korenman, 2008                                                      Dr. Ernesto Sh. Korenman, 2008




                                                                                                                                                                                      4
25




The End




          Dr. Ernesto Sh. Korenman, 2008




                                           5

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Ar 2008b Eda Bfbk Physiol

  • 1. 2 Stress Management and Biofeedback Workshop Electro- Electro-dermal Activity (EDA) Physiology Sweat Gland Physiology By: Dr. Ernesto Sh. Korenman, July/2008 July/2008 Dr. Ernesto Sh. Korenman, 2008 4 3 Sweat Glands Skin • Glands secrete 99 % water with dissolved salts, traces of ammonia, and other metabolic by-products. by- • Can collectively produce up to 7-8 liters a day. Outermost Layer: Epidermis • Humans contain about 2.5 million sweat glands in our body. Middle Layer: Dermis Deepest Layer: Hypodermis Blood Vessels Sweat Gland Neural innervations Dr. Ernesto Sh. Korenman, 2008 Dr. Ernesto Sh. Korenman, 2008 6 5 Control of Eccrine Sweat Glands Sweat Glands: types • Activation is controlled directly by the • One type of sweat gland occurs in the palms, Sympathetic Division of the Autonomic Nervous soles, forehead, and armpits System › Control body temperature › Function in cold sweats = responses made when you are frightened, nervous or • Paradoxically receive primarily sympathetic embarrassed cholinergic fibers (Acetylcholine releasing) • Other sweat glands occur on other body surfaces Dr. Ernesto Sh. Korenman, 2008 Dr. Ernesto Sh. Korenman, 2008 1
  • 2. 8 7 Skin Conductance and sweat • Skin conductance begins to change before moisture Emotional Sweating level • As duct fills with sweat, skin conductance increases Sweat gland Dr. Ernesto Sh. Korenman, 2008 Dr. Ernesto Sh. Korenman, 2008 10 9 Sweat Gland response to stressing sound Sweat- Sweat-emotion link: the Limbic System Thalamus Cortex Hyppocampus Threatening Sound Amygdala Thalamus Auditory Cortex Hypothalamus Limbic System Cerebellum Medulla • Limbic System activates the sweating pathway controlled by Hypothalamus the Hypothalamus. • Affected by, and responds to, emotional stimulus, such as Sweat Gland response emotionally charged questions Dr. Ernesto Sh. Korenman, 2008 Dr. Ernesto Sh. Korenman, 2008 12 11 EDA electrodes Electrodermal Activity (EDA) Recording Dr. Ernesto Sh. Korenman, 2008 Dr. Ernesto Sh. Korenman, 2008 2
  • 3. 14 13 Sweat gland and skin conductance What is skin conductance? Current (I) • Resistance R=V/ I (Ohms) R= Battery • Conductance C = 1/ R Voltage (V) (mho or Siemens) Dr. Ernesto Sh. Korenman, 2008 Dr. Ernesto Sh. Korenman, 2008 16 15 Skin conductance/resistance units Sweat and EDA • Phasic skin conduction response (greater conductance) occurs due to filling of the sweat ducts in the epidermis and the constant expulsion of fluids from the sweat pores • Recovery to tonic levels of skin conductance is attributed to deposition of moisture on the skin or re-absorption of fluids by the sweat glands re- • Amount of sweat delivered to the ducts and number of sweat glands that are activated influence the amplitude of the conductance response • Glands on the palmar and plantar surface have been recognized as responding to emotional stimuli, with the remainder responding to thermal changes Dr. Ernesto Sh. Korenman, 2008 Dr. Ernesto Sh. Korenman, 2008 18 17 Quantification of EDA response (EDR) Skin conductance response - Latency - Amplitude -Recovery • Skin becomes a better conductor of electricity when external stimuli are presented Stimulus Dr. Ernesto Sh. Korenman, 2008 Dr. Ernesto Sh. Korenman, 2008 3
  • 4. 20 19 Types of real SCL graph SCL graph Relaxing Cumulated stimuli Steady Labile Recovery after stimuli Dr. Ernesto Sh. Korenman, 2008 Dr. Ernesto Sh. Korenman, 2008 22 21 Respiration artifact detection Specific (Sp) vs. non-specific response non- Specific Non Specific Non Specific Specific Specific Non Specific TW=Time Window Inhale Inhale Stimulus Stimulus Dr. Ernesto Sh. Korenman, 2008 Dr. Ernesto Sh. Korenman, 2008 24 23 Habituation of SCR to tone SCR to fearful music =Tone 3 Run1 1.5 0 Skin Conductance Response (µS) (µ 3 Run2 1.5 0 3 Run3 1.5 0 10 50 90 130 Time (sec) Dr. Ernesto Sh. Korenman, 2008 Dr. Ernesto Sh. Korenman, 2008 4
  • 5. 25 The End Dr. Ernesto Sh. Korenman, 2008 5