The document discusses the inheritance of a disease allele. It states that Mary's brother must have inherited the disease allele from their mother, who is a carrier. It then explains that for a carrier female, there is a 50% chance with each pregnancy that sons will inherit the disease allele and a 50% chance daughters will be carriers. Therefore, Mary has a 50% chance of being a carrier as well. It also notes that among Mary's children, one son would be a carrier, one son would have the disease, one daughter would be a carrier, and one daughter would be normal. Additionally, a carrier daughter could pass on the disease allele to her sons.
Answer(19)Mary’s parents are normal, therefore her brother must.pdf
1. Answer:
(19)
Mary’s parents are normal, therefore her brother must have got the disease allele from his mother
who is a carrier of the disease.
Parents
XY (Mary’s father) x XhX (Mary’s mother)
XhY (Mary’s brother)
For a carrier female, with each pregnancy there is a one in two (50%) chance her sons will
inherit the disease allele and a one in two (50%) chance her daughters will be carriers.
(a) Therefore Mary has 50% chance or ½ chance of being a carrier
(b) (c) and (d)
For a carrier female, with each pregnancy there is a one in two (50%) chance her sons will
inherit the disease allele and a one in two (50%) chance her daughters will be carriers.
Among mary’s sons, one will be a carrier and another will be hemophiliac
Among mary’s daughters, one will be a carrier and another will be normal
(e) the carrier daughter can transmit the disease to her son’s
Solution
Answer:
(19)
Mary’s parents are normal, therefore her brother must have got the disease allele from his mother
who is a carrier of the disease.
Parents
XY (Mary’s father) x XhX (Mary’s mother)
XhY (Mary’s brother)
For a carrier female, with each pregnancy there is a one in two (50%) chance her sons will
inherit the disease allele and a one in two (50%) chance her daughters will be carriers.
(a) Therefore Mary has 50% chance or ½ chance of being a carrier
(b) (c) and (d)
For a carrier female, with each pregnancy there is a one in two (50%) chance her sons will
inherit the disease allele and a one in two (50%) chance her daughters will be carriers.
Among mary’s sons, one will be a carrier and another will be hemophiliac
Among mary’s daughters, one will be a carrier and another will be normal
(e) the carrier daughter can transmit the disease to her son’s